Meis3 (Meis homeobox 3) - Rat Genome Database

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Gene: Meis3 (Meis homeobox 3) Rattus norvegicus
Analyze
Symbol: Meis3
Name: Meis homeobox 3
RGD ID: 1308532
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in several processes, including embryonic pattern specification; eye development; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of apoptotic signaling pathway and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in nucleus. Orthologous to several human genes including MEIS3 (Meis homeobox 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeobox protein Meis3; LOC361514; Meis1, myeloid ecotropic viral integration site 1 homolog 3; Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse); Mrg2; myeloid ecotropic viral integration site-related gene 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8185,986,602 - 86,000,873 (+)NCBIGRCr8
mRatBN7.2176,861,267 - 76,872,691 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,861,924 - 76,872,691 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,235,960 - 82,246,772 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0190,799,986 - 90,810,801 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,991,059 - 84,001,871 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,065,617 - 78,079,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,068,931 - 78,079,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,335,318 - 79,346,214 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,513,672 - 76,524,431 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,579,037 - 76,602,545 (+)NCBI
Celera171,352,130 - 71,362,888 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17178831   PMID:21059917  


Genomics

Comparative Map Data
Meis3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8185,986,602 - 86,000,873 (+)NCBIGRCr8
mRatBN7.2176,861,267 - 76,872,691 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,861,924 - 76,872,691 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,235,960 - 82,246,772 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0190,799,986 - 90,810,801 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,991,059 - 84,001,871 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,065,617 - 78,079,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,068,931 - 78,079,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,335,318 - 79,346,214 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,513,672 - 76,524,431 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,579,037 - 76,602,545 (+)NCBI
Celera171,352,130 - 71,362,888 (+)NCBICelera
Cytogenetic Map1q21NCBI
MEIS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381947,403,124 - 47,422,233 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1947,403,124 - 47,419,527 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,906,381 - 47,925,490 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,598,193 - 52,614,597 (-)NCBINCBI36Build 36hg18NCBI36
Celera1944,710,265 - 44,726,668 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1944,330,771 - 44,346,745 (-)NCBIHuRef
CHM1_11947,908,568 - 47,924,966 (-)NCBICHM1_1
T2T-CHM13v2.01950,228,571 - 50,253,087 (-)NCBIT2T-CHM13v2.0
Meis3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39715,908,684 - 15,920,435 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl715,909,015 - 15,920,429 (+)EnsemblGRCm39 Ensembl
GRCm38716,174,012 - 16,186,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,175,090 - 16,186,504 (+)EnsemblGRCm38mm10GRCm38
MGSCv37716,760,729 - 16,771,853 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,333,952 - 15,345,019 (+)NCBIMGSCv36mm8
Celera714,736,434 - 14,737,446 (-)NCBICelera
Cytogenetic Map7A2NCBI
cM Map78.76NCBI
Meis3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555741,273,321 - 1,282,455 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555741,273,321 - 1,282,454 (-)NCBIChiLan1.0ChiLan1.0
MEIS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22053,550,545 - 53,573,384 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11955,420,554 - 55,443,389 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01944,391,523 - 44,414,259 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11953,048,140 - 53,063,247 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,048,140 - 53,063,247 (-)Ensemblpanpan1.1panPan2
MEIS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11108,591,759 - 108,602,635 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1108,591,589 - 108,604,040 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,072,767 - 108,084,314 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,117,119 - 109,125,833 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,116,601 - 109,126,240 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11108,784,256 - 108,795,805 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01108,428,779 - 108,440,343 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,297,342 - 109,308,902 (+)NCBIUU_Cfam_GSD_1.0
Meis3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934919,477,686 - 19,487,633 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366641,095,772 - 1,105,808 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366641,095,815 - 1,105,751 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEIS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,175,928 - 53,188,406 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,175,920 - 53,188,455 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2648,817,091 - 48,842,383 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEIS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,730,208 - 40,747,086 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,729,230 - 40,746,741 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607320,464,484 - 20,481,274 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Meis3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,369,259 - 6,377,268 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,369,248 - 6,379,754 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Meis3
49 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:153
Interacting mature miRNAs:180
Transcripts:ENSRNOT00000039538, ENSRNOT00000068406
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat

Markers in Region
AI573393  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,872,526 - 76,872,639 (+)MAPPERmRatBN7.2
Rnor_6.0178,079,534 - 78,079,646NCBIRnor6.0
Rnor_5.0179,346,050 - 79,346,162UniSTSRnor5.0
RGSC_v3.4176,524,276 - 76,524,388UniSTSRGSC3.4
Celera171,362,733 - 71,362,845UniSTS
Cytogenetic Map1q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 2 2 3 2 66 10 30 2
Low 2 41 49 33 16 33 6 9 8 25 11 9 6
Below cutoff 6 6 6 2 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC160854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000039538   ⟹   ENSRNOP00000033135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,861,924 - 76,872,682 (+)Ensembl
Rnor_6.0 Ensembl178,068,931 - 78,079,689 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000068406   ⟹   ENSRNOP00000063858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,861,924 - 76,872,682 (+)Ensembl
Rnor_6.0 Ensembl178,069,193 - 78,079,862 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118727   ⟹   ENSRNOP00000096875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,863,372 - 76,872,691 (+)Ensembl
RefSeq Acc Id: NM_001108472   ⟹   NP_001101942
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,050 - 86,000,873 (+)NCBI
mRatBN7.2176,861,868 - 76,872,691 (+)NCBI
Rnor_6.0178,068,931 - 78,079,689 (+)NCBI
Rnor_5.0179,335,318 - 79,346,214 (+)NCBI
RGSC_v3.4176,513,672 - 76,524,431 (+)RGD
Celera171,352,130 - 71,362,888 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399601   ⟹   NP_001386530
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,341 - 86,000,873 (+)NCBI
mRatBN7.2176,862,159 - 76,872,691 (+)NCBI
RefSeq Acc Id: NM_001399602   ⟹   NP_001386531
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,341 - 86,000,873 (+)NCBI
mRatBN7.2176,862,159 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_006228351   ⟹   XP_006228413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,226 - 86,000,873 (+)NCBI
mRatBN7.2176,862,075 - 76,872,691 (+)NCBI
Rnor_6.0178,069,066 - 78,079,698 (+)NCBI
Rnor_5.0179,335,318 - 79,346,214 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081649   ⟹   XP_038937577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,989,965 - 86,000,873 (+)NCBI
mRatBN7.2176,861,267 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_039081657   ⟹   XP_038937585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,222 - 86,000,873 (+)NCBI
mRatBN7.2176,862,075 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_039081664   ⟹   XP_038937592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,350 - 86,000,873 (+)NCBI
mRatBN7.2176,862,075 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_039081673   ⟹   XP_038937601
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,350 - 86,000,873 (+)NCBI
mRatBN7.2176,862,075 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_039081690   ⟹   XP_038937618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,992,348 - 86,000,873 (+)NCBI
mRatBN7.2176,864,170 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_039081693   ⟹   XP_038937621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,992,348 - 86,000,873 (+)NCBI
mRatBN7.2176,864,170 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_039081694   ⟹   XP_038937622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,992,348 - 86,000,873 (+)NCBI
mRatBN7.2176,864,170 - 76,872,691 (+)NCBI
RefSeq Acc Id: XM_063266345   ⟹   XP_063122415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,219 - 86,000,873 (+)NCBI
RefSeq Acc Id: XM_063266346   ⟹   XP_063122416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,986,835 - 86,000,873 (+)NCBI
RefSeq Acc Id: XM_063266348   ⟹   XP_063122418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,990,226 - 86,000,873 (+)NCBI
RefSeq Acc Id: XM_063266349   ⟹   XP_063122419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,989,998 - 86,000,873 (+)NCBI
RefSeq Acc Id: XM_063266350   ⟹   XP_063122420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,986,602 - 85,998,414 (+)NCBI
RefSeq Acc Id: NP_001101942   ⟸   NM_001108472
- Peptide Label: isoform 2
- UniProtKB: D4A9U2 (UniProtKB/TrEMBL),   A6J899 (UniProtKB/TrEMBL),   A0A8I6AQ93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228413   ⟸   XM_006228351
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AQ93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063858   ⟸   ENSRNOT00000068406
RefSeq Acc Id: ENSRNOP00000033135   ⟸   ENSRNOT00000039538
RefSeq Acc Id: XP_038937577   ⟸   XM_039081649
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AQ93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937585   ⟸   XM_039081657
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AQ93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937592   ⟸   XM_039081664
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AQ93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937601   ⟸   XM_039081673
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AQ93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937618   ⟸   XM_039081690
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038937621   ⟸   XM_039081693
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038937622   ⟸   XM_039081694
- Peptide Label: isoform X11
RefSeq Acc Id: ENSRNOP00000096875   ⟸   ENSRNOT00000118727
RefSeq Acc Id: NP_001386530   ⟸   NM_001399601
- Peptide Label: isoform 1
- UniProtKB: B1H242 (UniProtKB/TrEMBL),   A0A8I6AQ93 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386531   ⟸   NM_001399602
- Peptide Label: isoform 3
- UniProtKB: A0A8I6AQ93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122420   ⟸   XM_063266350
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063122416   ⟸   XM_063266346
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063122419   ⟸   XM_063266349
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063122415   ⟸   XM_063266345
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063122418   ⟸   XM_063266348
- Peptide Label: isoform X5
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9U2-F1-model_v2 AlphaFold D4A9U2 1-378 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689732
Promoter ID:EPDNEW_R251
Type:initiation region
Name:Meis3_1
Description:Meis homeobox 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0178,069,186 - 78,069,246EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308532 AgrOrtholog
BioCyc Gene G2FUF-60621 BioCyc
Ensembl Genes ENSRNOG00000021390 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039538 ENTREZGENE
  ENSRNOT00000039538.7 UniProtKB/TrEMBL
  ENSRNOT00000068406 ENTREZGENE
  ENSRNOT00000068406.4 UniProtKB/TrEMBL
  ENSRNOT00000118727.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8364874 IMAGE-MGC_LOAD
InterPro Homeobox_KN_domain UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  PKNOX/Meis_N UniProtKB/TrEMBL
KEGG Report rno:361514 UniProtKB/TrEMBL
MGC_CLONE MGC:187606 IMAGE-MGC_LOAD
NCBI Gene 361514 ENTREZGENE
PANTHER HOMEOBOX PROTEIN MEIS3 UniProtKB/TrEMBL
  HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  Meis_PKNOX_N UniProtKB/TrEMBL
PhenoGen Meis3 PhenoGen
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021390 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A8I6AQ93 ENTREZGENE, UniProtKB/TrEMBL
  A6J899 ENTREZGENE, UniProtKB/TrEMBL
  B1H242 ENTREZGENE, UniProtKB/TrEMBL
  D4A9U2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Meis3  Meis homeobox 3  Meis3_predicted  Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Meis3_predicted  Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse) (predicted)  Mrg2_predicted  myeloid ecotropic viral integration site-related gene 2 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Mrg2_predicted  myeloid ecotropic viral integration site-related gene 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED