Pex5 (peroxisomal biogenesis factor 5) - Rat Genome Database

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Pathways
Gene: Pex5 (peroxisomal biogenesis factor 5) Rattus norvegicus
Analyze
Symbol: Pex5
Name: peroxisomal biogenesis factor 5
RGD ID: 1307612
Description: Predicted to enable peroxisome targeting sequence binding activity; protein carrier chaperone; and small GTPase binding activity. Predicted to be involved in several processes, including pexophagy; protein targeting to peroxisome; and protein tetramerization. Predicted to act upstream of or within several processes, including fatty acid metabolic process; mitochondrial membrane organization; and nervous system development. Located in peroxisomal membrane. Part of protein-containing complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103690024; peroxin-5; peroxisomal C-terminal targeting signal import receptor; peroxisomal targeting signal 1 receptor; peroxisomal targeting signal 1 receptor-like; peroxisome biogenesis factor 5; peroxisome receptor 1; PTS1 receptor; PTS1-BP; PTS1R
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24157,270,671 - 157,296,432 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,270,672 - 157,296,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,487,111 - 163,512,826 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,270,018 - 159,295,731 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04157,915,420 - 157,941,178 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04156,983,914 - 157,009,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,403,016 - 156,427,755 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,983,915 - 157,009,674 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,003,341 - 224,029,474 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04223,418,715 - 223,444,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,567,258 - 160,595,985 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14160,813,343 - 160,858,163 (-)NCBI
Celera4146,011,937 - 146,037,676 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. A mouse model for Zellweger syndrome. Baes M, etal., Nat Genet. 1997 Sep;17(1):49-57.
2. Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Baumgart E, etal., Am J Pathol. 2001 Oct;159(4):1477-94. doi: 10.1016/S0002-9440(10)62534-5.
3. Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities. Dirkx R, etal., Hepatology. 2005 Apr;41(4):868-78.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Hsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1. Harano T, etal., Biochem J. 2001 Jul 1;357(Pt 1):157-65.
7. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Hepatosteatosis in peroxisome deficient liver despite increased β-oxidation capacity and impaired lipogenesis. Peeters A, etal., Biochimie. 2011 Oct;93(10):1828-38. doi: 10.1016/j.biochi.2011.06.034. Epub 2011 Jul 5.
11. Characterization of the mammalian peroxisomal import machinery: Pex2p, Pex5p, Pex12p, and Pex14p are subunits of the same protein assembly. Reguenga C, etal., J Biol Chem. 2001 Aug 10;276(32):29935-42. Epub 2001 Jun 7.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites. Shinde AB, etal., Mitochondrion. 2018 Mar;39:51-59. doi: 10.1016/j.mito.2017.08.013. Epub 2017 Sep 1.
Additional References at PubMed
PMID:7719337   PMID:9668159   PMID:10514471   PMID:10562279   PMID:10653000   PMID:11060344   PMID:11336669   PMID:11420171   PMID:11463335   PMID:11669066   PMID:11829486   PMID:11931631  
PMID:12456682   PMID:12477932   PMID:12885776   PMID:14586000   PMID:14709540   PMID:15328363   PMID:16484321   PMID:17442273   PMID:17726030   PMID:18346465   PMID:19197237   PMID:19584060  
PMID:20178365   PMID:21375735   PMID:21525035   PMID:21976670   PMID:21980954   PMID:22371489   PMID:34174269  


Genomics

Comparative Map Data
Pex5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24157,270,671 - 157,296,432 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,270,672 - 157,296,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,487,111 - 163,512,826 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,270,018 - 159,295,731 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04157,915,420 - 157,941,178 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04156,983,914 - 157,009,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,403,016 - 156,427,755 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,983,915 - 157,009,674 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,003,341 - 224,029,474 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04223,418,715 - 223,444,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,567,258 - 160,595,985 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14160,813,343 - 160,858,163 (-)NCBI
Celera4146,011,937 - 146,037,676 (-)NCBICelera
Cytogenetic Map4q42NCBI
PEX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38127,188,653 - 7,218,574 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl127,188,685 - 7,218,574 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,341,249 - 7,371,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,234,225 - 7,255,343 (+)NCBINCBI36Build 36hg18NCBI36
Build 34127,234,223 - 7,255,342NCBI
Celera128,917,914 - 8,946,785 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef127,154,705 - 7,183,873 (+)NCBIHuRef
CHM1_1127,340,679 - 7,369,353 (+)NCBICHM1_1
T2T-CHM13v2.0127,201,809 - 7,231,939 (+)NCBIT2T-CHM13v2.0
Pex5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,373,774 - 124,392,878 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,373,775 - 124,392,026 (-)EnsemblGRCm39 Ensembl
GRCm386124,396,816 - 124,415,944 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,396,816 - 124,415,067 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,346,834 - 124,365,085 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,362,437 - 124,380,668 (-)NCBIMGSCv36mm8
Celera6126,087,349 - 126,105,596 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.15NCBI
Pex5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,736,189 - 4,755,766 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,736,189 - 4,755,559 (+)NCBIChiLan1.0ChiLan1.0
PEX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11212,750,866 - 12,771,857 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,318,637 - 7,340,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,235,049 - 7,255,815 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,235,049 - 7,255,815 (+)Ensemblpanpan1.1panPan2
PEX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,843,218 - 37,860,664 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,809,717 - 37,860,376 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,756,138 - 8,773,549 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,196,735 - 38,214,157 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,196,420 - 38,214,129 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,070,618 - 38,088,021 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,111,918 - 38,129,293 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,233,881 - 8,251,302 (+)NCBIUU_Cfam_GSD_1.0
Pex5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945101,919,747 - 101,938,591 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709587,295 - 606,247 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936709587,296 - 606,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,542,431 - 63,562,849 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,542,422 - 63,562,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,936,442 - 65,956,834 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,255,078 - 7,286,500 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,256,182 - 7,274,938 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666063923,792 - 955,255 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,771,963 - 3,790,985 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,771,949 - 3,790,982 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pex5
164 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1036
Count of miRNA genes:273
Interacting mature miRNAs:335
Transcripts:ENSRNOT00000071625, ENSRNOT00000073341
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat

Markers in Region
RH137207  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,270,840 - 157,271,050 (+)MAPPERmRatBN7.2
Rnor_6.04156,984,084 - 156,984,293NCBIRnor6.0
Rnor_6.04156,403,186 - 156,403,395NCBIRnor6.0
Rnor_5.04224,003,511 - 224,003,720UniSTSRnor5.0
Rnor_5.04223,418,885 - 223,419,094UniSTSRnor5.0
RGSC_v3.44160,567,428 - 160,567,637UniSTSRGSC3.4
Celera4146,012,107 - 146,012,316UniSTS
RH 3.4 Map41003.1UniSTS
Cytogenetic Map4q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 28 52 37 14 37 72 35 41 9
Below cutoff 2 15 5 4 5 4 8 11 2 2 8

Sequence


RefSeq Acc Id: ENSRNOT00000014028   ⟹   ENSRNOP00000014028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,270,672 - 157,296,431 (-)Ensembl
Rnor_6.0 Ensembl4156,403,016 - 156,426,760 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000014030   ⟹   ENSRNOP00000014030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4156,404,166 - 156,427,755 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000071625   ⟹   ENSRNOP00000064300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,270,672 - 157,296,431 (-)Ensembl
Rnor_6.0 Ensembl4156,983,915 - 157,009,674 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000073341   ⟹   ENSRNOP00000066869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4156,985,046 - 157,008,947 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085675   ⟹   ENSRNOP00000070292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4156,404,166 - 156,427,755 (-)Ensembl
RefSeq Acc Id: NM_001170584   ⟹   NP_001164055
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,270,671 - 157,296,431 (-)NCBI
Rnor_6.04156,983,914 - 157,009,674 (-)NCBI
Rnor_5.04223,418,715 - 223,444,193 (-)NCBI
Celera4146,011,937 - 146,037,676 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237384   ⟹   XP_006237446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,270,671 - 157,296,432 (-)NCBI
Rnor_6.04156,983,914 - 157,009,675 (-)NCBI
Rnor_5.04224,003,341 - 224,029,474 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237385   ⟹   XP_006237447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,270,671 - 157,296,195 (-)NCBI
Rnor_6.04156,983,914 - 157,009,415 (-)NCBI
Rnor_5.04224,003,341 - 224,029,474 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107672   ⟹   XP_038963600
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,270,671 - 157,296,326 (-)NCBI
RefSeq Acc Id: NP_001164055   ⟸   NM_001170584
- UniProtKB: Q2M2R8 (UniProtKB/Swiss-Prot),   M0R4L3 (UniProtKB/TrEMBL),   A6ILI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237446   ⟸   XM_006237384
- Peptide Label: isoform X1
- UniProtKB: Q2M2R8 (UniProtKB/Swiss-Prot),   A0A0A0MP84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237447   ⟸   XM_006237385
- Peptide Label: isoform X1
- UniProtKB: Q2M2R8 (UniProtKB/Swiss-Prot),   A0A0A0MP84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066869   ⟸   ENSRNOT00000073341
RefSeq Acc Id: ENSRNOP00000064300   ⟸   ENSRNOT00000071625
RefSeq Acc Id: XP_038963600   ⟸   XM_039107672
- Peptide Label: isoform X2
- UniProtKB: Q2M2R8 (UniProtKB/Swiss-Prot),   M0R4L3 (UniProtKB/TrEMBL),   A6ILI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000070292   ⟸   ENSRNOT00000085675
RefSeq Acc Id: ENSRNOP00000014030   ⟸   ENSRNOT00000014030
RefSeq Acc Id: ENSRNOP00000014028   ⟸   ENSRNOT00000014028

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2M2R8-F1-model_v2 AlphaFold Q2M2R8 1-640 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307612 AgrOrtholog
BioCyc Gene G2FUF-43110 BioCyc
Ensembl Genes ENSRNOG00000010407 Ensembl
  ENSRNOG00000049203 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014028 ENTREZGENE
  ENSRNOP00000014028.5 UniProtKB/TrEMBL
  ENSRNOP00000064300 ENTREZGENE
  ENSRNOP00000064300.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014028 ENTREZGENE
  ENSRNOT00000014028.7 UniProtKB/TrEMBL
  ENSRNOT00000071625 ENTREZGENE
  ENSRNOT00000071625.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7369235 IMAGE-MGC_LOAD
InterPro PTS1R_family UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:312703 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:125175 IMAGE-MGC_LOAD
NCBI Gene 312703 ENTREZGENE
PANTHER PTHR10130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10130:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TPR_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pex5 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MP84 ENTREZGENE
  A0A9M1WVX5_RAT UniProtKB/TrEMBL
  A6ILI2 ENTREZGENE, UniProtKB/TrEMBL
  M0R4L3 ENTREZGENE, UniProtKB/TrEMBL
  PEX5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pex5  peroxisomal biogenesis factor 5  LOC103690024  peroxisomal targeting signal 1 receptor-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103690024  peroxisomal targeting signal 1 receptor-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-10-24 Pex5  peroxisomal biogenesis factor 5  Pex5  peroxisome biogenesis factor 5   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pex5  peroxisome biogenesis factor 5   Pex5_predicted  peroxisome biogenesis factor 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pex5_predicted  peroxisome biogenesis factor 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED