Lcp2 (lymphocyte cytosolic protein 2) - Rat Genome Database

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Gene: Lcp2 (lymphocyte cytosolic protein 2) Rattus norvegicus
Analyze
Symbol: Lcp2
Name: lymphocyte cytosolic protein 2
RGD ID: 619743
Description: Predicted to be involved in cell surface receptor signaling pathway; intracellular signal transduction; and positive regulation of protein kinase activity. Predicted to act upstream of or within mast cell activation. Predicted to be located in cell-cell junction; cytosol; and plasma membrane raft. Predicted to be part of TCR signalosome. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human LCP2 (lymphocyte cytosolic protein 2); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); Slp76
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81019,146,846 - 19,193,750 (+)NCBIGRCr8
mRatBN7.21018,642,600 - 18,689,562 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1018,642,658 - 18,689,559 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1023,397,681 - 23,444,529 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01022,886,235 - 22,933,080 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01018,366,466 - 18,413,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,996,523 - 19,043,289 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,996,523 - 19,043,286 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01018,875,179 - 18,921,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41019,019,978 - 19,066,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11019,021,186 - 19,066,146 (+)NCBI
Celera1018,275,491 - 18,322,327 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells. Hendricks-Taylor LR, etal., J Biol Chem 1997 Jan 10;272(2):1363-7.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14624253   PMID:15153494   PMID:20551903   PMID:23793062   PMID:25916191  


Genomics

Comparative Map Data
Lcp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81019,146,846 - 19,193,750 (+)NCBIGRCr8
mRatBN7.21018,642,600 - 18,689,562 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1018,642,658 - 18,689,559 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1023,397,681 - 23,444,529 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01022,886,235 - 22,933,080 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01018,366,466 - 18,413,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,996,523 - 19,043,289 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,996,523 - 19,043,286 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01018,875,179 - 18,921,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41019,019,978 - 19,066,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11019,021,186 - 19,066,146 (+)NCBI
Celera1018,275,491 - 18,322,327 (+)NCBICelera
Cytogenetic Map10q12NCBI
LCP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385170,246,233 - 170,297,777 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5170,246,233 - 170,297,815 (-)EnsemblGRCh38hg38GRCh38
GRCh375169,673,237 - 169,724,781 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365169,607,666 - 169,657,400 (-)NCBINCBI36Build 36hg18NCBI36
Build 345169,607,666 - 169,657,400NCBI
Celera5165,707,014 - 165,756,761 (-)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5164,773,564 - 164,823,697 (-)NCBIHuRef
CHM1_15169,107,544 - 169,157,743 (-)NCBICHM1_1
T2T-CHM13v2.05170,785,090 - 170,836,631 (-)NCBIT2T-CHM13v2.0
Lcp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,996,928 - 34,042,281 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,996,920 - 34,042,295 (+)EnsemblGRCm39 Ensembl
GRCm381134,046,928 - 34,092,281 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,046,920 - 34,092,295 (+)EnsemblGRCm38mm10GRCm38
MGSCv371133,947,201 - 33,992,280 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361133,947,201 - 33,992,280 (+)NCBIMGSCv36mm8
Celera1136,458,439 - 36,503,504 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.43NCBI
Lcp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540823,200,828 - 23,245,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540823,200,137 - 23,246,032 (-)NCBIChiLan1.0ChiLan1.0
LCP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24165,403,067 - 165,452,899 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15163,542,610 - 163,592,442 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05165,605,590 - 165,655,378 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15172,365,176 - 172,605,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5172,365,794 - 172,414,585 (-)Ensemblpanpan1.1panPan2
LCP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1441,611,674 - 41,656,792 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl441,611,775 - 41,656,364 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha441,563,966 - 41,608,906 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0441,987,824 - 42,032,727 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl441,987,936 - 42,034,116 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1441,805,072 - 41,849,960 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0441,991,912 - 42,036,798 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0442,502,525 - 42,547,496 (+)NCBIUU_Cfam_GSD_1.0
Lcp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721395,799,447 - 95,841,703 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366094,522,385 - 4,563,765 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366094,522,158 - 4,565,505 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LCP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1653,697,026 - 53,741,725 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11653,696,974 - 53,741,736 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21658,039,094 - 58,083,594 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LCP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12372,450,399 - 72,499,775 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2372,451,013 - 72,499,735 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660346,162,206 - 6,212,521 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lcp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473319,672,868 - 19,719,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473319,625,276 - 19,720,125 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lcp2
297 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:197
Count of miRNA genes:131
Interacting mature miRNAs:158
Transcripts:ENSRNOT00000046135
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101724551319388279Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat

Markers in Region
RH141536  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21018,687,880 - 18,688,042 (+)MAPPERmRatBN7.2
Rnor_6.01019,041,608 - 19,041,769NCBIRnor6.0
Rnor_5.01018,920,264 - 18,920,425UniSTSRnor5.0
RGSC_v3.41019,065,063 - 19,065,224UniSTSRGSC3.4
Celera1018,320,646 - 18,320,807UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000046135   ⟹   ENSRNOP00000050879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1018,642,658 - 18,689,559 (+)Ensembl
Rnor_6.0 Ensembl1018,996,523 - 19,043,286 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117988   ⟹   ENSRNOP00000089559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1018,642,658 - 18,689,559 (+)Ensembl
RefSeq Acc Id: NM_130421   ⟹   NP_569105
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81019,146,846 - 19,193,750 (+)NCBI
mRatBN7.21018,642,658 - 18,689,562 (+)NCBI
Rnor_6.01018,996,523 - 19,043,289 (+)NCBI
Rnor_5.01018,875,179 - 18,921,945 (+)NCBI
RGSC_v3.41019,019,978 - 19,066,744 (+)RGD
Celera1018,275,491 - 18,322,327 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_569105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00067 (Get FASTA)   NCBI Sequence Viewer  
  BAB71779 (Get FASTA)   NCBI Sequence Viewer  
  EDM04082 (Get FASTA)   NCBI Sequence Viewer  
  EDM04083 (Get FASTA)   NCBI Sequence Viewer  
  EDM04084 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000050879.5
  ENSRNOP00000089559.1
RefSeq Acc Id: NP_569105   ⟸   NM_130421
- UniProtKB: F1LNJ9 (UniProtKB/TrEMBL),   A0A8J8YIH6 (UniProtKB/TrEMBL),   Q920L0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050879   ⟸   ENSRNOT00000046135
Ensembl Acc Id: ENSRNOP00000089559   ⟸   ENSRNOT00000117988
Protein Domains
SAM   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q920L0-F1-model_v2 AlphaFold Q920L0 1-525 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697098
Promoter ID:EPDNEW_R7623
Type:initiation region
Name:Lcp2_1
Description:lymphocyte cytosolic protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01018,996,516 - 18,996,576EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619743 AgrOrtholog
BioCyc Gene G2FUF-25590 BioCyc
Ensembl Genes ENSRNOG00000005620 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046135.5 UniProtKB/TrEMBL
  ENSRNOT00000117988.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7387128 IMAGE-MGC_LOAD
InterPro Immunoreceptor_sig_adapters UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM_type UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
KEGG Report rno:155918 UniProtKB/TrEMBL
MGC_CLONE MGC:112603 IMAGE-MGC_LOAD
NCBI Gene 155918 ENTREZGENE
PANTHER LYMPHOCYTE CYTOSOLIC PROTEIN 2 UniProtKB/TrEMBL
  SH2 DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam SAM_2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PhenoGen Lcp2 PhenoGen
PRINTS SH2DOMAIN UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005620 RatGTEx
SMART SAM UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
Superfamily-SCOP SAM_homology UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8I6AC21_RAT UniProtKB/TrEMBL
  A0A8J8YIH6 ENTREZGENE, UniProtKB/TrEMBL
  A6HDH6_RAT UniProtKB/TrEMBL
  A6HDH7_RAT UniProtKB/TrEMBL
  A6HDH8_RAT UniProtKB/TrEMBL
  F1LNJ9 ENTREZGENE
  Q920L0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LNJ9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Lcp2  lymphocyte cytosolic protein 2    lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD)  Name updated 1299863 APPROVED
2002-08-07 Lcp2  lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction interacts with the Grb2 adapter protein in the mast cells 724419