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Gene: Irak2 (interleukin-1 receptor-associated kinase 2) Rattus norvegicus
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Symbol: Irak2
Name: interleukin-1 receptor-associated kinase 2
RGD ID: 1309584
Description: Predicted to have protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; regulation of DNA-binding transcription factor activity; and regulation of cytokine-mediated signaling pathway. Predicted to localize to cytoplasm; nucleus; and plasma membrane. Orthologous to human IRAK2 (interleukin 1 receptor associated kinase 2); PARTICIPATES IN interleukin-1 signaling pathway; Toll-like receptor signaling pathway; apoptotic cell death pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: interleukin-1 receptor-associated kinase-like 2; IRAK-2; LOC362418
Orthologs:
Homo sapiens (human) : IRAK2 (interleukin 1 receptor associated kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Irak2 (interleukin-1 receptor-associated kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irak2 (interleukin 1 receptor associated kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IRAK2 (interleukin 1 receptor associated kinase 2)
Canis lupus familiaris (dog) : VHL (von Hippel-Lindau tumor suppressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irak2 (interleukin 1 receptor associated kinase 2)
Sus scrofa (pig) : IRAK2 (interleukin 1 receptor associated kinase 2)
Chlorocebus sabaeus (African green monkey) : IRAK2 (interleukin 1 receptor associated kinase 2)
Heterocephalus glaber (naked mole-rat) : Irak2 (interleukin 1 receptor associated kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04145,594,575 - 145,651,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,594,575 - 145,651,053 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04208,890,974 - 208,947,453 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,543,029 - 149,599,463 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14149,787,869 - 149,844,303 (+)NCBI
Celera4135,340,439 - 135,396,939 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Irak2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309584
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.