Emg1 (EMG1 N1-specific pseudouridine methyltransferase) - Rat Genome Database

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Gene: Emg1 (EMG1 N1-specific pseudouridine methyltransferase) Rattus norvegicus
Analyze
Symbol: Emg1
Name: EMG1 N1-specific pseudouridine methyltransferase
RGD ID: 1307665
Description: Predicted to enable identical protein binding activity; rRNA (pseudouridine) methyltransferase activity; and rRNA binding activity. Predicted to be involved in rRNA base methylation and ribosomal small subunit biogenesis. Predicted to act upstream of or within blastocyst development and nucleologenesis. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Bowen-Conradi syndrome. Orthologous to human EMG1 (EMG1 N1-specific pseudouridine methyltransferase); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EMG1 nucleolar protein homolog; EMG1 nucleolar protein homolog (S. cerevisiae); gene rich cluster, C2f; gene rich cluster, C2f gene; Grcc2f; LOC312706; probable ribosome biogenesis protein NEP1; ribosomal RNA small subunit methyltransferase NEP1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,195,545 - 159,203,826 (-)NCBIGRCr8
mRatBN7.24157,509,258 - 157,517,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,509,277 - 157,517,540 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,737,748 - 163,746,028 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,520,654 - 159,528,933 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,162,220 - 158,170,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,222,366 - 157,230,647 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,222,385 - 157,230,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,239,962 - 224,248,243 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,826,925 - 160,835,206 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,072,842 - 161,080,012 (-)NCBI
Celera4146,247,921 - 146,256,202 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP,ISO)
dexamethasone  (ISO)
diethyl malate  (ISO)
folic acid  (ISO)
genistein  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
menadione  (ISO)
methimazole  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA)
small-subunit processome  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20047967   PMID:20858271   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Emg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,195,545 - 159,203,826 (-)NCBIGRCr8
mRatBN7.24157,509,258 - 157,517,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,509,277 - 157,517,540 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,737,748 - 163,746,028 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,520,654 - 159,528,933 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,162,220 - 158,170,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,222,366 - 157,230,647 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,222,385 - 157,230,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,239,962 - 224,248,243 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,826,925 - 160,835,206 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,072,842 - 161,080,012 (-)NCBI
Celera4146,247,921 - 146,256,202 (-)NCBICelera
Cytogenetic Map4q42NCBI
EMG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,970,913 - 6,997,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,970,913 - 6,979,936 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,080,076 - 7,105,520 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,950,255 - 6,955,404 (+)NCBINCBI36Build 36hg18NCBI36
Celera128,700,963 - 8,706,185 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,938,409 - 6,943,631 (+)NCBIHuRef
CHM1_1127,078,897 - 7,084,119 (+)NCBICHM1_1
T2T-CHM13v2.0126,984,388 - 7,010,891 (+)NCBIT2T-CHM13v2.0
Emg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,681,344 - 124,689,118 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,681,048 - 124,689,141 (-)EnsemblGRCm39 Ensembl
GRCm386124,704,370 - 124,712,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,704,085 - 124,712,178 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,654,388 - 124,662,196 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,670,006 - 124,677,746 (-)NCBIMGSCv36mm8
Celera6126,386,095 - 126,393,903 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Emg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,563,864 - 4,570,809 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,563,864 - 4,570,809 (+)NCBIChiLan1.0ChiLan1.0
EMG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,536,820 - 12,542,053 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,533,579 - 12,538,816 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,102,619 - 7,108,594 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,018,291 - 7,023,807 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,018,291 - 7,023,807 (+)Ensemblpanpan1.1panPan2
EMG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,069,089 - 38,075,577 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,068,231 - 38,076,300 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,541,114 - 8,547,601 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,421,686 - 38,428,179 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,421,686 - 38,428,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,296,590 - 38,303,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,337,556 - 38,344,041 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,019,877 - 8,026,362 (+)NCBIUU_Cfam_GSD_1.0
Emg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,179,680 - 102,186,891 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709845,633 - 854,976 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709847,229 - 854,471 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,745,476 - 63,751,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,746,326 - 63,751,469 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,182,467 - 66,187,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EMG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,004,507 - 7,009,702 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,004,645 - 7,009,527 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,206,934 - 1,213,103 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Emg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,605,126 - 3,611,108 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,605,114 - 3,611,108 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Emg1
22 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:92
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000017334
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat

Markers in Region
RH140480  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,513,016 - 157,513,106 (+)MAPPERmRatBN7.2
Rnor_6.04157,226,124 - 157,226,213NCBIRnor6.0
Rnor_5.04224,243,720 - 224,243,809UniSTSRnor5.0
RGSC_v3.44160,830,683 - 160,830,772UniSTSRGSC3.4
Celera4146,251,679 - 146,251,768UniSTS
RH 3.4 Map41002.9UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017334   ⟹   ENSRNOP00000017334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,509,277 - 157,517,540 (-)Ensembl
Rnor_6.0 Ensembl4157,222,385 - 157,230,647 (-)Ensembl
RefSeq Acc Id: NM_001107888   ⟹   NP_001101358
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,195,545 - 159,203,826 (-)NCBI
mRatBN7.24157,509,258 - 157,517,540 (-)NCBI
Rnor_6.04157,222,366 - 157,230,647 (-)NCBI
Rnor_5.04224,239,962 - 224,248,243 (-)NCBI
RGSC_v3.44160,826,925 - 160,835,206 (-)RGD
Celera4146,247,921 - 146,256,202 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101358 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM01947 (Get FASTA)   NCBI Sequence Viewer  
  EDM01948 (Get FASTA)   NCBI Sequence Viewer  
  EDM01949 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017334.4
RefSeq Acc Id: NP_001101358   ⟸   NM_001107888
- UniProtKB: D3ZDS4 (UniProtKB/TrEMBL),   A6ILJ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017334   ⟸   ENSRNOT00000017334

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDS4-F1-model_v2 AlphaFold D3ZDS4 1-244 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693385
Promoter ID:EPDNEW_R3909
Type:multiple initiation site
Name:Emg1_1
Description:EMG1 N1-specific pseudouridine methyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04157,230,528 - 157,230,588EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307665 AgrOrtholog
BioCyc Gene G2FUF-43090 BioCyc
Ensembl Genes ENSRNOG00000012828 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017334.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1280.10 UniProtKB/TrEMBL
InterPro Alpha/beta_knot_MTases UniProtKB/TrEMBL
  Rbsml_bgen_MeTrfase_EMG1/NEP1 UniProtKB/TrEMBL
  tRNA_m1G_MTases_N UniProtKB/TrEMBL
KEGG Report rno:312706 UniProtKB/TrEMBL
NCBI Gene 312706 ENTREZGENE
PANTHER Mra1 UniProtKB/TrEMBL
  RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 UniProtKB/TrEMBL
Pfam EMG1 UniProtKB/TrEMBL
PhenoGen Emg1 PhenoGen
RatGTEx ENSRNOG00000012828 RatGTEx
Superfamily-SCOP SSF75217 UniProtKB/TrEMBL
UniProt A6ILJ1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDS4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-05 Emg1  EMG1 N1-specific pseudouridine methyltransferase  Emg1  EMG1 nucleolar protein homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Emg1  EMG1 nucleolar protein homolog (S. cerevisiae)   Emg1_predicted  EMG1 nucleolar protein homolog (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Emg1_predicted  EMG1 nucleolar protein homolog (S. cerevisiae) (predicted)  Grcc2f_predicted  gene rich cluster, C2f gene (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Grcc2f_predicted  gene rich cluster, C2f gene (predicted)      Symbol and Name status set to approved 70820 APPROVED