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Gene: Emg1 (EMG1 N1-specific pseudouridine methyltransferase) Mus musculus
Symbol: Emg1
Name: EMG1 N1-specific pseudouridine methyltransferase
Description: Predicted to have rRNA (pseudouridine) methyltransferase activity and rRNA binding activity. Involved in blastocyst development and nucleologenesis. Predicted to localize to the nucleolus; nucleoplasm; and small-subunit processome. Used to study Bowen-Conradi syndrome. Human ortholog(s) of this gene implicated in Bowen-Conradi syndrome. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and neural retina. Orthologous to human EMG1 (EMG1 N1-specific pseudouridine methyltransferase); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 18S rRNA (pseudouridine(1248)-N1)-methyltransferase; 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1; 18S rRNA Psi1248 methyltransferase; C2f; EMG1 nucleolar protein homolog; gene rich cluster, C2f; Grcc2f; nucleolar protein EMG1 homolog; probable ribosome biogenesis protein NEP1; ribosomal RNA small subunit methyltransferase NEP1; ribosome biogenesis protein NEP1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm386124,704,370 - 124,712,186 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376124,654,388 - 124,662,196 (-)NCBIGRCm37mm9NCBIm37
MGSCv366124,670,006 - 124,677,746 (-)NCBImm8
Celera6126,386,095 - 126,393,903 (-)NCBICelera
Cytogenetic Map6 F2NCBI
cM Map659.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Emg1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316987
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.