Gene: Tlr5 (toll-like receptor 5) Rattus norvegicus
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Symbol: Tlr5
Name: toll-like receptor 5
Description: Predicted to have interleukin-1 receptor binding activity. Involved in cellular response to lipopolysaccharide; male gonad development; and positive regulation of nitric oxide biosynthetic process. Localizes to the membrane. Biomarker of melioidosis and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in Legionnaires' disease; cystic fibrosis; cystitis; melioidosis; and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH aflatoxin B1; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : TLR5 (toll like receptor 5)  HGNC  Alliance
Mus musculus (house mouse) : Tlr5 (toll-like receptor 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr5 (toll like receptor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR5 (toll like receptor 5)
Canis lupus familiaris (dog) : TLR5 (toll like receptor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr5 (toll like receptor 5)
Sus scrofa (pig) : TLR5 (toll like receptor 5)
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Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013101,364,784 - 101,385,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013106,294,254 - 106,315,238 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41399,025,501 - 99,029,755 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11399,217,286 - 99,217,523 (+)NCBI
Celera1394,180,743 - 94,184,997 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tlr5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631351
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.