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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr5
Name: toll-like receptor 5
Acc ID: CHEBI:6801
Term: metformin
Definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chemical ID: MESH:D008687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr5multiple interactionsISOTLR5 (Homo sapiens)6480464CTD[Paclitaxel co-treated with Metformin] results in increased expression of TLR5 mRNAPMID:29309887
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