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Gene: Tlr5 (toll like receptor 5) Ictidomys tridecemlineatus

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Symbol:

Tlr5

Name:

toll like receptor 5

RGD ID:

12641487

Description:

ENCODES a protein that exhibits interleukin-1 receptor binding (inferred); pattern recognition receptor activity (inferred); signaling receptor activity (inferred); INVOLVED IN cellular response to lipopolysaccharide (ortholog); male gonad development (ortholog); positive regulation of nitric oxide biosynthetic process (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH adult respiratory distress syndrome (ortholog); alcohol use disorder (ortholog); ankylosing spondylitis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

toll-like receptor 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TLR5 (toll like receptor 5)	NCBI	Ortholog
Mus musculus (house mouse):	Tlr5 (toll-like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tlr5 (toll-like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tlr5 (toll like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TLR5 (toll like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TLR5 (toll like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TLR5 (toll like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TLR5 (toll like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tlr5 (toll like receptor 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	54,334,832 - 54,363,906 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	383,418 - 401,552 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	383,490 - 387,007 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	adult respiratory distress syndrome		ISO	Tlr5 (Mus musculus)	9068941	mRNA:decreased expression:lung (mouse)	RGD	PMID:12763043 and REF_RGD_ID:5129557
Tlr5	Squirrel	alcohol use disorder		ISO	TLR5 (Homo sapiens)	9068941	mRNA:increased expression:orbitofrontal cortex	RGD	PMID:34415075 and REF_RGD_ID:597538499
Tlr5	Squirrel	ankylosing spondylitis		ISO	TLR5 (Homo sapiens)	9068941	mRNA:increased expression:blood cell:	RGD	PMID:20952467 and REF_RGD_ID:7794744
Tlr5	Squirrel	Bacterial Keratitis		ISO	Tlr5 (Mus musculus)	9068941	associated with Serratia Infections	RGD	PMID:23033384 and REF_RGD_ID:8662876
Tlr5	Squirrel	bacterial pneumonia		ISO	Tlr5 (Mus musculus)	9068941		RGD	PMID:19801452 and REF_RGD_ID:5129503
Tlr5	Squirrel	chronic granulomatous disease		ISO	TLR5 (Homo sapiens)	9068941	protein:decreased expression:blood and neutrophil (human)	RGD	PMID:18155283 and REF_RGD_ID:5130865
Tlr5	Squirrel	cystic fibrosis		ISO	TLR5 (Homo sapiens)	9068941	protein:increased expression:lung more ...	RGD	PMID:18684966 and REF_RGD_ID:5129506
Tlr5	Squirrel	cystic fibrosis	resistance	ISO	TLR5 (Homo sapiens)	9068941	DNA:snp:cds:c.1174C>T rs5744168 (human)	RGD	PMID:21068401 and REF_RGD_ID:5129499
Tlr5	Squirrel	cystitis	severity	ISO	TLR5 (Homo sapiens)	9068941	DNA:nonsense mutation:cds:p.R392X (human)	RGD	PMID:19543401 and REF_RGD_ID:7246906
Tlr5	Squirrel	membranoproliferative glomerulonephritis		ISO	Tlr5 (Mus musculus)	9068941	mRNA:increased expression:renal glomerulus (mouse)	RGD	PMID:18256364 and REF_RGD_ID:7246909
Tlr5	Squirrel	perinatal necrotizing enterocolitis		ISO	Tlr5 (Rattus norvegicus)	9068941	mRNA:decreased expression:ileum (rat)	RGD	PMID:19608731 and REF_RGD_ID:5128779
Tlr5	Squirrel	Pseudomonas Infections		ISO	Tlr5 (Mus musculus)	9068941		RGD	PMID:20566829 and REF_RGD_ID:5129679
Tlr5	Squirrel	Salmonella Infections, Animal		ISO	Tlr5 (Rattus norvegicus)	9068941	mRNA more ...	RGD	PMID:20529359 and REF_RGD_ID:5129497
Tlr5	Squirrel	Tongue Neoplasms		ISO	TLR5 (Homo sapiens)	9068941	protein:increased expression:tongue:	RGD	PMID:23287987 and REF_RGD_ID:7814374
Tlr5	Squirrel	Viral Bronchiolitis	susceptibility	ISO	TLR5 (Homo sapiens)	9068941	DNA:snp:cds:p.F616L rs5744174 (human)	RGD	PMID:19258923 and REF_RGD_ID:4142862

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	gastrointestinal stromal tumor		ISO	TLR5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Gastrointestinal stromal tumor	ClinVar	PMID:28492532
Tlr5	Squirrel	Legionnaires' disease		ISO	TLR5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Legionnaire disease and susceptibility to	ClinVar	PMID:14623910 more ...
Tlr5	Squirrel	melioidosis		ISO	TLR5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Melioidosis and resistance to	ClinVar	PMID:14623910 more ...
Tlr5	Squirrel	parathyroid carcinoma		ISO	TLR5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Parathyroid carcinoma	ClinVar	PMID:28492532
Tlr5	Squirrel	systemic lupus erythematosus		ISO	TLR5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Systemic lupus erythematosus more ...	ClinVar	PMID:14623910 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	Chemical and Drug Induced Liver Injury		ISO	TLR5 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30508503
Tlr5	Squirrel	Hyperammonemia		ISO	TLR5 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30508503
Tlr5	Squirrel	Prostatic Neoplasms		ISO	TLR5 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16284379

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	Legionnaires' disease	susceptibility	ISO	TLR5 (Homo sapiens)	7240710		OMIM
Tlr5	Squirrel	melioidosis	susceptibility	ISO	TLR5 (Homo sapiens)	7240710		OMIM
Tlr5	Squirrel	systemic lupus erythematosus	susceptibility	ISO	TLR5 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	cellular response to lipopolysaccharide		ISO	Tlr5 (Rattus norvegicus)	9068941		RGD	PMID:21308757 and REF_RGD_ID:5129495
Tlr5	Squirrel	cellular response to mechanical stimulus	involved_in	IEA	UniProtKB:O60602 and ensembl:ENSP00000496355	150520179		Ensembl	GO_REF:0000107
Tlr5	Squirrel	immune response	involved_in	IEA	InterPro:IPR017241	150520179		InterPro	GO_REF:0000002
Tlr5	Squirrel	immune response	involved_in	IEA	UniRule:UR000001599	150520179		UniProt	GO_REF:0000104
Tlr5	Squirrel	immune system process	involved_in	IEA	UniProtKB-KW:KW-0391	150520179		UniProt	GO_REF:0000043
Tlr5	Squirrel	inflammatory response	involved_in	IEA	UniRule:UR000001599	150520179		UniProt	GO_REF:0000104
Tlr5	Squirrel	inflammatory response	involved_in	IEA	PANTHER:PTN000687390	150520179		TreeGrafter	GO_REF:0000118
Tlr5	Squirrel	inflammatory response	involved_in	IEA	UniProtKB-KW:KW-0395	150520179		UniProt	GO_REF:0000043
Tlr5	Squirrel	innate immune response	involved_in	IEA	UniRule:UR000001599	150520179		UniProt	GO_REF:0000104
Tlr5	Squirrel	innate immune response	involved_in	IEA	UniProtKB-KW:KW-0399	150520179		UniProt	GO_REF:0000043
Tlr5	Squirrel	male gonad development		ISO	Tlr5 (Rattus norvegicus)	9068941	epididymus	RGD	PMID:19703144 and REF_RGD_ID:5129498
Tlr5	Squirrel	positive regulation of cytokine production	involved_in	IEA	ARBA:ARBA00028861	150520179		UniProt	GO_REF:0000117
Tlr5	Squirrel	positive regulation of interleukin-8 production	acts_upstream_of	IEA	UniProtKB:O60602 and ensembl:ENSP00000496355	150520179		Ensembl	GO_REF:0000107
Tlr5	Squirrel	positive regulation of nitric oxide biosynthetic process		ISO	Tlr5 (Rattus norvegicus)	9068941		RGD	PMID:16973131 and REF_RGD_ID:1643119
Tlr5	Squirrel	regulation of tumor necrosis factor production	involved_in	IEA	ARBA:ARBA00034607	150520179		UniProt	GO_REF:0000117
Tlr5	Squirrel	signal transduction	involved_in	IEA	InterPro:IPR000157	150520179		InterPro	GO_REF:0000002
Tlr5	Squirrel	signal transduction	involved_in	IEA	PANTHER:PTN000687390	150520179		TreeGrafter	GO_REF:0000118
Tlr5	Squirrel	toll-like receptor 5 signaling pathway	involved_in	IEA	UniProtKB:O60602 and ensembl:ENSP00000496355	150520179		Ensembl	GO_REF:0000107
Tlr5	Squirrel	toll-like receptor signaling pathway	involved_in	IEA	InterPro:IPR017241	150520179		InterPro	GO_REF:0000002
Tlr5	Squirrel	toll-like receptor signaling pathway	involved_in	IEA	PANTHER:PTN000687390	150520179		TreeGrafter	GO_REF:0000118

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	150520179		UniProt	GO_REF:0000044
Tlr5	Squirrel	membrane	located_in	IEA	InterPro:IPR017241	150520179		InterPro	GO_REF:0000002
Tlr5	Squirrel	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
Tlr5	Squirrel	plasma membrane	is_active_in	IEA	UniProtKB:O60602 and ensembl:ENSP00000496355	150520179		Ensembl	GO_REF:0000107
Tlr5	Squirrel	plasma membrane	located_in	IEA	PANTHER:PTN000687390	150520179		TreeGrafter	GO_REF:0000118

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	interleukin-1 receptor binding	enables	IEA	UniProtKB:O60602 and ensembl:ENSP00000496355	150520179		Ensembl	GO_REF:0000107
Tlr5	Squirrel	pattern recognition receptor activity	enables	IEA	UniProtKB:O60602 and ensembl:ENSP00000496355	150520179		Ensembl	GO_REF:0000107
Tlr5	Squirrel	protein binding	enables	ISO	UniProtKB:A0A0H3NMJ6 and UniProtKB:Q56086	9068941	PMID:23101627	IntAct	PMID:23101627
Tlr5	Squirrel	protein binding	enables	ISO	UniProtKB:P05067-PRO_0000000092 and UniProtKB:P05067-PRO_0000000093	9068941	PMID:30158114	IntAct	PMID:30158114
Tlr5	Squirrel	signaling receptor activity	enables	IEA	PANTHER:PTN000687390	150520179		TreeGrafter	GO_REF:0000118
Tlr5	Squirrel	transmembrane signaling receptor activity	enables	IEA	InterPro:IPR017241	150520179		InterPro	GO_REF:0000002

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tlr5	Squirrel	Toll-like receptor signaling pathway		ISO	Tlr5 (Rattus norvegicus)	9068941		RGD	PMID:16973131 and REF_RGD_ID:1643119
Tlr5	Squirrel	Toll-like receptor signaling pathway		ISO	TLR5 (Homo sapiens)	9068941		RGD	PMID:21235323 and REF_RGD_ID:5685014

PMID:22301074	PMID:30032202

Tlr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	54,334,832 - 54,363,906 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	383,418 - 401,552 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	383,490 - 387,007 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TLR5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	223,109,404 - 223,143,248 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	223,109,404 - 223,143,292 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	223,282,746 - 223,316,590 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	221,350,207 - 221,383,247 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	196,502,104 - 196,535,977 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	193,957,238 - 193,991,230 (-)	NCBI		HuRef
CHM1_1	1	224,555,804 - 224,589,771 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	222,347,318 - 222,381,267 (-)	NCBI		T2T-CHM13v2.0

Tlr5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	182,782,317 - 182,804,010 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	182,782,353 - 182,804,010 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	182,954,752 - 182,976,044 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	182,954,788 - 182,976,044 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	184,884,919 - 184,906,175 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	184,884,919 - 184,906,170 (+)	NCBI		MGSCv36	mm8
Celera	1	189,998,902 - 190,020,262 (+)	NCBI		Celera
Cytogenetic Map	1	H5	NCBI
cM Map	1	86.12	NCBI

Tlr5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	97,166,430 - 97,190,642 (+)	NCBI		GRCr8
mRatBN7.2	13	94,634,778 - 94,658,992 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	94,634,801 - 94,657,738 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	97,156,784 - 97,161,038 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	98,556,697 - 98,560,951 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	95,738,872 - 95,743,126 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	101,364,784 - 101,385,764 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	101,381,510 - 101,385,764 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	106,294,254 - 106,315,238 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	99,025,501 - 99,029,755 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	99,217,286 - 99,217,523 (+)	NCBI
Celera	13	94,180,743 - 94,184,997 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

Tlr5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955520	1,556,523 - 1,559,093 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955520	1,544,840 - 1,562,081 (+)	NCBI	ChiLan1.0	ChiLan1.0

TLR5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	26,171,713 - 26,204,781 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	26,127,751 - 26,160,814 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	198,787,046 - 198,819,537 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	203,797,720 - 203,831,605 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	203,798,767 - 203,801,343 (-)	Ensembl	panpan1.1		panPan2

TLR5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	23,700,323 - 23,705,628 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	23,702,033 - 23,705,314 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	23,729,352 - 23,731,928 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	23,873,004 - 23,878,847 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	23,874,719 - 23,878,000 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	23,620,126 - 23,622,702 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	24,170,412 - 24,172,988 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	24,572,699 - 24,575,275 (+)	NCBI		UU_Cfam_GSD_1.0

TLR5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	19,387,666 - 19,410,024 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	19,387,666 - 19,410,024 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	21,886,309 - 21,888,880 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TLR5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	6,418,895 - 6,440,433 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	6,437,638 - 6,440,211 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	6,652,060 - 6,685,032 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tlr5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	5,500,461 - 5,503,034 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	5,495,723 - 5,503,462 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_021727158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040277658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000026274 ⟹ ENSSTOP00000016233

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936526	383,418 - 401,552 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000040103 ⟹ ENSSTOP00000029755

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936526	383,418 - 401,552 (-)	Ensembl

RefSeq Acc Id:

XM_021727158 ⟹ XP_021582833

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	54,356,858 - 54,363,906 (+)	NCBI
SpeTri2.0	NW_004936526	383,490 - 387,007 (-)	NCBI

Sequence:

show sequence

CTTTTTCCCCATAGGATCATGGCAGATCACCTTGACCTTCTCTTAGGAGTGTTGCTCATGGTGAGTCCTGTGTTCGGAATCCCTTCCTGCTCCTCTGATGGTGGGACAGCCTTATTTCGTTTCTGCAA
TCTCACCGAGATTCCCCCGGTCCTCAACACCACAGAGAAGCTCCTGCTAAGCTTCAACTACATCAGGACAGTCACTGCCACGTCCTTCCCCCTCCTAGAGCAGCTCCTACTGCTAGAGATGGGGAGCC
AGTTTACTCCCTTGTCTATCGACAAAGAGGCCTTCAGAAACCTGCCCAATCTTCGGATCTTGGATCTGGGTAAAAGTCAGATCGGCTTCTTGCATCCAGATGCTTTCCAGGGACTGTTCCATCTCTTT
GAACTGAGACTGTTTGCCTGTGGTCTCTCTAATGTGGTACTACGAGATGGTTATTTCAGAAATTTAACTTCTTTAATTCGCTTAGACCTGTCCTCTAATCAAATTGGGAGCCTTTACCTTCATCCTTC
GTTTCGGGAGCTGAATTCCTTAAAGTCCATAGATTTTTCCTTCAACCAGATATCCATCTTATGTGAAGAGGAGCTCAAGCCACTCCAAGGGAAAATGCTGTCTCTTTTCAAACTCAAATCAACTTACC
TGTACATCAGAGTCTCTGTGGACTGGGAGAAATGCATGAACCCATTCAGAAATATACAGCTAGAGACCCTTGATGTTTCTAATAACGGCTGGACTGTGGCTATCACGGGGAACTTCAGCAACGCCATC
AGGGGAAGCCAGATTTCCTCTTTGATTCTCACCTACCATATTATGGGTTCTGGGTTTGGCTTCCAAAACCTCAAAGACCCCGACGAGAACATATTTACCGGCCTGGAGAGAAGCTCAGTAGAGCGCCT
GGATCTGTCCCACGGGTACATCTTCTCCTTGAACCCCCGACTCTTTAAGACACTCAAGGACTTGAAAGTTCTGAACCTTTCCCACAACAAGATAAACAGGATTGCGGAGAAAGCCTTTTATGGACTTG
AGAACCTCCAGATACTCAATATATCGTATAACCTTCTGGGGGAACTTTATAATTCCAACTTCGAGGGGCTACGTAGCGTAGCCTACATTGACCTCCAAAAGAATCACATTGGAATAATTCAGGACCAG
ACCTTCAGATTCCTAAAAGAATTGCATACCTTAGATCTCAGGGACAACGCTCTTAAAACCATTTCTTTTATTCCAGACTTACTTACCGTCTTCTTAGGCGGCAACAAACTGGTGACTTTGCCCAACGT
GAACTTTAAAGCCAACTTCATCCACTTATCAGAGAACAAGCTAGAAAATCTGGCTGACCTCTACGAACTTCTCCGGGTATCTCAGCTCCAAACTCTCATTTTAAATCAAAATCGCTTTTCCTCTTGCA
GCCCAAGCCACGCCCCTTCGGGGAATCCCAACTTAAAACACCTTTTCCTTGGAGAAAATATGTTGCAACTTGTCTGGGAAACTGGGTTCTGCTGGGACGTTTTTAAGGGGCTCTCCCAACTCCAGGTT
CTGTATCTGAATAATAACTATCTTAATTTCCTTCCCCCTGGAGTATTTAGCGATCTGACGGCATTGAGGGGACTGAGCCTCAACTCCAACAGGCTGACGATTCTCCCTCCTGGCAGTTTACCTGCTAA
TTTAGAGATCCTGGATATATCCAGAAACCATCTCCTGTCTCCTGATCCTGGTTTATTTGCATCCCTTAGCATGTTGGACATAACTCATAACGAGTTCATCTGTGAGTGTGAACTCCGCACCTTTATCA
GTTGGCTCAATCAAACCAACGTCACTCTGTTGGGATCTCCTGCAGACATCTACTGCATGTATCCTAACTCGCTCTTAGGGGTTTCCCTCTACTCCGTTTCCATGGAAGACTGCGATGAAGAGGAAGTC
TTCAAGTCCCTAAAGTTTTCTCTTTACATCTTATTCATTGTCACTTTGACTCTGTTCCTCATGAGTGTTCTCATAGTCGCAAAGTTCCGGGGATTTTGTTTCATCTGTTACAAGACAGCCCAGAGATT
GCTGTTCCATGACCGTCCGCAGAGAAGAGAATCTGATAGGTACAGATACGACGCCTATTTATGCTTCAGTAGCAAAGACTTTGAGTGGGTACAGAATGCTTTGCTTAAACACCTGGACACTCAGTACA
GTGACCGAAATAGGTTTCACCTGTGCTTTGAAGAAAGAGACTTCGTCCCCGGGGAAAACCACATCACCAACATCCAAGCTGCCATCTGGAGCAGCCGGAAGATCGTCTGTCTTGTGAGCAGACACTTC
CTTAGGGATGGGTGGTGCCTGGAAGCCTTCAGTTACGCCCAGACCAGGTGCCTCTCTGACCTCAGCAGTGTCCTCATCATGGTGGTGGTTGGGTCCCTGTCCCAGTACCAGTTGATGAAACACCAGTC
AATCAGAGGATTCATACAGAAGCAGCAGTACTTGAGGTGGCCAGAAGATCTCCAAGACGTGGGCTGGTTTCTCAATAAACTCTCTCAGTGCATCCTAAAGAAAGAAAAAGGAAAGAAAGAAGACAGTC
GCATTCAGTTGCGATCCATAGCAACCGTCTCCTAGTCCAAAGAACAGCTTGCAATTCACCCCAAGCCATAAGGAACGCTTGACTTTGTATTTGCACAAAGTGGCCATTTGGGGGCTCTTTCTGGAGGT
CTTGTTCCTACTATAAAAACATCAGTCTCTTGGCTTTCATGTCAACATGATGTTTGTCTCACTGACCTCCAAGTGGAAAATAATATCTGGAAAATTGCAACTGCCCCTAGAGGTTCCCACTCACCATT
GATTTCCTTTCGGACCCAATAATACTGTTCTCTCCTGTTGTATGGACTACAGAATGTCCCCTAGTCATGGAAAGGGCACCTTGGAAAAAGTTACAGGTGGCTTCATGGTTTCGCAGTGTTCCGTTCAA
GAATGGTCTTGTCTGTGATTCTGATAAGTCTGTGTTCTGCAGAACAATACTAAGTAGAACTGAAACCTCTTTCCTTCTTTGGCTTTAGGAACATCAACAGTGCTGGATGCAGGTCACATTTTTATCTT
GGGGATAAAAGGTGGTCCCAAGGAACCTTCAACTCCTCTGAGTCTAACCCTTGTGGACCATGCCGTTTTGCATGTGACTCTTCTTTCAGCCTGATGCTCAGGACCTACCATGTTAGCACCAACCTACC
TCTTGAACTTCCCTTCCTGCCAGTAACACCTCATTCATCAACTCTGTAGGCTGTTGTAGGAAGAATATGGGCTTTATACACAGATCCTGGATCAAATTTTGATTCTGCTGCTTGTTAGTTGGGTCACT
TTGAGTATGGTACACCCTTGCTGGGCCTGCTTTCTTGCCTGTGGACATCACAGTTACTAGGAAAATTATATTGGTCAAGAATGTCAGGACTTCTCAGATCTTTTCCTTGGCTTTCCTTATGGCCACAA
GAGATGAAACACACTGAATGGCCTCTGGGGGCAGTTGCAGTGTCTTTGAATTTGTAATTTTT

hide sequence

RefSeq Acc Id:

XM_040277656 ⟹ XP_040133590

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	54,334,832 - 54,363,906 (+)	NCBI

RefSeq Acc Id:

XM_040277657 ⟹ XP_040133591

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	54,334,832 - 54,363,906 (+)	NCBI

RefSeq Acc Id:

XM_040277658 ⟹ XP_040133592

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	54,356,859 - 54,363,906 (+)	NCBI


Protein RefSeqs	XP_021582833	(Get FASTA)	NCBI Sequence Viewer
	XP_040133590	(Get FASTA)	NCBI Sequence Viewer
	XP_040133591	(Get FASTA)	NCBI Sequence Viewer
	XP_040133592	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000016233.2
	ENSSTOP00000029755.1
GenBank Protein	KAG3258034	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_021582833 ⟸ XM_021727158
- Peptide Label:	isoform X2
- UniProtKB:	A0A287D879 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADHLDLLLGVLLMVSPVFGIPSCSSDGGTALFRFCNLTEIPPVLNTTEKLLLSFNYIRTVTATSFPLLEQLLLLEMGSQFTPLSIDKEAFRNLPNLRILDLGKSQIGFLHPDAFQGLFHLFELRLFA CGLSNVVLRDGYFRNLTSLIRLDLSSNQIGSLYLHPSFRELNSLKSIDFSFNQISILCEEELKPLQGKMLSLFKLKSTYLYIRVSVDWEKCMNPFRNIQLETLDVSNNGWTVAITGNFSNAIRGSQIS SLILTYHIMGSGFGFQNLKDPDENIFTGLERSSVERLDLSHGYIFSLNPRLFKTLKDLKVLNLSHNKINRIAEKAFYGLENLQILNISYNLLGELYNSNFEGLRSVAYIDLQKNHIGIIQDQTFRFLK ELHTLDLRDNALKTISFIPDLLTVFLGGNKLVTLPNVNFKANFIHLSENKLENLADLYELLRVSQLQTLILNQNRFSSCSPSHAPSGNPNLKHLFLGENMLQLVWETGFCWDVFKGLSQLQVLYLNNN YLNFLPPGVFSDLTALRGLSLNSNRLTILPPGSLPANLEILDISRNHLLSPDPGLFASLSMLDITHNEFICECELRTFISWLNQTNVTLLGSPADIYCMYPNSLLGVSLYSVSMEDCDEEEVFKSLKF SLYILFIVTLTLFLMSVLIVAKFRGFCFICYKTAQRLLFHDRPQRRESDRYRYDAYLCFSSKDFEWVQNALLKHLDTQYSDRNRFHLCFEERDFVPGENHITNIQAAIWSSRKIVCLVSRHFLRDGWC LEAFSYAQTRCLSDLSSVLIMVVVGSLSQYQLMKHQSIRGFIQKQQYLRWPEDLQDVGWFLNKLSQCILKKEKGKKEDSRIQLRSIATVS hide sequence

RefSeq Acc Id:	XP_040133590 ⟸ XM_040277656
- Peptide Label:	isoform X1
- UniProtKB:	I3MVT8 (UniProtKB/TrEMBL), A0A287D879 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040133591 ⟸ XM_040277657
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_040133592 ⟸ XM_040277658
- Peptide Label:	isoform X4

Ensembl Acc Id:

ENSSTOP00000029755 ⟸ ENSSTOT00000040103

Protein Domains

TIR

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000022418	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000026274.2	UniProtKB/TrEMBL
	ENSSTOT00000040103.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.10140	UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
InterPro	Cys-rich_flank_reg_C	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
	TIR_dom	UniProtKB/TrEMBL
	Toll-like_receptor	UniProtKB/TrEMBL
	Toll_tir_struct_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Tlr5	ENTREZGENE
PANTHER	PTHR24365	UniProtKB/TrEMBL
	PTHR24365:SF525	UniProtKB/TrEMBL
Pfam	LRR_1	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
	TIR	UniProtKB/TrEMBL
PIRSF	Toll-like_receptor	UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/TrEMBL
	TIR	UniProtKB/TrEMBL
SMART	LRR_SD22	UniProtKB/TrEMBL
	LRR_TYP	UniProtKB/TrEMBL
	LRRCT	UniProtKB/TrEMBL
	TIR	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
	SSF52200	UniProtKB/TrEMBL
UniProt	A0A287D879	ENTREZGENE, UniProtKB/TrEMBL
	I3MVT8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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