Ddx21 (DExD-box helicase 21) - Rat Genome Database

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Gene: Ddx21 (DExD-box helicase 21) Rattus norvegicus
Analyze
Symbol: Ddx21
Name: DExD-box helicase 21
RGD ID: 1307306
Description: Predicted to enable RNA binding activity; RNA helicase activity; and identical protein binding activity. Predicted to be involved in several processes, including R-loop processing; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of macromolecule biosynthetic process. Predicted to act upstream of or within response to exogenous dsRNA and response to virus. Predicted to be located in chromosome; cytosol; and nucleoplasm. Predicted to be part of B-WICH complex. Predicted to be active in nucleolus. Orthologous to human DDX21 (DExD-box helicase 21); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ddx21a; Ddx21b; DEAD (Asp-Glu-Ala-Asp) box helicase 21; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b; DEAD box protein 21; DEAD-box helicase 21; gu-alpha; LOC317399; LOC361847; MGC112658; MGC124980; nucleolar RNA helicase 2; nucleolar RNA helicase Gu; nucleolar RNA helicase II; RH II/Gu
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Ddx21-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82031,077,044 - 31,097,238 (-)NCBIGRCr8
mRatBN7.22030,534,319 - 30,554,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,534,319 - 30,554,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,545,279 - 31,565,477 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,936,186 - 30,956,386 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,673,000 - 31,693,177 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,213,147 - 32,232,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,213,148 - 32,232,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02033,997,711 - 34,017,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,838,671 - 29,860,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2031,953,138 - 31,973,565 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 153 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddx21Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DDX21 mRNA]CTDPMID:31150632
Ddx21Rat1,2-dimethylhydrazine increases expressionISODdx21 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of DDX21 mRNACTDPMID:22206623
Ddx21Rat17beta-estradiol affects expressionISODdx21 (Mus musculus)6480464Estradiol affects the expression of DDX21 mRNACTDPMID:15598610
Ddx21Rat17beta-estradiol increases expressionISODDX21 (Homo sapiens)6480464Estradiol results in increased expression of DDX21 mRNACTDPMID:16514628 more ...
Ddx21Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISODdx21 (Mus musculus)64804642 more ...CTDPMID:30294300
Ddx21Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODdx21 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DDX21 mRNACTDPMID:21570461
Ddx21Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISODDX21 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of DDX21 mRNACTDPMID:18061397 and PMID:22903824
Ddx21Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISODDX21 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of DDX21 mRNACTDPMID:20106945 and PMID:21632981
Ddx21Rat2,4,6-tribromophenol decreases expressionISODDX21 (Homo sapiens)64804642 more ...CTDPMID:31675489
Ddx21Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of DDX21 mRNACTDPMID:21346803
Ddx21Rat2,6-dimethoxyphenol multiple interactionsISODDX21 (Homo sapiens)6480464[pyrogallol 1 more ...CTDPMID:38598786
Ddx21Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of DDX21 mRNACTDPMID:21346803
Ddx21Rat2-nitrofluorene increases expressionEXP 64804642-nitrofluorene results in increased expression of DDX21 mRNACTDPMID:15890375
Ddx21Rat3',5'-cyclic UMP affects bindingISODDX21 (Homo sapiens)6480464DDX21 protein binds to cyclic 3' and 5'-uridine monophosphateCTDPMID:30528433
Ddx21Rat3,3',5,5'-tetrabromobisphenol A increases expressionISODDX21 (Homo sapiens)6480464tetrabromobisphenol A results in increased expression of DDX21 proteinCTDPMID:31675489
Ddx21Rat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of DDX21 mRNACTDPMID:19162173
Ddx21Rat4,4'-sulfonyldiphenol increases expressionISODdx21 (Mus musculus)6480464bisphenol S results in increased expression of DDX21 mRNACTDPMID:39298647
Ddx21Rat4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expressionEXP 64804644-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DDX21 mRNACTDPMID:15890375
Ddx21Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2 and 6-dinitrotoluene affects the expression of DDX21 mRNACTDPMID:21346803
Ddx21Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of DDX21 mRNACTDPMID:30047161

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Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddx21Ratdefense response to virus involved_inIEAUniProtKB-KW:KW-00511600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratinnate immune response involved_inIEAUniProtKB-KW:KW-03991600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratpositive regulation of canonical NF-kappaB signal transduction involved_inISSUniProtKB:Q9JIK51600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21Ratpositive regulation of canonical NF-kappaB signal transduction involved_inIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratpositive regulation of canonical NF-kappaB signal transduction involved_inISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratpositive regulation of myeloid dendritic cell cytokine production involved_inISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratpositive regulation of myeloid dendritic cell cytokine production involved_inIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratpositive regulation of transcription by RNA polymerase III involved_inISODDX21 (Homo sapiens)1624291 PMID:16603771RGDPMID:16603771
Ddx21Ratpositive regulation of transcription by RNA polymerase III involved_inIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21RatR-loop processing involved_inISSUniProtKB:Q9NR301600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21RatR-loop processing involved_inIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21RatR-loop processing involved_inISODDX21 (Homo sapiens)1624291 PMID:28790157RGDPMID:28790157
Ddx21Ratresponse to exogenous dsRNA acts_upstream_of_or_withinISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratresponse to exogenous dsRNA acts_upstream_of_or_withinIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratresponse to virus acts_upstream_of_or_withinISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratresponse to virus acts_upstream_of_or_withinIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21RatrRNA processing involved_inIEAUniProtKB-KW:KW-06981600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Rattranscription by RNA polymerase II involved_inISSUniProtKB:Q9NR301600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21Rattranscription by RNA polymerase II involved_inIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 20 of 23 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddx21RatB-WICH complex part_ofISODDX21 (Homo sapiens)1624291 PMID:16603771RGDPMID:16603771
Ddx21RatB-WICH complex part_ofIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratchromosome located_inISODDX21 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Ddx21Ratchromosome located_inIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratcytosol located_inISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratcytosol located_inIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratcytosol located_inISSUniProtKB:Q9JIK51600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Ddx21Ratmitochondrion located_inIEAUniProtKB-SubCell:SL-01731600115GO_REF:0000044UniProtGO_REF:0000044
Ddx21Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratnucleolus located_inISODDX21 (Homo sapiens)1624291 PMID:28790157RGDPMID:28790157
Ddx21Ratnucleolus located_inIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Ratnucleolus located_inIEAUniProtKB-SubCell:SL-01881600115GO_REF:0000044UniProtGO_REF:0000044
Ddx21Ratnucleolus is_active_inIBAPANTHER:PTN002777480 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ddx21Ratnucleolus located_inISSUniProtKB:Q9NR301600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21Ratnucleolus located_inISODDX21 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Ddx21Ratnucleoplasm located_inISSUniProtKB:Q9NR301600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21Ratnucleoplasm located_inIEAUniProtKB-SubCell:SL-01901600115GO_REF:0000044UniProtGO_REF:0000044
Ddx21Ratnucleoplasm located_inIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 23 rows

Molecular Function
1 to 20 of 34 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddx21Rat7SK snRNA binding enablesISSUniProtKB:Q9NR301600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21Rat7SK snRNA binding enablesIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Rat7SK snRNA binding enablesISODDX21 (Homo sapiens)1624291 PMID:25470060RGDPMID:25470060
Ddx21RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21RatATP binding enablesIEAInterPro:IPR011545 and InterPro:IPR0125621600115GO_REF:0000002InterProGO_REF:0000002
Ddx21RatATP hydrolysis activity enablesIEARHEA:130651600115GO_REF:0000116RHEAGO_REF:0000116
Ddx21Ratdouble-stranded RNA binding enablesISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratdouble-stranded RNA binding enablesIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21Rathelicase activity enablesIEAUniProtKB-KW:KW-03471600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Rathelicase activity enablesIEAInterPro:IPR0125621600115GO_REF:0000002InterProGO_REF:0000002
Ddx21Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratidentical protein binding enablesISODdx21 (Mus musculus)1624291 PMID:21703541RGDPMID:21703541
Ddx21Ratidentical protein binding enablesIEAUniProtKB:Q9JIK5 and ensembl:ENSMUSP000000426911600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21RatmiRNA binding enablesISODDX21 (Homo sapiens)1624291 PMID:28431233RGDPMID:28431233
Ddx21RatmiRNA binding enablesIEAUniProtKB:Q9NR30 and ensembl:ENSP000003461201600115GO_REF:0000107EnsemblGO_REF:0000107
Ddx21RatmiRNA binding enablesISSUniProtKB:Q9NR301600115GO_REF:0000024UniProtGO_REF:0000024
Ddx21RatmRNA binding enablesIBAFB:FBgn0283442 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ddx21Ratnucleic acid binding enablesIEAInterPro:IPR011545 and InterPro:IPR0359791600115GO_REF:0000002InterProGO_REF:0000002
Ddx21Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Ddx21Ratprotein binding enablesISODdx21 (Mus musculus)1624291PR:Q8VHK9 more ...RGDPMID:21703541 and PMID:31128943
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:1639225   PMID:9461305   PMID:12477932   PMID:15489334   PMID:16210410   PMID:19946888   PMID:21703541   PMID:22658674   PMID:22681889   PMID:25470060   PMID:28431233   PMID:28790157  
PMID:33450132  



Ddx21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82031,077,044 - 31,097,238 (-)NCBIGRCr8
mRatBN7.22030,534,319 - 30,554,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,534,319 - 30,554,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,545,279 - 31,565,477 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,936,186 - 30,956,386 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,673,000 - 31,693,177 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,213,147 - 32,232,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,213,148 - 32,232,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02033,997,711 - 34,017,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,838,671 - 29,860,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2031,953,138 - 31,973,565 (-)NCBICelera
Cytogenetic Map20q11NCBI
DDX21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381068,956,170 - 68,985,068 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1068,956,135 - 68,985,068 (+)EnsemblGRCh38hg38GRCh38
GRCh371070,715,926 - 70,744,824 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361070,385,898 - 70,414,285 (+)NCBINCBI36Build 36hg18NCBI36
Build 341070,385,897 - 70,414,285NCBI
Celera1063,991,762 - 64,020,150 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1064,717,792 - 64,746,685 (+)NCBIHuRef
CHM1_11070,997,606 - 71,026,553 (+)NCBICHM1_1
T2T-CHM13v2.01069,825,602 - 69,854,499 (+)NCBIT2T-CHM13v2.0
Ddx21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,416,026 - 62,438,077 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,416,030 - 62,438,060 (-)EnsemblGRCm39 Ensembl
GRCm381062,580,247 - 62,602,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,580,251 - 62,602,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv371062,042,995 - 62,065,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361061,975,604 - 61,997,655 (-)NCBIMGSCv36mm8
Celera1063,683,725 - 63,705,771 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.43NCBI
Ddx21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543722,050,937 - 22,071,118 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543722,050,029 - 22,071,213 (-)NCBIChiLan1.0ChiLan1.0
DDX21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2881,102,441 - 81,131,439 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11081,098,619 - 81,136,760 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01065,423,319 - 65,452,266 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11067,956,857 - 67,985,867 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1067,956,857 - 67,985,867 (+)Ensemblpanpan1.1panPan2
DDX21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1420,109,719 - 20,134,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl420,109,778 - 20,132,338 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha420,240,134 - 20,264,990 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0420,381,832 - 20,407,325 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl420,381,870 - 20,407,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1420,282,539 - 20,307,462 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0420,485,654 - 20,510,665 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,828,776 - 20,854,073 (+)NCBIUU_Cfam_GSD_1.0
Ddx21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721360,933,799 - 60,956,220 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365219,429,015 - 9,448,890 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365219,426,544 - 9,448,973 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1472,039,982 - 72,063,773 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11472,039,985 - 72,063,778 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,054,874 - 78,078,395 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,339,614 - 62,370,032 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604823,081,720 - 23,112,357 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,179,662 - 3,203,536 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247543,180,501 - 3,203,449 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ddx21
32 total Variants

Predicted Target Of
Summary Value
Count of predictions:901
Count of miRNA genes:320
Interacting mature miRNAs:429
Transcripts:ENSRNOT00000068184
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat

1 to 10 of 16 rows
BI302095  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,554,669 - 30,554,822 (+)MAPPERmRatBN7.2
Rnor_6.02032,232,789 - 32,232,941NCBIRnor6.0
Rnor_5.02034,017,353 - 34,017,505UniSTSRnor5.0
RGSC_v3.42029,860,671 - 29,860,823UniSTSRGSC3.4
Celera2031,973,722 - 31,973,874UniSTS
RH 3.4 Map20308.38UniSTS
Cytogenetic Map20q11UniSTS
RH129516  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20q11UniSTS
RH133206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,535,678 - 30,535,859 (+)MAPPERmRatBN7.2
mRatBN7.2X18,566,044 - 18,566,225 (+)MAPPERmRatBN7.2
Rnor_6.0X19,383,535 - 19,383,715NCBIRnor6.0
Rnor_6.02032,214,507 - 32,214,687NCBIRnor6.0
Rnor_5.02033,999,071 - 33,999,251UniSTSRnor5.0
Rnor_5.0X20,150,411 - 20,150,591UniSTSRnor5.0
RGSC_v3.4X38,742,330 - 38,742,510UniSTSRGSC3.4
RGSC_v3.42029,840,031 - 29,840,211UniSTSRGSC3.4
Celera2031,954,498 - 31,954,678UniSTS
CeleraX18,831,612 - 18,831,792UniSTS
Cytogenetic Map20q11UniSTS
RH144150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22030,547,722 - 30,547,884 (+)MAPPERmRatBN7.2
Rnor_6.02032,225,948 - 32,226,109NCBIRnor6.0
Rnor_5.02034,010,512 - 34,010,673UniSTSRnor5.0
RGSC_v3.42029,852,037 - 29,852,198UniSTSRGSC3.4
Celera2031,966,539 - 31,966,700UniSTS
RH 3.4 Map20308.36UniSTS
Cytogenetic Map20q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000068184   ⟹   ENSRNOP00000063494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2030,534,319 - 30,554,543 (-)Ensembl
Rnor_6.0 Ensembl2032,213,148 - 32,232,632 (-)Ensembl
RefSeq Acc Id: NM_001037201   ⟹   NP_001032278
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82031,077,044 - 31,097,238 (-)NCBI
mRatBN7.22030,534,319 - 30,554,513 (-)NCBI
Rnor_6.02032,213,147 - 32,232,632 (-)NCBI
Rnor_5.02033,997,711 - 34,017,196 (-)NCBI
RGSC_v3.42029,838,671 - 29,860,514 (-)RGD
Celera2031,953,138 - 31,973,565 (-)RGD
Sequence:
Protein RefSeqs NP_001032278 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI05879 (Get FASTA)   NCBI Sequence Viewer  
  EDL92965 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063494
  ENSRNOP00000063494.1
GenBank Protein Q3B8Q1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001032278   ⟸   NM_001037201
- UniProtKB: Q3B8Q1 (UniProtKB/Swiss-Prot),   A6K457 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063494   ⟸   ENSRNOT00000068184
Name Modeler Protein Id AA Range Protein Structure
AF-Q3B8Q1-F1-model_v2 AlphaFold Q3B8Q1 1-782 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701616
Promoter ID:EPDNEW_R12140
Type:multiple initiation site
Name:Ddx21_1
Description:DExD-box helicase 21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02032,232,644 - 32,232,704EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-3684 BioCyc
Ensembl Genes ENSRNOG00000043099 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000068184 ENTREZGENE
  ENSRNOT00000068184.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.2280 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126328 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DEAD_box_RNA_helicases UniProtKB/Swiss-Prot
  GUCT UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
KEGG Report rno:317399 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124980 IMAGE-MGC_LOAD
NCBI Gene 317399 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DEAD UniProtKB/Swiss-Prot
  DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  GUCT UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
PhenoGen Ddx21 PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
  Q_MOTIF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000043099 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
  SSF54928 UniProtKB/Swiss-Prot
UniProt A6K457 ENTREZGENE, UniProtKB/TrEMBL
  DDX21_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Ddx21  DExD-box helicase 21  Ddx21  DEAD-box helicase 21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Ddx21  DEAD-box helicase 21  Ddx21  DEAD (Asp-Glu-Ala-Asp) box helicase 21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-04 Ddx21  DEAD (Asp-Glu-Ala-Asp) box helicase 21  Ddx21b  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b  Data merged from RGD:1304998 737654 APPROVED
2012-07-16 Ddx21  DEAD (Asp-Glu-Ala-Asp) box helicase 21  Ddx21  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Ddx21  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21  Ddx21a  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ddx21b  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b  Ddx21b_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b (predicted)  Symbol and Name updated 1559027 APPROVED
2005-12-06 Ddx21a  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a  Ddx21a_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ddx21a_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a (predicted)      Symbol and Name status set to approved 70820 APPROVED
2005-01-12 Ddx21b_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 21b (predicted)      Symbol and Name status set to approved 70820 APPROVED