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Gene: Ruvbl1 (RuvB-like AAA ATPase 1) Rattus norvegicus
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Symbol: Ruvbl1
Name: RuvB-like AAA ATPase 1
Description: Exhibits 3'-5' DNA helicase activity. Involved in positive regulation of plasminogen activation and regulation of fibroblast apoptotic process. Localizes to the nuclear matrix and protein-containing complex. Orthologous to human RUVBL1 (RuvB like AAA ATPase 1); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; Wnt signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; DNA helicase p50; NMP238; pontin 52; Pontin52; ruvB-like 1; RuvB-like 1 (E. coli); RuvB-like protein 1; Tip49a
Orthologs:
Homo sapiens (human) : RUVBL1 (RuvB like AAA ATPase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ruvbl1 (RuvB-like protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ruvbl1 (RuvB like AAA ATPase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RUVBL1 (RuvB like AAA ATPase 1)
Canis lupus familiaris (dog) : RUVBL1 (RuvB like AAA ATPase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ruvbl1 (RuvB like AAA ATPase 1)
Sus scrofa (pig) : RUVBL1 (RuvB like AAA ATPase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04120,411,917 - 120,447,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04185,651,851 - 185,687,385 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,556,857 - 122,591,769 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14122,801,337 - 122,836,249 (+)NCBI
Celera4109,888,321 - 109,923,233 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ruvbl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68373
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.