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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ruvbl1 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RUVBL1 mRNA] | CTD | PMID:31150632 | Ruvbl1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | RGD:68538 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RUVBL1 mRNA | CTD | PMID:36331819 | Ruvbl1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | RGD:68538 | 6480464 | 1,2-Dimethylhydrazine results in increased expression of RUVBL1 mRNA | CTD | PMID:22206623 | Ruvbl1 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of RUVBL1 mRNA | CTD | PMID:17557909 | Ruvbl1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | RGD:68538 | 6480464 | Ethinyl Estradiol affects the expression of RUVBL1 mRNA | CTD | PMID:17555576 | Ruvbl1 | Rat | 17beta-estradiol | increases expression | ISO | RGD:68537 | 6480464 | Estradiol results in increased expression of RUVBL1 mRNA | CTD | PMID:31614463 | Ruvbl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:68538 | 6480464 | Tetrachlorodibenzodioxin affects the expression of RUVBL1 mRNA | CTD | PMID:21570461 | Ruvbl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RUVBL1 mRNA | CTD | PMID:34747641 | Ruvbl1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of RUVBL1 mRNA | CTD | PMID:21346803 | Ruvbl1 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | RGD:68537 | 6480464 | [Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of and affects the more ... | CTD | PMID:38598786 | Ruvbl1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of RUVBL1 mRNA | CTD | PMID:21346803 | Ruvbl1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUVBL1 mRNA | CTD | PMID:23196670 | Ruvbl1 | Rat | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2,6-dinitrotoluene affects the expression of RUVBL1 mRNA | CTD | PMID:21346803 | Ruvbl1 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:68537 | 6480464 | Decitabine affects the expression of RUVBL1 mRNA | CTD | PMID:17145863 | Ruvbl1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of RUVBL1 mRNA | CTD | PMID:30047161 | Ruvbl1 | Rat | acrylamide | decreases expression | ISO | RGD:68537 | 6480464 | Acrylamide results in decreased expression of RUVBL1 mRNA | CTD | PMID:32763439 | Ruvbl1 | Rat | actinomycin D | multiple interactions | ISO | RGD:68537 | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of RUVBL1 protein | CTD | PMID:38460933 | Ruvbl1 | Rat | all-trans-retinoic acid | decreases expression | ISO | RGD:68537 | 6480464 | Tretinoin results in decreased expression of RUVBL1 mRNA; Tretinoin results in decreased expression of RUVBL1 more ... | CTD | PMID:17051635|PMID:33167477 | Ruvbl1 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of RUVBL1 mRNA | CTD | PMID:30047161 | Ruvbl1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RUVBL1 mRNA | CTD | PMID:16483693 | Ruvbl1 | Rat | antirheumatic drug | decreases expression | ISO | RGD:68537 | 6480464 | Antirheumatic Agents results in decreased expression of RUVBL1 mRNA | CTD | PMID:24449571 | Ruvbl1 | Rat | arsenite(3-) | multiple interactions | ISO | RGD:68537 | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RUVBL1 mRNA] | CTD | PMID:32406909 | Ruvbl1 | Rat | arsenous acid | multiple interactions | ISO | RGD:68537 | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RUVBL1 protein] | CTD | PMID:26598702 | Ruvbl1 | Rat | arsenous acid | increases expression | ISO | RGD:68537 | 6480464 | Arsenic Trioxide results in increased expression of RUVBL1 protein | CTD | PMID:19364129 | Ruvbl1 | Rat | azoxystrobin | increases expression | ISO | RGD:68537 | 6480464 | azoxystrobin results in increased expression of RUVBL1 mRNA | CTD | PMID:33512557 | Ruvbl1 | Rat | benzo[a]pyrene | decreases expression | ISO | RGD:68537 | 6480464 | Benzo(a)pyrene results in decreased expression of RUVBL1 mRNA; Benzo(a)pyrene results in decreased expression of RUVBL1 more ... | CTD | PMID:20064835|PMID:20097212 | Ruvbl1 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:68537 | 6480464 | [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of RUVBL1 more ... | CTD | PMID:33872906 | Ruvbl1 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:68538 | 6480464 | Diethylhexyl Phthalate results in increased expression of RUVBL1 mRNA | CTD | PMID:34319233 | Ruvbl1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RUVBL1 mRNA | CTD | PMID:25181051 | Ruvbl1 | Rat | bisphenol A | decreases expression | ISO | RGD:68537 | 6480464 | bisphenol A results in decreased expression of RUVBL1 protein | CTD | PMID:34186270 | Ruvbl1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RUVBL1 mRNA | CTD | PMID:30816183|PMID:33296240 | Ruvbl1 | Rat | bisphenol AF | increases expression | ISO | RGD:68537 | 6480464 | bisphenol AF results in increased expression of RUVBL1 protein | CTD | PMID:34186270 | Ruvbl1 | Rat | Bisphenol B | increases expression | ISO | RGD:68537 | 6480464 | bisphenol B results in increased expression of RUVBL1 protein | CTD | PMID:34186270 | Ruvbl1 | Rat | bisphenol F | increases expression | ISO | RGD:68537 | 6480464 | bisphenol F results in increased expression of RUVBL1 protein | CTD | PMID:34186270 | Ruvbl1 | Rat | bleomycin A5 | increases expression | ISO | RGD:68537 | 6480464 | bleomycetin results in increased expression of RUVBL1 mRNA | CTD | PMID:21040473 | Ruvbl1 | Rat | cadmium dichloride | decreases expression | ISO | RGD:68537 | 6480464 | Cadmium Chloride results in decreased expression of RUVBL1 mRNA | CTD | PMID:38568856 | Ruvbl1 | Rat | captan | increases expression | ISO | RGD:68538 | 6480464 | Captan results in increased expression of RUVBL1 mRNA | CTD | PMID:31558096 | Ruvbl1 | Rat | ceruletide | increases expression | EXP | | 6480464 | Ceruletide results in increased expression of RUVBL1 protein | CTD | PMID:18024178 | Ruvbl1 | Rat | chromium(6+) | affects expression | ISO | RGD:68538 | 6480464 | chromium hexavalent ion affects the expression of RUVBL1 mRNA | CTD | PMID:28472532 | Ruvbl1 | Rat | cobalt dichloride | multiple interactions | ISO | RGD:68537 | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RUVBL1 mRNA] | CTD | PMID:22202117 | Ruvbl1 | Rat | cobalt dichloride | decreases expression | ISO | RGD:68537 | 6480464 | cobaltous chloride results in decreased expression of RUVBL1 mRNA | CTD | PMID:19320972|PMID:19376846|PMID:22202117 | Ruvbl1 | Rat | copper atom | multiple interactions | ISO | RGD:68537 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RUVBL1 mRNA | CTD | PMID:20971185 | Ruvbl1 | Rat | copper(0) | multiple interactions | ISO | RGD:68537 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RUVBL1 mRNA | CTD | PMID:20971185 | Ruvbl1 | Rat | copper(II) sulfate | decreases expression | ISO | RGD:68537 | 6480464 | Copper Sulfate results in decreased expression of RUVBL1 mRNA | CTD | PMID:19549813 | Ruvbl1 | Rat | cyclosporin A | decreases expression | ISO | RGD:68537 | 6480464 | Cyclosporine results in decreased expression of RUVBL1 mRNA | CTD | PMID:25562108 | Ruvbl1 | Rat | DDE | increases expression | ISO | RGD:68537 | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of RUVBL1 mRNA | CTD | PMID:38568856 | Ruvbl1 | Rat | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of RUVBL1 mRNA | CTD | PMID:23640034 | Ruvbl1 | Rat | diarsenic trioxide | multiple interactions | ISO | RGD:68537 | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to RUVBL1 protein] | CTD | PMID:26598702 | Ruvbl1 | Rat | diarsenic trioxide | increases expression | ISO | RGD:68537 | 6480464 | Arsenic Trioxide results in increased expression of RUVBL1 protein | CTD | PMID:19364129 | Ruvbl1 | Rat | Dibutyl phosphate | affects expression | ISO | RGD:68537 | 6480464 | di-n-butylphosphoric acid affects the expression of RUVBL1 mRNA | CTD | PMID:37042841 | Ruvbl1 | Rat | dibutyl phthalate | decreases expression | ISO | RGD:68538 | 6480464 | Dibutyl Phthalate results in decreased expression of RUVBL1 mRNA | CTD | PMID:17361019 | Ruvbl1 | Rat | disodium selenite | increases expression | ISO | RGD:68537 | 6480464 | Sodium Selenite results in increased expression of RUVBL1 mRNA | CTD | PMID:18175754 | Ruvbl1 | Rat | dopamine | increases expression | ISO | RGD:68537 | 6480464 | Dopamine results in increased expression of RUVBL1 protein | CTD | PMID:24675778 | Ruvbl1 | Rat | doxorubicin | increases expression | ISO | RGD:68537 | 6480464 | Doxorubicin results in increased expression of RUVBL1 mRNA | CTD | PMID:29803840 | Ruvbl1 | Rat | elemental selenium | increases expression | ISO | RGD:68537 | 6480464 | Selenium results in increased expression of RUVBL1 mRNA | CTD | PMID:19244175 | Ruvbl1 | Rat | enzyme inhibitor | multiple interactions | ISO | RGD:68537 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Ruvbl1 | Rat | epoxiconazole | decreases expression | ISO | RGD:68538 | 6480464 | epoxiconazole results in decreased expression of RUVBL1 mRNA | CTD | PMID:35436446 | Ruvbl1 | Rat | ethyl methanesulfonate | decreases expression | ISO | RGD:68537 | 6480464 | Ethyl Methanesulfonate results in decreased expression of RUVBL1 mRNA | CTD | PMID:23649840 | Ruvbl1 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of RUVBL1 mRNA | CTD | PMID:24136188 | Ruvbl1 | Rat | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of RUVBL1 mRNA | CTD | PMID:18035473 | Ruvbl1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of RUVBL1 mRNA | CTD | PMID:24136188 | Ruvbl1 | Rat | furfural | multiple interactions | ISO | RGD:68537 | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of more ... | CTD | PMID:38598786 | Ruvbl1 | Rat | geraniol | decreases expression | ISO | RGD:68537 | 6480464 | geraniol results in decreased expression of RUVBL1 mRNA | CTD | PMID:27683099 | Ruvbl1 | Rat | glyphosate | decreases expression | ISO | RGD:68537 | 6480464 | Glyphosate results in decreased expression of RUVBL1 mRNA | CTD | PMID:31295307 | Ruvbl1 | Rat | glyphosate | increases expression | ISO | RGD:68538 | 6480464 | Glyphosate results in increased expression of RUVBL1 protein | CTD | PMID:37208198 | Ruvbl1 | Rat | GSK-J4 | decreases expression | ISO | RGD:68537 | 6480464 | GSK-J4 results in decreased expression of RUVBL1 mRNA | CTD | PMID:29301935 | Ruvbl1 | Rat | ivermectin | decreases expression | ISO | RGD:68537 | 6480464 | Ivermectin results in decreased expression of RUVBL1 protein | CTD | PMID:32959892 | Ruvbl1 | Rat | methidathion | increases expression | ISO | RGD:68538 | 6480464 | methidathion results in increased expression of RUVBL1 mRNA | CTD | PMID:34813904 | Ruvbl1 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of RUVBL1 mRNA | CTD | PMID:30047161 | Ruvbl1 | Rat | methyl methanesulfonate | decreases expression | ISO | RGD:68537 | 6480464 | Methyl Methanesulfonate results in decreased expression of RUVBL1 mRNA | CTD | PMID:23649840 | Ruvbl1 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:68537 | 6480464 | [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of RUVBL1 more ... | CTD | PMID:33872906 | Ruvbl1 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | RGD:68537 | 6480464 | Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 more ... | CTD | PMID:26921499 | Ruvbl1 | Rat | nickel atom | increases expression | ISO | RGD:68537 | 6480464 | Nickel results in increased expression of RUVBL1 mRNA | CTD | PMID:24768652|PMID:25583101 | Ruvbl1 | Rat | nitrates | multiple interactions | ISO | RGD:68538 | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of RUVBL1 more ... | CTD | PMID:35964746 | Ruvbl1 | Rat | Nutlin-3 | multiple interactions | ISO | RGD:68537 | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of RUVBL1 protein | CTD | PMID:38460933 | Ruvbl1 | Rat | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of RUVBL1 mRNA | CTD | PMID:23358140 | Ruvbl1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RUVBL1 mRNA | CTD | PMID:25729387 | Ruvbl1 | Rat | ozone | multiple interactions | ISO | RGD:68538 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Ruvbl1 | Rat | ozone | multiple interactions | ISO | RGD:68537 | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of RUVBL1 mRNA | CTD | PMID:35430440 | Ruvbl1 | Rat | paracetamol | affects expression | ISO | RGD:68538 | 6480464 | Acetaminophen affects the expression of RUVBL1 mRNA | CTD | PMID:17562736 | Ruvbl1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RUVBL1 mRNA | CTD | PMID:33387578 | Ruvbl1 | Rat | paracetamol | decreases expression | ISO | RGD:68537 | 6480464 | Acetaminophen results in decreased expression of RUVBL1 mRNA | CTD | PMID:21420995 | Ruvbl1 | Rat | pentachlorophenol | increases expression | ISO | RGD:68538 | 6480464 | Pentachlorophenol results in increased expression of RUVBL1 mRNA | CTD | PMID:23892564 | Ruvbl1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:68538 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RUVBL1 mRNA | CTD | PMID:36331819 | Ruvbl1 | Rat | pirinixic acid | multiple interactions | ISO | RGD:68538 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of RUVBL1 mRNA] | CTD | PMID:17950772 | Ruvbl1 | Rat | pirinixic acid | increases expression | ISO | RGD:68538 | 6480464 | pirinixic acid results in increased expression of RUVBL1 mRNA | CTD | PMID:17950772|PMID:23811191 | Ruvbl1 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of RUVBL1 mRNA | CTD | PMID:30047161 | Ruvbl1 | Rat | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of RUVBL1 mRNA | CTD | PMID:20726854 | Ruvbl1 | Rat | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of RUVBL1 mRNA | CTD | PMID:30047161 | Ruvbl1 | Rat | quercetin | increases expression | ISO | RGD:68537 | 6480464 | Quercetin results in increased expression of RUVBL1 protein | CTD | PMID:14750173 | Ruvbl1 | Rat | quercetin | decreases expression | ISO | RGD:68537 | 6480464 | Quercetin results in decreased expression of RUVBL1 mRNA | CTD | PMID:30152185 | Ruvbl1 | Rat | rotenone | increases expression | ISO | RGD:68537 | 6480464 | Rotenone results in increased expression of RUVBL1 mRNA | CTD | PMID:33512557 | Ruvbl1 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of RUVBL1 protein | CTD | PMID:35544339 | Ruvbl1 | Rat | selenium atom | increases expression | ISO | RGD:68537 | 6480464 | Selenium results in increased expression of RUVBL1 mRNA | CTD | PMID:19244175 | Ruvbl1 | Rat | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of RUVBL1 protein | CTD | PMID:29459688 | Ruvbl1 | Rat | sodium arsenite | affects expression | ISO | RGD:68537 | 6480464 | sodium arsenite affects the expression of RUVBL1 mRNA | CTD | PMID:34032870 | Ruvbl1 | Rat | sodium arsenite | decreases expression | ISO | RGD:68537 | 6480464 | sodium arsenite results in decreased expression of RUVBL1 mRNA | CTD | PMID:38568856 | Ruvbl1 | Rat | sodium chloride | multiple interactions | ISO | RGD:68537 | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of more ... | CTD | PMID:38598786 | Ruvbl1 | Rat | T-2 toxin | increases expression | ISO | RGD:68537 | 6480464 | T-2 Toxin results in increased expression of RUVBL1 mRNA | CTD | PMID:31863870|PMID:34581912 | Ruvbl1 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RUVBL1 mRNA] | CTD | PMID:31150632 | Ruvbl1 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of RUVBL1 mRNA | CTD | PMID:31150632 | Ruvbl1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RUVBL1 mRNA | CTD | PMID:23411599 | Ruvbl1 | Rat | thiram | decreases expression | ISO | RGD:68537 | 6480464 | Thiram results in decreased expression of RUVBL1 mRNA | CTD | PMID:38568856 | Ruvbl1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RUVBL1 mRNA | CTD | PMID:25729387 | Ruvbl1 | Rat | trimellitic anhydride | increases expression | ISO | RGD:68538 | 6480464 | trimellitic anhydride results in increased expression of RUVBL1 mRNA | CTD | PMID:19042947 | Ruvbl1 | Rat | triphenyl phosphate | affects expression | ISO | RGD:68537 | 6480464 | triphenyl phosphate affects the expression of RUVBL1 mRNA | CTD | PMID:37042841 | Ruvbl1 | Rat | urethane | decreases expression | ISO | RGD:68537 | 6480464 | Urethane results in decreased expression of RUVBL1 mRNA | CTD | PMID:28818685 | Ruvbl1 | Rat | valproic acid | affects expression | ISO | RGD:68538 | 6480464 | Valproic Acid affects the expression of RUVBL1 mRNA | CTD | PMID:17292431 | Ruvbl1 | Rat | valproic acid | affects expression | ISO | RGD:68537 | 6480464 | Valproic Acid affects the expression of RUVBL1 mRNA | CTD | PMID:25979313 | Ruvbl1 | Rat | valproic acid | increases expression | ISO | RGD:68537 | 6480464 | Valproic Acid results in increased expression of RUVBL1 mRNA | CTD | PMID:23179753|PMID:29154799 | Ruvbl1 | Rat | zinc dichloride | multiple interactions | ISO | RGD:68537 | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RUVBL1 mRNA] | CTD | PMID:22202117 | |