Gene: Hpse2 (heparanase 2 (inactive)) Rattus norvegicus
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Symbol: Hpse2
Name: heparanase 2 (inactive)
Description: ENCODES a protein that exhibits heparan sulfate proteoglycan binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN glycosaminoglycan degradation pathway; ASSOCIATED WITH urofacial syndrome (ortholog); Urofacial Syndrome 1 (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); aflatoxin B2 (ortholog)
AGR Description: Predicted to have heparan sulfate proteoglycan binding activity; predicted to be involved in extracellular matrix organization and positive regulation of cell population proliferation; predicted to localize to the extracellular matrix; orthologous to human HPSE2 (heparanase 2 (inactive)).
Merged Description: Predicted to have heparan sulfate proteoglycan binding activity; predicted to be involved in extracellular matrix organization and positive regulation of cell population proliferation; predicted to localize to the extracellular matrix; orthologous to human HPSE2 (heparanase 2 (inactive)); PARTICIPATES IN glycosaminoglycan degradation pathway; INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); aflatoxin B2 (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: heparanase 2; heparanase-2; inactive heparanase-2; LOC293955; LOC368128; similar to Heparanase-2 (Hpa2)
Orthologs:
Homo sapiens (human) : HPSE2 (heparanase 2 (inactive))  HGNC  Alliance
Mus musculus (house mouse) : Hpse2 (heparanase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpse2 (heparanase 2 (inactive))
Pan paniscus (bonobo/pygmy chimpanzee) : HPSE2 (heparanase 2 (inactive))
Canis lupus familiaris (dog) : HPSE2 (heparanase 2 (inactive))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpse2 (heparanase 2 (inactive))
Sus scrofa (pig) : HPSE2 (heparanase 2 (inactive))
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01262,020,903 - 263,138,299 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01269,475,568 - 270,128,189 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01270,576,436 - 270,580,047 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41247,458,939 - 248,100,231 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11247,958,907 - 247,971,603 (+)NCBI
Celera1237,417,175 - 238,067,548 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hpse2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307959
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.