Predicted to enable phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and retromer complex binding activity. Predicted to be involved in several processes, including endosomal transport; negative regulation of barbed-end actin filament capping; and protein localization to endosome. Predicted to be located in cytosol; endosome; and nucleolus. Predicted to be part of WASH complex. Predicted to be active in early endosome. Orthologous to human WASHC2A (WASH complex subunit 2A) and WASHC2C (WASH complex subunit 2C); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; allethrin; ammonium chloride.
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of WASHC2C mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of WASHC2C mRNA
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of WASHC2 protein
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of WASHC2C mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of WASHC2C mRNA
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of WASHC2 protein
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of WASHC2 protein
[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of WASHC2C mRNA and [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of WASHC2C gene
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of WASHC2 protein
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of WASHC2C mRNA more ...
[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of WASHC2C mRNA and [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of WASHC2C gene