Mxd1 (max dimerization protein 1) - Rat Genome Database

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Gene: Mxd1 (max dimerization protein 1) Rattus norvegicus
Analyze
Symbol: Mxd1
Name: max dimerization protein 1
RGD ID: 1564525
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including chromatin; mitochondrion; and nucleoplasm. Predicted to be part of Mad-Max complex. Orthologous to human MXD1 (MAX dimerization protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362391; Mad-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84120,654,731 - 120,678,972 (-)NCBIGRCr8
GRCr8 Ensembl4120,654,731 - 120,675,129 (-)EnsemblGRCr8 Ensembl
mRatBN7.24119,097,353 - 119,118,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,097,353 - 119,117,751 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4124,569,846 - 124,590,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04120,344,579 - 120,365,000 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,968,838 - 118,989,263 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04118,451,752 - 118,472,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,449,882 - 118,472,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,021,767 - 183,042,167 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,801,932 - 120,822,346 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4108,067,388 - 108,087,863 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxynon-2-enal  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzoates  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
curcumin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ethylbenzene  (ISO)
eugenol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glucose  (ISO)
ibuprofen  (ISO)
iron dichloride  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
o-xylene  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
Selamectin  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (IEA,ISO)
cytosol  (IEA,ISO)
Mad-Max complex  (IEA,ISO)
mitochondrion  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Histone arginine methylation in cocaine action in the nucleus accumbens. Damez-Werno DM, etal., Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9623-8. doi: 10.1073/pnas.1605045113. Epub 2016 Aug 9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10723141   PMID:12837246  


Genomics

Comparative Map Data
Mxd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84120,654,731 - 120,678,972 (-)NCBIGRCr8
GRCr8 Ensembl4120,654,731 - 120,675,129 (-)EnsemblGRCr8 Ensembl
mRatBN7.24119,097,353 - 119,118,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,097,353 - 119,117,751 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4124,569,846 - 124,590,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04120,344,579 - 120,365,000 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,968,838 - 118,989,263 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04118,451,752 - 118,472,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,449,882 - 118,472,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,021,767 - 183,042,167 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,801,932 - 120,822,346 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4108,067,388 - 108,087,863 (-)NCBICelera
Cytogenetic Map4q34NCBI
MXD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38269,915,109 - 69,942,945 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl269,897,688 - 69,942,945 (+)EnsemblGRCh38hg38GRCh38
GRCh37270,142,241 - 70,170,077 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,995,707 - 70,023,581 (+)NCBINCBI36Build 36hg18NCBI36
Build 34270,053,967 - 70,077,256NCBI
Celera269,993,381 - 70,021,239 (+)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef269,878,174 - 69,906,081 (+)NCBIHuRef
CHM1_1270,071,823 - 70,099,727 (+)NCBICHM1_1
T2T-CHM13v2.0269,926,849 - 69,954,666 (+)NCBIT2T-CHM13v2.0
Mxd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,624,026 - 86,646,099 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,624,024 - 86,646,143 (-)EnsemblGRCm39 Ensembl
GRCm38686,647,044 - 86,669,234 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,647,042 - 86,669,161 (-)EnsemblGRCm38mm10GRCm38
MGSCv37686,597,038 - 86,619,153 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36686,616,160 - 86,634,688 (-)NCBIMGSCv36mm8
Celera688,584,673 - 88,606,787 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.75NCBI
Mxd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542415,209,609 - 15,235,667 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542415,209,609 - 15,235,396 (-)NCBIChiLan1.0ChiLan1.0
MXD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21256,451,227 - 56,505,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A56,474,284 - 56,500,079 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A69,957,798 - 70,002,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A71,074,998 - 71,102,845 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A71,074,998 - 71,102,838 (+)Ensemblpanpan1.1panPan2
MXD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,550,232 - 68,572,950 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1068,549,533 - 68,571,538 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1068,440,021 - 68,462,599 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01069,571,772 - 69,592,697 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1069,571,524 - 69,593,914 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11069,291,187 - 69,312,094 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01069,553,292 - 69,575,921 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01069,851,763 - 69,872,682 (+)NCBIUU_Cfam_GSD_1.0
Mxd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629214,417,985 - 14,443,722 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649114,127,547 - 14,153,322 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649114,127,581 - 14,152,118 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MXD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl372,517,837 - 72,545,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1372,517,829 - 72,545,302 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2375,914,561 - 75,939,811 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MXD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11437,181,424 - 37,209,262 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1437,181,329 - 37,209,222 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604574,789,032 - 74,817,057 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mxd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247623,462,360 - 3,489,406 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247623,461,436 - 3,488,553 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mxd1
43 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:253
Count of miRNA genes:169
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000023856
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat

Markers in Region
RH141918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24119,097,380 - 119,097,589 (+)MAPPERmRatBN7.2
Rnor_6.04118,451,780 - 118,451,988NCBIRnor6.0
Rnor_5.04183,021,795 - 183,022,003UniSTSRnor5.0
RGSC_v3.44120,801,960 - 120,802,168UniSTSRGSC3.4
Celera4108,067,416 - 108,067,624UniSTS
RH 3.4 Map4695.8UniSTS
Cytogenetic Map4q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000023856   ⟹   ENSRNOP00000023856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4120,654,731 - 120,675,129 (-)Ensembl
mRatBN7.2 Ensembl4119,097,353 - 119,117,751 (-)Ensembl
Rnor_6.0 Ensembl4118,449,882 - 118,472,179 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000122422   ⟹   ENSRNOP00000102991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4120,654,731 - 120,674,863 (-)Ensembl
RefSeq Acc Id: NM_001100749   ⟹   NP_001094219
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84120,654,731 - 120,675,129 (-)NCBI
mRatBN7.24119,097,353 - 119,117,751 (-)NCBI
Rnor_6.04118,451,752 - 118,472,150 (-)NCBI
Rnor_5.04183,021,767 - 183,042,167 (-)NCBI
RGSC_v3.44120,801,932 - 120,822,346 (-)RGD
Celera4108,067,388 - 108,087,863 (-)RGD
Sequence:
RefSeq Acc Id: XM_063286285   ⟹   XP_063142355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84120,657,115 - 120,678,972 (-)NCBI
RefSeq Acc Id: NP_001094219   ⟸   NM_001100749
- UniProtKB: F1LRY0 (UniProtKB/TrEMBL),   Q6TV20 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023856   ⟸   ENSRNOT00000023856
RefSeq Acc Id: XP_063142355   ⟸   XM_063286285
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000102991   ⟸   ENSRNOT00000122422
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LRY0-F1-model_v2 AlphaFold F1LRY0 1-232 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693211
Promoter ID:EPDNEW_R3736
Type:initiation region
Name:Mxd1_1
Description:max dimerization protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04118,472,165 - 118,472,225EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564525 AgrOrtholog
BioCyc Gene G2FUF-43886 BioCyc
Ensembl Genes ENSRNOG00000017720 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023856 ENTREZGENE
  ENSRNOT00000023856.6 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro HLH_DNA-bd UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  MXD1 UniProtKB/TrEMBL
KEGG Report rno:362391 UniProtKB/TrEMBL
NCBI Gene 362391 ENTREZGENE
PANTHER MAX DIMERIZATION, MAD UniProtKB/TrEMBL
  PTHR11969:SF18 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PhenoGen Mxd1 PhenoGen
PROSITE HLH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017720 RatGTEx
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP HLH_basic UniProtKB/TrEMBL
UniProt A6IAY6_RAT UniProtKB/TrEMBL
  A6IAY7_RAT UniProtKB/TrEMBL
  A6IAY8_RAT UniProtKB/TrEMBL
  F1LRY0 ENTREZGENE, UniProtKB/TrEMBL
  Q6TV20 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Mxd1  max dimerization protein 1  LOC362391    Symbol updated 1299863 APPROVED
2006-02-09 LOC362391  max dimerization protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL