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Gene: Cln8 (CLN8, transmembrane ER and ERGIC protein) Rattus norvegicus
Symbol: Cln8
Name: CLN8, transmembrane ER and ERGIC protein
RGD ID: 1359518
Description: Predicted to have ceramide binding activity. Predicted to be involved in several processes, including adult walking behavior; glutamate reuptake; and neurofilament cytoskeleton organization. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum-Golgi intermediate compartment. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 8 and neuronal ceroid lipofuscinosis 8 northern epilepsy variant. Orthologous to human CLN8 (CLN8 transmembrane ER and ERGIC protein); INTERACTS WITH bisphenol A; endosulfan; enniatin.
Type: protein-coding
Also known as: ceroid-lipofuscinosis, neuronal 8; ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation); MGC93871
Homo sapiens (human) : CLN8 (CLN8 transmembrane ER and ERGIC protein)  HGNC  Alliance
Mus musculus (house mouse) : Cln8 (CLN8 transmembrane ER and ERGIC protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cln8 (CLN8 transmembrane ER and ERGIC protein)
Pan paniscus (bonobo/pygmy chimpanzee) : CLN8 (CLN8 transmembrane ER and ERGIC protein)
Canis lupus familiaris (dog) : CLN8 (CLN8 transmembrane ER and ERGIC protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cln8 (CLN8 transmembrane ER and ERGIC protein)
Sus scrofa (pig) : CLN8 (CLN8 transmembrane ER and ERGIC protein)
Chlorocebus sabaeus (African green monkey) : CLN8 (CLN8 transmembrane ER and ERGIC protein)
Heterocephalus glaber (naked mole-rat) : Cln8 (CLN8 transmembrane ER and ERGIC protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01679,828,321 - 79,838,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1679,828,324 - 79,838,212 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01679,403,685 - 79,413,576 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41679,569,745 - 79,579,636 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11679,570,012 - 79,579,901 (-)NCBI
Celera1672,565,615 - 72,575,506 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cln8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359518
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.