Gene: Eif6 (eukaryotic translation initiation factor 6) Rattus norvegicus
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Symbol: Eif6
Name: eukaryotic translation initiation factor 6
Description: ENCODES a protein that exhibits ribosome binding (ortholog); INVOLVED IN gene silencing by miRNA (ortholog); mature ribosome assembly (ortholog); miRNA mediated inhibition of translation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cytoplasm (ortholog); intermediate filament (ortholog); lamin filament (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A
AGR Description: Predicted to have ribosomal large subunit binding activity and ribosome binding activity; predicted to be involved in several processes, including regulation of cellular biosynthetic process, regulation of glycolytic process, and ribonucleoprotein complex assembly; predicted to localize to the cytosol, intracellular organelle, and preribosome, large subunit precursor; orthologous to human EIF6 (eukaryotic translation initiation factor 6).
Merged Description: Predicted to have ribosomal large subunit binding activity and ribosome binding activity; predicted to be involved in several processes, including regulation of cellular biosynthetic process, regulation of glycolytic process, and ribonucleoprotein complex assembly; predicted to localize to the cytosol, intracellular organelle, and preribosome, large subunit precursor; orthologous to human EIF6 (eukaryotic translation initiation factor 6); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eIF-6; integrin beta 4 binding protein; Itgb4bp; LOC305506; MGC124669
Orthologs:
Homo sapiens (human) : EIF6 (eukaryotic translation initiation factor 6)  HGNC  Alliance
Mus musculus (house mouse) : Eif6 (eukaryotic translation initiation factor 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eif6 (eukaryotic translation initiation factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : EIF6 (eukaryotic translation initiation factor 6)
Canis lupus familiaris (dog) : EIF6 (eukaryotic translation initiation factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eif6 (eukaryotic translation initiation factor 6)
Sus scrofa (pig) : EIF6 (eukaryotic translation initiation factor 6)
more info ...
Related Pseudogenes: Eif6-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03151,356,867 - 151,363,201 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03157,722,078 - 157,728,394 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11487,483,901 - 87,491,947 (-)NCBI
Celera3143,049,279 - 143,055,527 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Eif6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305373
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.