Mt-nd3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3) - Rat Genome Database

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Gene: Mt-nd3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3) Rattus norvegicus
Analyze
Symbol: Mt-nd3
Name: mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
RGD ID: 620557
Description: Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in cellular response to glucocorticoid stimulus; response to light intensity; and response to oxidative stress. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Used to study Huntington's disease and Parkinson's disease. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and Parkinson's disease. Orthologous to human MT-ND3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: mitochondrially encoded NADH dehydrogenase 3; NADH dehydrogenase 3, mitochondrial; NADH dehydrogenase subunit 3; Nd3
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2MT9,451 - 9,798 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblMT9,451 - 9,798 (+)Ensembl
Rnor_6.0MT9,451 - 9,798 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblMT9,451 - 9,798 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0MT9,451 - 9,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4MT9,451 - 9,798 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic MapMT NCBI


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations. Bose R, etal., Cell Death Dis. 2010 Nov 4;1:e92.
2. The complete nucleotide sequence of the Rattus norvegicus mitochondrial genome: cryptic signals revealed by comparative analysis between vertebrates. Gadaleta G, etal., J Mol Evol 1989 Jun;28(6):497-516.
3. Mitochondrial DNA fragments released through the permeability transition pore correspond to specific gene size. Garcia N and Chavez E, Life Sci. 2007 Sep 15;81(14):1160-6. Epub 2007 Aug 28.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice. Gupta A, etal., Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1;35(4):974-81. Epub 2011 Feb 1.
6. Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina. Huang H, etal., Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2489-96.
7. Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population. Huerta C, etal., J Neurol Sci. 2005 Sep 15;236(1-2):49-54.
8. Identification of the mitochondrial NADH dehydrogenase subunit 3 (ND3) as a thyroid hormone regulated gene by whole genome PCR analysis. Iglesias T, etal., Biochem Biophys Res Commun. 1995 May 25;210(3):995-1000.
9. Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson's disease. Kaur H, etal., Neurochem Res. 2011 Aug;36(8):1435-43. Epub 2011 Apr 12.
10. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
11. Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease. Kumar P, etal., Behav Pharmacol. 2010 May;21(3):217-30.
12. De novo mutations in the mitochondrial ND3 gene as a cause of infantile mitochondrial encephalopathy and complex I deficiency. McFarland R, etal., Ann Neurol. 2004 Jan;55(1):58-64.
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Acetyl-L-carnitine ameliorates mitochondrial dysfunction following contusion spinal cord injury. Patel SP, etal., J Neurochem. 2010 Jul;114(1):291-301. Epub 2010 Apr 23.
15. GOA pipeline RGD automated data pipeline
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Comprehensive gene review and curation RGD comprehensive gene curation
19. Mitochondrial ND3 as the novel causative gene for Leber hereditary optic neuropathy and dystonia. Wang K, etal., Neurogenetics. 2009 Oct;10(4):337-45. Epub 2009 May 21.

Genomics

Comparative Map Data
Mt-nd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2MT9,451 - 9,798 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblMT9,451 - 9,798 (+)Ensembl
Rnor_6.0MT9,451 - 9,798 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblMT9,451 - 9,798 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0MT9,451 - 9,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4MT9,451 - 9,798 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic MapMT NCBI
MT-ND3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38MT10,059 - 10,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblMT10,059 - 10,404 (+)EnsemblGRCh38hg38GRCh38
GRCh37MT10,059 - 10,404 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36MT10,060 - 10,405 (+)NCBINCBI36hg18NCBI36
mt-Nd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39MT9,459 - 9,806 (+)NCBIGRCm39mm39
GRCm39 EnsemblMT9,459 - 9,806 (+)Ensembl
GRCm38MT9,459 - 9,806 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblMT9,459 - 9,806 (+)EnsemblGRCm38mm10GRCm38
MGSCv37MT9,459 - 9,806 (+)NCBIGRCm37mm9NCBIm37
MT-ND3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1MT9,496 - 9,841 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblMT9,496 - 9,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaMT9,496 - 9,841 (+)NCBI
MT-ND3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblMT10,653 - 10,998 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1MT10,653 - 10,998 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2MT10,653 - 10,998 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:11
Count of miRNA genes:9
Interacting mature miRNAs:10
Transcripts:ENSRNOT00000041241
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 3 43 51 35 9 35 8 11 74 35 38 10 8
Medium 6 6 10 6 3 1
Low
Below cutoff

Sequence

Nucleotide Sequences
GenBank Nucleotide AF504920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ428514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY172581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY769440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ673917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU104719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU104726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ919771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU997608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU997610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU997611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM152027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM152028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX105355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX105356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF011917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KJ530565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KJ939360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KJ939361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM009112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM009113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM009114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM114603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM114604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM114605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM114606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM114607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM114608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM577635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM657952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM657953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM820831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM820832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM820833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM820834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM820835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM820837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP100657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP233827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP233832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP241960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP244683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000041241   ⟹   ENSRNOP00000039725
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblMT9,451 - 9,798 (+)Ensembl
Rnor_6.0 EnsemblMT9,451 - 9,798 (+)Ensembl
Protein Sequences
Protein RefSeqs YP_665636 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAM28880 (Get FASTA)   NCBI Sequence Viewer  
  AAN77601 (Get FASTA)   NCBI Sequence Viewer  
  AAV31046 (Get FASTA)   NCBI Sequence Viewer  
  ABG11768 (Get FASTA)   NCBI Sequence Viewer  
  ABG11780 (Get FASTA)   NCBI Sequence Viewer  
  ABG11794 (Get FASTA)   NCBI Sequence Viewer  
  ABG11808 (Get FASTA)   NCBI Sequence Viewer  
  ABG11833 (Get FASTA)   NCBI Sequence Viewer  
  ABG11846 (Get FASTA)   NCBI Sequence Viewer  
  ABG11859 (Get FASTA)   NCBI Sequence Viewer  
  ABG11872 (Get FASTA)   NCBI Sequence Viewer  
  ABG11885 (Get FASTA)   NCBI Sequence Viewer  
  ABG11898 (Get FASTA)   NCBI Sequence Viewer  
  ABV22515 (Get FASTA)   NCBI Sequence Viewer  
  ABV22522 (Get FASTA)   NCBI Sequence Viewer  
  ACP50287 (Get FASTA)   NCBI Sequence Viewer  
  ACP50300 (Get FASTA)   NCBI Sequence Viewer  
  ACP50313 (Get FASTA)   NCBI Sequence Viewer  
  ACP50326 (Get FASTA)   NCBI Sequence Viewer  
  ACP50339 (Get FASTA)   NCBI Sequence Viewer  
  ACP50352 (Get FASTA)   NCBI Sequence Viewer  
  ACP50365 (Get FASTA)   NCBI Sequence Viewer  
  ACP50378 (Get FASTA)   NCBI Sequence Viewer  
  ACP50391 (Get FASTA)   NCBI Sequence Viewer  
  ACP50404 (Get FASTA)   NCBI Sequence Viewer  
  ACP50417 (Get FASTA)   NCBI Sequence Viewer  
  ACP50430 (Get FASTA)   NCBI Sequence Viewer  
  ACP50443 (Get FASTA)   NCBI Sequence Viewer  
  ADE05959 (Get FASTA)   NCBI Sequence Viewer  
  ADE05972 (Get FASTA)   NCBI Sequence Viewer  
  ADE05985 (Get FASTA)   NCBI Sequence Viewer  
  ADG85628 (Get FASTA)   NCBI Sequence Viewer  
  ADG85641 (Get FASTA)   NCBI Sequence Viewer  
  AFN06285 (Get FASTA)   NCBI Sequence Viewer  
  AFN06298 (Get FASTA)   NCBI Sequence Viewer  
  AGS12828 (Get FASTA)   NCBI Sequence Viewer  
  AHZ60973 (Get FASTA)   NCBI Sequence Viewer  
  AIU45582 (Get FASTA)   NCBI Sequence Viewer  
  AIU45595 (Get FASTA)   NCBI Sequence Viewer  
  AIU45608 (Get FASTA)   NCBI Sequence Viewer  
  AIU45621 (Get FASTA)   NCBI Sequence Viewer  
  AIU45634 (Get FASTA)   NCBI Sequence Viewer  
  AIU45647 (Get FASTA)   NCBI Sequence Viewer  
  AIU45660 (Get FASTA)   NCBI Sequence Viewer  
  AIU45673 (Get FASTA)   NCBI Sequence Viewer  
  AIU45686 (Get FASTA)   NCBI Sequence Viewer  
  AIU45699 (Get FASTA)   NCBI Sequence Viewer  
  AIU45712 (Get FASTA)   NCBI Sequence Viewer  
  AIY51549 (Get FASTA)   NCBI Sequence Viewer  
  AIZ58329 (Get FASTA)   NCBI Sequence Viewer  
  AIZ58342 (Get FASTA)   NCBI Sequence Viewer  
  AJE26537 (Get FASTA)   NCBI Sequence Viewer  
  AJE61346 (Get FASTA)   NCBI Sequence Viewer  
  AJE61359 (Get FASTA)   NCBI Sequence Viewer  
  AJE61372 (Get FASTA)   NCBI Sequence Viewer  
  AJE61385 (Get FASTA)   NCBI Sequence Viewer  
  AJE61398 (Get FASTA)   NCBI Sequence Viewer  
  AJE61411 (Get FASTA)   NCBI Sequence Viewer  
  AJJ48384 (Get FASTA)   NCBI Sequence Viewer  
  AJJ48756 (Get FASTA)   NCBI Sequence Viewer  
  AJK29988 (Get FASTA)   NCBI Sequence Viewer  
  AJK30564 (Get FASTA)   NCBI Sequence Viewer  
  CAD21566 (Get FASTA)   NCBI Sequence Viewer  
  P05506 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSRNOP00000039725   ⟸   ENSRNOT00000041241

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05506-F1-model_v2 AlphaFold P05506 1-115 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620557 AgrOrtholog
BioCyc Gene G2FUF-13 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
Ensembl Genes ENSRNOG00000033615 Ensembl, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000039725 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000041241 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.1610 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NADH_UbQ/plastoQ_OxRdtase_su3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDAH_ubi_oxred_su3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:26199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 26199 ENTREZGENE
PANTHER PTHR11058 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Oxidored_q4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mt-nd3 PhenoGen
UniProt NU3M_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8SEZ1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary H9KVF5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-03-17 Mt-nd3  mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3  Mt-nd3  mitochondrially encoded NADH dehydrogenase 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Mt-nd3  mitochondrially encoded NADH dehydrogenase 3  mt-Nd3  NADH dehydrogenase 3, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 mt-Nd3  NADH dehydrogenase 3, mitochondrial      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 mt-Nd3  NADH dehydrogenase 3, mitochondrial      Symbol and Name status set to provisional 70820 PROVISIONAL