Sp100 (SP100 nuclear antigen) - Rat Genome Database

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Gene: Sp100 (SP100 nuclear antigen) Rattus norvegicus
Analyze
Symbol: Sp100
Name: SP100 nuclear antigen
RGD ID: 1359550
Description: Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; chromo shadow domain binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including innate immune response; regulation of signal transduction; and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nuclear lumen. Orthologous to human SP100 (SP100 nuclear antigen); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103690030; LOC363269; nuclear antigen Sp100; nuclear autoantigen Sp-100; nuclear autoantigen Sp-100-like; similar to Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2986,310,990 - 86,377,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx994,728,134 - 94,794,889 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0999,856,630 - 99,923,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,237,941 - 98,304,055 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0992,675,103 - 92,718,489 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl992,681,078 - 92,717,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0992,405,689 - 92,449,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0990,732,749 - 90,750,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4984,374,288 - 84,409,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1984,557,706 - 84,593,391 (+)NCBI
Celera983,734,331 - 83,769,903 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxynon-2-enal  (ISO)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dioxygen  (EXP)
diquat  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
geraniol  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
ruxolitinib  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:2258622   PMID:8810287   PMID:9230084   PMID:9412458   PMID:9636146   PMID:9636147   PMID:9973607   PMID:11313457   PMID:11909962   PMID:12470659   PMID:14647468   PMID:15247905  
PMID:15592518   PMID:15767676   PMID:15882967   PMID:16177824   PMID:16873258   PMID:17245429   PMID:17332504   PMID:19135898   PMID:27107012  


Genomics

Comparative Map Data
Sp100
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2986,310,990 - 86,377,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx994,728,134 - 94,794,889 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0999,856,630 - 99,923,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,237,941 - 98,304,055 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0992,675,103 - 92,718,489 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl992,681,078 - 92,717,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0992,405,689 - 92,449,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0990,732,749 - 90,750,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4984,374,288 - 84,409,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1984,557,706 - 84,593,391 (+)NCBI
Celera983,734,331 - 83,769,903 (+)NCBICelera
Cytogenetic Map9q35NCBI
SP100
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,416,201 - 230,545,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,415,942 - 230,545,606 (+)EnsemblGRCh38hg38GRCh38
GRCh372231,280,916 - 231,410,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,989,115 - 231,118,561 (+)NCBINCBI36Build 36hg18NCBI36
Build 342231,106,485 - 231,206,745NCBI
Celera2225,057,025 - 225,186,692 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2223,121,005 - 223,250,289 (+)NCBIHuRef
CHM1_12231,286,764 - 231,416,096 (+)NCBICHM1_1
T2T-CHM13v2.02230,899,281 - 231,028,667 (+)NCBIT2T-CHM13v2.0
Sp100
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39185,577,683 - 85,637,719 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl185,577,709 - 85,637,719 (+)EnsemblGRCm39 Ensembl
GRCm38185,649,948 - 85,709,998 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl185,649,988 - 85,709,998 (+)EnsemblGRCm38mm10GRCm38
MGSCv37187,546,625 - 87,606,023 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36187,481,185 - 87,532,732 (+)NCBIMGSCv36mm8
Celera188,624,849 - 88,674,129 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.6NCBI
Sp100
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554534,773,030 - 4,853,814 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554534,774,739 - 4,856,238 (-)NCBIChiLan1.0ChiLan1.0
SP100
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12B133,062,928 - 133,192,182 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B117,673,152 - 117,799,911 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B236,474,298 - 236,601,277 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B236,496,446 - 236,601,096 (+)Ensemblpanpan1.1panPan2
SP100
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12542,538,428 - 42,635,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2542,538,571 - 42,635,649 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2543,163,525 - 43,261,071 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02542,794,971 - 42,892,656 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2542,795,086 - 42,892,647 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12542,724,896 - 42,822,209 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02542,566,980 - 42,664,684 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02542,722,157 - 42,819,867 (+)NCBIUU_Cfam_GSD_1.0
Sp100
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303184,708,642 - 184,803,432 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365256,136,343 - 6,231,051 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100517129
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115131,299,923 - 131,381,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215145,104,815 - 145,137,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SP100
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110116,454,261 - 116,587,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10116,459,050 - 116,590,215 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604082,883,256 - 83,027,176 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp100
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248433,983,040 - 4,061,930 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248433,982,920 - 4,058,081 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sp100
299 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:63
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000034152
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)98636963192058970Rat

Markers in Region
RH144235  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2986,329,251 - 86,329,352 (+)MAPPERmRatBN7.2
Rnor_6.0992,699,869 - 92,699,969NCBIRnor6.0
Rnor_5.0992,430,455 - 92,430,555UniSTSRnor5.0
RGSC_v3.4984,392,408 - 84,392,508UniSTSRGSC3.4
Celera983,752,335 - 83,752,435UniSTS
Cytogenetic Map9q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 8 10 2 19 2 14 11
Low 31 47 39 39 8 11 58 33 23 8
Below cutoff 4 14 2 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001014220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005488939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000034152   ⟹   ENSRNOP00000033655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,045 - 86,346,819 (+)Ensembl
Rnor_6.0 Ensembl992,681,078 - 92,717,929 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080956   ⟹   ENSRNOP00000073910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,376,375 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095650   ⟹   ENSRNOP00000080041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,376,667 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102336   ⟹   ENSRNOP00000097798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108829   ⟹   ENSRNOP00000079433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,376,381 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110612   ⟹   ENSRNOP00000093445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111279   ⟹   ENSRNOP00000081917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,376,667 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111514   ⟹   ENSRNOP00000084228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112510   ⟹   ENSRNOP00000079517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,377,034 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116342   ⟹   ENSRNOP00000082712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,311,032 - 86,376,667 (+)Ensembl
RefSeq Acc Id: NM_001014220   ⟹   NP_001014242
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,311,118 - 86,346,819 (+)NCBI
Rnor_6.0992,675,103 - 92,718,489 (+)NCBI
Rnor_5.0992,405,689 - 92,449,075 (+)NCBI
RGSC_v3.4984,374,288 - 84,409,976 (+)RGD
Celera983,734,331 - 83,769,903 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401802   ⟹   NP_001388731
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,311,032 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_006245338   ⟹   XP_006245400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,349,779 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083898   ⟹   XP_038939826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083899   ⟹   XP_038939827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083900   ⟹   XP_038939828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083902   ⟹   XP_038939830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083903   ⟹   XP_038939831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083905   ⟹   XP_038939833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083906   ⟹   XP_038939834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083907   ⟹   XP_038939835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083908   ⟹   XP_038939836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083909   ⟹   XP_038939837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083910   ⟹   XP_038939838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083911   ⟹   XP_038939839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083912   ⟹   XP_038939840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083913   ⟹   XP_038939841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083914   ⟹   XP_038939842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,377,036 (+)NCBI
RefSeq Acc Id: XM_039083915   ⟹   XP_038939843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,349,779 (+)NCBI
RefSeq Acc Id: XR_005488939
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2986,310,990 - 86,375,511 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001014242   ⟸   NM_001014220
- Peptide Label: isoform 2
- UniProtKB: Q5XI80 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000033655   ⟸   ENSRNOT00000034152
RefSeq Acc Id: XP_038939826   ⟸   XM_039083898
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939831   ⟸   XM_039083903
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939835   ⟸   XM_039083907
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZPT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939839   ⟸   XM_039083911
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZPT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939841   ⟸   XM_039083913
- Peptide Label: isoform X15
- UniProtKB: A0A8I5ZPT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939842   ⟸   XM_039083914
- Peptide Label: isoform X16
- UniProtKB: A0A8I5ZMP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939828   ⟸   XM_039083900
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939833   ⟸   XM_039083905
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939830   ⟸   XM_039083902
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939836   ⟸   XM_039083908
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939834   ⟸   XM_039083906
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939838   ⟸   XM_039083910
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939827   ⟸   XM_039083899
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GKN6 (UniProtKB/TrEMBL),   A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939837   ⟸   XM_039083909
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939840   ⟸   XM_039083912
- Peptide Label: isoform X14
- UniProtKB: A0A8I6ATB4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939843   ⟸   XM_039083915
- Peptide Label: isoform X17
RefSeq Acc Id: XP_006245400   ⟸   XM_006245338
- Peptide Label: isoform X18
- UniProtKB: F7FPF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000079433   ⟸   ENSRNOT00000108829
RefSeq Acc Id: ENSRNOP00000084228   ⟸   ENSRNOT00000111514
RefSeq Acc Id: ENSRNOP00000097798   ⟸   ENSRNOT00000102336
RefSeq Acc Id: ENSRNOP00000079517   ⟸   ENSRNOT00000112510
RefSeq Acc Id: ENSRNOP00000081917   ⟸   ENSRNOT00000111279
RefSeq Acc Id: ENSRNOP00000073910   ⟸   ENSRNOT00000080956
RefSeq Acc Id: ENSRNOP00000082712   ⟸   ENSRNOT00000116342
RefSeq Acc Id: ENSRNOP00000080041   ⟸   ENSRNOT00000095650
RefSeq Acc Id: ENSRNOP00000093445   ⟸   ENSRNOT00000110612
RefSeq Acc Id: NP_001388731   ⟸   NM_001401802
- Peptide Label: isoform 1
- UniProtKB: A0A8I5ZXL2 (UniProtKB/TrEMBL)
Protein Domains
HSR   PHD-type   SAND

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K6R2-F1-model_v2 AlphaFold A0A0G2K6R2 1-132 view protein structure
AF-F7FPF5-F1-model_v2 AlphaFold F7FPF5 1-338 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359550 AgrOrtholog
BioCyc Gene G2FUF-26940 BioCyc
Ensembl Genes ENSRNOG00000022769 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000033655 ENTREZGENE
  ENSRNOP00000033655.7 UniProtKB/TrEMBL
  ENSRNOP00000073910 ENTREZGENE
  ENSRNOP00000073910.2 UniProtKB/TrEMBL
  ENSRNOP00000079433.1 UniProtKB/TrEMBL
  ENSRNOP00000079517.1 UniProtKB/TrEMBL
  ENSRNOP00000080041 ENTREZGENE
  ENSRNOP00000080041.1 UniProtKB/TrEMBL
  ENSRNOP00000081917 ENTREZGENE
  ENSRNOP00000081917.1 UniProtKB/TrEMBL
  ENSRNOP00000082712.1 UniProtKB/TrEMBL
  ENSRNOP00000084228 ENTREZGENE
  ENSRNOP00000084228.1 UniProtKB/TrEMBL
  ENSRNOP00000093445 ENTREZGENE
  ENSRNOP00000093445.1 UniProtKB/TrEMBL
  ENSRNOP00000097798 ENTREZGENE
  ENSRNOP00000097798.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034152 ENTREZGENE
  ENSRNOT00000034152.7 UniProtKB/TrEMBL
  ENSRNOT00000080956 ENTREZGENE
  ENSRNOT00000080956.2 UniProtKB/TrEMBL
  ENSRNOT00000095650 ENTREZGENE
  ENSRNOT00000095650.1 UniProtKB/TrEMBL
  ENSRNOT00000102336 ENTREZGENE
  ENSRNOT00000102336.1 UniProtKB/TrEMBL
  ENSRNOT00000108829.1 UniProtKB/TrEMBL
  ENSRNOT00000110612 ENTREZGENE
  ENSRNOT00000110612.1 UniProtKB/TrEMBL
  ENSRNOT00000111279 ENTREZGENE
  ENSRNOT00000111279.1 UniProtKB/TrEMBL
  ENSRNOT00000111514 ENTREZGENE
  ENSRNOT00000111514.1 UniProtKB/TrEMBL
  ENSRNOT00000112510.1 UniProtKB/TrEMBL
  ENSRNOT00000116342.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.10.390.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109918 IMAGE-MGC_LOAD
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  SAND-like_dom_sf UniProtKB/TrEMBL
  SAND_dom UniProtKB/TrEMBL
  Sp100 UniProtKB/TrEMBL
  Sp110/Sp140/Sp140L UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:363269 UniProtKB/TrEMBL
MGC_CLONE MGC:94860 IMAGE-MGC_LOAD
NCBI Gene 363269 ENTREZGENE
PANTHER NUCLEAR AUTOANTIGEN SP-100 UniProtKB/TrEMBL
  PTHR46386 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
  Sp100 UniProtKB/TrEMBL
PhenoGen Sp100 PhenoGen
PROSITE HSR UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
Superfamily-SCOP SSF47370 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
  SSF63763 UniProtKB/TrEMBL
UniProt A0A0G2K6R2_RAT UniProtKB/TrEMBL
  A0A8I5ZMP9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVG0_RAT UniProtKB/TrEMBL
  A0A8I5ZXL2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5F7_RAT UniProtKB/TrEMBL
  A0A8I6G6P9_RAT UniProtKB/TrEMBL
  A0A8I6GKN6 ENTREZGENE, UniProtKB/TrEMBL
  F7FPF5 ENTREZGENE, UniProtKB/TrEMBL
  Q5XI80 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Sp100  SP100 nuclear antigen  LOC103690030  nuclear autoantigen Sp-100-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103690030  nuclear autoantigen Sp-100-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-18 Sp100  SP100 nuclear antigen  Sp100  nuclear antigen Sp100  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Sp100  nuclear antigen Sp100  LOC363269  similar to Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 LOC363269  similar to Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein)      Symbol and Name status set to provisional 70820 PROVISIONAL