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Gene: Myh11 (myosin heavy chain 11) Rattus norvegicus
Symbol: Myh11
Name: myosin heavy chain 11
RGD ID: 3136
Description: Predicted to have motor activity. Predicted to be involved in cardiac muscle fiber development; elastic fiber assembly; and smooth muscle contraction. Predicted to localize to brush border; contractile fiber; and stress fiber. Human ortholog(s) of this gene implicated in patent ductus arteriosus and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: LOC497849; myosin heavy chain 21; myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; myosin-11; RGD1564935; similar to Myh11 protein; SMMHC; smooth muscle myosin heavy chain
Homo sapiens (human) : MYH11 (myosin heavy chain 11)  HGNC  Alliance
Mus musculus (house mouse) : Myh11 (myosin, heavy polypeptide 11, smooth muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh11 (myosin heavy chain 11)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH11 (myosin heavy chain 11)
Canis lupus familiaris (dog) : MYH11 (myosin heavy chain 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh11 (myosin heavy chain 11)
Sus scrofa (pig) : MYH11 (myosin heavy chain 11)
Chlorocebus sabaeus (African green monkey) : MYH11 (myosin heavy chain 11)
Heterocephalus glaber (naked mole-rat) : Myh11 (myosin heavy chain 11)
more info ...
Is Marker For: QTLs:   Bp133  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010764,421 - 859,184 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10764,421 - 859,184 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01011,444,263 - 11,538,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410666,709 - 776,540 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110767,179 - 776,535 (+)NCBI
Celera1011,333,535 - 11,428,078 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Myh11
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3136
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.