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Gene: Myh11 (myosin heavy chain 11) Rattus norvegicus
Symbol: Myh11
Name: myosin heavy chain 11
Description: Predicted to have motor activity. Predicted to be involved in cardiac muscle fiber development; elastic fiber assembly; and smooth muscle contraction. Predicted to localize to the brush border; cytoskeleton; and smooth muscle contractile fiber. Human ortholog(s) of this gene implicated in patent ductus arteriosus and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11); PARTICIPATES IN myocarditis pathway; INTERACTS WITH (RS)-amphetamine; 1,2,4-trimethylbenzene; 17beta-estradiol.
Type: protein-coding
Also known as: LOC497849; myosin heavy chain 21; myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; myosin-11; RGD1564935; similar to Myh11 protein; SMMHC; smooth muscle myosin heavy chain
Homo sapiens (human) : MYH11 (myosin heavy chain 11)  HGNC  Alliance
Mus musculus (house mouse) : Myh11 (myosin, heavy polypeptide 11, smooth muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh11 (myosin heavy chain 11)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH11 (myosin heavy chain 11)
Canis lupus familiaris (dog) : MYH11 (myosin heavy chain 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh11 (myosin heavy chain 11)
Sus scrofa (pig) : MYH11 (myosin heavy chain 11)
more info ...
Is Marker For: QTLs:   Bp133  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010764,421 - 859,184 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01011,444,263 - 11,538,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410666,709 - 776,540 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110767,179 - 776,535 (+)NCBI
Celera1011,333,535 - 11,428,078 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Myh11
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3136
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.