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Gene: Myh11 (myosin, heavy polypeptide 11, smooth muscle) Mus musculus
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Symbol: Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Description: Exhibits motor activity. Involved in smooth muscle contraction. Localizes to brush border; contractile fiber; and stress fiber. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and liver and biliary system. Human ortholog(s) of this gene implicated in patent ductus arteriosus and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV071570; myosin heavy chain 11, smooth muscle; myosin heavy chain, smooth muscle isoform; myosin-11; SM1; SM2; smMHC
Orthologs:
Homo sapiens (human) : MYH11 (myosin heavy chain 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myh11 (myosin heavy chain 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh11 (myosin heavy chain 11)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH11 (myosin heavy chain 11)
Canis lupus familiaris (dog) : MYH11 (myosin heavy chain 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh11 (myosin heavy chain 11)
Sus scrofa (pig) : MYH11 (myosin heavy chain 11)
Chlorocebus sabaeus (African green monkey) : MYH11 (myosin heavy chain 11)
Heterocephalus glaber (naked mole-rat) : Myh11 (myosin heavy chain 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1614,194,535 - 14,291,372 (-)EnsemblGRCm38mm10GRCm38
GRCm381614,194,527 - 14,292,188 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371614,194,620 - 14,291,501 (-)NCBIGRCm37mm9NCBIm37
MGSCv361614,108,478 - 14,204,941 (-)NCBImm8
Celera1614,801,022 - 14,896,521 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myh11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10947
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.