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Gene: Myh11 (myosin, heavy polypeptide 11, smooth muscle) Mus musculus
Symbol: Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Description: Exhibits motor activity. Involved in smooth muscle contraction. Localizes to brush border; contractile fiber; and stress fiber. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and liver and biliary system. Human ortholog(s) of this gene implicated in patent ductus arteriosus and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV071570; myosin heavy chain 11, smooth muscle; myosin heavy chain, smooth muscle isoform; myosin-11; SM1; SM2; smMHC
Homo sapiens (human) : MYH11 (myosin heavy chain 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myh11 (myosin heavy chain 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh11 (myosin heavy chain 11)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH11 (myosin heavy chain 11)
Canis lupus familiaris (dog) : MYH11 (myosin heavy chain 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh11 (myosin heavy chain 11)
Sus scrofa (pig) : MYH11 (myosin heavy chain 11)
Chlorocebus sabaeus (African green monkey) : MYH11 (myosin heavy chain 11)
Heterocephalus glaber (naked mole-rat) : Myh11 (myosin heavy chain 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1614,194,535 - 14,291,372 (-)EnsemblGRCm38mm10GRCm38
GRCm381614,194,527 - 14,292,188 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371614,194,620 - 14,291,501 (-)NCBIGRCm37mm9NCBIm37
MGSCv361614,108,478 - 14,204,941 (-)NCBImm8
Celera1614,801,022 - 14,896,521 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Myh11
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10947
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.