Bpnt1 (3'(2'), 5'-bisphosphate nucleotidase 1) - Rat Genome Database

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Gene: Bpnt1 (3'(2'), 5'-bisphosphate nucleotidase 1) Rattus norvegicus
Analyze
Symbol: Bpnt1
Name: 3'(2'), 5'-bisphosphate nucleotidase 1
RGD ID: 621833
Description: Enables 3'(2'),5'-bisphosphate nucleotidase activity; inositol-1,4-bisphosphate 1-phosphatase activity; and magnesium ion binding activity. Predicted to be involved in inositol phosphate dephosphorylation and phosphatidylinositol phosphate biosynthetic process. Orthologous to human BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1); PARTICIPATES IN sulfite oxidase deficiency pathway; sulfur metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5'-bisphosphate nucleotidase 1; 3'(2')5'-bisphosphate nucleotidase; 3(2),5-bisphosphate nucleotidase; 3(2)5-bisphosphate nucleotidase; bisphosphate 3'-nucleotidase 1; MGC93112; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; Sal3; scHAL2 analogous 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21396,865,634 - 96,893,506 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,868,580 - 96,893,503 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,367,724 - 99,392,688 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.013100,773,702 - 100,798,609 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01397,949,983 - 97,974,947 (+)NCBIRnor_WKY
Rnor_6.013103,268,045 - 103,292,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,268,068 - 103,292,854 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,941,070 - 107,965,562 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413101,340,544 - 101,367,549 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113101,540,167 - 101,556,592 (+)NCBI
Celera1396,381,982 - 96,406,864 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3'-phosphoadenosine 5'-phosphate phosphatase and inositol-polyphosphate 1-phosphatase. Lopez-Coronado JM, etal., J Biol Chem 1999 Jun 4;274(23):16034-9.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy. Patel S, etal., J Mol Biol 2002 Jan 25;315(4):677-85.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10224133   PMID:12477932   PMID:15489334   PMID:23376485  


Genomics

Comparative Map Data
Bpnt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21396,865,634 - 96,893,506 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,868,580 - 96,893,503 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,367,724 - 99,392,688 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.013100,773,702 - 100,798,609 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01397,949,983 - 97,974,947 (+)NCBIRnor_WKY
Rnor_6.013103,268,045 - 103,292,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,268,068 - 103,292,854 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,941,070 - 107,965,562 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413101,340,544 - 101,367,549 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113101,540,167 - 101,556,592 (+)NCBI
Celera1396,381,982 - 96,406,864 (+)NCBICelera
Cytogenetic Map13q26NCBI
BPNT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381220,057,482 - 220,089,788 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1220,057,482 - 220,090,462 (-)EnsemblGRCh38hg38GRCh38
GRCh371220,230,824 - 220,263,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,297,447 - 218,329,814 (-)NCBINCBI36Build 36hg18NCBI36
Build 341216,619,220 - 216,651,579NCBI
Celera1193,450,034 - 193,482,399 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1190,905,457 - 190,937,542 (-)NCBIHuRef
CHM1_11221,503,635 - 221,536,002 (-)NCBICHM1_1
T2T-CHM13v2.01219,296,762 - 219,329,061 (-)NCBIT2T-CHM13v2.0
Bpnt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,061,619 - 185,089,974 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,064,346 - 185,089,974 (+)EnsemblGRCm39 Ensembl
GRCm381185,329,428 - 185,357,777 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,332,149 - 185,357,777 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,156,038 - 187,181,648 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,032,947 - 187,058,557 (+)NCBIMGSCv36mm8
Celera1192,281,814 - 192,307,391 (+)NCBICelera
Cytogenetic Map1H5NCBI
Bpnt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555203,524,684 - 3,544,666 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555203,521,096 - 3,543,255 (+)NCBIChiLan1.0ChiLan1.0
BPNT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11200,667,016 - 200,699,790 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1200,667,016 - 200,699,790 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01195,629,262 - 195,663,144 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
BPNT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,834,642 - 14,857,242 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,834,643 - 14,857,227 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,877,148 - 14,899,802 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03814,869,796 - 14,892,460 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3814,867,722 - 14,892,448 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13814,880,647 - 14,903,284 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03815,225,675 - 15,248,728 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03815,515,028 - 15,537,177 (-)NCBIUU_Cfam_GSD_1.0
Bpnt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934456,865,682 - 56,890,277 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366502,113,933 - 2,138,487 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BPNT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl109,659,487 - 9,683,912 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1109,659,876 - 9,684,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,741,839 - 11,765,917 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BPNT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1259,489,479 - 9,518,936 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl259,490,763 - 9,519,721 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660559,794,651 - 9,825,120 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bpnt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248353,704,664 - 3,718,129 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248353,704,455 - 3,722,825 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH129031  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21396,893,250 - 96,893,400 (+)MAPPERmRatBN7.2
Rnor_6.013103,292,593 - 103,292,742NCBIRnor6.0
Rnor_5.013107,965,307 - 107,965,456UniSTSRnor5.0
RGSC_v3.413101,367,294 - 101,367,443UniSTSRGSC3.4
Celera1396,406,609 - 96,406,758UniSTS
RH 3.4 Map13656.1UniSTS
Cytogenetic Map13q26UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:137
Count of miRNA genes:109
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000003249
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003249   ⟹   ENSRNOP00000003249
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,868,580 - 96,893,501 (+)Ensembl
Rnor_6.0 Ensembl13103,268,088 - 103,292,845 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088921   ⟹   ENSRNOP00000071594
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,868,580 - 96,893,501 (+)Ensembl
Rnor_6.0 Ensembl13103,268,068 - 103,292,854 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096481   ⟹   ENSRNOP00000080410
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,877,092 - 96,893,503 (+)Ensembl
RefSeq Acc Id: NM_171990   ⟹   NP_741987
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,868,603 - 96,893,506 (+)NCBI
Rnor_6.013103,268,088 - 103,292,848 (+)NCBI
Rnor_5.013107,941,070 - 107,965,562 (+)NCBI
RGSC_v3.413101,340,544 - 101,367,549 (+)RGD
Celera1396,381,982 - 96,406,864 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250429   ⟹   XP_006250491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,868,518 - 96,893,506 (+)NCBI
Rnor_6.013103,268,046 - 103,292,848 (+)NCBI
Rnor_5.013107,941,070 - 107,965,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250430   ⟹   XP_006250492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,868,572 - 96,893,506 (+)NCBI
Rnor_6.013103,268,045 - 103,292,848 (+)NCBI
Rnor_5.013107,941,070 - 107,965,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250431   ⟹   XP_006250493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,868,572 - 96,893,506 (+)NCBI
Rnor_6.013103,268,046 - 103,292,848 (+)NCBI
Rnor_5.013107,941,070 - 107,965,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091064   ⟹   XP_038946992
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,865,634 - 96,893,506 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_741987   ⟸   NM_171990
- UniProtKB: Q9Z1N4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250491   ⟸   XM_006250429
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0V3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250492   ⟸   XM_006250430
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0V3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250493   ⟸   XM_006250431
- Peptide Label: isoform X2
- UniProtKB: Q9Z1N4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071594   ⟸   ENSRNOT00000088921
RefSeq Acc Id: ENSRNOP00000003249   ⟸   ENSRNOT00000003249
RefSeq Acc Id: XP_038946992   ⟸   XM_039091064
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0V3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080410   ⟸   ENSRNOT00000096481

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1N4-F1-model_v2 AlphaFold Q9Z1N4 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699095
Promoter ID:EPDNEW_R9616
Type:initiation region
Name:Bpnt1_1
Description:3'(2'), 5'-bisphosphate nucleotidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013103,268,071 - 103,268,131EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621833 AgrOrtholog
BioCyc Gene G2FUF-16980 BioCyc
Ensembl Genes ENSRNOG00000002378 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003249.6 UniProtKB/TrEMBL
  ENSRNOP00000071594 ENTREZGENE
  ENSRNOP00000071594.1 UniProtKB/TrEMBL
  ENSRNOP00000080410.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003249.7 UniProtKB/TrEMBL
  ENSRNOT00000088921 ENTREZGENE
  ENSRNOT00000088921.2 UniProtKB/TrEMBL
  ENSRNOT00000096481.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7190529 IMAGE-MGC_LOAD
InterPro Inositol_monoP_metal-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Inositol_monophosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Inositol_monophosphatase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64473 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93112 IMAGE-MGC_LOAD
NCBI Gene 64473 ENTREZGENE
Pfam Inositol_P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bpnt1 PhenoGen
PRINTS IMPHPHTASES UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IMP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IMP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K0V3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPR2_RAT UniProtKB/TrEMBL
  A0A8L2Q072_RAT UniProtKB/TrEMBL
  BPNT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-26 Bpnt1  3'(2'), 5'-bisphosphate nucleotidase 1  Bpnt1  bisphosphate 3'-nucleotidase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Bpnt1  bisphosphate 3'-nucleotidase 1      Name updated 1299863 APPROVED
2005-01-20 Bpnt1  3'(2'),5'-bisphosphate nucleotidase    3(2),5-bisphosphate nucleotidase  Name updated 1299863 APPROVED
2002-08-07 Bpnt1  3(2),5-bisphosphate nucleotidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation enzyme activity is dependent on Mg2+ and is inhibited by Ca2+ and Li+ ions 632277