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Gene: Cox15 (cytochrome c oxidase assembly homolog COX15) Rattus norvegicus
Symbol: Cox15
Name: cytochrome c oxidase assembly homolog COX15
RGD ID: 1312043
Description: Predicted to have molecular adaptor activity and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme a biosynthetic process; proton transmembrane transport; and respiratory chain complex IV assembly. Predicted to localize to cytochrome complex; mitochondrial inner membrane; and nucleoplasm. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15); PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; hereditary coproporphyria pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: COX15 cytochrome c oxidase assembly homolog; COX15 homolog; COX15 homolog, cytochrome c oxidase assembly protein; COX15 homolog, cytochrome c oxidase assembly protein (yeast); cytochrome c oxidase assembly homolog 15; cytochrome c oxidase assembly homolog 15 (yeast); LOC309391; MGC124864
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01263,494,850 - 263,511,510 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1263,494,852 - 263,511,505 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01270,939,907 - 270,956,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41247,077,102 - 247,093,757 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11247,191,602 - 247,208,363 (+)NCBI
Celera1238,424,532 - 238,441,036 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cox15
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312043
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.