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Gene: Cox15 (cytochrome c oxidase assembly homolog COX15) Rattus norvegicus
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Symbol: Cox15
Name: cytochrome c oxidase assembly homolog COX15
Description: Predicted to have molecular adaptor activity and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme a biosynthetic process; proton transmembrane transport; and respiratory chain complex IV assembly. Predicted to localize to the cytochrome complex; mitochondrial inner membrane; and nucleoplasm. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15); PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; hereditary coproporphyria pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: COX15 cytochrome c oxidase assembly homolog; COX15 homolog; COX15 homolog, cytochrome c oxidase assembly protein; COX15 homolog, cytochrome c oxidase assembly protein (yeast); cytochrome c oxidase assembly homolog 15; cytochrome c oxidase assembly homolog 15 (yeast); LOC309391; MGC124864
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01263,494,850 - 263,511,510 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1263,494,852 - 263,511,505 (-)Ensembl
Rnor_5.01270,939,907 - 270,956,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41247,077,102 - 247,093,757 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11247,191,602 - 247,208,363 (+)NCBI
Celera1238,424,532 - 238,441,036 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cox15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312043
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.