GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos2 | increases activity | EXP | | 6480464 | CTD | deoxynivalenol results in increased activity of NOS2 protein | PMID:34673182 | Nos2 | multiple interactions | EXP | | 6480464 | CTD | deoxynivalenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] | PMID:21748807 | Nos2 | increases expression | ISO | Nos2 (Mus musculus) | 6480464 | CTD | deoxynivalenol results in increased expression of NOS2 protein | PMID:24937323 PMID:32416088 | Nos2 | increases expression | ISO | NOS2 (Homo sapiens) | 6480464 | CTD | deoxynivalenol results in increased expression of NOS2 mRNA | PMID:25766886 | Nos2 | multiple interactions | ISO | Nos2 (Mus musculus) | 6480464 | CTD | Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein] | PMID:19857559 PMID:32416088 | Nos2 | multiple interactions | ISO | NOS2 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol results in increased ubiquitination of and results in increased degradation of NOS2 protein; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [deoxynivalenol results in increased degradation of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] | PMID:25766886 | | ||||||||||||||||||||||
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