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Gene: Dusp10 (dual specificity phosphatase 10) Rattus norvegicus
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Symbol: Dusp10
Name: dual specificity phosphatase 10
Description: Predicted to have phosphoprotein phosphatase activity and protein kinase binding activity. Involved in negative regulation of oligodendrocyte differentiation and response to organic substance. Predicted to localize to the Golgi apparatus; cytosol; and nuclear speck. Biomarker of pancreatitis. Orthologous to human DUSP10 (dual specificity phosphatase 10); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dual specificity protein phosphatase 10; Mkp-5; Mkp5
Orthologs:
Homo sapiens (human) : DUSP10 (dual specificity phosphatase 10)  HGNC  Alliance
Mus musculus (house mouse) : Dusp10 (dual specificity phosphatase 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp10 (dual specificity phosphatase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP10 (dual specificity phosphatase 10)
Canis lupus familiaris (dog) : DUSP10 (dual specificity phosphatase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp10 (dual specificity phosphatase 10)
Sus scrofa (pig) : DUSP10 (dual specificity phosphatase 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013104,284,660 - 104,321,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13104,284,660 - 104,321,455 (+)Ensembl
Rnor_5.013108,932,784 - 108,969,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413100,022,421 - 100,059,539 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113100,211,469 - 100,248,572 (+)NCBI
Celera1395,137,681 - 95,175,173 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dusp10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310844
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.