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Gene: Dusp10 (dual specificity phosphatase 10) Mus musculus
Symbol: Dusp10
Name: dual specificity phosphatase 10
Description: Exhibits MAP kinase phosphatase activity. Involved in several processes, including negative regulation of epithelium regeneration; negative regulation of protein phosphorylation; and negative regulation of respiratory burst involved in inflammatory response. Predicted to localize to the Golgi apparatus; cytosol; and nuclear speck. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DUSP10 (dual specificity phosphatase 10); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610306G15Rik; AI158871; dual specificity protein phosphatase 10; MAP kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; MKP-5; MKP5
Homo sapiens (human) : DUSP10 (dual specificity phosphatase 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dusp10 (dual specificity phosphatase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp10 (dual specificity phosphatase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP10 (dual specificity phosphatase 10)
Canis lupus familiaris (dog) : DUSP10 (dual specificity phosphatase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp10 (dual specificity phosphatase 10)
Sus scrofa (pig) : DUSP10 (dual specificity phosphatase 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1184,013,302 - 184,075,636 (+)Ensembl
GRCm381184,034,381 - 184,075,636 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371185,858,340 - 185,899,515 (+)NCBIGRCm37mm9NCBIm37
MGSCv361185,735,717 - 185,776,892 (+)NCBImm8
Celera1190,994,534 - 191,035,736 (+)NCBICelera
Cytogenetic Map1 H5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dusp10
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321980
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.