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Gene: Dusp10 (dual specificity phosphatase 10) Mus musculus
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Symbol: Dusp10
Name: dual specificity phosphatase 10
Description: Exhibits MAP kinase phosphatase activity. Involved in several processes, including negative regulation of epithelium regeneration; negative regulation of protein phosphorylation; and negative regulation of respiratory burst involved in inflammatory response. Predicted to localize to the Golgi apparatus; cytosol; and nuclear speck. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DUSP10 (dual specificity phosphatase 10); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610306G15Rik; AI158871; dual specificity protein phosphatase 10; MAP kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; MKP-5; MKP5
Orthologs:
Homo sapiens (human) : DUSP10 (dual specificity phosphatase 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dusp10 (dual specificity phosphatase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp10 (dual specificity phosphatase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP10 (dual specificity phosphatase 10)
Canis lupus familiaris (dog) : DUSP10 (dual specificity phosphatase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp10 (dual specificity phosphatase 10)
Sus scrofa (pig) : DUSP10 (dual specificity phosphatase 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1184,013,302 - 184,075,636 (+)Ensembl
GRCm381184,034,381 - 184,075,636 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371185,858,340 - 185,899,515 (+)NCBIGRCm37mm9NCBIm37
MGSCv361185,735,717 - 185,776,892 (+)NCBImm8
Celera1190,994,534 - 191,035,736 (+)NCBICelera
Cytogenetic Map1 H5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dusp10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321980
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.