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Gene: DUSP10 (dual specificity phosphatase 10) Homo sapiens
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Symbol: DUSP10
Name: dual specificity phosphatase 10
Description: Exhibits phosphoprotein phosphatase activity and protein kinase binding activity. Involved in negative regulation of protein phosphorylation; peptidyl-threonine dephosphorylation; and positive regulation of regulatory T cell differentiation. Localizes to the Golgi apparatus; cytosol; and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dual specificity phosphatase MKP-5; dual specificity protein phosphatase 10; map kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; MKP-5; MKP5; serine/threonine specific protein phosphatase
Orthologs:
Mus musculus (house mouse) : Dusp10 (dual specificity phosphatase 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dusp10 (dual specificity phosphatase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp10 (dual specificity phosphatase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP10 (dual specificity phosphatase 10)
Canis lupus familiaris (dog) : DUSP10 (dual specificity phosphatase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp10 (dual specificity phosphatase 10)
Sus scrofa (pig) : DUSP10 (dual specificity phosphatase 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,701,420 - 221,742,176 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371221,874,764 - 221,916,204 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,941,389 - 219,982,084 (-)NCBINCBI36hg18NCBI36
Celera1195,094,721 - 195,135,415 (-)NCBI
Cytogenetic Map1q41NCBI
HuRef1192,550,111 - 192,590,870 (-)NCBIHuRef
CHM1_11223,147,247 - 223,188,015 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on DUSP10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321979
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.