DUSP10 (dual specificity phosphatase 10) - Rat Genome Database

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Gene: DUSP10 (dual specificity phosphatase 10) Homo sapiens
Analyze
Symbol: DUSP10
Name: dual specificity phosphatase 10
RGD ID: 1321979
HGNC Page HGNC:3065
Description: Enables phosphoprotein phosphatase activity and protein kinase binding activity. Involved in negative regulation of JNK cascade; negative regulation of p38MAPK cascade; and positive regulation of regulatory T cell differentiation. Located in cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: dual specificity phosphatase MKP-5; dual specificity protein phosphatase 10; map kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; MKP-5; MKP5; serine/threonine specific protein phosphatase
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,701,424 - 221,742,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,701,424 - 221,742,089 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,874,766 - 221,915,431 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,941,389 - 219,982,084 (-)NCBINCBI36Build 36hg18NCBI36
Celera1195,094,721 - 195,135,415 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1192,550,111 - 192,590,870 (-)NCBIHuRef
CHM1_11223,147,249 - 223,188,013 (-)NCBICHM1_1
T2T-CHM13v2.01220,941,255 - 220,981,921 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-demecolcine  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-nitropyrene  (EXP)
15-acetyldeoxynivalenol  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (EXP)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (EXP)
2-palmitoylglycerol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
8-bromo-3',5'-cyclic GMP  (EXP)
9-cis-retinoic acid  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-4-oxoretinoic acid  (EXP)
all-trans-retinoic acid  (EXP)
amiodarone  (EXP)
andrographolide  (EXP)
aristolochic acid A  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP)
avobenzone  (EXP)
belinostat  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
boron nitride  (EXP)
cadmium atom  (EXP)
calcitriol  (EXP)
CGP 52608  (EXP)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
crotonaldehyde  (EXP)
curcumin  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (EXP)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
entinostat  (EXP)
epoxiconazole  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (EXP)
ethylparaben  (EXP)
febuxostat  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (EXP)
gamma-hexachlorocyclohexane  (EXP)
gentamycin  (ISO)
gingerol  (EXP)
glyphosate  (EXP)
isotretinoin  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
mercury dibromide  (EXP)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (EXP)
methylisothiazolinone  (EXP)
methylmercury chloride  (EXP)
methylseleninic acid  (EXP)
microcystin-LR  (ISO)
N-methylformamide  (ISO)
nickel atom  (EXP)
nickel sulfate  (EXP)
orphenadrine  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (EXP)
phenylmercury acetate  (EXP)
pioglitazone  (EXP)
pirinixic acid  (EXP)
potassium chromate  (EXP)
rac-lactic acid  (EXP)
resveratrol  (EXP)
rotenone  (ISO)
SB 431542  (EXP)
serpentine asbestos  (EXP)
sertraline  (EXP)
sevoflurane  (ISO)
silicon dioxide  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sodium chromate  (EXP)
sulforaphane  (EXP)
sunitinib  (EXP)
tamibarotene  (EXP)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
troglitazone  (EXP)
urethane  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
vincristine  (EXP)
zinc atom  (EXP)
zinc protoporphyrin  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA,IEA)
cytosol  (IBA,IDA)
nucleoplasm  (IDA)
nucleus  (IDA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mechanisms and functions of p38 MAPK signalling. Cuadrado A and Nebreda AR, Biochem J. 2010 Aug 1;429(3):403-17. doi: 10.1042/BJ20100323.
2. Map kinase phosphatases (MKP's) are early responsive genes during induction of cerulein hyperstimulation pancreatitis. Hofken T, etal., Biochem Biophys Res Commun. 2000 Sep 24;276(2):680-5.
3. Regulation of MAP kinases by MAP kinase phosphatases. Kondoh K and Nishida E, Biochim Biophys Acta. 2007 Aug;1773(8):1227-37. Epub 2006 Dec 8.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Zhang Y, etal., Nature. 2004 Aug 12;430(7001):793-7.
Additional References at PubMed
PMID:9571625   PMID:9628821   PMID:10391943   PMID:10597297   PMID:11060451   PMID:11157753   PMID:11359773   PMID:12477932   PMID:15342556   PMID:15489334   PMID:16166642   PMID:16288922  
PMID:16341674   PMID:16565220   PMID:16710414   PMID:16806267   PMID:17151092   PMID:17400920   PMID:17681939   PMID:18029348   PMID:18314537   PMID:19913121   PMID:20379614   PMID:20628086  
PMID:20936779   PMID:20972440   PMID:21487011   PMID:21873635   PMID:21900206   PMID:21988832   PMID:22245064   PMID:22375048   PMID:22387553   PMID:22467874   PMID:22711061   PMID:23233447  
PMID:23275563   PMID:23872954   PMID:23936387   PMID:23993976   PMID:24531476   PMID:24836286   PMID:24975273   PMID:25436638   PMID:25772234   PMID:25973098   PMID:26733232   PMID:27432908  
PMID:27880917   PMID:28065597   PMID:28514442   PMID:28674078   PMID:28675297   PMID:29986742   PMID:30333178   PMID:31122150   PMID:31202710   PMID:31483681   PMID:32296183   PMID:32814053  
PMID:32843541   PMID:33232789   PMID:33961781   PMID:34187934   PMID:34782469   PMID:35488020   PMID:37387540  


Genomics

Comparative Map Data
DUSP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,701,424 - 221,742,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,701,424 - 221,742,089 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,874,766 - 221,915,431 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,941,389 - 219,982,084 (-)NCBINCBI36Build 36hg18NCBI36
Celera1195,094,721 - 195,135,415 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1192,550,111 - 192,590,870 (-)NCBIHuRef
CHM1_11223,147,249 - 223,188,013 (-)NCBICHM1_1
T2T-CHM13v2.01220,941,255 - 220,981,921 (-)NCBIT2T-CHM13v2.0
Dusp10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,766,575 - 183,807,833 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1183,745,499 - 183,807,833 (+)EnsemblGRCm39 Ensembl
GRCm381184,034,381 - 184,075,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,013,302 - 184,075,636 (+)EnsemblGRCm38mm10GRCm38
MGSCv371185,858,340 - 185,899,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361185,735,717 - 185,776,892 (+)NCBIMGSCv36mm8
Celera1190,994,534 - 191,035,736 (+)NCBICelera
Cytogenetic Map1H5NCBI
cM Map188.2NCBI
Dusp10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81398,145,317 - 98,183,304 (+)NCBIGRCr8
mRatBN7.21395,613,716 - 95,651,716 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1395,614,292 - 95,651,716 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1398,119,436 - 98,156,836 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01399,519,471 - 99,556,878 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01396,701,597 - 96,739,011 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013104,284,660 - 104,321,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13104,284,660 - 104,321,455 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013108,932,784 - 108,969,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413100,022,421 - 100,059,539 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113100,211,469 - 100,248,572 (+)NCBI
Celera1395,137,681 - 95,175,173 (+)NCBICelera
Cytogenetic Map13q26NCBI
Dusp10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555202,339,521 - 2,372,400 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555202,338,548 - 2,371,591 (+)NCBIChiLan1.0ChiLan1.0
DUSP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2127,661,873 - 27,704,123 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1127,617,737 - 27,666,286 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01197,293,039 - 197,333,828 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11202,366,333 - 202,407,020 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1202,367,318 - 202,404,720 (-)Ensemblpanpan1.1panPan2
DUSP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13816,196,354 - 16,233,640 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3816,196,635 - 16,231,315 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3816,250,735 - 16,289,545 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03816,240,595 - 16,279,420 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3816,239,677 - 16,279,370 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13816,247,106 - 16,285,251 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03816,596,161 - 16,634,244 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03816,889,953 - 16,928,100 (-)NCBIUU_Cfam_GSD_1.0
Dusp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934455,431,439 - 55,471,755 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936650679,647 - 720,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936650679,650 - 718,867 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1010,866,448 - 10,905,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11010,866,446 - 10,905,852 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21012,978,113 - 13,015,967 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DUSP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1257,790,969 - 7,833,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl257,792,913 - 7,834,346 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660558,050,257 - 8,091,701 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dusp10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248354,750,077 - 4,782,249 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248354,751,651 - 4,783,916 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DUSP10
17 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q41(chr1:215206760-222004068)x1 copy number loss See cases [RCV000050298] Chr1:215206760..222004068 [GRCh38]
Chr1:215380103..222177410 [GRCh37]
Chr1:213446726..220244033 [NCBI36]
Chr1:1q41		 pathogenic
GRCh38/hg38 1q32.3-44(chr1:214023812-248918469)x3 copy number gain See cases [RCV000050981] Chr1:214023812..248918469 [GRCh38]
Chr1:214197155..249212668 [GRCh37]
Chr1:212263778..247179291 [NCBI36]
Chr1:1q32.3-44		 pathogenic
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3 copy number gain See cases [RCV000051857] Chr1:187143981..224299417 [GRCh38]
Chr1:187113113..224487119 [GRCh37]
Chr1:185379736..222553742 [NCBI36]
Chr1:1q31.1-42.11		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:209646207-248931113)x3 copy number gain See cases [RCV000051861] Chr1:209646207..248931113 [GRCh38]
Chr1:209819552..249225312 [GRCh37]
Chr1:207886175..247191935 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q41(chr1:215447347-221971832)x3 copy number gain See cases [RCV000051874] Chr1:215447347..221971832 [GRCh38]
Chr1:215620690..222145174 [GRCh37]
Chr1:213687313..220211797 [NCBI36]
Chr1:1q41		 pathogenic
GRCh38/hg38 1q41-42.13(chr1:221519280-228862141)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053955]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053955]|See cases [RCV000053955] Chr1:221519280..228862141 [GRCh38]
Chr1:221692622..228997888 [GRCh37]
Chr1:219759245..227064511 [NCBI36]
Chr1:1q41-42.13		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:209963625-248918469)x3 copy number gain See cases [RCV000134979] Chr1:209963625..248918469 [GRCh38]
Chr1:210136970..249212668 [GRCh37]
Chr1:208203593..247179291 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q41(chr1:220673535-223683512)x1 copy number loss See cases [RCV000135795] Chr1:220673535..223683512 [GRCh38]
Chr1:220846877..223871214 [GRCh37]
Chr1:218913500..221937837 [NCBI36]
Chr1:1q41		 pathogenic
GRCh38/hg38 1q32.1-42.12(chr1:204764914-225408698)x3 copy number gain See cases [RCV000142054] Chr1:204764914..225408698 [GRCh38]
Chr1:204734042..225596400 [GRCh37]
Chr1:203000665..223663023 [NCBI36]
Chr1:1q32.1-42.12		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:207346642-248930485)x3 copy number gain See cases [RCV000143727] Chr1:207346642..248930485 [GRCh38]
Chr1:207519987..249224684 [GRCh37]
Chr1:205586610..247191307 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q41(chr1:215206760-222004068)x1 copy number loss See cases [RCV000148255] Chr1:215206760..222004068 [GRCh38]
Chr1:215380103..222177410 [GRCh37]
Chr1:213446726..220244033 [NCBI36]
Chr1:1q41		 pathogenic
GRCh37/hg19 1q31.3-42.13(chr1:197811907-228997888)x3 copy number gain See cases [RCV000240137] Chr1:197811907..228997888 [GRCh37]
Chr1:1q31.3-42.13		 pathogenic
Single allele deletion Loeys-Dietz syndrome 4 [RCV000210452] Chr1:215588712..222145072 [GRCh37]
Chr1:1q41		 pathogenic
Single allele deletion Usher syndrome [RCV000505151] Chr1:216066818..222607612 [GRCh38]
Chr1:216240159..222780953 [GRCh37]
Chr1:1q41		 likely pathogenic
GRCh37/hg19 1q31.3-44(chr1:195483439-249213000)x3 copy number gain See cases [RCV000449172] Chr1:195483439..249213000 [GRCh37]
Chr1:1q31.3-44		 pathogenic
GRCh37/hg19 1q41-44(chr1:214697099-249224684)x3 copy number gain See cases [RCV000449210] Chr1:214697099..249224684 [GRCh37]
Chr1:1q41-44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q41-44(chr1:218252551-249224684)x3 copy number gain not provided [RCV000684700] Chr1:218252551..249224684 [GRCh37]
Chr1:1q41-44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1q41-42.11(chr1:219734913-224104993)x1 copy number loss not provided [RCV001005174] Chr1:219734913..224104993 [GRCh37]
Chr1:1q41-42.11		 pathogenic
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3 copy number gain not provided [RCV000845852] Chr1:182388773..249111240 [GRCh37]
Chr1:1q25.3-44		 pathogenic
GRCh37/hg19 1q32.2-44(chr1:210152794-249218992)x3 copy number gain See cases [RCV001194578] Chr1:210152794..249218992 [GRCh37]
Chr1:1q32.2-44		 pathogenic
GRCh37/hg19 1q41(chr1:219379258-222049547)x3 copy number gain not provided [RCV000848714] Chr1:219379258..222049547 [GRCh37]
Chr1:1q41		 uncertain significance
GRCh37/hg19 1q41-43(chr1:219916966-239004378)x3 copy number gain not provided [RCV001005175] Chr1:219916966..239004378 [GRCh37]
Chr1:1q41-43		 pathogenic
GRCh37/hg19 1q32.1-44(chr1:204045948-249218992)x3 copy number gain See cases [RCV001007407] Chr1:204045948..249218992 [GRCh37]
Chr1:1q32.1-44		 pathogenic
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44		 uncertain significance
Single allele deletion Loeys-Dietz syndrome 4 [RCV001837015] Chr1:215199578..223035427 [GRCh37]
Chr1:1q41		 pathogenic
GRCh37/hg19 1q41-42.13(chr1:221303919-227461343) copy number gain not specified [RCV002052845] Chr1:221303919..227461343 [GRCh37]
Chr1:1q41-42.13		 pathogenic
GRCh37/hg19 1q31.3-44(chr1:197867914-249224684)x3 copy number gain See cases [RCV002287837] Chr1:197867914..249224684 [GRCh37]
Chr1:1q31.3-44		 pathogenic
NM_007207.6(DUSP10):c.295G>T (p.Ala99Ser) single nucleotide variant Inborn genetic diseases [RCV003260312] Chr1:221739450 [GRCh38]
Chr1:221912792 [GRCh37]
Chr1:1q41		 uncertain significance
GRCh37/hg19 1q41(chr1:221833606-222245603)x1 copy number loss not provided [RCV002474610] Chr1:221833606..222245603 [GRCh37]
Chr1:1q41		 uncertain significance
GRCh37/hg19 1q41-42.12(chr1:221325488-225804228)x1 copy number loss not provided [RCV002474859] Chr1:221325488..225804228 [GRCh37]
Chr1:1q41-42.12		 uncertain significance
NM_007207.6(DUSP10):c.1444G>T (p.Val482Leu) single nucleotide variant Inborn genetic diseases [RCV002884057] Chr1:221702417 [GRCh38]
Chr1:221875759 [GRCh37]
Chr1:1q41		 uncertain significance
GRCh38/hg38 1q32.2-42.13(chr1:228006998-228061271)x2 copy number loss Orofacial cleft 2 [RCV002481175] Chr1:228006998..228061271 [GRCh38]
Chr1:1q32.2-42.13		 association
NM_007207.6(DUSP10):c.1184A>C (p.Glu395Ala) single nucleotide variant Inborn genetic diseases [RCV002902513] Chr1:221702677 [GRCh38]
Chr1:221876019 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.895G>A (p.Gly299Ser) single nucleotide variant Inborn genetic diseases [RCV002738384] Chr1:221706383 [GRCh38]
Chr1:221879725 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.589G>A (p.Ala197Thr) single nucleotide variant Inborn genetic diseases [RCV002853518] Chr1:221739156 [GRCh38]
Chr1:221912498 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.371C>A (p.Thr124Lys) single nucleotide variant Inborn genetic diseases [RCV002788573] Chr1:221739374 [GRCh38]
Chr1:221912716 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.1090G>A (p.Glu364Lys) single nucleotide variant Inborn genetic diseases [RCV002855039] Chr1:221706188 [GRCh38]
Chr1:221879530 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.319G>A (p.Gly107Arg) single nucleotide variant Inborn genetic diseases [RCV002813501] Chr1:221739426 [GRCh38]
Chr1:221912768 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.1034G>A (p.Arg345Gln) single nucleotide variant Inborn genetic diseases [RCV002769465] Chr1:221706244 [GRCh38]
Chr1:221879586 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.338C>T (p.Pro113Leu) single nucleotide variant Inborn genetic diseases [RCV002792896] Chr1:221739407 [GRCh38]
Chr1:221912749 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.896G>T (p.Gly299Val) single nucleotide variant Inborn genetic diseases [RCV002668275] Chr1:221706382 [GRCh38]
Chr1:221879724 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.328A>G (p.Thr110Ala) single nucleotide variant Inborn genetic diseases [RCV002792765] Chr1:221739417 [GRCh38]
Chr1:221912759 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.122G>A (p.Ser41Asn) single nucleotide variant Inborn genetic diseases [RCV002878590] Chr1:221739623 [GRCh38]
Chr1:221912965 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.608G>A (p.Arg203Gln) single nucleotide variant Inborn genetic diseases [RCV003210622] Chr1:221739137 [GRCh38]
Chr1:221912479 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.503C>T (p.Pro168Leu) single nucleotide variant Inborn genetic diseases [RCV003304274] Chr1:221739242 [GRCh38]
Chr1:221912584 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.551A>G (p.Asn184Ser) single nucleotide variant Inborn genetic diseases [RCV003343012] Chr1:221739194 [GRCh38]
Chr1:221912536 [GRCh37]
Chr1:1q41		 uncertain significance
NM_007207.6(DUSP10):c.1354A>T (p.Met452Leu) single nucleotide variant Inborn genetic diseases [RCV003385227] Chr1:221702507 [GRCh38]
Chr1:221875849 [GRCh37]
Chr1:1q41		 uncertain significance
GRCh37/hg19 1q41(chr1:214853277-222111742)x1 copy number loss not provided [RCV003484033] Chr1:214853277..222111742 [GRCh37]
Chr1:1q41		 pathogenic
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR21hsa-miR-21-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22387553

Predicted Target Of
Summary Value
Count of predictions:1185
Count of miRNA genes:366
Interacting mature miRNAs:379
Transcripts:ENST00000323825, ENST00000366899, ENST00000468085, ENST00000477026, ENST00000494642, ENST00000544095
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-76391  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,875,167 - 221,875,314UniSTSGRCh37
Build 361219,941,790 - 219,941,937RGDNCBI36
Celera1195,095,121 - 195,095,268RGD
Cytogenetic Map1q41UniSTS
HuRef1192,550,514 - 192,550,661UniSTS
TNG Radiation Hybrid Map1110007.0UniSTS
GeneMap99-GB4 RH Map1710.27UniSTS
NCBI RH Map11899.1UniSTS
SHGC-76392  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,875,506 - 221,875,646UniSTSGRCh37
Build 361219,942,129 - 219,942,269RGDNCBI36
Celera1195,095,460 - 195,095,600RGD
Cytogenetic Map1q41UniSTS
HuRef1192,550,853 - 192,550,993UniSTS
TNG Radiation Hybrid Map1110011.0UniSTS
GeneMap99-GB4 RH Map1710.8UniSTS
GeneMap99-GB4 RH Map1711.98UniSTS
Whitehead-RH Map1902.4UniSTS
AL033755  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,880,924 - 221,881,092UniSTSGRCh37
Build 361219,947,547 - 219,947,715RGDNCBI36
Celera1195,100,878 - 195,101,046RGD
Cytogenetic Map1q41UniSTS
HuRef1192,556,272 - 192,556,440UniSTS
SHGC-142873  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,914,093 - 221,914,390UniSTSGRCh37
Build 361219,980,716 - 219,981,013RGDNCBI36
Celera1195,134,047 - 195,134,344RGD
Cytogenetic Map1q41UniSTS
HuRef1192,589,447 - 192,589,744UniSTS
TNG Radiation Hybrid Map1109982.0UniSTS
RH69568  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,874,905 - 221,875,118UniSTSGRCh37
Build 361219,941,528 - 219,941,741RGDNCBI36
Celera1195,094,859 - 195,095,072RGD
Cytogenetic Map1q41UniSTS
HuRef1192,550,252 - 192,550,465UniSTS
GeneMap99-GB4 RH Map1708.93UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 627 255 404 413 832 349 909 374 320 71 459 446 80 1 163 430 1
Low 1808 2671 1314 209 1100 114 3446 1754 3394 337 992 1163 94 1041 2357 3 2
Below cutoff 4 65 8 2 17 2 1 65 18 11 5 2 1 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_111939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_111940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017000147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047442942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047442948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054334004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA431025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB026436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF179212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI220242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI261880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK022513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL590966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG720911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP222019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ000769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ082194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ223632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC192022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC192024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000366899   ⟹   ENSP00000355866
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,701,424 - 221,742,089 (-)Ensembl
RefSeq Acc Id: ENST00000468085   ⟹   ENSP00000483812
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,701,483 - 221,736,900 (-)Ensembl
RefSeq Acc Id: ENST00000477026   ⟹   ENSP00000482935
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,702,150 - 221,742,089 (-)Ensembl
RefSeq Acc Id: ENST00000494642   ⟹   ENSP00000480008
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,702,427 - 221,711,816 (-)Ensembl
RefSeq Acc Id: NM_007207   ⟹   NP_009138
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,701,424 - 221,742,089 (-)NCBI
GRCh371221,874,764 - 221,916,204 (-)NCBI
Build 361219,941,389 - 219,982,084 (-)NCBI Archive
HuRef1192,550,111 - 192,590,870 (-)ENTREZGENE
CHM1_11223,147,247 - 223,188,015 (-)NCBI
T2T-CHM13v2.01220,941,255 - 220,981,921 (-)NCBI
Sequence:
RefSeq Acc Id: NR_111939
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,701,424 - 221,736,900 (-)NCBI
CHM1_11223,147,247 - 223,182,739 (-)NCBI
T2T-CHM13v2.01220,941,255 - 220,976,732 (-)NCBI
Sequence:
RefSeq Acc Id: NR_111940
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,701,424 - 221,742,089 (-)NCBI
CHM1_11223,147,247 - 223,188,015 (-)NCBI
T2T-CHM13v2.01220,941,255 - 220,981,921 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017000147   ⟹   XP_016855636
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,735,435 - 221,742,089 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047442942   ⟹   XP_047298898
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,735,435 - 221,742,089 (-)NCBI
RefSeq Acc Id: XM_047442948   ⟹   XP_047298904
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,701,424 - 221,714,435 (-)NCBI
RefSeq Acc Id: XM_054334002   ⟹   XP_054189977
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01220,975,302 - 220,981,921 (-)NCBI
RefSeq Acc Id: XM_054334003   ⟹   XP_054189978
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01220,975,302 - 220,981,921 (-)NCBI
RefSeq Acc Id: XM_054334004   ⟹   XP_054189979
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01220,941,255 - 220,954,265 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_009138   ⟸   NM_007207
- UniProtKB: Q6GSI4 (UniProtKB/Swiss-Prot),   D3DTB4 (UniProtKB/Swiss-Prot),   Q9H9Z5 (UniProtKB/Swiss-Prot),   Q9Y6W6 (UniProtKB/Swiss-Prot),   Q6IAR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016855636   ⟸   XM_017000147
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000482935   ⟸   ENST00000477026
RefSeq Acc Id: ENSP00000483812   ⟸   ENST00000468085
RefSeq Acc Id: ENSP00000480008   ⟸   ENST00000494642
RefSeq Acc Id: ENSP00000355866   ⟸   ENST00000366899
RefSeq Acc Id: XP_047298904   ⟸   XM_047442948
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047298898   ⟸   XM_047442942
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054189979   ⟸   XM_054334004
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054189977   ⟸   XM_054334002
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054189978   ⟸   XM_054334003
- Peptide Label: isoform X2
Protein Domains
Rhodanese   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y6W6-F1-model_v2 AlphaFold Q9Y6W6 1-482 view protein structure

Promoters
RGD ID:6785079
Promoter ID:HG_KWN:7427
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat,   Lymphoblastoid
Transcripts:OTTHUMT00000090719
Position:
Human AssemblyChrPosition (strand)Source
Build 361219,951,296 - 219,952,502 (-)MPROMDB
RGD ID:6785076
Promoter ID:HG_KWN:7428
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:NM_144728
Position:
Human AssemblyChrPosition (strand)Source
Build 361219,976,826 - 219,978,132 (-)MPROMDB
RGD ID:6814444
Promoter ID:HG_XEF:733
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_001031044
Position:
Human AssemblyChrPosition (strand)Source
Build 361219,980,331 - 219,980,831 (-)MPROMDB
RGD ID:6785077
Promoter ID:HG_KWN:7429
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_144729,   OTTHUMT00000090716
Position:
Human AssemblyChrPosition (strand)Source
Build 361219,981,926 - 219,983,117 (-)MPROMDB
RGD ID:6859044
Promoter ID:EPDNEW_H2686
Type:initiation region
Name:DUSP10_1
Description:dual specificity phosphatase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,742,089 - 221,742,149EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3065 AgrOrtholog
COSMIC DUSP10 COSMIC
Ensembl Genes ENSG00000143507 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000366899 ENTREZGENE
  ENST00000366899.4 UniProtKB/Swiss-Prot
  ENST00000468085 ENTREZGENE
  ENST00000468085.5 UniProtKB/TrEMBL
  ENST00000477026.5 UniProtKB/TrEMBL
  ENST00000494642.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000143507 GTEx
HGNC ID HGNC:3065 ENTREZGENE
Human Proteome Map DUSP10 Human Proteome Map
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MKP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodanese-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:11221 UniProtKB/Swiss-Prot
NCBI Gene 11221 ENTREZGENE
OMIM 608867 OMIM
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE 10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DSPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodanese UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA27520 PharmGKB
PRINTS ADSPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAPKPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DSPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52821 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0B4J2F5_HUMAN UniProtKB/TrEMBL
  D3DTB4 ENTREZGENE
  DUS10_HUMAN UniProtKB/Swiss-Prot
  Q6GSI4 ENTREZGENE
  Q6IAR2 ENTREZGENE, UniProtKB/TrEMBL
  Q9H9Z5 ENTREZGENE
  Q9Y6W6 ENTREZGENE
UniProt Secondary D3DTB4 UniProtKB/Swiss-Prot
  Q6GSI4 UniProtKB/Swiss-Prot
  Q9H9Z5 UniProtKB/Swiss-Prot