Dusp10 (dual specificity phosphatase 10)

Gene: Dusp10 (dual specificity phosphatase 10) Ictidomys tridecemlineatus

Analyze

Symbol:

Dusp10

Name:

dual specificity phosphatase 10

RGD ID:

12508265

Description:

ENCODES a protein that exhibits JUN kinase binding (inferred); MAP kinase phosphatase activity (inferred); MAP kinase tyrosine phosphatase activity (inferred); INVOLVED IN negative regulation of JNK cascade (ortholog); negative regulation of oligodendrocyte differentiation (ortholog); negative regulation of respiratory burst involved in inflammatory response (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH Experimental Autoimmune Encephalomyelitis (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dual specificity protein phosphatase 10

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	55,431,439 - 55,471,755 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936650	679,647 - 720,038 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936650	679,650 - 718,867 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Autoimmune Encephalomyelitis (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

Inflammation (ISO)

Loeys-Dietz syndrome 4 (ISO)

pancreatitis (ISO)

parathyroid carcinoma (ISO)

Usher syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of epithelial cell migration (IEA)

negative regulation of epithelial cell proliferation (IEA)

negative regulation of epithelium regeneration (IEA)

negative regulation of ERK1 and ERK2 cascade (IEA)

negative regulation of JNK cascade (IEA,ISO)

negative regulation of oligodendrocyte differentiation (ISO)

negative regulation of p38MAPK cascade (IEA)

negative regulation of respiratory burst involved in inflammatory response (IEA,ISO)

negative regulation of stress-activated MAPK cascade (IEA,ISO)

oligodendrocyte differentiation (IEA,ISO)

positive regulation of regulatory T cell differentiation (IEA)

regulation of adaptive immune response (IEA,ISO)

regulation of brown fat cell differentiation (IEA,ISO)

regulation of innate immune response (IEA,ISO)

response to lipopolysaccharide (IEA,ISO)

stress-activated MAPK cascade (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

JUN kinase binding (IEA)

MAP kinase phosphatase activity (IEA)

MAP kinase tyrosine phosphatase activity (IEA)

MAP kinase tyrosine/serine/threonine phosphatase activity (IEA)

mitogen-activated protein kinase p38 binding (IEA)

myosin phosphatase activity (IEA)

phosphatase activity (IEA)

phosphoprotein phosphatase activity (IEA)

protein binding (ISO)

protein tyrosine/threonine phosphatase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

c-Jun N-terminal kinases MAPK signaling pathway (ISO)

p38 MAPK signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Dusp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	55,431,439 - 55,471,755 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936650	679,647 - 720,038 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936650	679,650 - 718,867 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DUSP10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	221,701,424 - 221,742,089 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	221,701,424 - 221,742,089 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	221,874,766 - 221,915,431 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	219,941,389 - 219,982,084 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	195,094,721 - 195,135,415 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	192,550,111 - 192,590,870 (-)	NCBI		HuRef
CHM1_1	1	223,147,249 - 223,188,013 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	220,941,255 - 220,981,921 (-)	NCBI		T2T-CHM13v2.0

Dusp10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	183,766,575 - 183,807,833 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	183,745,499 - 183,807,833 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	184,034,381 - 184,075,636 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	184,013,302 - 184,075,636 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	185,858,340 - 185,899,515 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	185,735,717 - 185,776,892 (+)	NCBI		MGSCv36	mm8
Celera	1	190,994,534 - 191,035,736 (+)	NCBI		Celera
Cytogenetic Map	1	H5	NCBI
cM Map	1	88.2	NCBI

Dusp10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	98,145,317 - 98,183,304 (+)	NCBI		GRCr8
mRatBN7.2	13	95,613,716 - 95,651,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	95,614,292 - 95,651,716 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	98,119,436 - 98,156,836 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	99,519,471 - 99,556,878 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	96,701,597 - 96,739,011 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	104,284,660 - 104,321,455 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	104,284,660 - 104,321,455 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	108,932,784 - 108,969,913 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	100,022,421 - 100,059,539 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	100,211,469 - 100,248,572 (+)	NCBI
Celera	13	95,137,681 - 95,175,173 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

Dusp10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955520	2,339,521 - 2,372,400 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955520	2,338,548 - 2,371,591 (+)	NCBI	ChiLan1.0	ChiLan1.0

DUSP10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	27,661,873 - 27,704,123 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	27,617,737 - 27,666,286 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	197,293,039 - 197,333,828 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	202,366,333 - 202,407,020 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	202,367,318 - 202,404,720 (-)	Ensembl	panpan1.1		panPan2

DUSP10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	16,196,354 - 16,233,640 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	16,196,635 - 16,231,315 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	16,250,735 - 16,289,545 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	16,240,595 - 16,279,420 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	16,239,677 - 16,279,370 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	16,247,106 - 16,285,251 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	16,596,161 - 16,634,244 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	16,889,953 - 16,928,100 (-)	NCBI		UU_Cfam_GSD_1.0

DUSP10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	10,866,448 - 10,905,857 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	10,866,446 - 10,905,852 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	12,978,113 - 13,015,967 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DUSP10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	7,790,969 - 7,833,485 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	7,792,913 - 7,834,346 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	8,050,257 - 8,091,701 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dusp10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	4,750,077 - 4,782,249 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	4,751,651 - 4,783,916 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005335853	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000011660 ⟹ ENSSTOP00000010463

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936650	679,647 - 720,038 (+)	Ensembl

RefSeq Acc Id:

XM_005335853 ⟹ XP_005335910

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	55,431,439 - 55,471,755 (+)	NCBI
SpeTri2.0	NW_004936650	679,650 - 718,867 (+)	NCBI

Sequence:

show sequence

ACGGAGGAGCCACAGCAGACTCTTGAGTTCTTCTTGAATTGCCAGTTTTCAGCCTCCTCATGCC
TCCGTCTCCTTTAGACGACAGGGTAGTAGTGGCACTATCTAGGCCCGTCCGACCTCAGGATCTC
AACCTTTGTTTAGACTCTAGCTATCTTGGCTCTGCCACTCCAGGCAGCAATAGACACCGTCCTG
TCATCGCCACCACAGTCGTGTCCCTCAAGGCTGCGAATCTGACGTATATGCCCTCATCCAGCGG
CTCTGCCCGCTCCCTGAATTGTGGATGCAGCAGTGCCAGCTGCTGCACTGTGGCAACCTACGAC
AAGGACAATCAGGCCCAAACCCAAGCCATCGCTGCTGGCACTGCCACCACCGCCATTGGAACCT
CTACCACCTGCCCTGCTAACCAGATGGTCAACAACAATGAGAATACAGGCTCTTTAAGTCCATC
AGGTGGGGTGGGCAGCCCTGTGTCAGGGACCCCCAAGCAGCTAGCCAGCATCAAAATAATCTAC
CCCAATGACCTGGCAAAGAAGATGACCAAATGCAGCAAGAGTCACCTGCCAAGCCAGGGCCCTG
TCATCATTGACTGCAGGCCCTTCATGGAGTACAACAAAAGTCACATCCAAGGAGCTGTCCATAT
TAACTGTGCCGATAAGATCAGCCGGCGGAGACTGCAGCAAGGCAAGATCACTGTTCTAGACTTG
ATTTCCTGTAGGGAAGGCAAGGACTCTTTCAAGAGGATCTTTTCCAAAGAAATTATAGTTTATG
ATGAGAATACCAATGAACCGAGCCGTGTGATGCCCTCCCAGCCGCTTCACATAGTCCTCGAGTC
CCTGAAGAGAGAAGGCAAAGAACCTCTGGTGTTGAAAGGTGGACTTAGTAGTTTTAAGCAGAAC
CATGAAAACCTCTGTGACAACTCCCTCCAGCTCCAAGAGTGCCGGGAGGTGGGGGGCGGTGCAT
CTGCGGCCTCGAGCTTGCTACCTCAGTCTGTCCCCACCACCCCTGACATCGAGAATGCAGAGCT
GACGCCCATCCTGCCCTTCCTGTTCCTTGGCAATGAGCAGGACGCTCAGGACCTGGACACCATG
CAGCGGCTGAACATTGGCTATGTCATCAACGTCACCACTCACCTTCCCCTCTACCACTACGAGA
AAGGTCTCTTCAACTACAAGCGGCTGCCGGCCACCGACAGCAACAAGCAGAACCTGCGGCAGTA
CTTTGAAGAGGCTTTTGAGTTCATTGAGGAAGCTCATCAGTGTGGGAAGGGGCTTCTCATCCAC
TGCCAGGCCGGAGTGTCCCGCTCTGCCACCATTGTCATCGCCTACCTGATGAAGCACACACGGA
TGACCATGACTGATGCTTACAAATTTGTCAAAGGCAAACGACCAATTATTTCTCCAAATCTTAA
CTTCATGGGGCAGTTGCTGGAGTTTGAGGAAGACCTAAACAATGGTGTGACGCCACGCATCCTT
ACGCCAAAGCTGATGGGTGTGGAGACGGTCGTGTGACCGTGCTCAGGGTGGAAAGGATTGCTGC
TCTCCTTTGGGGGGCAAAAAAGGAAGGAGGATGGGTTCTGGGTCCCCCCCCCTTTTTTTTTCCT
TTTTTTTTAGTTGGGGGTAAAGTTTGTGAATGGAAACAAACTTGTTTAAAGACTTTATTTTTAA
CAAGTGTGAGAAGACTATAACTTTTGATGCCATTGAGATTTACTTCCCACAAACTGACAAAGCA
GGGAGGTTCAAGAGGTCATTTTTTTTTTTAAAGCCAACAATGAAAATATAATAAAACTTGTTTC
TCCCCCTTTTCCTTTTAAGCTTTTTGTAGAGTTTATGACTAAATAGTCTGTGCAGGTTCATAGA
CCTAAGATCCCATATACACCATTTTAAAAGAACCAAAAGTAAGTAGAAAAGACATTGGATCATG
AGGACCTAGGAGCCTACCTGGGCCATCCATATAGGAAATAAAAACCCCACCCAACCAAGCCCTG
CTGTGCTCCTTGGTGCAGAGAGAAGATCAGGGCAGCTTGAGTGGTCTAAGAAACCTTCGCGTAT
TCTTTAAAGAAATAGAGAATAGTGTTTTATGCTCTGGACTTTTCTTTCCCCCCGCTCTCTGGGT
TGAAGAAACTTTTTGAAACAACAACAAGGAACGACTGACCACTATACCATAGGCCTTCACTGGC
TCTTGTGCAATAATATGGTGTTTTGAGTGTGCAAACAAGTTTAGAGCTGGCAAGTGAATGATAG
ACAAATAGTGCAAAATTGCCAGCTTGGAGGTAGAAAGAAATTCAACAAAACCAATTACTTTCCT
TCCCACCTTTTCCTTTTTTTTTTTTTTTTGGGTTTTATTCTGGTTATAGTGCCATAAACCTTGT
TACATATGGTATATAGAATGTAAAAAAAAAAAAAATGACAAAAATTTATTTAAAAATATTTTTC
GCAAAAAAAAAGCAAAAACAAACTTTGTGTGTTTCTGTTGATTGTGTAAAAATTTATTTTCATT
ATATAAATGAAACT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005335910	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000010463.3
GenBank Protein	KAG3258048	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005335910 ⟸ XM_005335853

- UniProtKB:

I3MHR9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSATPGSNRHRPVIATTVVSLKAANLTYMPSS
SGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTATTAIGTSTTCPANQMVNNNENTGSLS
PSGGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAV
HINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENTNEPSRVMPSQPLHIVL
ESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGASAASSLLPQSVPTTPDIENA
ELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR
QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN
LNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV

hide sequence

RefSeq Acc Id:

ENSSTOP00000010463 ⟸ ENSSTOT00000011660

Protein Domains

Rhodanese Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000011662	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000011660.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.250.10	UniProtKB/TrEMBL
	3.90.190.10	UniProtKB/TrEMBL
InterPro	Dual-sp_phosphatase_cat-dom	UniProtKB/TrEMBL
	MKP	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	Rhodanese-like_dom	UniProtKB/TrEMBL
	Rhodanese-like_dom_sf	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_dom	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL_dom	UniProtKB/TrEMBL
NCBI Gene	Dusp10	ENTREZGENE
PANTHER	DUAL SPECIFICITY PROTEIN PHOSPHATASE	UniProtKB/TrEMBL
	DUAL SPECIFICITY PROTEIN PHOSPHATASE 10	UniProtKB/TrEMBL
Pfam	DSPc	UniProtKB/TrEMBL
	Rhodanese	UniProtKB/TrEMBL
PRINTS	ADSPHPHTASE	UniProtKB/TrEMBL
	MAPKPHPHTASE	UniProtKB/TrEMBL
PROSITE	RHODANESE_3	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL	UniProtKB/TrEMBL
SMART	DSPc	UniProtKB/TrEMBL
	RHOD	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52799	UniProtKB/TrEMBL
	SSF52821	UniProtKB/TrEMBL
UniProt	I3MHR9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations