GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | deoxynivalenol results in increased phosphorylation of MAPK1 protein | PMID:17707346 PMID:20633634 | Mapk1 | increases phosphorylation | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | deoxynivalenol results in increased phosphorylation of MAPK1 protein | PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:15976193 PMID:16009389 PMID:16424113 PMID:18502741 PMID:23352502 PMID:23811945 PMID:24937323 PMID:32416088 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | [deoxynivalenol results in increased phosphorylation of MAPK1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA] | PMID:17707346 PMID:18006205 PMID:18485432 PMID:19360757 | Mapk1 | multiple interactions | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein] | PMID:14690764 PMID:15570035 PMID:15772366 PMID:16009389 PMID:32416088 | | ||||||||||||||||||||||
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