CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: nickel ion
Accession: CHEBI:60248
browse the term
Definition: A nickel atom having a net electric charge.
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Hmbs
hydroxymethylbilane synthase
decreases activity
EXP
Nickel ion decreases activity of purified Hmbs protein
RGD
PMID:6732900
RGD:25394584
NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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Aass
aminoadipate-semialdehyde synthase
decreases expression
ISO
nickel sulfate results in decreased expression of AASS mRNA
CTD
PMID:22714537
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
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Abca5
ATP binding cassette subfamily A member 5
increases expression
ISO
nickel sulfate results in increased expression of ABCA5 mRNA
CTD
PMID:22714537
NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
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Abca6
ATP binding cassette subfamily A member 6
decreases expression
ISO
nickel sulfate results in decreased expression of ABCA6 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
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Abcc1
ATP binding cassette subfamily C member 1
increases expression
ISO
nickel sulfate results in increased expression of ABCC1 mRNA
CTD
PMID:16780908
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
ISO
nickel sulfate results in increased expression of ABCC3 mRNA
CTD
PMID:16314067 PMID:22714537
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abhd10
abhydrolase domain containing 10, depalmitoylase
decreases expression
ISO
nickel sulfate results in decreased expression of ABHD10 mRNA
CTD
PMID:17374397
NCBI chr11:55,081,273...55,095,044
Ensembl chr11:55,081,049...55,107,866
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Abhd12
abhydrolase domain containing 12, lysophospholipase
decreases expression
ISO
nickel sulfate results in decreased expression of ABHD12 mRNA
CTD
PMID:22714537
NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564
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Abhd17a
abhydrolase domain containing 17A, depalmitoylase
increases expression
ISO
nickel sulfate results in increased expression of ABHD17A mRNA
CTD
PMID:22714537
NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
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Abi3bp
ABI family member 3 binding protein
increases expression
ISO
nickel sulfate results in increased expression of ABI3BP mRNA
CTD
PMID:22714537
NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
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Ablim1
actin-binding LIM protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of ABLIM1 mRNA
CTD
PMID:22714537
NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969
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Abraxas1
abraxas 1, BRCA1 A complex subunit
decreases expression
ISO
nickel sulfate results in decreased expression of ABRAXAS1 mRNA
CTD
PMID:22714537
NCBI chr14:8,796,281...8,810,625
Ensembl chr14:8,796,266...8,810,622
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Acbd7
acyl-CoA binding domain containing 7
decreases expression
ISO
nickel sulfate results in decreased expression of ACBD7 mRNA
CTD
PMID:22714537
NCBI chr17:74,903,936...74,909,977
Ensembl chr17:74,903,177...74,905,811
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Aco1
aconitase 1
decreases expression
ISO
nickel sulfate results in decreased expression of ACO1 mRNA
CTD
PMID:16780908
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Aco2
aconitase 2
increases expression
ISO
nickel sulfate results in increased expression of ACO2 mRNA
CTD
PMID:18651567
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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Acot13
acyl-CoA thioesterase 13
increases expression
ISO
nickel sulfate results in increased expression of ACOT13 mRNA
CTD
PMID:22714537
NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851
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Acot2
acyl-CoA thioesterase 2
increases expression
ISO
nickel sulfate results in increased expression of ACOT2 mRNA
CTD
PMID:16780908
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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Acot4
acyl-CoA thioesterase 4
decreases expression
ISO
nickel sulfate results in decreased expression of ACOT4 mRNA
CTD
PMID:22714537
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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Acox2
acyl-CoA oxidase 2
increases expression
ISO
nickel sulfate results in increased expression of ACOX2 mRNA
CTD
PMID:16314067
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Acsl5
acyl-CoA synthetase long-chain family member 5
decreases expression
ISO
nickel sulfate results in decreased expression of ACSL5 mRNA
CTD
PMID:22714537
NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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Acss2
acyl-CoA synthetase short-chain family member 2
increases expression
ISO
nickel sulfate results in increased expression of ACSS2 mRNA
CTD
PMID:22714537
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Acta1
actin, alpha 1, skeletal muscle
increases expression
ISO
nickel sulfate results in increased expression of ACTA1 mRNA
CTD
PMID:16166746
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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Actc1
actin, alpha, cardiac muscle 1
decreases expression
ISO
nickel sulfate results in decreased expression of ACTC1 mRNA
CTD
PMID:16100012
NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
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Actg2
actin gamma 2, smooth muscle
increases expression
ISO
nickel sulfate results in increased expression of ACTG2 mRNA
CTD
PMID:16780908
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Acvr1
activin A receptor type 1
increases expression
ISO
nickel sulfate results in increased expression of ACVR1 mRNA
CTD
PMID:22714537
NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
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Acvr1b
activin A receptor type 1B
increases expression
ISO
nickel sulfate results in increased expression of ACVR1B mRNA
CTD
PMID:18651567
NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
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Ada
adenosine deaminase
increases expression
ISO
nickel sulfate results in increased expression of ADA mRNA
CTD
PMID:22714537
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
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Adam12
ADAM metallopeptidase domain 12
decreases expression
ISO
nickel sulfate results in decreased expression of ADAM12 mRNA
CTD
PMID:22714537
NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
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Adam19
ADAM metallopeptidase domain 19
decreases expression
ISO
nickel sulfate results in decreased expression of ADAM19 mRNA
CTD
PMID:16166746
NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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Adam32
ADAM metallopeptidase domain 32
decreases expression
ISO
nickel sulfate results in decreased expression of ADAM32 mRNA
CTD
PMID:22714537
NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161
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Adam8
ADAM metallopeptidase domain 8
increases expression
ISO
nickel sulfate results in increased expression of ADAM8 mRNA
CTD
PMID:16166746
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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Adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
decreases expression
ISO
nickel sulfate results in decreased expression of ADAMTS12 mRNA
CTD
PMID:22714537
NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
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Adamts3
ADAM metallopeptidase with thrombospondin type 1, motif 3
decreases expression
ISO
nickel sulfate results in decreased expression of ADAMTS3 mRNA
CTD
PMID:22714537
NCBI chr14:18,231,128...18,437,771
Ensembl chr14:18,231,165...18,435,556
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Adamtsl1
ADAMTS-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of ADAMTSL1 mRNA
CTD
PMID:22714537
NCBI chr 5:99,964,406...100,919,786
Ensembl chr 5:99,964,486...100,918,384
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Adamtsl3
ADAMTS-like 3
decreases expression
ISO
nickel sulfate results in decreased expression of ADAMTSL3 mRNA
CTD
PMID:22714537
NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986
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Adck2
aarF domain containing kinase 2
increases expression
ISO
nickel sulfate results in increased expression of ADCK2 mRNA
CTD
PMID:22714537
NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608
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Adcy7
adenylate cyclase 7
decreases expression
ISO
nickel sulfate results in decreased expression of ADCY7 mRNA
CTD
PMID:16780908
NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
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Add3
adducin 3
decreases expression
ISO
nickel sulfate results in decreased expression of ADD3 mRNA
CTD
PMID:18651567
NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
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Adgrg1
adhesion G protein-coupled receptor G1
increases expression
ISO
nickel sulfate results in increased expression of ADGRG1 mRNA
CTD
PMID:22714537
NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
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Adm
adrenomedullin
increases expression decreases expression
ISO
nickel sulfate results in increased expression of ADM mRNA nickel sulfate results in decreased expression of ADM mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adora2a
adenosine A2a receptor
increases expression
ISO
nickel sulfate results in increased expression of ADORA2A mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Adora2b
adenosine A2B receptor
increases expression
ISO
nickel sulfate results in increased expression of ADORA2B mRNA
CTD
PMID:16314067
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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Afap1l2
actin filament associated protein 1-like 2
decreases expression
ISO
nickel sulfate results in decreased expression of AFAP1L2 mRNA
CTD
PMID:22714537
NCBI chr 1:255,964,238...256,060,828
Ensembl chr 1:255,964,238...256,060,820
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Aff3
ALF transcription elongation factor 3
increases expression
ISO
nickel sulfate results in increased expression of AFF3 mRNA
CTD
PMID:22714537
NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247
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Agbl5
AGBL carboxypeptidase 5
increases expression
ISO
nickel sulfate results in increased expression of AGBL5 mRNA
CTD
PMID:22714537
NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738
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Agmat
agmatinase
decreases expression
ISO
nickel sulfate results in decreased expression of AGMAT mRNA
CTD
PMID:22714537
NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
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Agtpbp1
ATP/GTP binding carboxypeptidase 1
decreases expression
ISO
nickel sulfate results in decreased expression of AGTPBP1 mRNA
CTD
PMID:22714537
NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869
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Ahcyl1
adenosylhomocysteinase-like 1
affects expression
ISO
nickel sulfate affects the expression of AHCYL1 mRNA
CTD
PMID:18202158
NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
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Ahdc1
AT hook, DNA binding motif, containing 1
increases expression
ISO
nickel sulfate results in increased expression of AHDC1 mRNA
CTD
PMID:18651567
NCBI chr 5:145,228,228...145,294,170
Ensembl chr 5:145,228,227...145,294,145
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Ahnak2
AHNAK nucleoprotein 2
increases expression
ISO
nickel sulfate results in increased expression of AHNAK2 mRNA
CTD
PMID:18651567
NCBI chr 6:131,830,668...131,876,311
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Akap11
A-kinase anchoring protein 11
decreases expression
ISO
nickel sulfate results in decreased expression of AKAP11 mRNA
CTD
PMID:22714537
NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
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Akr1b1
aldo-keto reductase family 1 member B1
increases expression
ISO
nickel sulfate results in increased expression of AKR1B1 mRNA
CTD
PMID:20566472
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
nickel sulfate results in increased expression of AKR1B10 mRNA
CTD
PMID:20566472
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
nickel sulfate results in increased expression of AKR1C1 mRNA
CTD
PMID:20566472
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c3
aldo-keto reductase family 1, member C3
increases expression
ISO
nickel sulfate results in increased expression of AKR1C3 mRNA
CTD
PMID:20566472
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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Akr1e2
aldo-keto reductase family 1, member E2
decreases expression
ISO
nickel sulfate results in decreased expression of AKR1E2 mRNA
CTD
PMID:22714537
NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441
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Akt1
AKT serine/threonine kinase 1
increases phosphorylation
ISO
nickel sulfate results in increased phosphorylation of AKT1 protein
CTD
PMID:23445166
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alcam
activated leukocyte cell adhesion molecule
increases expression
ISO
nickel sulfate results in increased expression of ALCAM mRNA
CTD
PMID:16780908
NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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Aldh1l2
aldehyde dehydrogenase 1 family, member L2
decreases expression
ISO
nickel sulfate results in decreased expression of ALDH1L2 mRNA
CTD
PMID:22714537
NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776
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Aldh3a2
aldehyde dehydrogenase 3 family, member A2
increases expression
ISO
nickel sulfate results in increased expression of ALDH3A2 mRNA
CTD
PMID:22714537
NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
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Aldh5a1
aldehyde dehydrogenase 5 family, member A1
increases expression
ISO
nickel sulfate results in increased expression of ALDH5A1 mRNA
CTD
PMID:22714537
NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
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Aldoc
aldolase, fructose-bisphosphate C
increases expression
ISO
nickel sulfate results in increased expression of ALDOC mRNA
CTD
PMID:17382205 PMID:22714537
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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Alg5
ALG5, dolichyl-phosphate beta-glucosyltransferase
decreases expression
ISO
nickel sulfate results in decreased expression of ALG5 mRNA
CTD
PMID:22714537
NCBI chr 2:138,936,998...138,951,228
Ensembl chr 2:138,936,993...138,951,216
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Alox5ap
arachidonate 5-lipoxygenase activating protein
decreases expression
ISO
nickel sulfate results in decreased expression of ALOX5AP mRNA
CTD
PMID:16780908
NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
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Alpk2
alpha-kinase 2
decreases expression
ISO
nickel sulfate results in decreased expression of ALPK2 mRNA
CTD
PMID:22714537
NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
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Alyref
Aly/REF export factor
increases expression
ISO
nickel sulfate results in increased expression of THOC4 mRNA
CTD
PMID:22714537
NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069
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Ampd3
adenosine monophosphate deaminase 3
affects expression
ISO
nickel sulfate affects the expression of AMPD3 mRNA
CTD
PMID:18202158
NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
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Angptl4
angiopoietin-like 4
multiple interactions increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of ANGPTL4 mRNA nickel sulfate results in increased expression of ANGPTL4 mRNA
CTD
PMID:16166746 PMID:17382205 PMID:18832182
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Ankh
ANKH inorganic pyrophosphate transport regulator
increases expression
ISO
nickel sulfate results in increased expression of ANKH mRNA
CTD
PMID:22714537
NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187
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Ankrd1
ankyrin repeat domain 1
decreases expression
ISO
nickel sulfate results in decreased expression of ANKRD1 mRNA
CTD
PMID:22714537
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Ankrd6
ankyrin repeat domain 6
increases expression
ISO
nickel sulfate results in increased expression of ANKRD6 mRNA
CTD
PMID:22714537
NCBI chr 5:47,197,981...47,343,183
Ensembl chr 5:47,202,873...47,343,090
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Ano2
anoctamin 2
decreases expression
ISO
nickel sulfate results in decreased expression of ANO2 mRNA
CTD
PMID:22714537
NCBI chr 4:158,514,200...158,855,639
Ensembl chr 4:158,496,014...158,855,651
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Anpep
alanyl aminopeptidase, membrane
decreases expression
ISO
nickel sulfate results in decreased expression of ANPEP mRNA
CTD
PMID:16166746
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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Antxr1
ANTXR cell adhesion molecule 1
increases expression
ISO
nickel sulfate results in increased expression of ANTXR1 mRNA
CTD
PMID:22714537
NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232
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Antxr2
ANTXR cell adhesion molecule 2
increases expression decreases expression
ISO
nickel sulfate results in increased expression of ANTXR2 mRNA nickel sulfate results in decreased expression of ANTXR2 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094
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Anxa1
annexin A1
increases expression
ISO
nickel sulfate results in increased expression of ANXA1 mRNA
CTD
PMID:16314067
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Anxa2
annexin A2
increases expression
ISO
nickel sulfate results in increased expression of ANXA2 mRNA
CTD
PMID:16314067
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Anxa3
annexin A3
decreases expression
ISO
nickel sulfate results in decreased expression of ANXA3 mRNA
CTD
PMID:22714537
NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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Aoc1
amine oxidase, copper containing 1
increases expression
ISO
nickel sulfate results in increased expression of AOC1 mRNA
CTD
PMID:16780908
NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
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Aox1
aldehyde oxidase 1
decreases expression
ISO
nickel sulfate results in decreased expression of AOX1 mRNA
CTD
PMID:22714537
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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Ap1ar
adaptor-related protein complex 1 associated regulatory protein
decreases expression
ISO
nickel sulfate results in decreased expression of AP1AR mRNA
CTD
PMID:22714537
NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013
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Apba2
amyloid beta precursor protein binding family A member 2
increases expression
ISO
nickel sulfate results in increased expression of APBA2 mRNA
CTD
PMID:22714537
NCBI chr 1:118,053,270...118,286,858
Ensembl chr 1:118,103,219...118,285,699
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Apmap
adipocyte plasma membrane associated protein
decreases expression
ISO
nickel sulfate results in decreased expression of APMAP mRNA
CTD
PMID:22714537
NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341
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Apoe
apolipoprotein E
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of APOE mRNA nickel sulfate results in increased expression of APOE mRNA
CTD
PMID:16780908
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Aqp3
aquaporin 3 (Gill blood group)
decreases expression
ISO
nickel sulfate results in decreased expression of AQP3 mRNA
CTD
PMID:16780908 PMID:20713136
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Aqp9
aquaporin 9
decreases expression
ISO
nickel sulfate results in decreased expression of AQP9 mRNA
CTD
PMID:18651567
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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Ar
androgen receptor
increases expression
ISO
nickel sulfate results in increased expression of AR mRNA
CTD
PMID:22714537
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
decreases expression
ISO
nickel sulfate results in decreased expression of ARAP2 mRNA
CTD
PMID:22714537
NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154
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Areg
amphiregulin
increases expression decreases expression
ISO
nickel sulfate results in increased expression of AREG mRNA nickel sulfate results in decreased expression of AREG mRNA
CTD
PMID:16166746 PMID:18651567 PMID:22714537
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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Arfip2
ADP-ribosylation factor interacting protein 2
increases expression
ISO
nickel sulfate results in increased expression of ARFIP2 mRNA
CTD
PMID:18651567
NCBI chr 1:159,974,255...159,980,398
Ensembl chr 1:159,974,201...159,980,336
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Arg2
arginase 2
increases expression
ISO
nickel sulfate results in increased expression of ARG2 mRNA
CTD
PMID:16314067
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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Arhgap17
Rho GTPase activating protein 17
decreases expression
ISO
nickel sulfate results in decreased expression of ARHGAP17 mRNA
CTD
PMID:17374397
NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
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Arhgap18
Rho GTPase activating protein 18
increases expression
ISO
nickel sulfate results in increased expression of ARHGAP18 mRNA
CTD
PMID:22714537
NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
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Arhgap42
Rho GTPase activating protein 42
decreases expression
ISO
nickel sulfate results in decreased expression of ARHGAP42 mRNA
CTD
PMID:22714537
NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870
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Arhgap44
Rho GTPase activating protein 44
increases expression
ISO
nickel sulfate results in increased expression of ARHGAP44 mRNA
CTD
PMID:22714537
NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297
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Arhgap5
Rho GTPase activating protein 5
decreases expression
ISO
nickel sulfate results in decreased expression of ARHGAP5 mRNA
CTD
PMID:22714537
NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
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Arhgef9
Cdc42 guanine nucleotide exchange factor 9
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ARHGEF9 mRNA
CTD
PMID:31734292
NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513
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Arl10
ADP-ribosylation factor like GTPase 10
decreases expression
ISO
nickel sulfate results in decreased expression of ARL10 mRNA
CTD
PMID:22714537
NCBI chr17:10,030,213...10,038,625
Ensembl chr17:10,030,213...10,038,703
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Arl4c
ADP ribosylation factor like GTPase 4C
increases expression
ISO
nickel sulfate results in increased expression of ARL4C mRNA
CTD
PMID:17374397 PMID:18651567
NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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Armcx1
armadillo repeat containing, X-linked 1
decreases expression
ISO
nickel sulfate results in decreased expression of ARMCX1 mRNA
CTD
PMID:22714537
NCBI chr X:97,898,969...97,902,874
Ensembl chr X:97,898,883...97,903,299
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Armcx2
armadillo repeat containing, X-linked 2
decreases expression
ISO
nickel sulfate results in decreased expression of ARMCX2 mRNA
CTD
PMID:22714537
NCBI chr X:97,980,662...97,985,523
Ensembl chr X:97,980,660...97,985,552
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Armcx4
armadillo repeat containing, X-linked 4
decreases expression
ISO
nickel sulfate results in decreased expression of ARMCX4 mRNA
CTD
PMID:22714537
NCBI chr X:97,860,526...97,870,912
Ensembl chr X:97,860,629...97,870,912
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Arnt
aryl hydrocarbon receptor nuclear translocator
affects localization
ISO
nickel sulfate affects the localization of ARNT protein
CTD
PMID:17382205
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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Arnt2
aryl hydrocarbon receptor nuclear translocator 2
increases expression
ISO
nickel sulfate results in increased expression of ARNT2 mRNA
CTD
PMID:22714537
NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
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Arpc2
actin related protein 2/3 complex, subunit 2
increases expression
ISO
nickel sulfate results in increased expression of ARPC2 mRNA
CTD
PMID:16780908
NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
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Arpc4
actin related protein 2/3 complex, subunit 4
increases expression
ISO
nickel sulfate results in increased expression of ARPC4 mRNA
CTD
PMID:18651567
NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
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Arrb1
arrestin, beta 1
increases expression
ISO
nickel sulfate results in increased expression of ARRB1 mRNA
CTD
PMID:22714537
NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
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Asah1
N-acylsphingosine amidohydrolase 1
decreases expression
ISO
nickel sulfate results in decreased expression of ASAH1 mRNA
CTD
PMID:16780908
NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
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Asgr1
asialoglycoprotein receptor 1
decreases expression
ISO
nickel sulfate results in decreased expression of ASGR1 mRNA
CTD
PMID:16780908
NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
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Asgr2
asialoglycoprotein receptor 2
decreases expression
ISO
nickel sulfate results in decreased expression of ASGR2 mRNA
CTD
PMID:16780908
NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
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Asmtl
acetylserotonin O-methyltransferase-like
increases expression
ISO
nickel sulfate results in increased expression of ASMTL mRNA
CTD
PMID:22714537
NCBI chr12:16,315,335...16,318,083
Ensembl chr12:16,315,414...16,318,080
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Ass1
argininosuccinate synthase 1
increases expression
ISO
nickel sulfate results in increased expression of ASS1 mRNA
CTD
PMID:22714537
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atat1
alpha tubulin acetyltransferase 1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ATAT1 mRNA
CTD
PMID:31734292
NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964
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Atf3
activating transcription factor 3
increases expression
ISO
nickel sulfate results in increased expression of ATF3 mRNA
CTD
PMID:16314067
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atf6
activating transcription factor 6
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of ATF6 mRNA
CTD
PMID:31734292
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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Atl1
atlastin GTPase 1
decreases expression
ISO
nickel sulfate results in decreased expression of ATL1 mRNA
CTD
PMID:22714537
NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204
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Atl3
atlastin GTPase 3
decreases expression
ISO
nickel sulfate results in decreased expression of ATL3 mRNA
CTD
PMID:22714537
NCBI chr 1:204,680,958...204,727,360
Ensembl chr 1:204,680,968...204,723,354
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Atp11a
ATPase phospholipid transporting 11A
decreases expression
ISO
nickel sulfate results in decreased expression of ATP11A mRNA
CTD
PMID:22714537
NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640
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Atp1b1
ATPase Na+/K+ transporting subunit beta 1
decreases expression
ISO
nickel sulfate results in decreased expression of ATP1B1 mRNA
CTD
PMID:16100012
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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Atp1b3
ATPase Na+/K+ transporting subunit beta 3
increases expression decreases expression
ISO
nickel sulfate results in increased expression of ATP1B3 mRNA nickel sulfate results in decreased expression of ATP1B3 mRNA
CTD
PMID:16780908 PMID:18651567
NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
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Atp2b4
ATPase plasma membrane Ca2+ transporting 4
decreases expression
ISO
nickel sulfate results in decreased expression of ATP2B4 mRNA
CTD
PMID:22714537
NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
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Atp6v1a
ATPase H+ transporting V1 subunit A
decreases expression
ISO
nickel sulfate results in decreased expression of ATP6V1A mRNA
CTD
PMID:18651567
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Atp8b2
ATPase phospholipid transporting 8B2
decreases expression
ISO
nickel sulfate results in decreased expression of ATP8B2 mRNA
CTD
PMID:22714537
NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883
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Atp9a
ATPase phospholipid transporting 9A (putative)
increases expression
ISO
nickel sulfate results in increased expression of ATP9A mRNA
CTD
PMID:22714537
NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818
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Atrn
attractin
decreases expression
ISO
nickel sulfate results in decreased expression of ATRN mRNA
CTD
PMID:22714537
NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
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Atxn1
ataxin 1
increases expression
ISO
nickel sulfate results in increased expression of ATXN1 mRNA
CTD
PMID:22714537
NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
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Atxn7l1
ataxin 7-like 1
increases expression
ISO
nickel sulfate results in increased expression of ATXN7L1 mRNA
CTD
PMID:22714537
NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320
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Auts2
activator of transcription and developmental regulator AUTS2
increases expression
ISO
nickel sulfate results in increased expression of AUTS2 mRNA
CTD
PMID:22714537
NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416
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Azin1
antizyme inhibitor 1
decreases expression
ISO
nickel sulfate results in decreased expression of AZIN1 mRNA
CTD
PMID:17374397
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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B3gat1
beta-1,3-glucuronyltransferase 1
decreases expression
ISO
nickel sulfate results in decreased expression of B3GAT1 mRNA
CTD
PMID:16780908
NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
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B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
increases expression
ISO
nickel sulfate results in increased expression of B3GNT5 mRNA
CTD
PMID:22714537
NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166
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B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
increases expression
ISO
nickel sulfate results in increased expression of B4GALNT1 mRNA
CTD
PMID:22714537
NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190
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Bach1
BTB domain and CNC homolog 1
increases expression
ISO
nickel sulfate results in increased expression of BACH1 mRNA
CTD
PMID:18651567
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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Baiap2l1
BAR/IMD domain containing adaptor protein 2 like 1
increases expression
ISO
nickel sulfate results in increased expression of BAIAP2L1 mRNA
CTD
PMID:22714537
NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
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Bak1
BCL2-antagonist/killer 1
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein] nickel sulfate results in increased expression of BAK1 mRNA; nickel sulfate results in increased expression of BAK1 protein
CTD
PMID:28296042
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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Bambi
BMP and activin membrane-bound inhibitor
increases expression
ISO
nickel sulfate results in increased expression of BAMBI mRNA
CTD
PMID:20146380
NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO
sesamin inhibits the reaction [nickel sulfate results in increased expression of BAX protein] pyrazolanthrone inhibits the reaction [nickel sulfate results in increased expression of BAX protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of BAX protein] nickel sulfate results in increased expression of BAX mRNA; nickel sulfate results in increased expression of BAX protein
CTD
PMID:23317420 PMID:35499276
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bbs5
Bardet-Biedl syndrome 5
increases expression
ISO
nickel sulfate results in increased expression of BBS5 mRNA
CTD
PMID:22714537
NCBI chr 3:54,410,429...54,431,831
Ensembl chr 3:54,410,775...54,431,829
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Bcar1
BCAR1 scaffold protein, Cas family member
decreases expression
ISO
nickel sulfate results in decreased expression of BCAR1 mRNA
CTD
PMID:16166746
NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
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Bcl11a
BCL11 transcription factor A
decreases expression
ISO
nickel sulfate results in decreased expression of BCL11A mRNA
CTD
PMID:18651567
NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
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Bcl2
BCL2, apoptosis regulator
increases expression decreases expression multiple interactions
ISO EXP
nickel sulfate results in increased expression of BCL2 protein nickel sulfate results in decreased expression of BCL2 protein sesamin inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein] nickel sulfate results in decreased expression of BCL2 mRNA; nickel sulfate results in decreased expression of BCL2 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]
CTD
PMID:21776270 PMID:23317420 PMID:34612572 PMID:35499276
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2a1
BCL2-related protein A1
increases expression
ISO
nickel sulfate results in increased expression of BCL2A1 mRNA
CTD
PMID:16780908
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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Bcl2l1
Bcl2-like 1
increases expression multiple interactions decreases expression
ISO
nickel sulfate results in increased expression of BCL2L1 protein pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of BCL2L1 protein] nickel sulfate results in decreased expression of BCL2L1 mRNA; nickel sulfate results in decreased expression of BCL2L1 protein
CTD
PMID:21776270 PMID:35499276
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bcl2l11
Bcl2-like 11
increases expression
ISO
nickel sulfate results in increased expression of BCL2L11 mRNA
CTD
PMID:17382205
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Bcl9
BCL9, transcription coactivator
increases expression
ISO
nickel sulfate results in increased expression of BCL9 mRNA
CTD
PMID:17382205
NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435
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Bdh1
3-hydroxybutyrate dehydrogenase 1
decreases expression
ISO
nickel sulfate results in decreased expression of BDH1 mRNA
CTD
PMID:22714537
NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
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Bex2
brain expressed X-linked 2
decreases expression
ISO
nickel sulfate results in decreased expression of BEX1 mRNA
CTD
PMID:22714537
NCBI chr X:99,019,847...99,021,375
Ensembl chr X:99,019,000...99,021,503
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Bex4
brain expressed, X-linked 4
decreases expression
ISO
nickel sulfate results in decreased expression of BEX4 mRNA
CTD
PMID:22714537
NCBI chr X:99,131,985...99,133,417
Ensembl chr X:99,131,942...99,133,531
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Bhlhe40
basic helix-loop-helix family, member e40
increases expression
ISO
nickel sulfate results in increased expression of BHLHE40 mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Bicc1
BicC family RNA binding protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of BICC1 mRNA
CTD
PMID:22714537
NCBI chr20:17,449,639...17,686,775
Ensembl chr20:17,449,560...17,686,776
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Bid
BH3 interacting domain death agonist
increases expression
ISO
nickel sulfate results in increased expression of BID mRNA
CTD
PMID:16780908
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Bin1
bridging integrator 1
increases expression
ISO
nickel sulfate results in increased expression of BIN1 mRNA
CTD
PMID:22714537
NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
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Birc2
baculoviral IAP repeat-containing 2
increases expression
ISO
nickel sulfate results in increased expression of BIRC2 mRNA
CTD
PMID:16780908
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc3
baculoviral IAP repeat-containing 3
increases expression
ISO
nickel sulfate results in increased expression of BIRC3 mRNA
CTD
PMID:16780908
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
nickel sulfate affects the localization of and results in increased expression of BIRC5 protein
CTD
PMID:21776270
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bmi1
BMI1 proto-oncogene, polycomb ring finger
decreases expression
ISO
nickel sulfate results in decreased expression of BMI1 mRNA
CTD
PMID:22714537
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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Bmp2
bone morphogenetic protein 2
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of BMP2 mRNA
CTD
PMID:31734292
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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Bmp4
bone morphogenetic protein 4
increases expression
ISO
nickel sulfate results in increased expression of BMP4 mRNA
CTD
PMID:22714537
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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Bmp6
bone morphogenetic protein 6
increases expression
ISO
nickel sulfate results in increased expression of BMP6 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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Bmper
BMP-binding endothelial regulator
decreases expression
ISO
nickel sulfate results in decreased expression of BMPER mRNA
CTD
PMID:22714537
NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
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Bnip3
BCL2 interacting protein 3
increases expression
ISO
nickel sulfate results in increased expression of BNIP3 mRNA
CTD
PMID:17382205
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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Brcc3
BRCA1/BRCA2-containing complex subunit 3
decreases expression
ISO
nickel sulfate results in decreased expression of BRCC3 mRNA
CTD
PMID:22714537
NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
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Brd2
bromodomain containing 2
decreases expression
ISO
nickel sulfate results in decreased expression of BRD2 mRNA
CTD
PMID:18651567
NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
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Bst2
bone marrow stromal cell antigen 2
increases expression
ISO
nickel sulfate results in increased expression of BST2 mRNA
CTD
PMID:18651567
NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
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Btbd2
BTB domain containing 2
increases expression
ISO
nickel sulfate results in increased expression of BTBD2 mRNA
CTD
PMID:22714537
NCBI chr 7:9,058,609...9,075,341
Ensembl chr 7:9,060,788...9,075,344
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Btbd3
BTB domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of BTBD3 mRNA
CTD
PMID:22714537
NCBI chr 3:125,591,427...125,621,660
Ensembl chr 3:125,591,490...125,619,038
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Btg1
BTG anti-proliferation factor 1
increases expression
ISO
nickel sulfate results in increased expression of BTG1 mRNA
CTD
PMID:16780908 PMID:17374397 PMID:22714537
NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression
ISO
nickel sulfate results in decreased expression of BUB1 mRNA
CTD
PMID:17374397
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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C17h10orf67
similar to human chromosome 10 open reading frame 67
decreases expression
ISO
nickel sulfate results in decreased expression of C10ORF67 mRNA
CTD
PMID:22714537
NCBI chr17:82,062,461...82,174,401
Ensembl chr17:82,071,838...82,174,353
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C19h1orf198
similar to human chromosome 1 open reading frame 198
increases expression
ISO
nickel sulfate results in increased expression of C1ORF198 mRNA
CTD
PMID:16780908
NCBI chr19:52,604,060...52,629,436
Ensembl chr19:52,604,060...52,629,436
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C1h19orf33
similar to human chromosome 19 open reading frame 33
decreases expression
ISO
nickel sulfate results in decreased expression of C19ORF33 mRNA
CTD
PMID:22714537
NCBI chr 1:84,549,830...84,550,666
Ensembl chr 1:84,549,831...84,550,664
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C1qa
complement C1q A chain
decreases expression
ISO
nickel sulfate results in decreased expression of C1QA mRNA
CTD
PMID:25673294
NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
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C1qb
complement C1q B chain
decreases expression
ISO
nickel sulfate results in decreased expression of C1QB mRNA
CTD
PMID:16780908
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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C1qc
complement C1q C chain
decreases expression
ISO
nickel sulfate results in decreased expression of C1QC mRNA
CTD
PMID:16780908
NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
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C1ql4
complement C1q like 4
increases expression
ISO
nickel sulfate results in increased expression of C1QL4 mRNA
CTD
PMID:22714537
NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678
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C1r
complement C1r
increases expression
ISO
nickel sulfate results in increased expression of C1R mRNA
CTD
PMID:22714537
NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
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C1s
complement C1s
increases expression
ISO
nickel sulfate results in increased expression of C1S mRNA
CTD
PMID:22714537
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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C3h15orf48
similar to human chromosome 15 open reading frame 48
increases expression
ISO
nickel sulfate results in increased expression of C15ORF48 mRNA
CTD
PMID:25673294
NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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C5
complement C5
affects expression decreases expression
ISO
nickel sulfate affects the expression of HC mRNA nickel sulfate results in decreased expression of HC mRNA
CTD
PMID:12718980 PMID:16166746
NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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C9h6orf132
similar to human chromosome 6 open reading frame 132
decreases expression
ISO
nickel sulfate results in decreased expression of C6ORF132 mRNA
CTD
PMID:22714537
NCBI chr 9:13,524,822...13,561,756
Ensembl chr 9:13,525,395...13,561,585
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Cables1
Cdk5 and Abl enzyme substrate 1
increases expression
ISO
nickel sulfate results in increased expression of CABLES1 mRNA
CTD
PMID:22714537
NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,075,524...3,181,181
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Cachd1
cache domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of CACHD1 mRNA
CTD
PMID:22714537
NCBI chr 5:115,411,833...115,637,312
Ensembl chr 5:115,411,071...115,657,505
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Cacna1i
calcium voltage-gated channel subunit alpha1 I
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of CACNA1I mRNA
CTD
PMID:31734292
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
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Calcrl
calcitonin receptor like receptor
increases expression
ISO
nickel sulfate results in increased expression of CALCRL mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
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Camk1
calcium/calmodulin-dependent protein kinase I
increases expression
ISO
nickel sulfate results in increased expression of CAMK1 mRNA
CTD
PMID:16780908
NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081
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Canx
calnexin
decreases expression
ISO
nickel sulfate results in decreased expression of CANX mRNA
CTD
PMID:16780908
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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Caprin2
caprin family member 2
increases expression
ISO
nickel sulfate results in increased expression of CAPRIN2 mRNA
CTD
PMID:22714537
NCBI chr 4:181,806,105...181,860,754
Ensembl chr 4:181,806,575...181,860,830
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Car13
carbonic anhydrase 13
decreases expression
ISO
nickel sulfate results in decreased expression of CA13 mRNA
CTD
PMID:22714537
NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
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Car2
carbonic anhydrase 2
decreases expression
ISO
nickel sulfate results in decreased expression of CA2 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car9
carbonic anhydrase 9
multiple interactions decreases expression increases expression
ISO
Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of CA9 protein] nickel sulfate results in decreased expression of CA9 mRNA
CTD
PMID:16288478 PMID:22714537
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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Card10
caspase recruitment domain family, member 10
increases expression
ISO
nickel sulfate results in increased expression of CARD10 mRNA
CTD
PMID:18651567
NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
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Carmil1
capping protein regulator and myosin 1 linker 1
increases expression
ISO
nickel sulfate results in increased expression of CARMIL1 mRNA
CTD
PMID:22714537
NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
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Cask
calcium/calmodulin dependent serine protein kinase
decreases expression
ISO
nickel sulfate results in decreased expression of CASK mRNA
CTD
PMID:22714537
NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694
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Casp12
caspase 12
increases expression multiple interactions
EXP
nickel sulfate results in increased expression of CASP12 mRNA; nickel sulfate results in increased expression of CASP12 protein Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]
CTD
PMID:28296042 PMID:34612572
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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Casp3
caspase 3
multiple interactions increases cleavage increases expression decreases expression
ISO EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]]; nickel sulfate inhibits the reaction [Potassium Dichromate results in increased cleavage of and results in increased activity of CASP3 protein]; nickel sulfate results in increased cleavage of and results in increased activity of CASP3 protein; nickel sulfate results in increased expression of and results in increased cleavage of CASP3 protein; Potassium Dichromate inhibits the reaction [nickel sulfate results in increased cleavage of and results in increased activity of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form] nickel sulfate results in increased cleavage of CASP3 protein sesamin inhibits the reaction [nickel sulfate results in increased cleavage of CASP3 protein] Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein] nickel sulfate results in increased expression of CASP3 protein; nickel sulfate results in increased expression of CASP3 protein modified form nickel sulfate results in increased expression of CASP3 mRNA; nickel sulfate results in increased expression of CASP3 protein modified form
CTD
PMID:20493934 PMID:23317420 PMID:28296042 PMID:34612572 PMID:35499276
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
multiple interactions increases expression
EXP ISO
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein] nickel sulfate results in increased expression of CASP9 mRNA; nickel sulfate results in increased expression of CASP9 protein
CTD
PMID:28296042 PMID:34612572
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
increases expression multiple interactions decreases activity increases activity
ISO EXP
nickel sulfate results in increased expression of CAT mRNA naringin inhibits the reaction [nickel sulfate results in decreased activity of CAT protein]; Selenium inhibits the reaction [nickel sulfate results in increased activity of CAT protein]; Zinc inhibits the reaction [nickel sulfate results in increased activity of CAT protein] sesamin inhibits the reaction [nickel sulfate results in decreased activity of CAT protein]
CTD
PMID:15535990 PMID:20566472 PMID:20950607 PMID:23317420 PMID:34612572
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cblb
Cbl proto-oncogene B
increases expression
ISO
nickel sulfate results in increased expression of CBLB mRNA
CTD
PMID:22714537
NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
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Cbr2
carbonyl reductase 2
decreases expression
ISO
nickel sulfate results in decreased expression of CBR2 mRNA
CTD
PMID:16100012
NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
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Cbx2
chromobox 2
increases expression
ISO
nickel sulfate results in increased expression of CBX2 mRNA
CTD
PMID:22714537
NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383
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Ccdc167
coiled-coil domain containing 167
increases expression
ISO
nickel sulfate results in increased expression of CCDC167 mRNA
CTD
PMID:22714537
NCBI chr20:7,763,927...7,782,090
Ensembl chr20:7,751,782...7,781,613
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Ccdc169
coiled-coil domain containing 169
decreases expression
ISO
nickel sulfate results in decreased expression of CCDC169 mRNA
CTD
PMID:22714537
NCBI chr 2:139,321,644...139,351,161
Ensembl chr 2:139,321,670...139,351,161
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Ccdc18
coiled-coil domain containing 18
decreases expression
ISO
nickel sulfate results in decreased expression of CCDC18 mRNA
CTD
PMID:22714537
NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711
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Ccdc3
coiled-coil domain containing 3
increases expression
ISO
nickel sulfate results in increased expression of CCDC3 mRNA
CTD
PMID:22714537
NCBI chr17:73,031,891...73,135,173
Ensembl chr17:73,035,045...73,135,337
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Ccdc68
coiled-coil domain containing 68
increases expression
ISO
nickel sulfate results in increased expression of CCDC68 mRNA
CTD
PMID:22714537
NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119
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Ccdc80
coiled-coil domain containing 80
decreases expression
ISO
nickel sulfate results in decreased expression of CCDC80 mRNA
CTD
PMID:22714537
NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
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Ccdc88c
coiled-coil domain containing 88C
increases expression
ISO
nickel sulfate results in increased expression of CCDC88C mRNA
CTD
PMID:22714537
NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555
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Ccl1
C-C motif chemokine ligand 1
increases expression
ISO
nickel sulfate results in increased expression of CCL1 mRNA
CTD
PMID:11145678
NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
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Ccl11
C-C motif chemokine ligand 11
decreases expression increases expression affects expression
ISO
nickel sulfate results in decreased expression of CCL11 mRNA nickel sulfate results in increased expression of CCL11 mRNA nickel sulfate affects the expression of CCL11 mRNA
CTD
PMID:16166746 PMID:18202158 PMID:18832182
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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Ccl12
C-C motif chemokine ligand 12
decreases expression
ISO
nickel sulfate results in decreased expression of CCL13 mRNA
CTD
PMID:16780908
NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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Ccl17
C-C motif chemokine ligand 17
affects expression increases expression
ISO
nickel sulfate affects the expression of CCL17 mRNA nickel sulfate results in increased expression of CCL17 mRNA
CTD
PMID:16166746 PMID:18202158
NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
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Ccl2
C-C motif chemokine ligand 2
decreases expression increases expression multiple interactions
ISO
nickel sulfate results in decreased expression of CCL2 mRNA nickel sulfate results in increased expression of CCL2 mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of CCL2 mRNA
CTD
PMID:12060402 PMID:15585374 PMID:16100012 PMID:16166746 PMID:16780908 PMID:17374397 PMID:18832182 PMID:20713136 More...
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl20
C-C motif chemokine ligand 20
multiple interactions increases secretion
ISO
IL1A protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]; TNF protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]
CTD
PMID:15679580 PMID:16099135
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl22
C-C motif chemokine ligand 22
affects expression increases expression
ISO
nickel sulfate affects the expression of CCL22 mRNA nickel sulfate results in increased expression of CCL22 mRNA
CTD
PMID:12060402 PMID:16166746 PMID:18202158
NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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Ccl27
C-C motif chemokine ligand 27
increases secretion
ISO
nickel sulfate results in increased secretion of CCL27 protein
CTD
PMID:15679580
NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506
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Ccl28
C-C motif chemokine ligand 28
decreases expression
ISO
nickel sulfate results in decreased expression of CCL28 mRNA
CTD
PMID:22714537
NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
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Ccl3
C-C motif chemokine ligand 3
affects expression increases expression
ISO
nickel sulfate affects the expression of CCL3 mRNA nickel sulfate results in increased expression of CCL3 mRNA
CTD
PMID:15585374 PMID:16780908 PMID:18202158 PMID:19732821
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl4
C-C motif chemokine ligand 4
increases expression increases secretion
ISO
nickel sulfate results in increased expression of CCL4 mRNA; nickel sulfate results in increased expression of CCL4 protein nickel sulfate results in increased secretion of CCL4 protein
CTD
PMID:12060402 PMID:15585374 PMID:16314067 PMID:16780908 PMID:18353026 PMID:20713136 More...
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccl5
C-C motif chemokine ligand 5
affects expression increases secretion
ISO
nickel sulfate affects the expression of CCL5 mRNA nickel sulfate results in increased secretion of CCL5 protein
CTD
PMID:16099135 PMID:18202158
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
nickel sulfate results in increased expression of CCL7 mRNA
CTD
PMID:16166746
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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Ccr1
C-C motif chemokine receptor 1
affects expression
ISO
nickel sulfate affects the expression of CCR1 mRNA
CTD
PMID:18202158
NCBI chr 8:123,556,286...123,561,841
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Ccr2
C-C motif chemokine receptor 2
decreases expression
ISO
nickel sulfate results in decreased expression of CCR2 mRNA
CTD
PMID:17374397
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Ccr6
C-C motif chemokine receptor 6
decreases expression
ISO
nickel sulfate results in decreased expression of CCR6 protein
CTD
PMID:15924226
NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
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Ccr7
C-C motif chemokine receptor 7
affects expression increases expression
ISO
nickel sulfate affects the expression of CCR7 mRNA nickel sulfate results in increased expression of CCR7 mRNA
CTD
PMID:15304089 PMID:16780908 PMID:17374397 PMID:18202158 PMID:21697260
NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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Ccr8
C-C motif chemokine receptor 8
affects expression increases expression
ISO
nickel sulfate affects the expression of CCR8 mRNA nickel sulfate results in increased expression of CCR8 mRNA
CTD
PMID:11145678 PMID:18202158
NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629
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Cd200
Cd200 molecule
decreases expression multiple interactions
ISO EXP
nickel sulfate results in decreased expression of CD200 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CD200 mRNA
CTD
PMID:22714537 PMID:31734292
NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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Cd207
CD207 molecule
multiple interactions decreases expression
ISO
pyrazolanthrone promotes the reaction [nickel sulfate results in decreased expression of CD207 protein]
CTD
PMID:15588916
NCBI chr 4:116,155,229...116,161,587
Ensembl chr 4:116,155,212...116,161,518
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Cd274
CD274 molecule
increases expression decreases expression
ISO
nickel sulfate results in increased expression of CD274 protein nickel sulfate results in decreased expression of CD274 mRNA
CTD
PMID:22714537 PMID:25673294
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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Cd276
Cd276 molecule
increases expression
ISO
nickel sulfate results in increased expression of CD276 mRNA
CTD
PMID:16780908
NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
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Cd36
CD36 molecule
decreases expression
ISO
nickel sulfate results in decreased expression of CD36 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd40
CD40 molecule
multiple interactions increases expression
ISO
BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of CD40 protein]
CTD
PMID:17636246 PMID:25673294
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd68
Cd68 molecule
increases expression
ISO
nickel sulfate results in increased expression of CD68 mRNA
CTD
PMID:22714537
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cd69
Cd69 molecule
increases expression
ISO
nickel sulfate results in increased expression of CD69 mRNA
CTD
PMID:16780908
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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Cd74
CD74 molecule
decreases expression
ISO
nickel sulfate results in decreased expression of CD74 mRNA
CTD
PMID:22714537
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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Cd79a
CD79a molecule
decreases expression
ISO
nickel sulfate results in decreased expression of CD79A mRNA
CTD
PMID:16166746
NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935
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Cd80
Cd80 molecule
increases expression
ISO
nickel sulfate results in increased expression of CD80 protein
CTD
PMID:25673294
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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Cd82
Cd82 molecule
increases expression
ISO
nickel sulfate results in increased expression of CD82 mRNA
CTD
PMID:22714537
NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
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Cd83
CD83 molecule
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of CD83 mRNA; nickel sulfate results in increased expression of CD83 protein BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of CD83 protein]; lipopolysaccharide, E coli O55-B5 promotes the reaction [nickel sulfate results in increased expression of CD83 protein]; TNF protein promotes the reaction [nickel sulfate results in increased expression of CD83 protein]
CTD
PMID:16099135 PMID:16780908 PMID:17636246 PMID:21697260 PMID:25673294
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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Cd86
CD86 molecule
increases expression affects expression multiple interactions
ISO
nickel sulfate results in increased expression of CD86 mRNA; nickel sulfate results in increased expression of CD86 protein nickel sulfate affects the expression of CD86 mRNA Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CD86 protein]; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of CD86 protein]
CTD
PMID:16099135 PMID:16780908 PMID:17374397 PMID:17636246 PMID:18202158 PMID:19033392 PMID:19665512 PMID:19702435 PMID:20417223 PMID:25673294 PMID:29540657 More...
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cd8a
CD8 subunit alpha
increases expression
ISO
nickel sulfate results in increased expression of CD8A mRNA
CTD
PMID:16780908
NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
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Cd99
CD99 molecule (Xg blood group)
increases expression
ISO
nickel sulfate results in increased expression of CD99 mRNA
CTD
PMID:22714537
NCBI chr20:54,418,239...54,422,882
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Cdc25b
cell division cycle 25B
decreases expression
ISO
nickel sulfate results in decreased expression of CDC25B mRNA
CTD
PMID:22714537
NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
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Cdc34
cell division cycle 34, ubiqiutin conjugating enzyme
increases expression
ISO
nickel sulfate results in increased expression of CDC34 mRNA
CTD
PMID:18651567
NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
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Cdh1
cadherin 1
decreases expression multiple interactions
ISO
nickel sulfate results in decreased expression of CDH1 mRNA; nickel sulfate results in decreased expression of CDH1 protein pyrazolanthrone promotes the reaction [nickel sulfate results in decreased expression of CDH1 protein]
CTD
PMID:15588916 PMID:16780908 PMID:22648416
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh13
cadherin 13
decreases expression
ISO
nickel sulfate results in decreased expression of CDH13 mRNA
CTD
PMID:22714537
NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
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Cdh16
cadherin 16
decreases expression
ISO
nickel sulfate results in decreased expression of CDH16 mRNA
CTD
PMID:16166746
NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007
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Cdh3
cadherin 3
decreases expression
ISO
nickel sulfate results in decreased expression of CDH3 mRNA
CTD
PMID:22714537
NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
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Cdh8
cadherin 8
decreases expression
ISO
nickel sulfate results in decreased expression of CDH8 mRNA
CTD
PMID:17374397
NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
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Cdk10
cyclin-dependent kinase 10
increases expression
ISO
nickel sulfate results in increased expression of CDK10 mRNA
CTD
PMID:22714537
NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
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Cdk14
cyclin-dependent kinase 14
decreases expression
ISO
nickel sulfate results in decreased expression of CDK14 mRNA
CTD
PMID:22714537
NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861
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Cdk6
cyclin-dependent kinase 6
decreases expression
ISO
nickel sulfate results in decreased expression of CDK6 mRNA
CTD
PMID:22714537
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdkl2
cyclin dependent kinase like 2
increases expression
ISO
nickel sulfate results in increased expression of CDKL2 mRNA
CTD
PMID:22714537
NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
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Cdkl5
cyclin-dependent kinase-like 5
decreases expression
ISO
nickel sulfate results in decreased expression of CDKL5 mRNA
CTD
PMID:22714537
NCBI chr X:33,757,605...33,988,075
Ensembl chr X:33,821,257...33,986,582
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
nickel sulfate results in increased expression of CDKN1A mRNA
CTD
PMID:16100012 PMID:16166746 PMID:16314067
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn2d
cyclin dependent kinase inhibitor 2D
increases expression
ISO
nickel sulfate results in increased expression of CDKN2D mRNA
CTD
PMID:17382205
NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
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Cdo1
cysteine dioxygenase type 1
decreases expression
ISO
nickel sulfate results in decreased expression of CDO1 mRNA
CTD
PMID:22714537
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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Cds2
CDP-diacylglycerol synthase 2
decreases expression
ISO
nickel sulfate results in decreased expression of CDS2 mRNA
CTD
PMID:22714537
NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
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Cdt1
chromatin licensing and DNA replication factor 1
increases expression
ISO
nickel sulfate results in increased expression of CDT1 mRNA
CTD
PMID:22714537
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
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Cept1
choline/ethanolamine phosphotransferase 1
decreases expression
ISO
nickel sulfate results in decreased expression of CEPT1 mRNA
CTD
PMID:16780908
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
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Cerkl
ceramide kinase-like
decreases expression
ISO
nickel sulfate results in decreased expression of CERKL mRNA
CTD
PMID:17374397
NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675
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Cers6
ceramide synthase 6
increases expression
ISO
nickel sulfate results in increased expression of LASS6 mRNA
CTD
PMID:22714537
NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
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Cfap119
cilia and flagella associated protein 119
increases expression
ISO
nickel sulfate results in increased expression of CFAP119 mRNA
CTD
PMID:22714537
NCBI chr 1:182,197,171...182,216,936
Ensembl chr 1:182,192,947...182,202,338
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Cfap251
cilia and flagella associated protein 251
decreases expression
ISO
nickel sulfate results in decreased expression of CFAP251 mRNA
CTD
PMID:22714537
NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932
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Cfap44
cilia and flagella associated protein 44
decreases expression
ISO
nickel sulfate results in decreased expression of CFAP44 mRNA
CTD
PMID:22714537
NCBI chr11:56,199,772...56,283,964
Ensembl chr11:56,201,049...56,283,986
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Cfap69
cilia and flagella associated protein 69
increases expression
ISO
nickel sulfate results in increased expression of CFAP69 mRNA
CTD
PMID:22714537
NCBI chr 4:28,379,604...28,452,562
Ensembl chr 4:28,375,996...28,450,698
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Cflar
CASP8 and FADD-like apoptosis regulator
increases expression
ISO
nickel sulfate results in increased expression of CFLAR mRNA
CTD
PMID:16780908
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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Cga
glycoprotein hormones, alpha polypeptide
increases expression multiple interactions
ISO EXP
nickel sulfate results in increased expression of CGA mRNA [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 protein; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 protein; [CGA protein co-treated with nickel sulfate] results in decreased expression of HSD17B3 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of STAR mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of STAR protein
CTD
PMID:18651567 PMID:29567110
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Chd1l
chromodomain helicase DNA binding protein 1-like
decreases expression
ISO
nickel sulfate results in decreased expression of CHD1L mRNA
CTD
PMID:22714537
NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595
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Chka
choline kinase alpha
increases expression
ISO
nickel sulfate results in increased expression of CHKA mRNA
CTD
PMID:16780908
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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Chmp1a
charged multivesicular body protein 1A
increases expression
ISO
nickel sulfate results in increased expression of CHMP1A mRNA
CTD
PMID:22714537
NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
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Chrdl1
chordin-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of CHRDL1 mRNA
CTD
PMID:22714537
NCBI chr X:106,889,125...106,992,937
Ensembl chr X:106,889,125...106,992,921
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Chst11
carbohydrate sulfotransferase 11
decreases expression
ISO
nickel sulfate results in decreased expression of CHST11 mRNA
CTD
PMID:22714537
NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
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Chst15
carbohydrate sulfotransferase 15
decreases expression
ISO
nickel sulfate results in decreased expression of CHST15 mRNA
CTD
PMID:22714537
NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707
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Cidea
cell death-inducing DFFA-like effector a
multiple interactions decreases expression
ISO
[nickel sulfate co-treated with Particulate Matter] results in decreased expression of CIDEA mRNA nickel sulfate results in decreased expression of CIDEA mRNA
CTD
PMID:23126276
NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
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Cidec
cell death-inducing DFFA-like effector c
increases expression
ISO
nickel sulfate results in increased expression of CIDEC mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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Cisd1
CDGSH iron sulfur domain 1
decreases expression
ISO
nickel sulfate results in decreased expression of CISD1 mRNA
CTD
PMID:17374397
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
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Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
decreases expression
ISO
nickel sulfate results in decreased expression of CITED2 mRNA
CTD
PMID:18651567
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
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Ckb
creatine kinase B
decreases expression
ISO
nickel sulfate results in decreased expression of CKB mRNA
CTD
PMID:22714537
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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Clcn4
chloride voltage-gated channel 4
increases expression
ISO
nickel sulfate results in increased expression of CLCN4 mRNA
CTD
PMID:22714537
NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238
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Cldn11
claudin 11
increases expression
ISO
nickel sulfate results in increased expression of CLDN11 mRNA
CTD
PMID:22714537
NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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Clic4
chloride intracellular channel 4
increases expression
ISO
nickel sulfate results in increased expression of CLIC4 mRNA
CTD
PMID:16314067
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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Clip2
CAP-GLY domain containing linker protein 2
increases expression
ISO
nickel sulfate results in increased expression of CLIP2 mRNA
CTD
PMID:22714537
NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
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Cltb
clathrin, light chain B
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of CLTB mRNA nickel sulfate results in increased expression of CLTB mRNA
CTD
PMID:16780908 PMID:18651567
NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
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Cmbl
carboxymethylenebutenolidase homolog
increases expression
ISO
nickel sulfate results in increased expression of CMBL mRNA
CTD
PMID:22714537
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
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Cmip
c-Maf-inducing protein
increases expression
ISO
nickel sulfate results in increased expression of CMIP mRNA
CTD
PMID:22714537
NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709
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Cmpk2
cytidine/uridine monophosphate kinase 2
decreases expression
ISO
nickel sulfate results in decreased expression of CMPK2 mRNA
CTD
PMID:17374397
NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
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Cnn1
calponin 1
decreases expression
ISO
nickel sulfate results in decreased expression of CNN1 mRNA
CTD
PMID:22714537
NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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Cnnm1
cyclin and CBS domain divalent metal cation transport mediator 1
decreases expression
ISO
nickel sulfate results in decreased expression of CNNM1 mRNA
CTD
PMID:22714537
NCBI chr 1:242,296,367...242,354,957
Ensembl chr 1:242,296,422...242,353,513
G
Cntnap1
contactin associated protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of CNTNAP1 mRNA
CTD
PMID:22714537
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
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Cntnap3
contactin associated protein family member 3
increases expression
ISO
nickel sulfate results in increased expression of CNTNAP3 mRNA
CTD
PMID:22714537
NCBI chr17:267,379...455,478
Ensembl chr17:267,508...454,102
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Coch
cochlin
decreases expression
ISO
nickel sulfate results in decreased expression of COCH mRNA
CTD
PMID:22714537
NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
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Col12a1
collagen type XII alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL12A1 mRNA
CTD
PMID:22714537
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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Col15a1
collagen type XV alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL15A1 mRNA
CTD
PMID:16166746
NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
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Col16a1
collagen type XVI alpha 1 chain
increases expression
ISO
nickel sulfate results in increased expression of COL16A1 mRNA
CTD
PMID:18651567
NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:142,388,426...142,442,825
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL1A1 mRNA
CTD
PMID:16166746
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col3a1
collagen type III alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL3A1 mRNA
CTD
PMID:16166746
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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Col4a1
collagen type IV alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL4A1 mRNA
CTD
PMID:22714537
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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Col4a4
collagen type IV alpha 4 chain
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of COL4A4 mRNA
CTD
PMID:31734292
NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
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Col4a5
collagen type IV alpha 5 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL4A5 mRNA
CTD
PMID:16166746
NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692
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Col5a1
collagen type V alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL5A1 mRNA
CTD
PMID:16166746
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Col5a2
collagen type V alpha 2 chain
increases expression
ISO
nickel sulfate results in increased expression of COL5A2 mRNA
CTD
PMID:22714537
NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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Col6a3
collagen type VI alpha 3 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL6A3 mRNA
CTD
PMID:16166746
NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
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Col8a1
collagen type VIII alpha 1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of COL8A1 mRNA
CTD
PMID:22714537
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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Commd3
COMM domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of COMMD3 mRNA
CTD
PMID:22714537
NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177
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Comt
catechol-O-methyltransferase
increases expression
ISO
nickel sulfate results in increased expression of COMT mRNA
CTD
PMID:18651567
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Coro2b
coronin 2B
decreases expression
ISO
nickel sulfate results in decreased expression of CORO2B mRNA
CTD
PMID:22714537
NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
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Cpe
carboxypeptidase E
decreases expression
ISO
nickel sulfate results in decreased expression of CPE mRNA
CTD
PMID:22714537
NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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Cpeb3
cytoplasmic polyadenylation element binding protein 3
decreases expression
ISO
nickel sulfate results in decreased expression of CPEB3 mRNA
CTD
PMID:22714537
NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
G
Cpne3
copine 3
decreases expression
ISO
nickel sulfate results in decreased expression of CPNE3 mRNA
CTD
PMID:17374397
NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
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Cpped1
calcineurin-like phosphoesterase domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of CPPED1 mRNA
CTD
PMID:22714537
NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054
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Cpq
carboxypeptidase Q
increases expression
ISO
nickel sulfate results in increased expression of PGCP mRNA
CTD
PMID:22714537
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
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Cpt1c
carnitine palmitoyltransferase 1c
decreases expression
ISO
nickel sulfate results in decreased expression of CPT1C mRNA
CTD
PMID:22714537
NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342
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Cpvl
carboxypeptidase, vitellogenic-like
increases expression
ISO
nickel sulfate results in increased expression of CPVL mRNA
CTD
PMID:22714537
NCBI chr 4:82,981,421...83,091,730
Ensembl chr 4:82,981,422...83,085,655
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Crabp2
cellular retinoic acid binding protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of CRABP2 mRNA
CTD
PMID:22714537
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Creb1
cAMP responsive element binding protein 1
affects expression multiple interactions increases phosphorylation
ISO
nickel sulfate affects the expression of CREB1 mRNA puerarin inhibits the reaction [nickel sulfate results in increased phosphorylation of CREB1 protein] [nickel sulfate co-treated with Dinoprostone] results in increased expression of CREB1 protein; CREB1 protein promotes the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein]
CTD
PMID:20385217 PMID:23526216 PMID:26607348
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Creb5
cAMP responsive element binding protein 5
decreases expression
ISO
nickel sulfate results in decreased expression of CREB5 mRNA
CTD
PMID:22714537
NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
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Crem
cAMP responsive element modulator
increases expression
ISO
nickel sulfate results in increased expression of CREM mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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Crim1
cysteine rich transmembrane BMP regulator 1
increases expression
ISO
nickel sulfate results in increased expression of CRIM1 mRNA
CTD
PMID:16780908
NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
G
Crls1
cardiolipin synthase 1
decreases expression
ISO
nickel sulfate results in decreased expression of CRLS1 mRNA
CTD
PMID:22714537
NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
G
Crnkl1
crooked neck pre-mRNA splicing factor 1
decreases expression
ISO
nickel sulfate results in decreased expression of CRNKL1 mRNA
CTD
PMID:22714537
NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302 Ensembl chr 6:133,337,039...133,354,302
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Crybg3
crystallin beta-gamma domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of CRYBG3 mRNA
CTD
PMID:22714537
NCBI chr11:40,749,198...40,861,753
Ensembl chr11:40,749,214...40,861,752
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Csf2rb
colony stimulating factor 2 receptor subunit beta
affects expression
ISO
nickel sulfate affects the expression of CSF2RB mRNA
CTD
PMID:18202158
NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
G
Csf3r
colony stimulating factor 3 receptor
increases expression
ISO
nickel sulfate results in increased expression of CSF3R mRNA
CTD
PMID:17382205
NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
G
Csnk2a1
casein kinase 2 alpha 1
decreases expression
ISO
nickel sulfate results in decreased expression of CSNK2A1 mRNA
CTD
PMID:22714537
NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
G
Cspg4
chondroitin sulfate proteoglycan 4
decreases expression
ISO
nickel sulfate results in decreased expression of CSPG4 mRNA
CTD
PMID:22714537
NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010
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Csta
cystatin A
decreases expression
ISO
nickel sulfate results in decreased expression of CSTA mRNA
CTD
PMID:18651567
NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
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Cth
cystathionine gamma-lyase
decreases expression
ISO
nickel sulfate results in decreased expression of CTH mRNA
CTD
PMID:22714537
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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Ctnnal1
catenin alpha-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of CTNNAL1 mRNA
CTD
PMID:22714537
NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
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Ctps1
CTP synthase 1
increases expression
ISO
nickel sulfate results in increased expression of CTPS1 mRNA
CTD
PMID:16780908
NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
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Ctsb
cathepsin B
increases expression
ISO
nickel sulfate results in increased expression of CTSB mRNA
CTD
PMID:16314067
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Ctsc
cathepsin C
decreases expression
ISO
nickel sulfate results in decreased expression of CTSC mRNA
CTD
PMID:16780908 PMID:17374397 PMID:22714537 PMID:25673294
NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
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Ctsf
cathepsin F
decreases expression
ISO
nickel sulfate results in decreased expression of CTSF mRNA
CTD
PMID:22714537
NCBI chr 1:202,152,777...202,158,525
Ensembl chr 1:202,152,728...202,158,525
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Ctsl
cathepsin L
increases expression decreases expression
ISO
nickel sulfate results in increased expression of CTSL mRNA nickel sulfate results in decreased expression of CTSL mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Cul4b
cullin 4B
decreases expression
ISO
nickel sulfate results in decreased expression of CUL4B mRNA
CTD
PMID:16100012
NCBI chr X:117,287,481...117,326,688
Ensembl chr X:117,287,484...117,326,688
G
Cxadr
CXADR, Ig-like cell adhesion molecule
decreases expression
ISO
nickel sulfate results in decreased expression of CXADR mRNA
CTD
PMID:22714537
NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
G
Cxcl1
C-X-C motif chemokine ligand 1
multiple interactions increases expression
ISO
HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]; macrophage stimulatory lipopeptide 2 promotes the reaction [nickel sulfate results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL1 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL1 protein]
CTD
PMID:16780908 PMID:18832182
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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Cxcl10
C-X-C motif chemokine ligand 10
increases expression decreases expression multiple interactions
ISO
nickel sulfate results in increased expression of CXCL10 mRNA nickel sulfate results in decreased expression of CXCL10 mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of CXCL10 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein]]; nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL10 mRNA]; nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein]
CTD
PMID:12060402 PMID:18096868 PMID:18832182 PMID:23445166
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cxcl16
C-X-C motif chemokine ligand 16
increases expression
ISO
nickel sulfate results in increased expression of CXCL16 mRNA
CTD
PMID:22714537
NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
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Cxcl2
C-X-C motif chemokine ligand 2
affects expression increases expression
ISO EXP
nickel sulfate affects the expression of CXCL2 mRNA nickel sulfate results in increased expression of CXCL2 mRNA
CTD
PMID:11708899 PMID:18202158
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions increases expression
ISO
HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]; macrophage stimulatory lipopeptide 2 promotes the reaction [nickel sulfate results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL1 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL1 protein]
CTD
PMID:16166746 PMID:16780908 PMID:18832182
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcl6
C-X-C motif chemokine ligand 6
multiple interactions
ISO
nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL6 mRNA]
CTD
PMID:18832182
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression increases expression affects expression
ISO
nickel sulfate results in decreased expression of CXCR4 protein nickel sulfate results in increased expression of CXCR4 mRNA nickel sulfate affects the expression of CXCR4 mRNA
CTD
PMID:15924226 PMID:16780908 PMID:17374397 PMID:17382205 PMID:18202158
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cxhxorf38
similar to human chromosome X open reading frame 38
decreases expression
ISO
nickel sulfate results in decreased expression of CXORF38 mRNA
CTD
PMID:22714537
NCBI chr X:10,128,070...10,150,904
Ensembl chr X:10,129,657...10,150,900
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Cyba
cytochrome b-245 alpha chain
increases expression
ISO
nickel sulfate results in increased expression of CYBA mRNA
CTD
PMID:22714537
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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Cycs
cytochrome c, somatic
increases expression multiple interactions
EXP ISO
nickel sulfate results in increased expression of CYCS mRNA; nickel sulfate results in increased expression of CYCS protein Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]
CTD
PMID:28296042 PMID:34612572
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cygb
cytoglobin
decreases expression
ISO
nickel sulfate results in decreased expression of CYGB mRNA
CTD
PMID:22714537
NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
decreases expression multiple interactions
EXP
nickel sulfate results in decreased expression of CYP11A1 mRNA; nickel sulfate results in decreased expression of CYP11A1 protein [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 protein; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]
CTD
PMID:29567110
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
multiple interactions decreases expression
EXP
[CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 protein; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] nickel sulfate results in decreased expression of CYP17A1 mRNA; nickel sulfate results in decreased expression of CYP17A1 protein
CTD
PMID:29567110
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression decreases expression
ISO
nickel sulfate results in increased expression of CYP1A1 mRNA nickel sulfate results in decreased expression of CYP1A1 mRNA
CTD
PMID:20491607 PMID:20713136
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases expression multiple interactions
ISO EXP
nickel sulfate results in decreased expression of CYP1B1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CYP1B1 mRNA
CTD
PMID:22714537 PMID:31734292
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
decreases expression multiple interactions increases expression
ISO EXP
nickel sulfate results in decreased expression of CYP27A1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CYP27A1 mRNA nickel sulfate results in increased expression of CYP27A1 mRNA
CTD
PMID:20713136 PMID:22714537 PMID:31734292
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
decreases expression
ISO
nickel sulfate results in decreased expression of CYP2B10 mRNA
CTD
PMID:16100012
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression decreases expression
ISO
nickel sulfate affects the expression of CYP2F2 mRNA nickel sulfate results in decreased expression of CYP2F2 mRNA
CTD
PMID:12718980 PMID:16100012
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
decreases expression
ISO
nickel sulfate results in decreased expression of CYP2U1 mRNA
CTD
PMID:22714537
NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
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Cytip
cytohesin 1 interacting protein
increases expression
ISO
nickel sulfate results in increased expression of CYTIP mRNA
CTD
PMID:17374397
NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
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Dab1
DAB adaptor protein 1
increases expression
ISO
nickel sulfate results in increased expression of DAB1 mRNA
CTD
PMID:16780908
NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552
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Dact1
dishevelled-binding antagonist of beta-catenin 1
decreases expression
ISO
nickel sulfate results in decreased expression of DACT1 mRNA
CTD
PMID:22714537
NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
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Dapk1
death associated protein kinase 1
decreases expression
ISO
nickel sulfate results in decreased expression of DAPK1 mRNA
CTD
PMID:22714537
NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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Dcbld2
discoidin, CUB and LCCL domain containing 2
decreases expression
ISO
nickel sulfate results in decreased expression of DCBLD2 mRNA
CTD
PMID:22714537
NCBI chr11:42,125,525...42,179,927
Ensembl chr11:42,125,787...42,179,697
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Dclk2
doublecortin-like kinase 2
increases expression
ISO
nickel sulfate results in increased expression of DCLK2 mRNA
CTD
PMID:22714537
NCBI chr 2:172,202,733...172,338,411
Ensembl chr 2:172,208,706...172,338,250
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Dct
dopachrome tautomerase
increases expression
ISO
nickel sulfate results in increased expression of DCT mRNA
CTD
PMID:16780908
NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
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Dctpp1
dCTP pyrophosphatase 1
decreases expression
ISO
nickel sulfate results in decreased expression of DCTPP1 mRNA
CTD
PMID:17374397
NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839
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Ddah2
DDAH family member 2, ADMA-independent
increases expression
ISO
nickel sulfate results in increased expression of DDAH2 mRNA
CTD
PMID:22714537
NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
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Ddit3
DNA-damage inducible transcript 3
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein] nickel sulfate results in increased expression of DDIT3 mRNA; nickel sulfate results in increased expression of DDIT3 protein
CTD
PMID:28296042
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddit4
DNA-damage-inducible transcript 4
increases expression
ISO
nickel sulfate results in increased expression of DDIT4 mRNA
CTD
PMID:18651567
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Ddo
D-aspartate oxidase
increases expression
ISO
nickel sulfate results in increased expression of DDO mRNA
CTD
PMID:22714537
NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
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Ddr1
discoidin domain receptor tyrosine kinase 1
increases expression
ISO
nickel sulfate results in increased expression of DDR1 mRNA
CTD
PMID:22714537
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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Ddr2
discoidin domain receptor tyrosine kinase 2
increases expression
ISO
nickel sulfate results in increased expression of DDR2 mRNA
CTD
PMID:22714537
NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
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Ddrgk1
DDRGK domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of DDRGK1 mRNA
CTD
PMID:22714537
NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
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Ddx17
DEAD-box helicase 17
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of DDX17 mRNA
CTD
PMID:31734292
NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
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Ddx39b
DExD-box helicase 39B
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of DDX39B mRNA
CTD
PMID:31734292
NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
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Deaf1
DEAF1 transcription factor
increases expression
ISO
nickel sulfate results in increased expression of DEAF1 mRNA
CTD
PMID:16780908
NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
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Def8
differentially expressed in FDCP 8 homolog
increases expression
ISO
nickel sulfate results in increased expression of DEF8 mRNA
CTD
PMID:22714537
NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638
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Dennd1b
DENN domain containing 1B
increases expression
ISO
nickel sulfate results in increased expression of DENND1B mRNA
CTD
PMID:22714537
NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601
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Dennd2d
DENN domain containing 2D
decreases expression
ISO
nickel sulfate results in decreased expression of DENND2D mRNA
CTD
PMID:22714537
NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270
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Depp1
DEPP autophagy regulator 1
increases expression
ISO
nickel sulfate results in increased expression of DEPP1 mRNA
CTD
PMID:16780908 PMID:17382205
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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Dgka
diacylglycerol kinase, alpha
decreases expression
ISO
nickel sulfate results in decreased expression of DGKA mRNA
CTD
PMID:22714537
NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
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Dgkh
diacylglycerol kinase, eta
decreases expression
ISO
nickel sulfate results in decreased expression of DGKH mRNA
CTD
PMID:22714537
NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706
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Dgki
diacylglycerol kinase, iota
decreases expression
ISO
nickel sulfate results in decreased expression of DGKI mRNA
CTD
PMID:22714537
NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
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Dhrs11
dehydrogenase/reductase 11
increases expression
ISO
nickel sulfate results in increased expression of DHRS11 mRNA
CTD
PMID:22714537
NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
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Diaph2
diaphanous-related formin 2
decreases expression
ISO
nickel sulfate results in decreased expression of DIAPH2 mRNA
CTD
PMID:22714537
NCBI chr X:92,395,189...93,234,521
Ensembl chr X:92,395,251...93,229,869
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Dio2
iodothyronine deiodinase 2
increases expression
ISO
nickel sulfate results in increased expression of DIO2 mRNA
CTD
PMID:22714537
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
G
Dkc1
dyskerin pseudouridine synthase 1
decreases expression
ISO
nickel sulfate results in decreased expression of DKC1 mRNA
CTD
PMID:16780908 PMID:17374397
G
Dlx1
distal-less homeobox 1
increases expression
ISO
nickel sulfate results in increased expression of DLX1 mRNA
CTD
PMID:22714537
NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780
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Dlx2
distal-less homeobox 2
increases expression
ISO
nickel sulfate results in increased expression of DLX2 mRNA
CTD
PMID:22714537
NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597
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Dnaaf9
dynein axonemal assembly factor 9
decreases expression
ISO
nickel sulfate results in decreased expression of DNAAF9 mRNA
CTD
PMID:22714537
NCBI chr 3:117,918,047...118,052,641
Ensembl chr 3:117,921,620...118,052,630
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Dnah11
dynein, axonemal, heavy chain 11
increases expression
ISO
nickel sulfate results in increased expression of DNAH11 mRNA
CTD
PMID:22714537
NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536
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Dnah9
dynein, axonemal, heavy chain 9
decreases expression
ISO
nickel sulfate results in decreased expression of DNAH9 mRNA
CTD
PMID:18651567
NCBI chr10:50,496,174...50,864,909
Ensembl chr10:50,497,688...50,864,949
G
Dnaja4
DnaJ heat shock protein family (Hsp40) member A4
decreases expression
ISO
nickel sulfate results in decreased expression of DNAJA4 mRNA
CTD
PMID:22714537
NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
G
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
increases expression
ISO
nickel sulfate results in increased expression of DNAJB6 mRNA
CTD
PMID:17374397
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
G
Dnajc1
DnaJ heat shock protein family (Hsp40) member C1
decreases expression
ISO
nickel sulfate results in decreased expression of DNAJC1 mRNA
CTD
PMID:22714537
NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
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Dnali1
dynein, axonemal, light intermediate chain 1
decreases expression
ISO
nickel sulfate results in decreased expression of DNALI1 mRNA
CTD
PMID:22714537
NCBI chr 5:137,318,475...137,327,313
Ensembl chr 5:137,318,477...137,327,336
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Dnm3
dynamin 3
decreases expression
ISO
nickel sulfate results in decreased expression of DNM3 mRNA
CTD
PMID:22714537
NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108
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Dock10
dedicator of cytokinesis 10
increases expression
ISO
nickel sulfate results in increased expression of DOCK10 mRNA
CTD
PMID:22714537
NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
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Dock11
dedicator of cytokinesis 11
increases expression
ISO
nickel sulfate results in increased expression of DOCK11 mRNA
CTD
PMID:22714537
NCBI chr X:115,131,720...115,314,854
Ensembl chr X:115,131,909...115,314,854
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Dpp4
dipeptidylpeptidase 4
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of DPP4 mRNA nickel sulfate results in increased expression of DPP4 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp7
dipeptidylpeptidase 7
decreases expression
ISO
nickel sulfate results in decreased expression of DPP7 mRNA
CTD
PMID:22714537
NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
G
Dpy19l3
dpy-19 like C-mannosyltransferase 3
decreases expression
ISO
nickel sulfate results in decreased expression of DPY19L3 mRNA
CTD
PMID:22714537
NCBI chr 1:88,350,303...88,417,339
Ensembl chr 1:88,350,303...88,417,339
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Dpyd
dihydropyrimidine dehydrogenase
decreases expression
ISO
nickel sulfate results in decreased expression of DPYD mRNA
CTD
PMID:17374397
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
G
Dram1
DNA-damage regulated autophagy modulator 1
increases expression
ISO
nickel sulfate results in increased expression of DRAM1 mRNA
CTD
PMID:22714537
NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
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Dse
dermatan sulfate epimerase
decreases expression
ISO
nickel sulfate results in decreased expression of DSE mRNA
CTD
PMID:17374397
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
G
Dsel
dermatan sulfate epimerase-like
increases expression
ISO
nickel sulfate results in increased expression of DSEL mRNA
CTD
PMID:22714537
NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
G
Dsg2
desmoglein 2
increases expression
ISO
nickel sulfate results in increased expression of DSG2 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
G
Dstn
destrin, actin depolymerizing factor
decreases expression
ISO
nickel sulfate results in decreased expression of DSTN mRNA
CTD
PMID:22714537
NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
G
Dtd1
D-aminoacyl-tRNA deacylase 1
decreases expression
ISO
nickel sulfate results in decreased expression of DTD1 mRNA
CTD
PMID:22714537
NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659
G
Dtx3
deltex E3 ubiquitin ligase 3
decreases expression
ISO
nickel sulfate results in decreased expression of DTX3 mRNA
CTD
PMID:22714537
NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
G
Dusp1
dual specificity phosphatase 1
increases expression
ISO
nickel sulfate results in increased expression of DUSP1 mRNA
CTD
PMID:16314067
NCBI chr10:16,680,478...16,683,275
G
Dusp10
dual specificity phosphatase 10
increases expression
ISO
nickel sulfate results in increased expression of DUSP10 mRNA
CTD
PMID:22714537
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
G
Dusp22
dual specificity phosphatase 22
increases expression
ISO
nickel sulfate results in increased expression of DUSP22 mRNA
CTD
PMID:22714537
NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
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Dusp23
dual specificity phosphatase 23
decreases expression
ISO
nickel sulfate results in decreased expression of DUSP23 mRNA
CTD
PMID:22714537
NCBI chr13:85,097,899...85,100,054
Ensembl chr13:85,097,899...85,100,093
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Dusp4
dual specificity phosphatase 4
increases expression
ISO
nickel sulfate results in increased expression of DUSP4 mRNA
CTD
PMID:16780908
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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Dusp5
dual specificity phosphatase 5
increases expression
ISO
nickel sulfate results in increased expression of DUSP5 mRNA
CTD
PMID:16780908
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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Dync2h1
dynein cytoplasmic 2 heavy chain 1
decreases expression
ISO
nickel sulfate results in decreased expression of DYNC2H1 mRNA
CTD
PMID:22714537
NCBI chr 8:4,189,067...4,412,183
Ensembl chr 8:4,189,257...4,412,183
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Dysf
dysferlin
decreases expression
ISO
nickel sulfate results in decreased expression of DYSF mRNA
CTD
PMID:22714537
NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709
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Ebi3
Epstein-Barr virus induced 3
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of EBI3 mRNA BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of EBI3 mRNA]; TLR4 protein affects the reaction [nickel sulfate results in increased expression of EBI3 mRNA]
CTD
PMID:16780908 PMID:30421605
NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
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Ece1
endothelin converting enzyme 1
increases expression
ISO
nickel sulfate results in increased expression of ECE1 mRNA
CTD
PMID:16780908
NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
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Echdc3
enoyl CoA hydratase domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of ECHDC3 mRNA
CTD
PMID:22714537
NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
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Ecm1
extracellular matrix protein 1
increases expression
ISO
nickel sulfate results in increased expression of ECM1 mRNA
CTD
PMID:18651567
NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
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Edaradd
EDAR associated via death domain
increases expression
ISO
nickel sulfate results in increased expression of EDARADD mRNA
CTD
PMID:22714537
NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447
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Edem3
ER degradation enhancing alpha-mannosidase like protein 3
decreases expression
ISO
nickel sulfate results in decreased expression of EDEM3 mRNA
CTD
PMID:22714537
NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
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Edil3
EGF like repeats and discoidin domains 3
decreases expression
ISO
nickel sulfate results in decreased expression of EDIL3 mRNA
CTD
PMID:22714537
NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008
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Edn1
endothelin 1
increases expression
ISO
nickel sulfate results in increased expression of EDN1 mRNA
CTD
PMID:22714537
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Efemp2
EGF containing fibulin extracellular matrix protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of EFEMP2 mRNA
CTD
PMID:22714537
NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414
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Efhc1
EF-hand domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of EFHC1 mRNA
CTD
PMID:22714537
NCBI chr 9:23,375,815...23,414,283
Ensembl chr 9:23,375,840...23,414,283
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Efna1
ephrin A1
multiple interactions increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of EFNA1 mRNA nickel sulfate results in increased expression of EFNA1 mRNA
CTD
PMID:18651567 PMID:18832182
NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
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Efna3
ephrin A3
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of EFNA3 mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of EFNA3 mRNA
CTD
PMID:18832182
NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
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Efna5
ephrin A5
decreases expression
ISO
nickel sulfate results in decreased expression of EFNA5 mRNA
CTD
PMID:22714537
NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
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Egfr
epidermal growth factor receptor
multiple interactions
ISO
[TGFA protein binds to and affects the activity of EGFR protein] which results in decreased susceptibility to nickel sulfate
CTD
PMID:19131640
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Egr1
early growth response 1
increases expression
ISO
nickel sulfate results in increased expression of EGR1 mRNA
CTD
PMID:16780908
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
increases expression
ISO
nickel sulfate results in increased expression of EHHADH mRNA
CTD
PMID:17374397 PMID:22714537
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Ehmt2
euchromatic histone lysine methyltransferase 2
increases expression
ISO
nickel sulfate results in increased expression of EHMT2 mRNA
CTD
PMID:22714537
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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Ei24
EI24, autophagy associated transmembrane protein
decreases expression
ISO
nickel sulfate results in decreased expression of EI24 mRNA
CTD
PMID:18651567
NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
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Eif1ax
eukaryotic translation initiation factor 1A, X-linked
decreases expression
ISO
nickel sulfate results in decreased expression of EIF1A mRNA
CTD
PMID:18651567
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
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Eif4g1
eukaryotic translation initiation factor 4 gamma 1
increases expression
ISO
nickel sulfate results in increased expression of EIF4G1 mRNA
CTD
PMID:18651567
NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
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Eln
elastin
increases expression
ISO
nickel sulfate results in increased expression of ELN mRNA
CTD
PMID:16100012
NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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Elovl2
ELOVL fatty acid elongase 2
increases expression
ISO
nickel sulfate results in increased expression of ELOVL2 mRNA
CTD
PMID:22714537
NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848
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Elovl3
ELOVL fatty acid elongase 3
multiple interactions
ISO
[nickel sulfate co-treated with Particulate Matter] results in decreased expression of ELOVL3 mRNA
CTD
PMID:23126276
NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
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Elovl7
ELOVL fatty acid elongase 7
increases expression
ISO
nickel sulfate results in increased expression of ELOVL7 mRNA
CTD
PMID:22714537
NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845
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Emb
embigin
decreases expression
ISO
nickel sulfate results in decreased expression of EMB mRNA
CTD
PMID:17374397
NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050
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Emc8
ER membrane protein complex subunit 8
increases expression
ISO
nickel sulfate results in increased expression of EMC8 mRNA
CTD
PMID:22714537
NCBI chr19:48,708,304...48,721,626
Ensembl chr19:48,582,574...48,721,543
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Eml1
EMAP like 1
increases expression
ISO
nickel sulfate results in increased expression of EML1 mRNA
CTD
PMID:22714537
NCBI chr 6:127,283,968...127,457,246
Ensembl chr 6:127,284,029...127,457,246
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Emp1
epithelial membrane protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of EMP1 mRNA
CTD
PMID:22714537
NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
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Enc1
ectodermal-neural cortex 1
decreases expression
ISO
nickel sulfate results in decreased expression of ENC1 mRNA
CTD
PMID:16780908
NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
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Endod1
endonuclease domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of ENDOD1 mRNA
CTD
PMID:22714537
NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892
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Eno1
enolase 1
increases expression
ISO
nickel sulfate results in increased expression of ENO1 mRNA
CTD
PMID:16100012
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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Eno2
enolase 2
increases expression
ISO
nickel sulfate results in increased expression of ENO2 mRNA
CTD
PMID:17382205
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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Eno3
enolase 3
affects expression
ISO
nickel sulfate affects the expression of ENO3 mRNA
CTD
PMID:12718980
NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
increases expression
ISO
nickel sulfate results in increased expression of ENPP1 mRNA
CTD
PMID:22714537
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
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Enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
decreases expression
ISO
nickel sulfate results in decreased expression of ENPP4 mRNA
CTD
PMID:22714537
NCBI chr 9:16,888,923...16,898,860
Ensembl chr 9:16,887,739...16,898,860
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Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
increases expression
ISO
nickel sulfate results in increased expression of ENTPD1 mRNA
CTD
PMID:16780908
NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
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Entpd6
ectonucleoside triphosphate diphosphohydrolase 6
decreases expression
ISO
nickel sulfate results in decreased expression of ENTPD6 mRNA
CTD
PMID:22714537
NCBI chr 3:139,575,659...139,598,163
Ensembl chr 3:139,575,686...139,598,154
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Epas1
endothelial PAS domain protein 1
multiple interactions increases expression increases stability
ISO
[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein]; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] nickel sulfate results in increased expression of EPAS1 mRNA; nickel sulfate results in increased expression of EPAS1 protein nickel sulfate results in increased stability of EPAS1 protein
CTD
PMID:16288478 PMID:20046830 PMID:22714537
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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Epcam
epithelial cell adhesion molecule
decreases expression
ISO
nickel sulfate results in decreased expression of EPCAM mRNA
CTD
PMID:22714537
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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Epdr1
ependymin related 1
increases expression
ISO
nickel sulfate results in increased expression of EPDR1 mRNA
CTD
PMID:22714537
NCBI chr17:45,333,932...45,358,597
Ensembl chr17:45,333,956...45,358,594
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Epha4
Eph receptor A4
increases expression
ISO
nickel sulfate results in increased expression of EPHA4 mRNA
CTD
PMID:22714537
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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Ephb6
Eph receptor B6
increases expression
ISO
nickel sulfate results in increased expression of EPHB6 mRNA
CTD
PMID:18651567
NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230
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Epm2aip1
EPM2A interacting protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of EPM2AIP1 mRNA
CTD
PMID:22714537
NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871
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Erbb3
erb-b2 receptor tyrosine kinase 3
decreases expression
ISO
nickel sulfate results in decreased expression of ERBB3 mRNA
CTD
PMID:18651567
NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
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Esd
esterase D
increases expression
ISO
nickel sulfate results in increased expression of ESD mRNA
CTD
PMID:16100012
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
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Esf1
ESF1 nucleolar pre-rRNA processing protein homolog
decreases expression
ISO
nickel sulfate results in decreased expression of ESF1 mRNA
CTD
PMID:22714537
NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
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Etl4
enhancer trap locus 4
decreases expression
ISO
nickel sulfate results in decreased expression of KIAA1217 mRNA
CTD
PMID:22714537
NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715
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Ets1
ETS proto-oncogene 1, transcription factor
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of ETS1 mRNA
CTD
PMID:31734292
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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Ets2
ETS proto-oncogene 2, transcription factor
increases expression
ISO
nickel sulfate results in increased expression of ETS2 mRNA
CTD
PMID:16780908 PMID:18651567
NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
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Etv2
ETS variant transcription factor 2
increases expression
ISO
nickel sulfate results in increased expression of ETV2 mRNA
CTD
PMID:17382205
NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
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Etv6
ETS variant transcription factor 6
increases expression
ISO
nickel sulfate results in increased expression of ETV6 mRNA
CTD
PMID:22714537
NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
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Eva1c
eva-1 homolog C
increases expression
ISO
nickel sulfate results in increased expression of EVA1C mRNA
CTD
PMID:22714537
NCBI chr11:30,089,510...30,163,596
Ensembl chr11:30,089,365...30,163,596
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Evi2b
ecotropic viral integration site 2B
increases expression
ISO
nickel sulfate results in increased expression of EVI2B mRNA
CTD
PMID:22714537
NCBI chr10:64,472,693...64,474,311
Ensembl chr10:64,471,505...64,481,560
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Exoc2
exocyst complex component 2
increases expression
ISO
nickel sulfate results in increased expression of EXOC2 mRNA
CTD
PMID:22714537
NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289
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Exoc6
exocyst complex component 6
decreases expression
ISO
nickel sulfate results in decreased expression of EXOC6 mRNA
CTD
PMID:16780908
NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015
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Exosc8
exosome component 8
decreases expression
ISO
nickel sulfate results in decreased expression of EXOSC8 mRNA
CTD
PMID:22714537
NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
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Exph5
exophilin 5
decreases expression
ISO
nickel sulfate results in decreased expression of EXPH5 mRNA
CTD
PMID:22714537
NCBI chr 8:53,698,825...53,775,371
Ensembl chr 8:53,698,852...53,773,169
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Eya1
EYA transcriptional coactivator and phosphatase 1
decreases expression
ISO
nickel sulfate results in decreased expression of EYA1 mRNA
CTD
PMID:22714537
NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
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Eya2
EYA transcriptional coactivator and phosphatase 2
decreases expression
ISO
nickel sulfate results in decreased expression of EYA2 mRNA
CTD
PMID:22714537
NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
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F13a1
coagulation factor XIII A1 chain
decreases expression
ISO
nickel sulfate results in decreased expression of F13A1 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
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F2rl2
coagulation factor II (thrombin) receptor-like 2
decreases expression
ISO
nickel sulfate results in decreased expression of F2RL2 mRNA
CTD
PMID:22714537
NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098
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F3
coagulation factor III, tissue factor
increases expression decreases expression
ISO
nickel sulfate results in increased expression of F3 mRNA nickel sulfate results in decreased expression of F3 mRNA
CTD
PMID:16100012 PMID:22714537
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Fabp3
fatty acid binding protein 3
increases expression decreases expression
ISO
nickel sulfate results in increased expression of FABP3 mRNA nickel sulfate results in decreased expression of FABP3 mRNA
CTD
PMID:17382205 PMID:22714537
NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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Fabp5
fatty acid binding protein 5
increases expression decreases expression
ISO
nickel sulfate results in increased expression of FABP5 mRNA nickel sulfate results in decreased expression of FABP5 mRNA
CTD
PMID:16780908 PMID:18651567
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
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Fam117b
family with sequence similarity 117, member B
increases expression
ISO
nickel sulfate results in increased expression of FAM117B mRNA
CTD
PMID:22714537
NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483
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Fam120c
family with sequence similarity 120 member C
increases expression
ISO
nickel sulfate results in increased expression of FAM120C mRNA
CTD
PMID:22714537
NCBI chr X:20,324,046...20,477,831
Ensembl chr X:20,323,381...20,477,275
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Fam162a
family with sequence similarity 162, member A
increases expression decreases expression
ISO
nickel sulfate results in increased expression of FAM162A mRNA nickel sulfate results in decreased expression of FAM162A mRNA
CTD
PMID:17382205 PMID:22714537
NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239
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Fam171b
family with sequence similarity 171, member B
increases expression
ISO
nickel sulfate results in increased expression of FAM171B mRNA
CTD
PMID:22714537
NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
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Fam221a
family with sequence similarity 221, member A
decreases expression
ISO
nickel sulfate results in decreased expression of FAM221A mRNA
CTD
PMID:22714537
NCBI chr 4:78,337,296...78,358,918
Ensembl chr 4:78,337,296...78,358,909
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Fam3c
FAM3 metabolism regulating signaling molecule C
decreases expression
ISO
nickel sulfate results in decreased expression of FAM3C mRNA
CTD
PMID:22714537
NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
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Fam43a
family with sequence similarity 43, member A
increases expression
ISO
nickel sulfate results in increased expression of FAM43A mRNA
CTD
PMID:22714537
NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
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Fam81a
family with sequence similarity 81, member A
increases expression
ISO
nickel sulfate results in increased expression of FAM81A mRNA
CTD
PMID:22714537
NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875
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Fanca
FA complementation group A
increases expression
ISO
nickel sulfate results in increased expression of FANCA mRNA
CTD
PMID:22714537
NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527
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Farp1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
increases expression
ISO
nickel sulfate results in increased expression of FARP1 mRNA
CTD
PMID:16780908
NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
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Fars2
phenylalanyl-tRNA synthetase 2, mitochondrial
increases expression
ISO
nickel sulfate results in increased expression of FARS2 mRNA
CTD
PMID:22714537
NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337
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Fasn
fatty acid synthase
increases expression decreases expression
ISO
nickel sulfate results in increased expression of FASN mRNA nickel sulfate results in decreased expression of FASN mRNA
CTD
PMID:16100012 PMID:16780908
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Faxc
failed axon connections homolog, metaxin like GST domain containing
increases expression
ISO
nickel sulfate results in increased expression of FAXC mRNA
CTD
PMID:22714537
NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446
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Fbln2
fibulin 2
decreases expression
ISO
nickel sulfate results in decreased expression of FBLN2 mRNA
CTD
PMID:22714537
NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
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Fbn1
fibrillin 1
decreases expression
ISO
nickel sulfate results in decreased expression of FBN1 mRNA
CTD
PMID:22714537
NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
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Fbn2
fibrillin 2
decreases expression
ISO
nickel sulfate results in decreased expression of FBN2 mRNA
CTD
PMID:22714537
NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976
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Fbxo32
F-box protein 32
increases expression
ISO
nickel sulfate results in increased expression of FBXO32 mRNA
CTD
PMID:22714537
NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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Fbxo4
F-box protein 4
decreases expression
ISO
nickel sulfate results in decreased expression of FBXO4 mRNA
CTD
PMID:22714537
NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792
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Fbxo9
f-box protein 9
decreases expression
ISO
nickel sulfate results in decreased expression of FBXO9 mRNA
CTD
PMID:18651567
NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
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Fbxw7
F-box and WD repeat domain containing 7
multiple interactions
ISO
FBXW7 mRNA affects the reaction [nickel sulfate results in increased degradation of MYC protein]; FBXW7 protein affects the reaction [nickel sulfate results in increased degradation of MYC protein]
CTD
PMID:20046830
NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
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Fcgr2b
Fc gamma receptor 2B
increases expression
ISO
nickel sulfate results in increased expression of FCGR2B mRNA
CTD
PMID:17374397
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
G
Fech
ferrochelatase
increases expression
ISO
nickel sulfate results in increased expression of FECH mRNA
CTD
PMID:20566472
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
G
Fetub
fetuin B
decreases expression
ISO
nickel sulfate results in decreased expression of FETUB mRNA
CTD
PMID:18651567
NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135
G
Fez2
fasciculation and elongation protein zeta 2
increases expression
ISO
nickel sulfate results in increased expression of FEZ2 mRNA
CTD
PMID:22714537
NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626
G
Fgf1
fibroblast growth factor 1
decreases expression
ISO
nickel sulfate results in decreased expression of FGF1 mRNA
CTD
PMID:22714537
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fgf2
fibroblast growth factor 2
increases expression
ISO
nickel sulfate results in increased expression of FGF2 mRNA
CTD
PMID:22714537
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
G
Fgf5
fibroblast growth factor 5
decreases expression
ISO
nickel sulfate results in decreased expression of FGF5 mRNA
CTD
PMID:22714537
NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997
G
Fgfr2
fibroblast growth factor receptor 2
increases expression
ISO
nickel sulfate results in increased expression of FGFR2 protein
CTD
PMID:12930308
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
G
Fgl2
fibrinogen-like 2
decreases expression
ISO
nickel sulfate results in decreased expression of FGL2 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
G
Filip1l
filamin A interacting protein 1-like
decreases expression
ISO
nickel sulfate results in decreased expression of FILIP1L mRNA
CTD
PMID:22714537
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
G
Fkbp1a
FKBP prolyl isomerase 1A
decreases expression
ISO
nickel sulfate results in decreased expression of FKBP1A mRNA
CTD
PMID:22714537
NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
G
Fkbp1b
FKBP prolyl isomerase 1B
decreases expression
ISO
nickel sulfate results in decreased expression of FKBP1B mRNA
CTD
PMID:16780908
NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
G
Flg
filaggrin
decreases expression
ISO
nickel sulfate results in decreased expression of FLG mRNA
CTD
PMID:22714537
NCBI chr 2:178,884,793...178,912,986
G
Fli1
Fli-1 proto-oncogene, ETS transcription factor
increases expression
ISO
nickel sulfate results in increased expression of FLI1 mRNA
CTD
PMID:22714537
NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433
G
Flna
filamin A
increases expression
ISO
nickel sulfate results in increased expression of FLNA mRNA
CTD
PMID:18651567
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
G
Flnc
filamin C
decreases expression
ISO
nickel sulfate results in decreased expression of FLNC mRNA
CTD
PMID:22714537
NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
G
Flot1
flotillin 1
increases expression
ISO
nickel sulfate results in increased expression of FLOT1 mRNA
CTD
PMID:22714537
NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
G
Flt1
Fms related receptor tyrosine kinase 1
increases expression
ISO
nickel sulfate results in increased expression of FLT1 mRNA
CTD
PMID:22714537
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
G
Flt3lg
Fms related receptor tyrosine kinase 3 ligand
decreases expression
ISO
nickel sulfate results in decreased expression of FLT3L mRNA
CTD
PMID:16100012
NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
G
Fmr1
fragile X messenger ribonucleoprotein 1
decreases expression
ISO
nickel sulfate results in decreased expression of FMR1 mRNA
CTD
PMID:22714537
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
G
Fn1
fibronectin 1
increases expression
ISO
nickel sulfate results in increased expression of FN1 mRNA; nickel sulfate results in increased expression of FN1 protein
CTD
PMID:22648416
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fndc3a
fibronectin type III domain containing 3a
increases expression
EXP
nickel sulfate results in increased expression of FNDC3A mRNA
CTD
PMID:11114790
NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
nickel sulfate results in increased expression of FOS mRNA
CTD
PMID:16780908 PMID:19131640
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fosl2
FOS like 2, AP-1 transcription factor subunit
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of FOSL2 mRNA nickel sulfate results in increased expression of FOSL2 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
G
Foxc2
forkhead box C2
increases expression
ISO
nickel sulfate results in increased expression of FOXC2 mRNA
CTD
PMID:16100012
NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
G
Foxf2
forkhead box F2
increases expression
ISO
nickel sulfate results in increased expression of FOXF2 mRNA
CTD
PMID:22714537
NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176
G
Fpr3
formyl peptide receptor 3
increases expression
ISO
nickel sulfate results in increased expression of FPR3 mRNA
CTD
PMID:22714537
NCBI chr 1:58,884,427...58,893,472
Ensembl chr 1:58,845,118...58,893,467
G
Frmd3
FERM domain containing 3
increases expression
ISO
nickel sulfate results in increased expression of FRMD3 mRNA
CTD
PMID:22714537
NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
G
Frmd4a
FERM domain containing 4A
decreases expression
ISO
nickel sulfate results in decreased expression of FRMD4A mRNA
CTD
PMID:22714537
NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687
G
Frmd5
FERM domain containing 5
decreases expression
ISO
nickel sulfate results in decreased expression of FRMD5 mRNA
CTD
PMID:22714537
NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498
G
Fry
FRY microtubule binding protein
decreases expression
ISO
nickel sulfate results in decreased expression of FRY mRNA
CTD
PMID:22714537
NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
G
Fst
follistatin
increases expression
ISO
nickel sulfate results in increased expression of FST mRNA
CTD
PMID:16100012
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
G
Fstl3
follistatin like 3
decreases expression
ISO
nickel sulfate results in decreased expression of FSTL3 mRNA
CTD
PMID:22714537
NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
G
Fth1
ferritin heavy chain 1
increases expression
ISO
nickel sulfate results in increased expression of FTH1 mRNA
CTD
PMID:16314067
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Ftl1
ferritin light chain 1
increases expression
ISO
nickel sulfate results in increased expression of FTL mRNA
CTD
PMID:20566472
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Ftmt
ferritin mitochondrial
increases expression
EXP
nickel sulfate results in increased expression of FTMT protein
CTD
PMID:19679144
NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
G
Fuca1
alpha-L-fucosidase 1
decreases expression
ISO
nickel sulfate results in decreased expression of FUCA1 mRNA
CTD
PMID:16780908
NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
G
Fundc2
FUN14 domain containing 2
decreases expression
ISO
nickel sulfate results in decreased expression of FUNDC2 mRNA
CTD
PMID:22714537
NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
G
Fus
Fus RNA binding protein
increases expression
ISO
nickel sulfate results in increased expression of FUS mRNA
CTD
PMID:18651567
NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
G
Fyn
FYN proto-oncogene, Src family tyrosine kinase
increases expression
ISO
nickel sulfate results in increased expression of FYN mRNA
CTD
PMID:16780908
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
G
Fzd2
frizzled class receptor 2
decreases expression
ISO
nickel sulfate results in decreased expression of FZD2 mRNA
CTD
PMID:16100012 PMID:16166746
NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
G
Fzd3
frizzled class receptor 3
decreases expression
ISO
nickel sulfate results in decreased expression of FZD3 mRNA
CTD
PMID:22714537
NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
G
Fzd6
frizzled class receptor 6
increases expression
ISO
nickel sulfate results in increased expression of FZD6 mRNA
CTD
PMID:22714537
NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
G
G4
G4 protein
increases expression
ISO
nickel sulfate results in increased expression of C6ORF47 mRNA
CTD
PMID:22714537
NCBI chr20:3,693,691...3,696,194
Ensembl chr20:3,693,649...3,696,088
G
G6pd
glucose-6-phosphate dehydrogenase
increases expression multiple interactions decreases activity
ISO EXP
nickel sulfate results in increased expression of G6PD mRNA naringin inhibits the reaction [nickel sulfate results in decreased activity of G6PD protein]
CTD
PMID:20566472 PMID:20950607
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gabarapl1
GABA type A receptor associated protein like 1
increases expression
ISO
nickel sulfate results in increased expression of GABARAPL1 mRNA
CTD
PMID:22714537
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
G
Gad1
glutamate decarboxylase 1
increases expression
ISO
nickel sulfate results in increased expression of GAD1 mRNA
CTD
PMID:22714537
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
G
Gal
galanin and GMAP prepropeptide
decreases expression
ISO
nickel sulfate results in decreased expression of GAL mRNA
CTD
PMID:22714537
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
G
Gal3st4
galactose-3-O-sulfotransferase 4
increases expression
ISO
nickel sulfate results in increased expression of GAL3ST4 mRNA
CTD
PMID:17382205
NCBI chr12:17,267,963...17,276,951
Ensembl chr12:17,267,963...17,276,833
G
Galc
galactosylceramidase
decreases expression
ISO
nickel sulfate results in decreased expression of GALC mRNA
CTD
PMID:22714537
NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830
G
Galns
galactosamine (N-acetyl)-6-sulfatase
increases expression
ISO
nickel sulfate results in increased expression of GALNS mRNA
CTD
PMID:22714537
NCBI chr19:50,628,639...50,662,477
Ensembl chr19:50,628,552...50,662,246
G
Gan
gigaxonin
increases expression
ISO
nickel sulfate results in increased expression of GAN mRNA
CTD
PMID:22714537
NCBI chr19:45,207,783...45,265,066
Ensembl chr19:45,207,184...45,254,107
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
ISO
nickel sulfate affects the expression of GAPDH mRNA
CTD
PMID:12718980
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gas6
growth arrest specific 6
decreases expression
ISO
nickel sulfate results in decreased expression of GAS6 mRNA
CTD
PMID:22714537
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
G
Gas8
growth arrest specific 8
increases expression
ISO
nickel sulfate results in increased expression of GAS8 mRNA
CTD
PMID:22714537
NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305
G
Gatm
glycine amidinotransferase
decreases expression
ISO
nickel sulfate results in decreased expression of GATM mRNA
CTD
PMID:16780908
NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
G
Gbp1
guanylate binding protein 1
increases expression
ISO
nickel sulfate results in increased expression of GBP1 mRNA
CTD
PMID:16166746
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
G
Gbp4
guanylate binding protein 4
increases expression
ISO
nickel sulfate results in increased expression of GBP4 mRNA
CTD
PMID:22714537
NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
nickel sulfate results in increased expression of GCLC mRNA
CTD
PMID:16100012 PMID:20491607 PMID:20566472
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
nickel sulfate results in increased expression of GCLM mRNA
CTD
PMID:16314067 PMID:20566472
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gcnt2
glucosaminyl (N-acetyl) transferase 2
increases expression
ISO
nickel sulfate results in increased expression of GCNT2 mRNA
CTD
PMID:22714537
NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
G
Gcnt4
glucosaminyl (N-acetyl) transferase 4
increases expression
ISO
nickel sulfate results in increased expression of GCNT4 mRNA
CTD
PMID:22714537
NCBI chr 2:28,253,325...28,283,082
Ensembl chr 2:28,252,860...28,283,082
G
Gcsh
glycine cleavage system protein H
increases expression
ISO
nickel sulfate results in increased expression of GCSH mRNA
CTD
PMID:22714537
NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792
G
Gdf15
growth differentiation factor 15
increases expression
ISO
nickel sulfate results in increased expression of GDF15 mRNA
CTD
PMID:18651567
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gdnf
glial cell derived neurotrophic factor
decreases expression
ISO
nickel sulfate results in decreased expression of GDNF mRNA
CTD
PMID:22714537
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
G
Gfpt2
glutamine-fructose-6-phosphate transaminase 2
increases expression
ISO
nickel sulfate results in increased expression of GFPT2 mRNA
CTD
PMID:22714537
NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
G
Gfra2
GDNF family receptor alpha 2
decreases expression
ISO
nickel sulfate results in decreased expression of GFRA2 mRNA
CTD
PMID:16780908
NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
G
Gfus
GDP-L-fucose synthase
increases expression
ISO
nickel sulfate results in increased expression of GFUS mRNA
CTD
PMID:18651567
NCBI chr 7:107,612,087...107,617,005
Ensembl chr 7:107,612,094...107,616,948
G
Ggt1
gamma-glutamyltransferase 1
increases activity multiple interactions
EXP
nickel sulfate results in increased activity of GGT1 protein troxerutin inhibits the reaction [nickel sulfate results in increased activity of GGT1 protein]
CTD
PMID:24112957
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
G
Gins1
GINS complex subunit 1
decreases expression
ISO
nickel sulfate results in decreased expression of GINS1 mRNA
CTD
PMID:22714537
NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
G
Gins2
GINS complex subunit 2
increases expression
ISO
nickel sulfate results in increased expression of GINS2 mRNA
CTD
PMID:22714537
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
G
Gja1
gap junction protein, alpha 1
increases expression
ISO
nickel sulfate results in increased expression of GJA1 mRNA
CTD
PMID:22714537
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Glcci1
glucocorticoid induced 1
decreases expression
ISO
nickel sulfate results in decreased expression of GLCCI1 mRNA
CTD
PMID:22714537
NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612
G
Glipr1
GLI pathogenesis-related 1
decreases expression
ISO
nickel sulfate results in decreased expression of GLIPR1 mRNA
CTD
PMID:22714537
NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
G
Glipr2
GLI pathogenesis-related 2
decreases expression
ISO
nickel sulfate results in decreased expression of GLIPR2 mRNA
CTD
PMID:22714537
NCBI chr 5:58,170,417...58,202,258
Ensembl chr 5:58,170,425...58,202,272
G
Glis3
GLIS family zinc finger 3
decreases expression
ISO
nickel sulfate results in decreased expression of GLIS3 mRNA
CTD
PMID:22714537
NCBI chr 1:225,976,029...226,395,849
Ensembl chr 1:225,976,326...226,395,899
G
Glp2r
glucagon-like peptide 2 receptor
increases expression
ISO
nickel sulfate results in increased expression of GLP2R mRNA
CTD
PMID:22714537
NCBI chr10:52,402,748...52,466,012
Ensembl chr10:52,402,748...52,466,012
G
Glrb
glycine receptor, beta
decreases expression
ISO
nickel sulfate results in decreased expression of GLRB mRNA
CTD
PMID:22714537
NCBI chr 2:166,134,616...166,207,498
Ensembl chr 2:166,134,626...166,207,489
G
Glul
glutamate-ammonia ligase
increases expression
ISO
nickel sulfate results in increased expression of GLUL mRNA
CTD
PMID:22714537
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gm2a
ganglioside GM2 activator
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of GM2A mRNA nickel sulfate results in increased expression of GM2A mRNA
CTD
PMID:16780908
NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
G
Gmpr
guanosine monophosphate reductase
increases expression
ISO
nickel sulfate results in increased expression of GMPR mRNA
CTD
PMID:22714537
NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621
G
Gna15
G protein subunit alpha 15
increases expression
ISO
nickel sulfate results in increased expression of GNA15 mRNA
CTD
PMID:22714537
NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
G
Gnal
G protein subunit alpha L
increases expression
ISO
nickel sulfate results in increased expression of GNAL mRNA
CTD
PMID:22714537
NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
G
Gnaz
G protein subunit alpha z
increases expression
ISO
nickel sulfate results in increased expression of GNAZ mRNA
CTD
PMID:22714537
NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
G
Gnb2
G protein subunit beta 2
increases expression
ISO
nickel sulfate results in increased expression of GNB2 mRNA
CTD
PMID:18651567
NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
G
Gng11
G protein subunit gamma 11
increases expression
ISO
nickel sulfate results in increased expression of GNG11 mRNA
CTD
PMID:22714537
NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442
G
Gp9
glycoprotein IX (platelet)
increases expression
ISO
nickel sulfate results in increased expression of GP9 mRNA
CTD
PMID:16780908
NCBI chr 4:120,235,500...120,237,110
Ensembl chr 4:120,235,421...120,237,110
G
Gpat3
glycerol-3-phosphate acyltransferase 3
increases expression
ISO
nickel sulfate results in increased expression of GPAT3 mRNA
CTD
PMID:22714537
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
G
Gpatch2l
G patch domain containing 2-like
decreases expression
ISO
nickel sulfate results in decreased expression of GPATCH2L mRNA
CTD
PMID:16780908
NCBI chr 6:105,883,383...105,935,644
Ensembl chr 6:105,883,460...105,934,888
G
Gpc4
glypican 4
increases expression
ISO
nickel sulfate results in increased expression of GPC4 mRNA
CTD
PMID:22714537
NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284
G
Gper1
G protein-coupled estrogen receptor 1
increases expression
ISO
nickel sulfate results in increased expression of GPER1 mRNA
CTD
PMID:22714537
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
G
Gphn
gephyrin
decreases expression
ISO
nickel sulfate results in decreased expression of GPHN mRNA
CTD
PMID:22714537
NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
G
Gpm6b
glycoprotein m6b
increases expression
ISO
nickel sulfate results in increased expression of GPM6B mRNA
CTD
PMID:17382205
NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211
G
Gpnmb
glycoprotein nmb
increases expression
ISO
nickel sulfate results in increased expression of GPNMB mRNA
CTD
PMID:16314067 PMID:22714537
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
G
Gpr39
G protein-coupled receptor 39
increases expression
ISO
nickel sulfate results in increased expression of GPR39 mRNA
CTD
PMID:22714537
NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267
G
Gpr4
G protein-coupled receptor 4
decreases expression
ISO
nickel sulfate results in decreased expression of GPR4 mRNA
CTD
PMID:22714537
NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
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Gprc5b
G protein-coupled receptor, class C, group 5, member B
increases expression
ISO
nickel sulfate results in increased expression of GPRC5B mRNA
CTD
PMID:22714537
NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932
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Gpt
glutamic--pyruvic transaminase
increases activity multiple interactions
EXP ISO
nickel sulfate results in increased activity of GPT protein puerarin inhibits the reaction [nickel sulfate results in increased activity of GPT protein] troxerutin inhibits the reaction [nickel sulfate results in increased activity of GPT protein]
CTD
PMID:24112957 PMID:26607348
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
nickel sulfate results in increased expression of GPX3 mRNA
CTD
PMID:20566472
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Gpx4
glutathione peroxidase 4
increases expression multiple interactions
ISO EXP
nickel sulfate results in increased expression of GPX4 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of GPX4 mRNA
CTD
PMID:18651567 PMID:31734292
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Gpx7
glutathione peroxidase 7
decreases expression
ISO
nickel sulfate results in decreased expression of GPX7 mRNA
CTD
PMID:22714537
NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
G
Gramd1c
GRAM domain containing 1C
increases expression
ISO
nickel sulfate results in increased expression of GRAMD1C mRNA
CTD
PMID:22714537
NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570
G
Grem1
gremlin 1, DAN family BMP antagonist
decreases expression
ISO
nickel sulfate results in decreased expression of GREM1 mRNA
CTD
PMID:22714537
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
G
Gse1
Gse1 coiled-coil protein
increases expression
ISO
nickel sulfate results in increased expression of GSE1 mRNA
CTD
PMID:22714537
NCBI chr19:48,274,164...48,629,456
Ensembl chr19:48,274,127...48,629,458
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
ISO
nickel sulfate results in increased expression of GSK3B mRNA
CTD
PMID:17374397
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsn
gelsolin
increases expression
ISO
nickel sulfate results in increased expression of GSN mRNA
CTD
PMID:18651567
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gspt2
G1 to S phase transition 2
decreases expression
ISO
nickel sulfate results in decreased expression of GSPT2 mRNA
CTD
PMID:22714537
NCBI chr X:59,587,237...59,589,758
Ensembl chr X:59,587,276...59,594,162
G
Gsr
glutathione-disulfide reductase
increases expression decreases activity multiple interactions
ISO EXP
nickel sulfate results in increased expression of GSR mRNA nickel sulfate results in decreased activity of GSR protein naringin inhibits the reaction [nickel sulfate results in decreased activity of GSR protein]
CTD
PMID:20566472 PMID:20950607
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gtf2b
general transcription factor IIB
increases expression
ISO
nickel sulfate results in increased expression of GTF2B mRNA
CTD
PMID:17374397
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
G
Gtpbp6
GTP binding protein 6 (putative)
increases expression
ISO
nickel sulfate results in increased expression of GTPBP6 mRNA
CTD
PMID:22714537
NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873
G
Guk1
guanylate kinase 1
increases expression
ISO
nickel sulfate results in increased expression of GUK1 mRNA
CTD
PMID:18651567
NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107
G
Gulp1
GULP PTB domain containing engulfment adaptor 1
increases expression
ISO
nickel sulfate results in increased expression of GULP1 mRNA
CTD
PMID:22714537
NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
G
Gzf1
GDNF-inducible zinc finger protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of GZF1 mRNA
CTD
PMID:22714537
NCBI chr 3:136,119,004...136,131,223
Ensembl chr 3:136,119,113...136,131,223
G
Gzmf
granzyme F
decreases expression
ISO
nickel sulfate results in decreased expression of GZMF mRNA
CTD
PMID:16166746
NCBI chr15:30,005,361...30,018,649
Ensembl chr15:30,007,267...30,018,649
G
H1f0
H1.0 linker histone
decreases expression
ISO
nickel sulfate results in decreased expression of H1-0 mRNA
CTD
PMID:22714537
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
G
H1f10
H1.10 linker histone
increases expression
ISO
nickel sulfate results in increased expression of H1-10 mRNA
CTD
PMID:18651567
NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448
G
H2ac18
H2A clustered histone 18
increases expression
ISO
nickel sulfate results in increased expression of H2AC18 mRNA
CTD
PMID:18651567
NCBI chr 2:183,808,398...183,808,992
G
H3f4
H3.4 histone, cluster member
increases methylation
ISO EXP
nickel sulfate results in increased methylation of H3-4 protein nickel sulfate results in increased methylation of H3F4 protein
CTD
PMID:19371620
NCBI chr10:43,740,702...43,741,262
G
H4cl1
histone H4C like 1
decreases expression
ISO
nickel sulfate results in decreased expression of H4C6 mRNA
CTD
PMID:22714537
NCBI chr17:41,368,743...41,426,735
G
Hacd4
3-hydroxyacyl-CoA dehydratase 4
decreases expression
ISO
nickel sulfate results in decreased expression of HACD4 mRNA
CTD
PMID:22714537
NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338
G
Hba-a1
hemoglobin alpha, adult chain 1
affects expression
ISO
nickel sulfate affects the expression of HBA-A1 mRNA
CTD
PMID:12718980
NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392
G
Hbb-b2
hemoglobin, beta adult minor chain
decreases expression
ISO
nickel sulfate results in decreased expression of HBB-B2 mRNA
CTD
PMID:16100012
NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012
G
Heatr5b
HEAT repeat containing 5B
decreases expression
ISO
nickel sulfate results in decreased expression of HEATR5B mRNA
CTD
PMID:17374397
NCBI chr 6:16,243,424...16,323,444
Ensembl chr 6:16,243,461...16,323,435
G
Herc4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
decreases expression
ISO
nickel sulfate results in decreased expression of HERC4 mRNA
CTD
PMID:16780908
NCBI chr20:25,329,972...25,404,657
Ensembl chr20:25,330,280...25,404,657
G
Herc6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
increases expression
ISO
nickel sulfate results in increased expression of HERC6 mRNA
CTD
PMID:22714537
NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744
G
Hes1
hes family bHLH transcription factor 1
increases expression
ISO
nickel sulfate results in increased expression of HES1 mRNA
CTD
PMID:22714537
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
G
Hif1a
hypoxia inducible factor 1 subunit alpha
increases expression increases stability decreases hydroxylation decreases expression multiple interactions
ISO
nickel sulfate results in increased expression of HIF1A mRNA; nickel sulfate results in increased expression of HIF1A protein nickel sulfate results in increased stability of HIF1A protein nickel sulfate results in decreased hydroxylation of HIF1A protein nickel sulfate results in decreased expression of HIF1A mRNA [chromium hexavalent ion co-treated with nickel sulfate] results in increased expression of HIF1A protein; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein]; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]; [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of HIF1A mRNA; [nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein; [potassium chromate(VI) co-treated with nickel sulfate] results in increased expression of HIF1A protein; [U 0126 co-treated with SB 203580] inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]; Dinoprostone promotes the reaction [nickel sulfate results in increased expression of and results in increased activity of HIF1A protein]; HIF1A mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 mRNA]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL5 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL8 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of VEGFA protein]; HIF1A protein promotes the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein]; macrophage stimulatory lipopeptide 2 co-treated with [nickel sulfate results in increased expression of HIF1A protein]; nickel sulfate affects the localization of and results in increased stability of HIF1A protein; nickel sulfate promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; nickel sulfate results in increased expression of and results in increased activity of HIF1A protein; SB 203580 inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]
CTD
PMID:16288478 PMID:16314067 PMID:17382205 PMID:18832182 PMID:19074761 PMID:20046830 PMID:20600219 PMID:23526216 PMID:23568779 More...
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hilpda
hypoxia inducible lipid droplet-associated
increases expression
ISO
nickel sulfate results in increased expression of HILPDA mRNA
CTD
PMID:17382205
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Hint3
histidine triad nucleotide binding protein 3
increases expression
ISO
nickel sulfate results in increased expression of HINT3 mRNA
CTD
PMID:22714537
NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721
G
Hip1
huntingtin interacting protein 1
increases expression
ISO
nickel sulfate results in increased expression of HIP1 mRNA
CTD
PMID:16780908
NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725
G
Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
nickel sulfate results in increased expression of HIPK2 mRNA
CTD
PMID:16314067
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
G
Hivep1
HIVEP zinc finger 1
increases expression
ISO
nickel sulfate results in increased expression of HIVEP1 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956
G
Hk2
hexokinase 2
decreases expression
ISO
nickel sulfate results in decreased expression of HK2 mRNA
CTD
PMID:22714537
NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
G
Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
nickel sulfate results in increased expression of HMGCS1 mRNA
CTD
PMID:22714537
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
G
Hmox1
heme oxygenase 1
increases expression multiple interactions decreases expression
ISO
nickel sulfate results in increased expression of HMOX1 mRNA Quercetin inhibits the reaction [nickel sulfate results in decreased expression of HMOX1 protein]
CTD
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20491607 PMID:20566472 PMID:25957741 More...
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
increases expression
ISO
nickel sulfate results in increased expression of HNRNPA1 mRNA
CTD
PMID:18651567
NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
G
Homer1
homer scaffold protein 1
increases expression
ISO
nickel sulfate results in increased expression of HOMER1 mRNA
CTD
PMID:22714537
NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
G
Hoxa1
homeobox A1
increases expression
ISO
nickel sulfate results in increased expression of HOXA1 mRNA
CTD
PMID:22714537
NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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Hoxa2
homeobox A2
increases expression
ISO
nickel sulfate results in increased expression of HOXA2 mRNA
CTD
PMID:22714537
NCBI chr 4:81,262,668...81,266,970
Ensembl chr 4:81,262,768...81,265,044
G
Hoxa3
homeobox A3
increases expression
ISO
nickel sulfate results in increased expression of HOXA3 mRNA
CTD
PMID:22714537
NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218
G
Hoxc10
homeo box C10
increases expression
ISO
nickel sulfate results in increased expression of HOXC10 mRNA
CTD
PMID:22714537
NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
G
Hoxc13
homeobox C13
increases expression
ISO
nickel sulfate results in increased expression of HOXC13 mRNA
CTD
PMID:22714537
NCBI chr 7:134,058,640...134,065,479
Ensembl chr 7:134,058,640...134,064,800
G
Hoxc9
homeobox C9
increases expression
ISO
nickel sulfate results in increased expression of HOXC9 mRNA
CTD
PMID:22714537
NCBI chr 7:134,118,817...134,121,497
Ensembl chr 7:134,118,817...134,121,492
G
Hpcal1
hippocalcin-like 1
increases expression
ISO
nickel sulfate results in increased expression of HPCAL1 mRNA
CTD
PMID:22714537
NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687
G
Hpgd
15-hydroxyprostaglandin dehydrogenase
decreases expression
ISO
nickel sulfate results in decreased expression of HPGD mRNA
CTD
PMID:18651567
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
ISO
nickel sulfate affects the expression of HPRT1 mRNA
CTD
PMID:18202158
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
increases expression
ISO
nickel sulfate results in increased expression of HPS5 mRNA
CTD
PMID:22714537
NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
G
Hs6st1
heparan sulfate 6-O-sulfotransferase 1
increases expression
ISO
nickel sulfate results in increased expression of HS6ST1 mRNA
CTD
PMID:22714537
NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683
G
Hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
multiple interactions decreases expression
EXP
[CGA protein co-treated with nickel sulfate] results in decreased expression of HSD17B3 mRNA; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]
CTD
PMID:29567110
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
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Hsd17b6
hydroxysteroid (17-beta) dehydrogenase 6
increases expression
ISO
nickel sulfate results in increased expression of HSD17B6 mRNA
CTD
PMID:22714537
NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
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Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of HSD17B7 mRNA
CTD
PMID:31734292
NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
G
Hsdl1
hydroxysteroid dehydrogenase like 1
increases expression
ISO
nickel sulfate results in increased expression of HSDL1 mRNA
CTD
PMID:22714537
NCBI chr19:47,615,794...47,631,892
Ensembl chr19:47,615,796...47,631,846
G
Hsf1
heat shock transcription factor 1
increases expression
ISO
nickel sulfate results in increased expression of HSF1 mRNA
CTD
PMID:18651567
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
G
Hspa12a
heat shock protein family A (Hsp70) member 12A
increases expression
ISO
nickel sulfate results in increased expression of HSPA12A mRNA
CTD
PMID:22714537
NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
ISO
nickel sulfate results in increased expression of HSPA1A mRNA
CTD
PMID:18651567
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein] nickel sulfate results in increased expression of HSPA5 mRNA; nickel sulfate results in increased expression of HSPA5 protein
CTD
PMID:28296042
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
nickel sulfate results in increased expression of HSPA6 mRNA
CTD
PMID:16314067
NCBI chr13:83,273,176...83,274,317
G
Hspb8
heat shock protein family B (small) member 8
increases expression
ISO
nickel sulfate results in increased expression of HSPB8 mRNA
CTD
PMID:22714537
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
G
Hspg2
heparan sulfate proteoglycan 2
decreases expression
ISO
nickel sulfate results in decreased expression of HSPG2 mRNA
CTD
PMID:22714537
NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
G
Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
nickel sulfate results in increased expression of HTATIP2 mRNA
CTD
PMID:16314067
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
G
Htr1d
5-hydroxytryptamine receptor 1D
increases expression
ISO
nickel sulfate results in increased expression of HTR1D mRNA
CTD
PMID:22714537
NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619
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Htr7
5-hydroxytryptamine receptor 7
decreases expression
ISO
nickel sulfate results in decreased expression of HTR7 mRNA
CTD
PMID:22714537
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
G
Icam1
intercellular adhesion molecule 1
increases expression affects expression
EXP ISO
nickel sulfate results in increased expression of ICAM1 mRNA nickel sulfate results in increased expression of ICAM1 protein nickel sulfate affects the expression of ICAM1 mRNA
CTD
PMID:11114790 PMID:18202158 PMID:19702435 PMID:20417223 PMID:29540657
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Id1
inhibitor of DNA binding 1
increases expression
ISO
nickel sulfate results in increased expression of ID1 mRNA
CTD
PMID:18651567
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
G
Id2
inhibitor of DNA binding 2
increases expression
ISO
nickel sulfate results in increased expression of ID2 mRNA
CTD
PMID:16780908 PMID:20146380
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
G
Id3
inhibitor of DNA binding 3
increases expression
ISO
nickel sulfate results in increased expression of ID3 mRNA
CTD
PMID:22714537
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
G
Id4
inhibitor of DNA binding 4
increases expression
ISO
nickel sulfate results in increased expression of ID4 mRNA
CTD
PMID:22714537
NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
G
Idh3b
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
decreases expression
ISO
nickel sulfate results in decreased expression of IDH3B mRNA
CTD
PMID:22714537
NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
G
Ido1
indoleamine 2,3-dioxygenase 1
increases expression
ISO
nickel sulfate results in increased expression of IDO1 mRNA
CTD
PMID:16780908
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
G
Ids
iduronate 2-sulfatase
decreases expression
ISO
nickel sulfate results in decreased expression of IDS mRNA
CTD
PMID:22714537
NCBI chr X:149,025,976...149,046,641
Ensembl chr X:149,025,976...149,046,663
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Ier2
immediate early response 2
increases expression
ISO
nickel sulfate results in increased expression of IER2 mRNA
CTD
PMID:16780908
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
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Ier3
immediate early response 3
increases expression
ISO
nickel sulfate results in increased expression of IER3 mRNA
CTD
PMID:17374397 PMID:18651567 PMID:22714537
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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Ifi30
IFI30, lysosomal thiol reductase
increases expression
ISO
nickel sulfate results in increased expression of IFI30 mRNA
CTD
PMID:22714537
NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175
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Ifi44
interferon-induced protein 44
increases expression
ISO
nickel sulfate results in increased expression of IFI44 mRNA
CTD
PMID:22714537
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
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Ifih1
interferon induced with helicase C domain 1
increases expression
ISO
nickel sulfate results in increased expression of IFIH1 mRNA
CTD
PMID:22714537
NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
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Ifit2
interferon-induced protein with tetratricopeptide repeats 2
decreases expression
ISO
nickel sulfate results in decreased expression of IFIT2 mRNA
CTD
PMID:17374397
NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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Ifitm1
interferon induced transmembrane protein 1
increases expression
ISO
nickel sulfate results in increased expression of IFITM1 mRNA
CTD
PMID:22714537
NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
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Ifnb1
interferon beta 1
increases expression
ISO
nickel sulfate results in increased expression of IFNB1 mRNA
CTD
PMID:20525893
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Ifne
interferon, epsilon
decreases expression
ISO
nickel sulfate results in decreased expression of IFNE mRNA
CTD
PMID:22714537
NCBI chr 5:103,571,630...103,572,290
Ensembl chr 5:103,569,675...103,572,256
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Ifng
interferon gamma
multiple interactions increases secretion affects expression increases expression
ISO
[nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Cholecalciferol inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Dimethyl Fumarate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Hydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; IFNG protein promotes the reaction [nickel sulfate results in increased expression of IL27 mRNA]; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein] nickel sulfate affects the expression of IFNG mRNA nickel sulfate results in increased expression of IFNG mRNA
CTD
PMID:10929769 PMID:11145678 PMID:14650623 PMID:15270870 PMID:15663561 PMID:16166746 PMID:29594315 PMID:30421605 More...
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Ifrd1
interferon-related developmental regulator 1
increases expression
ISO
nickel sulfate results in increased expression of IFRD1 mRNA
CTD
PMID:17374397
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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Ift56
intraflagellar transport 56
increases expression
ISO
nickel sulfate results in increased expression of IFT56 mRNA
CTD
PMID:22714537
NCBI chr 4:67,090,622...67,154,707
Ensembl chr 4:67,090,660...67,147,903
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Ift70a2
intraflagellar transport 70A2
increases expression
ISO
nickel sulfate results in increased expression of IFT70A mRNA
CTD
PMID:22714537
NCBI chr 3:60,899,193...60,901,634
Ensembl chr 3:60,899,196...60,901,634
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Ift88
intraflagellar transport 88
decreases expression
ISO
nickel sulfate results in decreased expression of IFT88 mRNA
CTD
PMID:22714537
NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147
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Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of IGF2BP1 mRNA
CTD
PMID:22714537
NCBI chr10:80,908,300...80,951,097
Ensembl chr10:80,908,076...80,951,129
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Igfbp4
insulin-like growth factor binding protein 4
decreases expression
ISO
nickel sulfate results in decreased expression of IGFBP4 mRNA
CTD
PMID:22714537
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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Igfbp6
insulin-like growth factor binding protein 6
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of IGFBP6 mRNA nickel sulfate results in increased expression of IGFBP6 mRNA
CTD
PMID:16100012 PMID:16780908 PMID:17374397
NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
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Il10
interleukin 10
increases secretion increases expression
ISO
nickel sulfate results in increased secretion of IL10 protein nickel sulfate results in increased expression of IL10 mRNA
CTD
PMID:11145678 PMID:15347381
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il11
interleukin 11
decreases expression
ISO
nickel sulfate results in decreased expression of IL11 mRNA
CTD
PMID:22714537
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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Il12a
interleukin 12A
increases expression
ISO
nickel sulfate results in increased expression of IL12A mRNA
CTD
PMID:30421605
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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Il12b
interleukin 12B
affects expression increases expression increases secretion multiple interactions
ISO
nickel sulfate affects the expression of IL12B mRNA nickel sulfate results in increased expression of IL12B mRNA; nickel sulfate results in increased expression of IL12B protein nickel sulfate results in increased secretion of IL12B protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [nickel sulfate results in increased secretion of IL12B protein]; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]
CTD
PMID:17636246 PMID:18202158 PMID:19101624 PMID:20525893 PMID:25673294 PMID:30421605 More...
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il13ra1
interleukin 13 receptor subunit alpha 1
increases expression
ISO
nickel sulfate results in increased expression of IL13RA1 mRNA
CTD
PMID:22714537
NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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Il15
interleukin 15
affects expression
ISO
nickel sulfate affects the expression of IL15 mRNA
CTD
PMID:18202158
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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Il18
interleukin 18
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of IL18 mRNA nickel sulfate results in increased expression of IL18 protein
CTD
PMID:18651567 PMID:23063874
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
increases secretion multiple interactions
ISO
nickel sulfate results in increased secretion of IL1A protein IL1A protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]; IL1A protein affects the reaction [nickel sulfate results in increased secretion of CXCL8 protein]
CTD
PMID:15679580
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
increases expression decreases expression multiple interactions increases secretion
EXP ISO
nickel sulfate results in increased expression of IL1B mRNA nickel sulfate results in decreased expression of IL1B mRNA Quercetin inhibits the reaction [nickel sulfate results in increased expression of IL1B protein] nickel sulfate results in increased expression of IL1B mRNA; nickel sulfate results in increased expression of IL1B protein [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL1B protein; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IL1B protein]
CTD
PMID:11033066 PMID:11114790 PMID:11751209 PMID:14650623 PMID:16166746 PMID:16314067 PMID:16780908 PMID:19702435 PMID:20713136 PMID:21697260 PMID:24964617 PMID:25673294 PMID:25957741 PMID:29594315 PMID:30842373 More...
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1r1
interleukin 1 receptor type 1
increases expression
ISO
nickel sulfate results in increased expression of IL1R1 mRNA
CTD
PMID:22714537
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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Il1r2
interleukin 1 receptor type 2
increases expression
ISO
nickel sulfate results in increased expression of IL1R2 mRNA
CTD
PMID:16166746 PMID:16780908
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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Il1rn
interleukin 1 receptor antagonist
increases expression
ISO
nickel sulfate results in increased expression of IL1RN mRNA
CTD
PMID:16166746 PMID:16780908
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il2
interleukin 2
increases secretion multiple interactions increases expression
ISO
nickel sulfate results in increased secretion of IL2 protein [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA nickel sulfate results in increased expression of IL2 protein
CTD
PMID:12925207 PMID:22381623 PMID:29594315
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il23a
interleukin 23 subunit alpha
increases expression
ISO
nickel sulfate results in increased expression of IL23A mRNA
CTD
PMID:30421605
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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Il24
interleukin 24
decreases expression
ISO
nickel sulfate results in decreased expression of IL24 mRNA
CTD
PMID:22714537
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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Il27
interleukin 27
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of IL27 mRNA BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of IL27 mRNA]; IFNG protein promotes the reaction [nickel sulfate results in increased expression of IL27 mRNA]; Janus Kinase Inhibitors inhibits the reaction [nickel sulfate results in increased secretion of IL27 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of IL27 mRNA]; TLR4 protein affects the reaction [nickel sulfate results in increased expression of IL27 mRNA]
CTD
PMID:30421605
NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
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Il4
interleukin 4
increases secretion increases expression
ISO
nickel sulfate results in increased secretion of IL4 protein nickel sulfate results in increased expression of IL4 mRNA
CTD
PMID:10929769 PMID:11145678
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il4r
interleukin 4 receptor
increases expression
ISO
nickel sulfate results in increased expression of IL4RA mRNA; nickel sulfate results in increased expression of IL4RA protein
CTD
PMID:16100012 PMID:22381623
NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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Il5
interleukin 5
multiple interactions increases secretion
ISO
Cyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]; Diclofenac inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]; Hydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]
CTD
PMID:10929769 PMID:15270870 PMID:15347381 PMID:15663561 PMID:19572476
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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Il6
interleukin 6
increases expression multiple interactions increases secretion
EXP ISO
nickel sulfate results in increased expression of IL6 mRNA nickel sulfate results in increased expression of IL6 mRNA; nickel sulfate results in increased expression of IL6 protein puerarin inhibits the reaction [nickel sulfate results in increased expression of IL6 protein] nickel sulfate results in increased secretion of IL6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of IL6 mRNA; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of IL6 mRNA; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL6 protein; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; HIF1A mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; nickel sulfate results in increased expression of and results in increased secretion of IL6 protein; PTGS2 mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in increased expression of IL6 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of IL6 protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; U 0126 inhibits the reaction [nickel sulfate results in increased expression of IL6 protein]
CTD
PMID:11033066 PMID:11114790 PMID:16166746 PMID:16780908 PMID:17118622 PMID:17636246 PMID:17763283 PMID:18832182 PMID:19101624 PMID:20600219 PMID:22714537 PMID:24964617 PMID:25673294 PMID:26607348 PMID:35499276 More...
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Il7r
interleukin 7 receptor
increases expression
ISO
nickel sulfate results in increased expression of IL7R mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
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Ildr2
immunoglobulin-like domain containing receptor 2
decreases expression
ISO
nickel sulfate results in decreased expression of ILDR2 mRNA
CTD
PMID:22714537
NCBI chr13:78,518,770...78,580,627
Ensembl chr13:78,518,802...78,576,924
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Ilrun
inflammation and lipid regulator with UBA-like and NBR1-like domains
increases expression
ISO
nickel sulfate results in increased expression of ILRUN mRNA
CTD
PMID:22714537
NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012
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Impa2
inositol monophosphatase 2
increases expression
ISO
nickel sulfate results in increased expression of IMPA2 mRNA
CTD
PMID:22714537
NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
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Inhba
inhibin subunit beta A
increases expression
ISO
nickel sulfate results in increased expression of INHBA mRNA
CTD
PMID:16780908
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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Insig2
insulin induced gene 2
increases expression
ISO
nickel sulfate results in increased expression of INSIG2 mRNA
CTD
PMID:17382205
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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Insm1
INSM transcriptional repressor 1
increases expression
ISO
nickel sulfate results in increased expression of INSM1 mRNA
CTD
PMID:16780908
NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003
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Ints2
integrator complex subunit 2
increases expression
ISO
nickel sulfate results in increased expression of INTS2 mRNA
CTD
PMID:22714537
NCBI chr10:71,031,647...71,079,138
Ensembl chr10:71,031,647...71,079,076
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Ipcef1
interaction protein for cytohesin exchange factors 1
decreases expression
ISO
nickel sulfate results in decreased expression of IPCEF1 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 1:43,237,903...43,451,735
Ensembl chr 1:43,269,202...43,427,969
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Iqck
IQ motif containing K
increases expression
ISO
nickel sulfate results in increased expression of IQCK mRNA
CTD
PMID:22714537
NCBI chr 1:173,199,308...173,316,982
Ensembl chr 1:173,199,316...173,316,984
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Iqgap2
IQ motif containing GTPase activating protein 2
increases expression
ISO
nickel sulfate results in increased expression of IQGAP2 mRNA
CTD
PMID:22714537
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
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Irf1
interferon regulatory factor 1
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of IRF1 mRNA; nickel sulfate results in increased expression of IRF1 protein Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of IRF1 protein]; Puromycin inhibits the reaction [nickel sulfate results in increased expression of IRF1 protein]
CTD
PMID:20525893
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Irf5
interferon regulatory factor 5
increases expression
ISO
nickel sulfate results in increased expression of IRF5 mRNA
CTD
PMID:16780908
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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Irf8
interferon regulatory factor 8
increases expression
ISO
nickel sulfate results in increased expression of IRF8 mRNA
CTD
PMID:22714537
NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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Irx4
iroquois homeobox 4
increases expression
ISO
nickel sulfate results in increased expression of IRX4 mRNA
CTD
PMID:22714537
NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549
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Irx5
iroquois homeobox 5
decreases expression
ISO
nickel sulfate results in decreased expression of IRX5 mRNA
CTD
PMID:16100012
NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318
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Isyna1
inositol-3-phosphate synthase 1
decreases expression
ISO
nickel sulfate results in decreased expression of ISYNA1 mRNA
CTD
PMID:22714537
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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Itga7
integrin subunit alpha 7
decreases expression
ISO
nickel sulfate results in decreased expression of ITGA7 mRNA
CTD
PMID:22714537
NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450
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Itgb3
integrin subunit beta 3
increases expression
ISO
nickel sulfate results in increased expression of ITGB3 mRNA
CTD
PMID:16780908
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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Itgb4
integrin subunit beta 4
increases expression
ISO
nickel sulfate results in increased expression of ITGB4 mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
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Itpa
inosine triphosphatase
decreases expression
ISO
nickel sulfate results in decreased expression of ITPA mRNA
CTD
PMID:22714537
NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249
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Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
increases expression
ISO
nickel sulfate results in increased expression of ITPR3 mRNA
CTD
PMID:22714537
NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
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Itprid2
ITPR interacting domain containing 2
increases expression
ISO
nickel sulfate results in increased expression of ITPRID2 mRNA
CTD
PMID:22714537
NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
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Ivns1abp
influenza virus NS1A binding protein
decreases expression
ISO
nickel sulfate results in decreased expression of IVNS1ABP mRNA
CTD
PMID:22714537
NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
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Jhy
junctional cadherin complex regulator
increases expression
ISO
nickel sulfate results in increased expression of JHY mRNA
CTD
PMID:22714537
NCBI chr 8:41,276,501...41,333,383
Ensembl chr 8:41,276,491...41,333,514
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Jmjd6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
increases expression
ISO
nickel sulfate results in increased expression of JMJD6 mRNA
CTD
PMID:16166746
NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
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Jmjd8
jumonji domain containing 8
decreases expression
ISO
nickel sulfate results in decreased expression of JMJD8 mRNA
CTD
PMID:22714537
NCBI chr10:14,848,965...14,851,881
Ensembl chr10:14,848,980...14,851,879
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Jrkl
JRK-like
decreases expression
ISO
nickel sulfate results in decreased expression of JRKL mRNA
CTD
PMID:22714537
NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases activity increases phosphorylation multiple interactions increases expression
ISO
nickel sulfate results in increased activity of JUN protein nickel sulfate results in increased phosphorylation of JUN protein Potassium Dichromate inhibits the reaction [nickel sulfate results in increased phosphorylation of JUN protein] nickel sulfate results in increased expression of JUN mRNA
CTD
PMID:16314067 PMID:17382205 PMID:19131640 PMID:20493934
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
nickel sulfate results in increased expression of JUNB mRNA
CTD
PMID:16166746 PMID:16780908 PMID:18651567 PMID:19131640
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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Jund
JunD proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
nickel sulfate results in increased expression of JUND mRNA
CTD
PMID:19131640
NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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Jup
junction plakoglobin
decreases expression
ISO
nickel sulfate results in decreased expression of JUP mRNA
CTD
PMID:22714537
NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
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Kat14
lysine acetyltransferase 14
decreases expression
ISO
nickel sulfate results in decreased expression of KAT14 mRNA
CTD
PMID:22714537
NCBI chr 3:131,736,430...131,781,732
Ensembl chr 3:131,736,549...131,781,706
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Kcng1
potassium voltage-gated channel modifier subfamily G member 1
increases expression
ISO
nickel sulfate results in increased expression of KCNG1 mRNA
CTD
PMID:22714537
NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
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Kcng3
potassium voltage-gated channel modifier subfamily G member 3
increases expression
ISO
nickel sulfate results in increased expression of KCNG3 mRNA
CTD
PMID:22714537
NCBI chr 6:11,051,311...11,099,264
Ensembl chr 6:11,051,134...11,099,264
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Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
decreases expression
ISO
nickel sulfate results in decreased expression of KCNJ10 mRNA
CTD
PMID:16780908
NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461
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Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
decreases expression
ISO
nickel sulfate results in decreased expression of KCNJ2 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
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Kctd13
potassium channel tetramerization domain containing 13
increases expression
ISO
nickel sulfate results in increased expression of KCTD13 mRNA
CTD
PMID:22714537
NCBI chr 1:181,534,534...181,552,843
Ensembl chr 1:181,534,515...181,552,881
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Kctd15
potassium channel tetramerization domain containing 15
decreases expression
ISO
nickel sulfate results in decreased expression of KCTD15 mRNA
CTD
PMID:16780908
NCBI chr 1:87,258,658...87,271,979
Ensembl chr 1:87,258,658...87,273,497
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Kctd4
potassium channel tetramerization domain containing 4
decreases expression
ISO
nickel sulfate results in decreased expression of KCTD4 mRNA
CTD
PMID:22714537
NCBI chr15:51,263,664...51,278,030
Ensembl chr15:51,274,295...51,277,499
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Kdm3a
lysine demethylase 3A
increases expression
ISO
nickel sulfate results in increased expression of KDM3A protein
CTD
PMID:23546878
NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
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Kif16b
kinesin family member 16B
decreases expression
ISO
nickel sulfate results in decreased expression of KIF16B mRNA
CTD
PMID:22714537
NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
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Kif1b
kinesin family member 1B
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of KIF1B mRNA
CTD
PMID:31734292
NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
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Kif20b
kinesin family member 20B
decreases expression
ISO
nickel sulfate results in decreased expression of KIF20B mRNA
CTD
PMID:22714537
NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
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Kif5c
kinesin family member 5C
increases expression
ISO
nickel sulfate results in increased expression of KIF5C mRNA
CTD
PMID:22714537
NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
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Kifap3
kinesin-associated protein 3
decreases expression
ISO
nickel sulfate results in decreased expression of KIFAP3 mRNA
CTD
PMID:22714537
NCBI chr13:76,127,702...76,264,654
Ensembl chr13:76,127,696...76,264,650
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Kirrel3
kirre like nephrin family adhesion molecule 3
decreases expression
ISO
nickel sulfate results in decreased expression of KIRREL3 mRNA
CTD
PMID:22714537
NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676
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Kit
KIT proto-oncogene receptor tyrosine kinase
decreases expression
ISO
nickel sulfate results in decreased expression of KIT mRNA
CTD
PMID:22714537
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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Kitlg
KIT ligand
decreases expression
ISO
nickel sulfate results in decreased expression of KITLG mRNA
CTD
PMID:22714537
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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Kiz
kizuna centrosomal protein
decreases expression
ISO
nickel sulfate results in decreased expression of KIZ mRNA
CTD
PMID:22714537
NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190
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Klb
klotho beta
decreases expression
ISO
nickel sulfate results in decreased expression of KLB mRNA
CTD
PMID:16100012
NCBI chr14:42,899,050...42,950,788
Ensembl chr14:42,899,510...42,950,799
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Klf11
KLF transcription factor 11
increases expression
ISO
nickel sulfate results in increased expression of KLF11 mRNA
CTD
PMID:22714537
NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
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Klf4
KLF transcription factor 4
decreases expression
ISO
nickel sulfate results in decreased expression of KLF4 mRNA
CTD
PMID:16780908
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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Klf6
KLF transcription factor 6
increases expression
ISO
nickel sulfate results in increased expression of KLF6 mRNA
CTD
PMID:16314067 PMID:17374397
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Klhl36
kelch-like family member 36
increases expression
ISO
nickel sulfate results in increased expression of KLHL36 mRNA
CTD
PMID:22714537
NCBI chr19:47,921,590...47,942,627
Ensembl chr19:47,921,590...47,942,620
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Klk10
kallikrein related-peptidase 10
increases expression
ISO
nickel sulfate results in increased expression of KLK10 mRNA
CTD
PMID:18651567
NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376
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Klk8
kallikrein related-peptidase 8
decreases activity
ISO
nickel sulfate results in decreased activity of KLK8 protein
CTD
PMID:16800733
NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
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Kremen1
kringle containing transmembrane protein 1
increases expression
ISO
nickel sulfate results in increased expression of KREMEN1 mRNA
CTD
PMID:22714537
NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516
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Krr1
KRR1, small subunit processome component homolog
decreases expression
ISO
nickel sulfate results in decreased expression of KRR1 mRNA
CTD
PMID:16780908
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
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Krt17
keratin 17
decreases expression
ISO
nickel sulfate results in decreased expression of KRT17 mRNA
CTD
PMID:22714537
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
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Krt7
keratin 7
affects expression
ISO
nickel sulfate affects the expression of KRT7 mRNA
CTD
PMID:12718980
NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
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Kynu
kynureninase
increases expression
ISO
nickel sulfate results in increased expression of KYNU mRNA
CTD
PMID:22714537
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
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Lad1
ladinin 1
increases expression
ISO
nickel sulfate results in increased expression of LAD1 mRNA
CTD
PMID:16780908
NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967
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Lama4
laminin subunit alpha 4
increases expression
ISO
nickel sulfate results in increased expression of LAMA4 mRNA
CTD
PMID:22714537
NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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Lamb3
laminin subunit beta 3
decreases expression
ISO
nickel sulfate results in decreased expression of LAMB3 mRNA
CTD
PMID:22714537
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
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Lamc1
laminin subunit gamma 1
decreases expression
ISO
nickel sulfate results in decreased expression of LAMC1 mRNA
CTD
PMID:22714537
NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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Lamc2
laminin subunit gamma 2
decreases expression
ISO
nickel sulfate results in decreased expression of LAMC2 mRNA
CTD
PMID:22714537
NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
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Lamp3
lysosomal-associated membrane protein 3
increases expression
ISO
nickel sulfate results in increased expression of LAMP3 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
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Lbr
lamin B receptor
decreases expression
ISO
nickel sulfate results in decreased expression of LBR mRNA
CTD
PMID:22714537
NCBI chr13:93,539,386...93,564,026
Ensembl chr13:93,538,920...93,564,017
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Lcn2
lipocalin 2
increases expression
ISO
nickel sulfate results in increased expression of LCN2 mRNA
CTD
PMID:16100012
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Lep
leptin
multiple interactions increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of LEP mRNA nickel sulfate results in increased expression of LEP mRNA
CTD
PMID:18832182
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lepr
leptin receptor
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of LEPR mRNA
CTD
PMID:31734292
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Lgals3
galectin 3
affects expression decreases expression
ISO
nickel sulfate affects the expression of LGALS3 mRNA nickel sulfate results in decreased expression of LGALS3 mRNA
CTD
PMID:12718980 PMID:18651567
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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Lgals8
galectin 8
decreases expression
ISO
nickel sulfate results in decreased expression of LGALS8 mRNA
CTD
PMID:16780908
NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
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Lhx2
LIM homeobox 2
increases expression
ISO
nickel sulfate results in increased expression of LHX2 mRNA
CTD
PMID:22714537
NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908
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Lif
LIF, interleukin 6 family cytokine
decreases expression
ISO
nickel sulfate results in decreased expression of LIF mRNA
CTD
PMID:22714537
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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Lifr
LIF receptor subunit alpha
increases expression
ISO
nickel sulfate results in increased expression of LIFR mRNA
CTD
PMID:22714537
NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
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Lig1
DNA ligase 1
increases expression
ISO
nickel sulfate results in increased expression of LIG1 mRNA
CTD
PMID:16100012
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
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Lilrb4
leukocyte immunoglobulin like receptor B4
increases expression
ISO
nickel sulfate results in increased expression of LILRB4 mRNA; nickel sulfate results in increased expression of LILRB4B mRNA
CTD
PMID:16100012
NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
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Lins1
lines homolog 1
decreases expression
ISO
nickel sulfate results in decreased expression of LINS1 mRNA
CTD
PMID:16780908
NCBI chr 1:120,267,586...120,295,013
Ensembl chr 1:120,267,693...120,293,607
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Liph
lipase H
increases expression
ISO
nickel sulfate results in increased expression of LIPH mRNA
CTD
PMID:22714537
NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625
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Litaf
lipopolysaccharide-induced TNF factor
increases expression decreases expression
ISO
nickel sulfate results in increased expression of LITAF mRNA nickel sulfate results in decreased expression of LITAF mRNA
CTD
PMID:16100012 PMID:18651567
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
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Llgl2
LLGL scribble cell polarity complex component 2
increases expression
ISO
nickel sulfate results in increased expression of LLGL2 mRNA
CTD
PMID:22714537
NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525
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Lmbr1
limb development membrane protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of LMBR1 mRNA
CTD
PMID:22714537
NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368
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Lmx1b
LIM homeobox transcription factor 1 beta
increases expression
ISO
nickel sulfate results in increased expression of LMX1B mRNA
CTD
PMID:22714537
NCBI chr 3:16,862,195...16,940,899
Ensembl chr 3:16,862,195...16,940,899
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LOC120096784
small nucleolar RNA SNORA5
increases expression
ISO
nickel sulfate results in increased expression of SNORA5A mRNA
CTD
PMID:22714537
NCBI chr14:81,486,718...81,486,846
Ensembl chr14:81,486,718...81,486,846
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LOC120098360
small nucleolar RNA SNORA13
decreases expression
ISO
nickel sulfate results in decreased expression of SNORA13 mRNA
CTD
PMID:22714537
NCBI chr18:25,404,452...25,404,585
Ensembl chr18:25,404,452...25,404,585
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LOC120103107
PRAME family member 12-like
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF585B mRNA
CTD
PMID:22714537
NCBI chr 5:156,009,794...156,012,390
Ensembl chr 5:156,009,836...156,012,357
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Lox
lysyl oxidase
increases expression decreases expression
ISO
nickel sulfate results in increased expression of LOX mRNA nickel sulfate results in decreased expression of LOX mRNA
CTD
PMID:17382205 PMID:22714537
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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Lpar3
lysophosphatidic acid receptor 3
increases expression
ISO
nickel sulfate results in increased expression of LPAR3 mRNA
CTD
PMID:22714537
NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357
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Lpar6
lysophosphatidic acid receptor 6
decreases expression
ISO
nickel sulfate results in decreased expression of LPAR6 mRNA
CTD
PMID:16780908
NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
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Lpcat1
lysophosphatidylcholine acyltransferase 1
increases expression
ISO
nickel sulfate results in increased expression of LPCAT1 mRNA
CTD
PMID:22714537
NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
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Lrat
lecithin retinol acyltransferase
decreases expression
ISO
nickel sulfate results in decreased expression of LRAT mRNA
CTD
PMID:16100012
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
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Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
increases expression
ISO
nickel sulfate results in increased expression of LRIG3 mRNA
CTD
PMID:22714537
NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481
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Lrp12
LDL receptor related protein 12
decreases expression
ISO
nickel sulfate results in decreased expression of LRP12 mRNA
CTD
PMID:22714537
NCBI chr 7:70,941,068...71,012,409
Ensembl chr 7:70,941,068...71,012,441
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Lrrk1
leucine-rich repeat kinase 1
increases expression
ISO
nickel sulfate results in increased expression of LRRK1 mRNA
CTD
PMID:22714537
NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
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Lsp1
lymphocyte-specific protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of LSP1 mRNA
CTD
PMID:22714537
NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416
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Lsr
lipolysis stimulated lipoprotein receptor
increases expression
ISO
nickel sulfate results in increased expression of LSR mRNA
CTD
PMID:18651567
NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952
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Ltbp2
latent transforming growth factor beta binding protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of LTBP2 mRNA
CTD
PMID:22714537
NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
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Luc7l3
LUC7-like 3 pre-mRNA splicing factor
decreases expression
ISO
nickel sulfate results in decreased expression of CROP mRNA
CTD
PMID:16780908
NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538
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Lurap1l
leucine rich adaptor protein 1-like
increases expression
ISO
nickel sulfate results in increased expression of LURAP1L mRNA
CTD
PMID:22714537
NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
increases expression
ISO
nickel sulfate results in increased expression of LYN mRNA
CTD
PMID:22714537
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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Lypd1
Ly6/Plaur domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of LYPD1 mRNA
CTD
PMID:22714537
NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493
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Lypd6
Ly6/Plaur domain containing 6
increases expression
ISO
nickel sulfate results in increased expression of LYPD6 mRNA
CTD
PMID:22714537
NCBI chr 3:34,487,425...34,632,887
Ensembl chr 3:34,496,485...34,630,308
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Lypd6b
Ly6/Plaur domain containing 6B
increases expression
ISO
nickel sulfate results in increased expression of LYPD6B mRNA
CTD
PMID:22714537
NCBI chr 3:34,199,101...34,360,770
Ensembl chr 3:34,199,599...34,360,770
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Maf
MAF bZIP transcription factor
decreases expression
ISO
nickel sulfate results in decreased expression of MAF mRNA
CTD
PMID:16780908
NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
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Maff
MAF bZIP transcription factor F
increases expression
ISO
nickel sulfate results in increased expression of MAFF mRNA
CTD
PMID:16166746 PMID:18651567 PMID:20566472
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
nickel sulfate results in increased expression of MAFG mRNA
CTD
PMID:20566472
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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Mafk
MAF bZIP transcription factor K
increases expression
ISO
nickel sulfate results in increased expression of MAFK mRNA
CTD
PMID:17374397 PMID:20566472
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of MAGI1 mRNA
CTD
PMID:22714537
NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691
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Magi3
membrane associated guanylate kinase, WW and PDZ domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of MAGI3 mRNA
CTD
PMID:22714537
NCBI chr 2:191,514,726...191,717,048
Ensembl chr 2:191,518,506...191,716,735
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Man2a1
mannosidase, alpha, class 2A, member 1
decreases expression
ISO
nickel sulfate results in decreased expression of MAN2A1 mRNA
CTD
PMID:22714537
NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349
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Maoa
monoamine oxidase A
increases expression
ISO
nickel sulfate results in increased expression of MAOA mRNA
CTD
PMID:16780908
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
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Map2k3
mitogen activated protein kinase kinase 3
increases phosphorylation
EXP
nickel sulfate results in increased phosphorylation of MAP2K3 protein
CTD
PMID:29567110
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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Map2k7
mitogen activated protein kinase kinase 7
increases phosphorylation
EXP
nickel sulfate results in increased phosphorylation of MAP2K7 protein
CTD
PMID:29567110
NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
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Map3k1
mitogen-activated protein kinase kinase kinase 1
affects response to substance decreases expression multiple interactions
ISO
MAP3K1 protein affects the susceptibility to nickel sulfate nickel sulfate results in decreased expression of MAP3K1 mRNA [MAP3K1 protein co-treated with MAP3K2 protein] affects the susceptibility to nickel sulfate; MAP3K1 protein affects the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]
CTD
PMID:18467339 PMID:22714537
NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
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Map3k14
mitogen-activated protein kinase kinase kinase 14
increases expression
ISO
nickel sulfate results in increased expression of MAP3K14 mRNA
CTD
PMID:16780908
NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
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Map3k2
mitogen activated protein kinase kinase kinase 2
multiple interactions
ISO
[MAP3K1 protein co-treated with MAP3K2 protein] affects the susceptibility to nickel sulfate
CTD
PMID:18467339
NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
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Map3k5
mitogen-activated protein kinase kinase kinase 5
increases expression
ISO
nickel sulfate results in increased expression of MAP3K5 mRNA
CTD
PMID:22714537
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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Map3k7cl
MAP3K7 C-terminal like
increases expression
ISO
nickel sulfate results in increased expression of MAP3K7CL mRNA
CTD
PMID:17382205
NCBI chr11:26,791,044...26,835,605
Ensembl chr11:26,791,316...26,835,602
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
ISO EXP
[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased phosphorylation of MAPK1 protein; U 0126 inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK1 protein]
CTD
PMID:15588916 PMID:18495191 PMID:19101624 PMID:19135467 PMID:20600219 PMID:29567110 PMID:35499276 More...
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk13
mitogen activated protein kinase 13
decreases expression
ISO
nickel sulfate results in decreased expression of MAPK13 mRNA
CTD
PMID:22714537
NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
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Mapk14
mitogen activated protein kinase 14
multiple interactions increases phosphorylation
EXP ISO
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MAPK14 mRNA nickel sulfate results in increased phosphorylation of MAPK14 protein
CTD
PMID:31734292 PMID:35499276
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
ISO EXP
[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased phosphorylation of MAPK3 protein; U 0126 inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK3 protein]
CTD
PMID:15588916 PMID:18495191 PMID:19101624 PMID:19135467 PMID:20600219 PMID:29567110 More...
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions increases phosphorylation
ISO
pyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]; SB 203580 promotes the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] MAP3K1 protein affects the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]
CTD
PMID:15588916 PMID:18467339 PMID:18495191 PMID:19101624 PMID:35499276
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
increases phosphorylation
ISO
nickel sulfate results in increased phosphorylation of MAPK9 protein
CTD
PMID:15588916 PMID:19101624
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Mapkapk2
MAPK activated protein kinase 2
multiple interactions
ISO
[Potassium Dichromate co-treated with nickel sulfate] results in increased phosphorylation of MAPKAPK2 protein
CTD
PMID:20493934
NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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Mapkapk3
MAPK activated protein kinase 3
increases expression
ISO
nickel sulfate results in increased expression of MAPKAPK3 mRNA
CTD
PMID:18651567
NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
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Mapt
microtubule-associated protein tau
decreases expression
ISO
nickel sulfate results in decreased expression of MAPT mRNA
CTD
PMID:16100012
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Marcks
myristoylated alanine rich protein kinase C substrate
increases expression
ISO
nickel sulfate results in increased expression of MARCKS mRNA
CTD
PMID:16314067
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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Marveld2
MARVEL domain containing 2
increases expression
ISO
nickel sulfate results in increased expression of MARVELD2 mRNA
CTD
PMID:22714537
NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150
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Matn3
matrilin 3
increases expression
ISO
nickel sulfate results in increased expression of MATN3 mRNA
CTD
PMID:22714537
NCBI chr 6:31,748,517...31,768,564
Ensembl chr 6:31,748,474...31,768,101
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Mboat1
membrane bound O-acyltransferase domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of MBOAT1 mRNA
CTD
PMID:22714537
NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088
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Mcc
MCC regulator of WNT signaling pathway
decreases expression
ISO
nickel sulfate results in decreased expression of MCC mRNA
CTD
PMID:22714537
NCBI chr18:36,794,206...37,266,237
Ensembl chr18:36,798,372...37,266,819
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Mcm8
minichromosome maintenance 8 homologous recombination repair factor
decreases expression
ISO
nickel sulfate results in decreased expression of MCM8 mRNA
CTD
PMID:22714537
NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008
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Mcm9
minichromosome maintenance 9 homologous recombination repair factor
increases expression
ISO
nickel sulfate results in increased expression of MCM9 mRNA
CTD
PMID:22714537
NCBI chr20:32,818,219...32,929,577
Ensembl chr20:32,844,951...32,929,600
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Mcoln2
mucolipin TRP cation channel 2
increases expression
ISO
nickel sulfate results in increased expression of MCOLN2 mRNA
CTD
PMID:22714537
NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702
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Mcoln3
mucolipin TRP cation channel 3
increases expression
ISO
nickel sulfate results in increased expression of MCOLN3 mRNA
CTD
PMID:22714537
NCBI chr 2:235,008,716...235,042,885
Ensembl chr 2:234,966,010...235,043,047
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Mctp2
multiple C2 and transmembrane domain containing 2
increases expression
ISO
nickel sulfate results in increased expression of MCTP2 mRNA
CTD
PMID:22714537
NCBI chr 1:125,769,932...126,002,886
Ensembl chr 1:125,771,233...126,002,928
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Mdc1
mediator of DNA damage checkpoint 1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MDC1 mRNA
CTD
PMID:31734292
NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
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Mdfi
MyoD family inhibitor
increases expression
ISO
nickel sulfate results in increased expression of MDFI mRNA
CTD
PMID:16780908
NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217
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Mdfic
MyoD family inhibitor domain containing
decreases expression
ISO
nickel sulfate results in decreased expression of MDFIC mRNA
CTD
PMID:22714537
NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161
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Mdk
midkine
decreases expression
ISO
nickel sulfate results in decreased expression of MDK mRNA
CTD
PMID:22714537
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
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Me1
malic enzyme 1
increases expression
ISO
nickel sulfate results in increased expression of ME1 mRNA
CTD
PMID:16314067 PMID:20566472
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Med10
mediator complex subunit 10
increases expression
ISO
nickel sulfate results in increased expression of MED10 mRNA
CTD
PMID:22714537
NCBI chr 1:33,470,064...33,481,698
Ensembl chr 1:33,470,066...33,475,767
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Med12l
mediator complex subunit 12L
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MED12L mRNA
CTD
PMID:31734292
NCBI chr 2:143,253,048...143,576,507
Ensembl chr 2:143,252,139...143,573,741
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Med22
mediator complex subunit 22
increases expression
ISO
nickel sulfate results in increased expression of MED22 mRNA
CTD
PMID:16780908
NCBI chr 3:10,233,754...10,238,836
Ensembl chr 3:10,233,754...10,238,836
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Med4
mediator complex subunit 4
decreases expression
ISO
nickel sulfate results in decreased expression of MED4 mRNA
CTD
PMID:22714537
NCBI chr15:48,696,542...48,706,818
Ensembl chr15:48,696,511...48,706,820
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Medag
mesenteric estrogen-dependent adipogenesis
decreases expression
ISO
nickel sulfate results in decreased expression of MEDAG mRNA
CTD
PMID:22714537
NCBI chr12:5,613,191...5,634,583
Ensembl chr12:5,613,208...5,634,767
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Mef2c
myocyte enhancer factor 2C
decreases expression
ISO
nickel sulfate results in decreased expression of MEF2C mRNA
CTD
PMID:16166746
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Meis2
Meis homeobox 2
increases expression
ISO
nickel sulfate results in increased expression of MEIS2 mRNA
CTD
PMID:22714537
NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696
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Meltf
melanotransferrin
decreases expression
ISO
nickel sulfate results in decreased expression of MELTF mRNA
CTD
PMID:22714537
NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
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Mest
mesoderm specific transcript
decreases expression
ISO
nickel sulfate results in decreased expression of MEST mRNA
CTD
PMID:16166746
NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
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Mfsd9
major facilitator superfamily domain containing 9
increases expression
ISO
nickel sulfate results in increased expression of MFSD9 mRNA
CTD
PMID:16780908
NCBI chr 9:43,019,611...43,039,100
Ensembl chr 9:43,019,618...43,039,176
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Mgarp
mitochondria-localized glutamic acid-rich protein
increases expression
ISO
nickel sulfate results in increased expression of MGARP mRNA
CTD
PMID:22714537
NCBI chr 2:135,431,283...135,439,425
Ensembl chr 2:135,431,283...135,439,612
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Mgll
monoglyceride lipase
increases expression
ISO
nickel sulfate results in increased expression of MGLL mRNA
CTD
PMID:16780908
NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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Mgme1
mitochondrial genome maintenance exonuclease 1
decreases expression
ISO
nickel sulfate results in decreased expression of MGME1 mRNA
CTD
PMID:22714537
NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932
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Mgst1
microsomal glutathione S-transferase 1
increases expression
ISO
nickel sulfate results in increased expression of MGST1 mRNA
CTD
PMID:20566472 PMID:22714537
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
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Mid1
midline 1
decreases expression
ISO
nickel sulfate results in decreased expression of MID1 mRNA
CTD
PMID:22714537
NCBI chr X:24,116,674...24,491,205
Ensembl chr X:24,120,293...24,248,353
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Mif
macrophage migration inhibitory factor
increases expression
ISO
nickel sulfate results in increased expression of MIF mRNA
CTD
PMID:11751209
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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Mif4gd
MIF4G domain containing
increases expression
ISO
nickel sulfate results in increased expression of MIF4GD mRNA
CTD
PMID:22714537
NCBI chr10:100,847,168...100,852,166
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Mir125b1
microRNA 125b-1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR125B1 mRNA
CTD
PMID:31734292
NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
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Mir130b
microRNA 130b
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR130B mRNA
CTD
PMID:31734292
NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244
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Mir132
microRNA 132
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR132 mRNA
CTD
PMID:31734292
NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796
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Mir133b
microRNA 133b
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR133B mRNA
CTD
PMID:31734292
NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217
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Mir139
microRNA 139
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR139 mRNA
CTD
PMID:31734292
NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902
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Mir147
microRNA 147
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR147 mRNA
CTD
PMID:31734292
NCBI chr 3:109,722,692...109,722,770
Ensembl chr 3:109,722,692...109,722,770
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Mir154
microRNA 154
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR154 mRNA
CTD
PMID:31734292
NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
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Mir155hg
Mir155 host gene
decreases expression
ISO
nickel sulfate results in decreased expression of MIR155HG mRNA
CTD
PMID:22714537
NCBI chr11:23,773,468...23,775,697
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Mir181b1
microRNA 181b-1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR181B1 mRNA
CTD
PMID:31734292
NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797
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Mir21
microRNA 21
increases expression
ISO
nickel sulfate results in increased expression of MIR21 mRNA
CTD
PMID:22714537
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir210
microRNA 210
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR210 mRNA
CTD
PMID:31734292
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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Mir212
microRNA 212
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR212 mRNA
CTD
PMID:31734292
NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
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Mir23b
microRNA 23b
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR23B mRNA
CTD
PMID:31734292
NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
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Mir27a
microRNA 27a
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR27A mRNA
CTD
PMID:31734292
NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
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Mir3120
microRNA 3120
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR3120 mRNA; [nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR3120 mRNA
CTD
PMID:31734292
NCBI chr13:74,588,376...74,588,492
Ensembl chr13:74,588,372...74,588,481
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Mir32
microRNA 32
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR32 mRNA
CTD
PMID:31734292
NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152
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Mir320a
microRNA 320a
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR320A mRNA
CTD
PMID:31734292
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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Mir322
microRNA 322
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR322 mRNA
CTD
PMID:31734292
NCBI chr X:132,806,594...132,806,688
Ensembl chr X:132,806,594...132,806,688
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Mir503
microRNA 503
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR503 mRNA
CTD
PMID:31734292
NCBI chr X:132,806,303...132,806,373
Ensembl chr X:132,806,303...132,806,373
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Mir708
microRNA 708
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of MIR708 mRNA
CTD
PMID:31734292
NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963
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Mir760
microRNA 760
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIR760 mRNA
CTD
PMID:31734292
NCBI chr 2:210,392,616...210,392,695
Ensembl chr 2:210,392,616...210,392,695
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Mirlet7c1
microRNA let-7c-1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of MIRLET7C1 mRNA
CTD
PMID:31734292
NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
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Mitf
melanocyte inducing transcription factor
increases expression
ISO
nickel sulfate results in increased expression of MITF mRNA
CTD
PMID:16780908
NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
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Mki67
marker of proliferation Ki-67
increases expression
ISO
nickel sulfate results in increased expression of MKI67 protein
CTD
PMID:21776270
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mkks
MKKS centrosomal shuttling protein
decreases expression
ISO
nickel sulfate results in decreased expression of MKKS mRNA
CTD
PMID:22714537
NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162
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Mkx
mohawk homeobox
increases expression
ISO
nickel sulfate results in increased expression of MKX mRNA
CTD
PMID:22714537
NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124
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Mlf1
myeloid leukemia factor 1
decreases expression
ISO
nickel sulfate results in decreased expression of MLF1 mRNA
CTD
PMID:22714537
NCBI chr 2:151,648,492...151,681,654
Ensembl chr 2:151,648,511...151,681,652
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Mllt11
MLLT11, transcription factor 7 cofactor
decreases expression
ISO
nickel sulfate results in decreased expression of MLLT11 mRNA
CTD
PMID:22714537
NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
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Mllt3
MLLT3, super elongation complex subunit
decreases expression
ISO
nickel sulfate results in decreased expression of MLLT3 mRNA
CTD
PMID:22714537
NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361
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Mmp1
matrix metallopeptidase 1
increases expression
ISO
nickel sulfate results in increased expression of MMP1 mRNA
CTD
PMID:16780908
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp10
matrix metallopeptidase 10
increases expression
ISO
nickel sulfate results in increased expression of MMP10 mRNA
CTD
PMID:16780908
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
nickel sulfate results in increased expression of MMP12 mRNA
CTD
PMID:16166746
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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Mmp14
matrix metallopeptidase 14
increases expression
ISO
nickel sulfate results in increased expression of MMP14 mRNA
CTD
PMID:16100012
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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Mmp15
matrix metallopeptidase 15
decreases expression
ISO
nickel sulfate results in decreased expression of MMP15 mRNA
CTD
PMID:16166746
NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
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Mmp16
matrix metallopeptidase 16
decreases expression
ISO
nickel sulfate results in decreased expression of MMP16 mRNA
CTD
PMID:22714537
NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
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Mmp2
matrix metallopeptidase 2
increases secretion increases expression
ISO
nickel sulfate results in increased secretion of MMP2 protein nickel sulfate results in increased expression of MMP2 mRNA
CTD
PMID:15020194 PMID:18409814
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp24
matrix metallopeptidase 24
decreases expression
ISO
nickel sulfate results in decreased expression of MMP24 mRNA
CTD
PMID:22714537
NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
nickel sulfate results in increased expression of MMP3 mRNA
CTD
PMID:16166746 PMID:16780908
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp9
matrix metallopeptidase 9
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of MMP9 mRNA nickel sulfate results in increased expression of and results in increased secretion of MMP9 protein
CTD
PMID:15020194 PMID:18651567
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mns1
meiosis-specific nuclear structural 1
increases expression
ISO
nickel sulfate results in increased expression of MNS1 mRNA
CTD
PMID:22714537
NCBI chr 8:73,148,877...73,169,570
Ensembl chr 8:73,148,877...73,176,925
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Moxd1
monooxygenase, DBH-like 1
increases expression
ISO
nickel sulfate results in increased expression of MOXD1 mRNA
CTD
PMID:22714537
NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779
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Mphosph6
M phase phosphoprotein 6
increases expression
ISO
nickel sulfate results in increased expression of MPHOSPH6 mRNA
CTD
PMID:22714537
NCBI chr19:45,860,152...45,870,117
Ensembl chr19:45,860,154...45,870,170
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Mpo
myeloperoxidase
decreases expression
ISO
nickel sulfate results in decreased expression of MPO mRNA
CTD
PMID:17374397
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mpv17l
MPV17 mitochondrial inner membrane protein like
decreases expression
ISO
nickel sulfate results in decreased expression of MPV17L mRNA
CTD
PMID:22714537
NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649
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Mpzl1
myelin protein zero-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of MPZL1 mRNA
CTD
PMID:16780908
NCBI chr13:77,852,467...77,889,305
Ensembl chr13:77,852,467...77,896,616
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Mri1
methylthioribose-1-phosphate isomerase 1
increases expression
ISO
nickel sulfate results in increased expression of MRI1 mRNA
CTD
PMID:22714537
NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
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Mrpl1
mitochondrial ribosomal protein L1
decreases expression
ISO
nickel sulfate results in decreased expression of MRPL1 mRNA
CTD
PMID:22714537
NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721
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Mrpl12
mitochondrial ribosomal protein L12
increases expression
ISO
nickel sulfate results in increased expression of MRPL12 mRNA
CTD
PMID:18651567
NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
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Mrpl28
mitochondrial ribosomal protein L28
increases expression
ISO
nickel sulfate results in increased expression of MRPL28 mRNA
CTD
PMID:18651567
NCBI chr10:15,148,698...15,151,581
Ensembl chr10:15,148,681...15,151,581
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Mrpl35
mitochondrial ribosomal protein L35
decreases expression
ISO
nickel sulfate results in decreased expression of MRPL35 mRNA
CTD
PMID:17374397
NCBI chr 4:103,865,812...103,876,687
Ensembl chr 4:103,865,812...103,880,887
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Mrps18b
mitochondrial ribosomal protein S18B
increases expression
ISO
nickel sulfate results in increased expression of MRPS18B mRNA
CTD
PMID:22714537
NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260
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Mrps6
mitochondrial ribosomal protein S6
decreases expression
ISO
nickel sulfate results in decreased expression of MRPS6 mRNA
CTD
PMID:17374397
NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
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Ms4a6a
membrane spanning 4-domains A6A
decreases expression
ISO
nickel sulfate results in decreased expression of MS4A6A mRNA
CTD
PMID:16780908
NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
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Ms4a7
membrane spanning 4-domains A7
increases expression
ISO
nickel sulfate results in increased expression of MS4A7 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260
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Msc
musculin
increases expression
ISO
nickel sulfate results in increased expression of MSC mRNA
CTD
PMID:22714537
NCBI chr 5:4,547,335...4,553,206
Ensembl chr 5:4,547,405...4,553,203
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Msln
mesothelin
decreases expression
ISO
nickel sulfate results in decreased expression of MSLN mRNA
CTD
PMID:22714537
NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
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Msmb
microseminoprotein, beta
decreases expression
ISO
nickel sulfate results in decreased expression of MSMB mRNA
CTD
PMID:18651567
NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
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Mst1r
macrophage stimulating 1 receptor
decreases expression affects response to substance multiple interactions increases expression
ISO
nickel sulfate results in decreased expression of MST1R mRNA MST1R protein affects the susceptibility to nickel sulfate MST1R protein affects the reaction [nickel sulfate results in increased abundance of Nitrites] nickel sulfate results in increased expression of MST1R mRNA
CTD
PMID:11751209 PMID:16166746 PMID:16780908
NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455
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Mt1
metallothionein 1
increases expression affects expression
EXP ISO
nickel sulfate results in increased expression of MT1A mRNA nickel sulfate affects the expression of MT1 mRNA
CTD
PMID:12718980 PMID:19679144
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A
metallothionein 2A
increases expression
ISO
nickel sulfate results in increased expression of MT2A mRNA nickel sulfate results in increased expression of MT2 mRNA
CTD
PMID:16100012 PMID:16314067 PMID:19131640 PMID:20491607
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mtarc2
mitochondrial amidoxime reducing component 2
increases expression
ISO
nickel sulfate results in increased expression of MTARC2 mRNA
CTD
PMID:22714537
NCBI chr13:96,362,810...96,397,284
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Mtf1
metal-regulatory transcription factor 1
increases activity affects phosphorylation
ISO
nickel sulfate results in increased activity of MTF1 protein nickel sulfate affects the phosphorylation of MTF1 protein
CTD
PMID:19131640 PMID:24962574
NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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Mtf2
metal response element binding transcription factor 2
affects expression
ISO
nickel sulfate affects the expression of MTF2 mRNA
CTD
PMID:12718980
NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
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Mtmr1
myotubularin related protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of MTMR1 mRNA
CTD
PMID:22714537
NCBI chr18:215,031...248,541
Ensembl chr18:215,089...248,541
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Mtss1
MTSS I-BAR domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of MTSS1 mRNA
CTD
PMID:16780908 PMID:17382205
NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
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Mtus1
microtubule associated scaffold protein 1
increases expression
ISO
nickel sulfate results in increased expression of MTUS1 mRNA
CTD
PMID:22714537
NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793
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Muc1
mucin 1, cell surface associated
decreases expression
ISO
nickel sulfate results in decreased expression of MUC1 mRNA
CTD
PMID:22714537
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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Mvd
mevalonate diphosphate decarboxylase
increases expression
ISO
nickel sulfate results in increased expression of MVD mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Mx1
MX dynamin like GTPase 1
increases expression
ISO
nickel sulfate results in increased expression of MX1 mRNA
CTD
PMID:25673294
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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Myadm
myeloid-associated differentiation marker
decreases expression
ISO
nickel sulfate results in decreased expression of MYADM mRNA
CTD
PMID:22714537
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression increases expression increases phosphorylation increases ubiquitination increases degradation multiple interactions
ISO EXP
nickel sulfate results in decreased expression of MYC mRNA; nickel sulfate results in decreased expression of MYC protein nickel sulfate results in increased expression of MYC mRNA; nickel sulfate results in increased expression of MYC protein nickel sulfate results in increased phosphorylation of MYC protein nickel sulfate results in increased ubiquitination of MYC protein nickel sulfate results in increased degradation of MYC protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nickel sulfate results in increased expression of MYC protein]; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in increased degradation of MYC protein]; FBXW7 mRNA affects the reaction [nickel sulfate results in increased degradation of MYC protein]; FBXW7 protein affects the reaction [nickel sulfate results in increased degradation of MYC protein]; U 0126 inhibits the reaction [nickel sulfate results in increased expression of MYC protein]; USP28 protein inhibits the reaction [nickel sulfate results in increased degradation of MYC protein]
CTD
PMID:16166746 PMID:17374397 PMID:19135467 PMID:20046830 PMID:23568779
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Mycl
MYCL proto-oncogene, bHLH transcription factor
decreases expression
ISO
nickel sulfate results in decreased expression of MYCL mRNA
CTD
PMID:16780908
NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
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Myh1
myosin heavy chain 1
increases expression
ISO
nickel sulfate results in increased expression of MYH1 mRNA
CTD
PMID:16166746
NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295
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Myh10
myosin heavy chain 10
decreases expression
ISO
nickel sulfate results in decreased expression of MYH10 mRNA
CTD
PMID:16780908
NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165
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Myl1
myosin, light chain 1
increases expression
ISO
nickel sulfate results in increased expression of MYL1 mRNA
CTD
PMID:16166746
NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
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Myl11
myosin light chain 11
increases expression
ISO
nickel sulfate results in increased expression of MYLPF mRNA
CTD
PMID:16166746
NCBI chr 1:181,829,703...181,832,546
Ensembl chr 1:181,829,743...181,832,545
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Myl2
myosin light chain 2
increases expression
ISO
nickel sulfate results in increased expression of MYL2 mRNA
CTD
PMID:16166746
NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
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Mylip
myosin regulatory light chain interacting protein
increases expression
ISO
nickel sulfate results in increased expression of MYLIP mRNA
CTD
PMID:22714537
NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
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Myo10
myosin X
increases expression
ISO
nickel sulfate results in increased expression of MYO10 mRNA
CTD
PMID:22714537
NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030
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Myo18a
myosin XVIIIa
increases expression
ISO
nickel sulfate results in increased expression of MYO18A mRNA
CTD
PMID:18651567
NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468
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Myo1e
myosin IE
increases expression
ISO
nickel sulfate results in increased expression of MYO1E mRNA
CTD
PMID:16780908
NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
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Myo5c
myosin VC
decreases expression
ISO
nickel sulfate results in decreased expression of MYO5C mRNA
CTD
PMID:22714537
NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
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Myocd
myocardin
increases expression
ISO
nickel sulfate results in increased expression of MYOCD mRNA
CTD
PMID:22714537
NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
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Myof
myoferlin
increases expression
ISO
nickel sulfate results in increased expression of MYOF mRNA
CTD
PMID:16780908
NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334
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Mypn
myopalladin
increases expression
ISO
nickel sulfate results in increased expression of MYPN mRNA
CTD
PMID:22714537
NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443
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Naaa
N-acylethanolamine acid amidase
decreases expression
ISO
nickel sulfate results in decreased expression of NAAA mRNA
CTD
PMID:16780908
NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410
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Nampt
nicotinamide phosphoribosyltransferase
increases expression
ISO
nickel sulfate results in increased expression of NAMPT mRNA
CTD
PMID:17374397
NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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Nanp
N-acetylneuraminic acid phosphatase
decreases expression
ISO
nickel sulfate results in decreased expression of NANP mRNA
CTD
PMID:22714537
NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648
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Napb
NSF attachment protein beta
decreases expression
ISO
nickel sulfate results in decreased expression of NAPB mRNA
CTD
PMID:22714537
NCBI chr 3:136,132,248...136,179,280
Ensembl chr 3:136,133,428...136,179,345
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Napsa
napsin A aspartic peptidase
decreases expression
ISO
nickel sulfate results in decreased expression of NAPSA mRNA
CTD
PMID:16100012
NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094
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Nav3
neuron navigator 3
increases expression
ISO
nickel sulfate results in increased expression of NAV3 mRNA
CTD
PMID:17382205 PMID:22714537
NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
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Ncf2
neutrophil cytosolic factor 2
decreases expression
ISO
nickel sulfate results in decreased expression of NCF2 mRNA
CTD
PMID:22714537
NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ncoa4
nuclear receptor coactivator 4
decreases expression
ISO
nickel sulfate results in decreased expression of NCOA4 mRNA
CTD
PMID:16780908
NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641 Ensembl chr16:7,366,542...7,409,641
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Ncoa7
nuclear receptor coactivator 7
increases expression
ISO
nickel sulfate results in increased expression of NCOA7 mRNA
CTD
PMID:22714537
NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
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Ndrg1
N-myc downstream regulated 1
affects expression multiple interactions increases expression
ISO
nickel sulfate affects the expression of NDRG1 mRNA Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of NDRG1 protein] nickel sulfate results in increased expression of NDRG1 mRNA; nickel sulfate results in increased expression of NDRG1 protein
CTD
PMID:12718980 PMID:16288478 PMID:17382205
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Ndrg2
NDRG family member 2
increases expression
ISO
nickel sulfate results in increased expression of NDRG2 mRNA
CTD
PMID:22714537
NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
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Ndufaf5
NADH:ubiquinone oxidoreductase complex assembly factor 5
decreases expression
ISO
nickel sulfate results in decreased expression of NDUFAF5 mRNA
CTD
PMID:22714537
NCBI chr 3:127,507,931...127,537,477
Ensembl chr 3:127,507,941...127,537,477
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
increases expression
ISO
nickel sulfate results in increased expression of NEDD9 mRNA
CTD
PMID:22714537
NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
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Negr1
neuronal growth regulator 1
decreases expression
ISO
nickel sulfate results in decreased expression of NEGR1 mRNA
CTD
PMID:22714537
NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730
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Net1
neuroepithelial cell transforming 1
increases expression
ISO
nickel sulfate results in increased expression of NET1 mRNA
CTD
PMID:16780908
NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441
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Neu1
neuraminidase 1
increases expression
ISO
nickel sulfate results in increased expression of NEU1 mRNA
CTD
PMID:22714537
NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745
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Nexn
nexilin (F actin binding protein)
decreases expression
ISO
nickel sulfate results in decreased expression of NEXN mRNA
CTD
PMID:22714537
NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342
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Nfasc
neurofascin
decreases expression
ISO
nickel sulfate results in decreased expression of NFASC mRNA
CTD
PMID:22714537
NCBI chr13:43,997,223...44,183,863
Ensembl chr13:43,997,224...44,183,880
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression multiple interactions increases methylation
ISO
nickel sulfate results in increased expression of NFE2L2 protein Quercetin inhibits the reaction [nickel sulfate results in increased methylation of NFE2L2 promoter]
CTD
PMID:19033392 PMID:25957741
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfib
nuclear factor I/B
decreases expression
ISO
nickel sulfate results in decreased expression of NFIB mRNA
CTD
PMID:22714537
NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479
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Nfil3
nuclear factor, interleukin 3 regulated
increases expression
ISO
nickel sulfate results in increased expression of NFIL3 mRNA
CTD
PMID:16780908 PMID:18651567
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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Nfkb1
nuclear factor kappa B subunit 1
increases expression affects expression
ISO
nickel sulfate results in increased expression of NFKB1 mRNA nickel sulfate affects the expression of NFKB1 mRNA
CTD
PMID:16780908 PMID:20385217
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkbia
NFKB inhibitor alpha
increases degradation increases expression multiple interactions
ISO
nickel sulfate results in increased degradation of NFKBIA protein nickel sulfate results in increased expression of NFKBIA mRNA [nickel sulfate results in increased degradation of NFKBIA protein] which results in increased activity of RELA protein; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased degradation of NFKBIA protein]
CTD
PMID:16780908 PMID:17636246 PMID:19101624 PMID:22714537
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nid1
nidogen 1
decreases expression
ISO
nickel sulfate results in decreased expression of NID1 mRNA
CTD
PMID:16166746
NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
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Ninj1
ninjurin 1
increases expression
ISO
nickel sulfate results in increased expression of NINJ1 mRNA
CTD
PMID:16314067 PMID:16780908 PMID:17374397 PMID:22714537
NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
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Ninl
ninein-like
decreases expression
ISO
nickel sulfate results in decreased expression of NINL mRNA
CTD
PMID:22714537
NCBI chr 3:139,748,353...139,814,683
Ensembl chr 3:139,748,355...139,814,622
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Nlrp10
NLR family, pyrin domain containing 10
decreases expression
ISO
nickel sulfate results in decreased expression of NLRP10 mRNA
CTD
PMID:22714537
NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363
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Nmt2
N-myristoyltransferase 2
decreases expression
ISO
nickel sulfate results in decreased expression of NMT2 mRNA
CTD
PMID:22714537
NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080
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Nmu
neuromedin U
decreases expression
ISO
nickel sulfate results in decreased expression of NMU mRNA
CTD
PMID:22714537
NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
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Noc3l
NOC3-like DNA replication regulator
decreases expression
ISO
nickel sulfate results in decreased expression of NOC3L mRNA
CTD
PMID:22714537
NCBI chr 1:236,556,037...236,585,372
Ensembl chr 1:236,556,789...236,585,318
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Nol4l
nucleolar protein 4-like
increases expression
ISO
nickel sulfate results in increased expression of NOL4L mRNA
CTD
PMID:22714537
NCBI chr 3:141,884,840...142,007,668
Ensembl chr 3:141,884,840...142,008,976
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Nop56
NOP56 ribonucleoprotein
decreases expression
ISO
nickel sulfate results in decreased expression of NOP56 mRNA
CTD
PMID:22714537
NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
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Nos2
nitric oxide synthase 2
increases expression multiple interactions increases activity
EXP ISO
nickel sulfate results in increased expression of NOS2 mRNA nickel sulfate promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; nickel sulfate promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [nickel sulfate results in increased expression of NOS2 protein] nickel sulfate results in increased activity of NOS2 protein Ascorbic Acid inhibits the reaction [nickel sulfate results in increased activity of NOS2 protein]
CTD
PMID:11114790 PMID:23415871 PMID:23463385 PMID:25957741
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nova1
NOVA alternative splicing regulator 1
decreases expression
ISO
nickel sulfate results in decreased expression of NOVA1 mRNA
CTD
PMID:22714537
NCBI chr 6:63,780,105...63,905,567
Ensembl chr 6:63,783,489...63,906,289
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Npas2
neuronal PAS domain protein 2
increases expression
ISO
nickel sulfate results in increased expression of NPAS2 mRNA
CTD
PMID:17382205 PMID:22714537
NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
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Npl
N-acetylneuraminate pyruvate lyase
decreases expression
ISO
nickel sulfate results in decreased expression of NPL mRNA
CTD
PMID:16780908
NCBI chr13:65,655,099...65,697,464
Ensembl chr13:65,655,118...65,697,372
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Nppb
natriuretic peptide B
decreases expression
ISO
nickel sulfate results in decreased expression of NPPB mRNA
CTD
PMID:22714537
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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Npr2
natriuretic peptide receptor 2
increases expression
ISO
nickel sulfate results in increased expression of NPR2 mRNA
CTD
PMID:22714537
NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
nickel sulfate results in increased expression of NQO1 mRNA
CTD
PMID:16314067 PMID:19033392 PMID:20566472 PMID:22714537
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nqo2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
increases expression
ISO
nickel sulfate results in increased expression of NQO2 mRNA
CTD
PMID:22714537
NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
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Nr1h3
nuclear receptor subfamily 1, group H, member 3
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of NR1H3 mRNA
CTD
PMID:31734292
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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Nr2f6
nuclear receptor subfamily 2, group F, member 6
increases expression
ISO
nickel sulfate results in increased expression of NR2F6 mRNA
CTD
PMID:16780908
NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases expression
ISO
nickel sulfate results in increased expression of NR3C1 mRNA
CTD
PMID:17374397
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
nickel sulfate results in increased expression of NR4A1 mRNA
CTD
PMID:16780908
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
ISO
nickel sulfate results in increased expression of NR4A2 mRNA
CTD
PMID:16780908
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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Nrep
neuronal regeneration related protein
decreases expression
ISO
nickel sulfate results in decreased expression of NREP mRNA
CTD
PMID:16780908 PMID:17374397 PMID:22714537
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nrg1
neuregulin 1
decreases expression
ISO
nickel sulfate results in decreased expression of NRG1 mRNA
CTD
PMID:22714537
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Nrp2
neuropilin 2
increases expression decreases expression
ISO
nickel sulfate results in increased expression of NRP2 mRNA nickel sulfate results in decreased expression of NRP2 mRNA
CTD
PMID:16780908 PMID:18832182
NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
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Nrsn2
neurensin 2
decreases expression
ISO
nickel sulfate results in decreased expression of NRSN2 mRNA
CTD
PMID:22714537
NCBI chr 3:140,838,813...140,847,291
Ensembl chr 3:140,838,814...140,847,297
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Nsfl1c
NSFL1 cofactor
decreases expression
ISO
nickel sulfate results in decreased expression of NSFL1C mRNA
CTD
PMID:22714537
NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870
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Nt5c3a
5'-nucleotidase, cytosolic IIIA
decreases expression
ISO
nickel sulfate results in decreased expression of NT5C3A mRNA
CTD
PMID:16780908
NCBI chr 4:86,161,642...86,204,656
Ensembl chr 4:86,161,643...86,204,628
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Ntaq1
N-terminal glutamine amidase 1
increases expression
ISO
nickel sulfate results in increased expression of NTAQ1 mRNA
CTD
PMID:22714537
NCBI chr 7:89,684,318...89,704,484
Ensembl chr 7:89,684,323...89,704,474
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Nub1
negative regulator of ubiquitin-like proteins 1
increases expression
ISO
nickel sulfate results in increased expression of NUB1 mRNA
CTD
PMID:16780908
NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694
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Nucb1
nucleobindin 1
decreases expression
ISO
nickel sulfate results in decreased expression of NUCB1 mRNA
CTD
PMID:16100012
NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
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Nudt14
nudix hydrolase 14
increases expression
ISO
nickel sulfate results in increased expression of NUDT14 mRNA
CTD
PMID:22714537
NCBI chr 6:132,010,309...132,017,298
Ensembl chr 6:132,010,297...132,017,298
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Nudt7
nudix hydrolase 7
increases expression
ISO
nickel sulfate results in increased expression of NUDT7 mRNA
CTD
PMID:22714537
NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081
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Nup210
nucleoporin 210
decreases expression
ISO
nickel sulfate results in decreased expression of NUP210 mRNA
CTD
PMID:22714537
NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874
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Nup214
nucleoporin 214
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of NUP214 mRNA
CTD
PMID:31734292
NCBI chr 3:15,255,111...15,340,568
Ensembl chr 3:15,255,119...15,340,568
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Nup88
nucleoporin 88
increases expression
ISO
nickel sulfate results in increased expression of NUP88 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
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Nup98
nucleoporin 98 and 96 precursor
increases expression
ISO
nickel sulfate results in increased expression of NUP98 mRNA
CTD
PMID:18651567
NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415
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Oas3
2'-5'-oligoadenylate synthetase 3
increases expression
ISO
nickel sulfate results in increased expression of OAS3 mRNA
CTD
PMID:22714537
NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
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Oasl
2'-5'-oligoadenylate synthetase-like
increases expression
ISO
nickel sulfate results in increased expression of OASL mRNA
CTD
PMID:22714537
NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
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Odc1
ornithine decarboxylase 1
increases expression
ISO
nickel sulfate results in increased expression of ODC1 mRNA
CTD
PMID:18651567
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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Ogdh
oxoglutarate dehydrogenase
increases expression
ISO
nickel sulfate results in increased expression of OGDH mRNA
CTD
PMID:18651567
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
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Olfml2b
olfactomedin-like 2B
increases expression
ISO
nickel sulfate results in increased expression of OLFML2B mRNA
CTD
PMID:22714537
NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
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Osbpl5
oxysterol binding protein-like 5
increases expression
ISO
nickel sulfate results in increased expression of OSBPL5 mRNA
CTD
PMID:22714537
NCBI chr 1:198,862,071...198,916,469
Ensembl chr 1:198,862,055...198,916,469
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Osmr
oncostatin M receptor
increases expression
ISO
nickel sulfate results in increased expression of OSMR mRNA
CTD
PMID:16166746
NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
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Ostf1
osteoclast stimulating factor 1
increases expression
ISO
nickel sulfate results in increased expression of OSTF1 mRNA
CTD
PMID:16780908
NCBI chr 1:216,002,037...216,049,226
Ensembl chr 1:216,002,044...216,049,221
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Otud1
OTU deubiquitinase 1
increases expression
ISO
nickel sulfate results in increased expression of OTUD1 mRNA
CTD
PMID:17374397
NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
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Oxct1
3-oxoacid CoA transferase 1
decreases expression
ISO
nickel sulfate results in decreased expression of OXCT1 mRNA
CTD
PMID:16780908
NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
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P4ha2
prolyl 4-hydroxylase subunit alpha 2
increases expression
ISO
nickel sulfate results in increased expression of P4HA2 mRNA
CTD
PMID:17382205
NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314
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Pabir3
PABIR family member 3
increases expression
ISO
nickel sulfate results in increased expression of PABIR3 mRNA
CTD
PMID:22714537
NCBI chr X:133,020,162...133,083,801
Ensembl chr X:133,020,190...133,083,805
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Palld
palladin, cytoskeletal associated protein
decreases expression
ISO
nickel sulfate results in decreased expression of PALLD mRNA
CTD
PMID:22714537
NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
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Pam
peptidylglycine alpha-amidating monooxygenase
decreases expression
ISO
nickel sulfate results in decreased expression of PAM mRNA
CTD
PMID:22714537
NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
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Pamr1
peptidase domain containing associated with muscle regeneration 1
decreases expression
ISO
nickel sulfate results in decreased expression of PAMR1 mRNA
CTD
PMID:22714537
NCBI chr 3:88,889,061...88,988,615
Ensembl chr 3:88,889,046...88,988,606
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Paqr5
progestin and adipoQ receptor family member 5
decreases expression
ISO
nickel sulfate results in decreased expression of PAQR5 mRNA
CTD
PMID:22714537
NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage multiple interactions
ISO EXP
nickel sulfate results in increased cleavage of PARP1 protein 3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]]; nickel sulfate inhibits the reaction [Potassium Dichromate results in increased cleavage of and results in increased activity of PARP1 protein]; nickel sulfate results in increased cleavage of and results in increased activity of PARP1 protein; PARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]; Potassium Dichromate inhibits the reaction [nickel sulfate results in increased cleavage of and results in increased activity of PARP1 protein]
CTD
PMID:19135467 PMID:20493934
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pbx1
PBX homeobox 1
increases expression
ISO
nickel sulfate results in increased expression of PBX1 mRNA
CTD
PMID:22714537
NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
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Pcdhb19
protocadherin beta 19
increases expression
ISO
nickel sulfate results in increased expression of PCDHB12 mRNA
CTD
PMID:22714537
NCBI chr18:29,204,838...29,207,646
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Pcgf5
polycomb group ring finger 5
decreases expression
ISO
nickel sulfate results in decreased expression of PCGF5 mRNA
CTD
PMID:22714537
NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
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Pcna
proliferating cell nuclear antigen
decreases expression
ISO
nickel sulfate results in decreased expression of PCNA mRNA
CTD
PMID:22714537
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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PCOLCE2
procollagen C-endopeptidase enhancer 2
decreases expression
ISO
nickel sulfate results in decreased expression of PCOLCE2 mRNA
CTD
PMID:16100012
NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
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Pcyt2
phosphate cytidylyltransferase 2, ethanolamine
increases expression
ISO
nickel sulfate results in increased expression of PCYT2 mRNA
CTD
PMID:22714537
NCBI chr10:105,888,769...105,896,182
Ensembl chr10:105,888,775...105,896,172
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Pde10a
phosphodiesterase 10A
increases expression
ISO
nickel sulfate results in increased expression of PDE10A mRNA
CTD
PMID:22714537
NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
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Pde3a
phosphodiesterase 3A
increases expression
ISO
nickel sulfate results in increased expression of PDE3A mRNA
CTD
PMID:17382205
NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274
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Pde4b
phosphodiesterase 4B
increases expression
ISO
nickel sulfate results in increased expression of PDE4B mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
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Pde4d
phosphodiesterase 4D
increases expression
ISO
nickel sulfate results in increased expression of PDE4D mRNA
CTD
PMID:17374397
NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
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Pde4dip
phosphodiesterase 4D interacting protein
decreases expression
ISO
nickel sulfate results in decreased expression of PDE4DIP mRNA
CTD
PMID:22714537
NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
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Pde9a
phosphodiesterase 9A
increases expression
ISO
nickel sulfate results in increased expression of PDE9A mRNA
CTD
PMID:22714537
NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948
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Pdgfa
platelet derived growth factor subunit A
increases expression
ISO
nickel sulfate results in increased expression of PDGFA mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdlim3
PDZ and LIM domain 3
increases expression
ISO
nickel sulfate results in increased expression of PDLIM3 mRNA
CTD
PMID:22714537
NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
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Pdpn
podoplanin
decreases expression
ISO
nickel sulfate results in decreased expression of PDPN mRNA
CTD
PMID:22714537
NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
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Pdzd2
PDZ domain containing 2
decreases expression
ISO
nickel sulfate results in decreased expression of PDZD2 mRNA
CTD
PMID:22714537
NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524
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Pdzk1
PDZ domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of PDZK1 mRNA
CTD
PMID:22714537
NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
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Peg10
paternally expressed 10
increases expression
ISO
nickel sulfate results in increased expression of PEG10 mRNA
CTD
PMID:22714537
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
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Peli1
pellino E3 ubiquitin protein ligase 1
decreases expression
ISO
nickel sulfate results in decreased expression of PELI1 mRNA
CTD
PMID:22714537
NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285
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Pelo
pelota mRNA surveillance and ribosome rescue factor
decreases expression
ISO
nickel sulfate results in decreased expression of PELO mRNA
CTD
PMID:22714537
NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746
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Perp
p53 apoptosis effector related to PMP22
increases expression
ISO
nickel sulfate results in increased expression of PERP mRNA
CTD
PMID:22714537
NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
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Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
increases expression
ISO
nickel sulfate results in increased expression of PFKFB3 mRNA
CTD
PMID:17382205
NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
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Pgd
phosphogluconate dehydrogenase
increases expression
ISO
nickel sulfate results in increased expression of PGD mRNA
CTD
PMID:16314067 PMID:20566472
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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Pgf
placental growth factor
multiple interactions increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PGF mRNA nickel sulfate results in increased expression of PGF mRNA
CTD
PMID:18651567 PMID:18832182 PMID:22714537
NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
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Pgk1
phosphoglycerate kinase 1
increases expression affects expression
ISO
nickel sulfate results in increased expression of PGK1 mRNA nickel sulfate affects the expression of PGK1 mRNA
CTD
PMID:16100012 PMID:17382205 PMID:18202158
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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Pglyrp1
peptidoglycan recognition protein 1
increases expression
ISO
nickel sulfate results in increased expression of PGLYRP1 mRNA
CTD
PMID:16166746
NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001
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Pgm1
phosphoglucomutase 1
decreases expression
ISO
nickel sulfate results in decreased expression of PGM1 mRNA
CTD
PMID:22714537
NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
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Phf1
PHD finger protein 1
increases expression multiple interactions
ISO EXP
nickel sulfate results in increased expression of PHF1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of PHF1 mRNA
CTD
PMID:22714537 PMID:31734292
NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
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Phf12
PHD finger protein 12
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of PHF12 mRNA
CTD
PMID:31734292
NCBI chr10:62,871,309...62,919,026
Ensembl chr10:62,872,195...62,919,000
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Phka1
phosphorylase kinase regulatory subunit alpha 1
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of PHKA1 mRNA nickel sulfate results in increased expression of PHKA1 mRNA
CTD
PMID:16166746 PMID:22714537
NCBI chr X:67,601,302...67,738,504
Ensembl chr X:67,601,302...67,738,455
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Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
ISO
nickel sulfate results in increased expression of PHLDA1 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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Picalm
phosphatidylinositol binding clathrin assembly protein
increases expression
ISO
nickel sulfate results in increased expression of PICALM mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
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Piezo2
piezo-type mechanosensitive ion channel component 2
increases expression
ISO
nickel sulfate results in increased expression of PIEZO2 mRNA
CTD
PMID:22714537
NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216
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Pigm
phosphatidylinositol glycan anchor biosynthesis, class M
decreases expression
ISO
nickel sulfate results in decreased expression of PIGM mRNA
CTD
PMID:22714537
NCBI chr13:84,838,329...84,842,026
Ensembl chr13:84,838,175...84,843,381
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Pilra
paired immunoglobin-like type 2 receptor alpha
increases expression
ISO
nickel sulfate results in increased expression of PILRA mRNA
CTD
PMID:17382205
NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094
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Pim1
Pim-1 proto-oncogene, serine/threonine kinase
increases expression
ISO
nickel sulfate results in increased expression of PIM1 mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
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Pin1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
increases expression
ISO
nickel sulfate results in increased expression of PIN1 mRNA
CTD
PMID:18651567
NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
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Pir
pirin
increases expression
ISO
nickel sulfate results in increased expression of PIR mRNA
CTD
PMID:16314067 PMID:22714537
NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
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Pkp3
plakophilin 3
increases expression
ISO
nickel sulfate results in increased expression of PKP3 mRNA
CTD
PMID:18651567
NCBI chr 1:196,187,914...196,198,843
Ensembl chr 1:196,187,835...196,198,844
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Plaat3
phospholipase A and acyltransferase 3
increases expression
ISO
nickel sulfate results in increased expression of PLAAT3 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
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Plagl1
PLAG1 like zinc finger 1
decreases expression
ISO
nickel sulfate results in decreased expression of PLAGL1 mRNA
CTD
PMID:16166746 PMID:22714537
NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
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Plat
plasminogen activator, tissue type
increases expression
ISO
nickel sulfate results in increased expression of PLAT mRNA
CTD
PMID:16100012 PMID:16780908 PMID:17374397
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plau
plasminogen activator, urokinase
multiple interactions decreases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of PLAU mRNA nickel sulfate results in decreased expression of PLAU mRNA
CTD
PMID:18832182
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Plaur
plasminogen activator, urokinase receptor
decreases expression
ISO
nickel sulfate results in decreased expression of PLAUR mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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Plce1
phospholipase C, epsilon 1
decreases expression
ISO
nickel sulfate results in decreased expression of PLCE1 mRNA
CTD
PMID:22714537
NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
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Plcg2
phospholipase C, gamma 2
increases expression
ISO
nickel sulfate results in increased expression of PLCG2 mRNA
CTD
PMID:22714537
NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
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Plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of PLCXD1 mRNA
CTD
PMID:22714537
NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392
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Pld3
phospholipase D family, member 3
increases expression
ISO
nickel sulfate results in increased expression of PLD3 mRNA
CTD
PMID:18651567
NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072
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Plec
plectin
increases expression
ISO
nickel sulfate results in increased expression of PLEC mRNA
CTD
PMID:18651567
NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
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Plek
pleckstrin
increases expression
ISO
nickel sulfate results in increased expression of PLEK mRNA
CTD
PMID:16780908
NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
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Plekha1
pleckstrin homology domain containing A1
decreases expression
ISO
nickel sulfate results in decreased expression of PLEKHA1 mRNA
CTD
PMID:22714537
NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
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Plekha7
pleckstrin homology domain containing A7
decreases expression
ISO
nickel sulfate results in decreased expression of PLEKHA7 mRNA
CTD
PMID:22714537
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
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Plekhh2
pleckstrin homology, MyTH4 and FERM domain containing H2
increases expression
ISO
nickel sulfate results in increased expression of PLEKHH2 mRNA
CTD
PMID:22714537
NCBI chr 6:10,032,837...10,132,081
Ensembl chr 6:10,032,660...10,140,794
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Plin2
perilipin 2
increases expression
ISO
nickel sulfate results in increased expression of PLIN2 mRNA
CTD
PMID:16314067 PMID:18651567
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Plk2
polo-like kinase 2
decreases expression
ISO
nickel sulfate results in decreased expression of PLK2 mRNA
CTD
PMID:22714537
NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
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Plpp4
phospholipid phosphatase 4
decreases expression
ISO
nickel sulfate results in decreased expression of PLPP4 mRNA
CTD
PMID:22714537
NCBI chr 1:183,829,794...183,959,319
Ensembl chr 1:183,830,409...183,959,319
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Pls3
plastin 3
decreases expression
ISO
nickel sulfate results in decreased expression of PLS3 mRNA
CTD
PMID:18651567
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
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Plscr1
phospholipid scramblase 1
increases expression
ISO
nickel sulfate results in increased expression of PLSCR1 mRNA
CTD
PMID:22714537
NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
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Plscr4
phospholipid scramblase 4
increases expression
ISO
nickel sulfate results in increased expression of PLSCR4 mRNA
CTD
PMID:22714537
NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049
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Pltp
phospholipid transfer protein
decreases expression
ISO
nickel sulfate results in decreased expression of PLTP mRNA
CTD
PMID:16100012
NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
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Plxna2
plexin A2
decreases expression
ISO
nickel sulfate results in decreased expression of PLXNA2 mRNA
CTD
PMID:22714537
NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979
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Plxna3
plexin A3
decreases expression
ISO
nickel sulfate results in decreased expression of PLXNA3 mRNA
CTD
PMID:22714537
NCBI chr X:152,115,699...152,131,608
Ensembl chr X:152,115,819...152,131,603
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
nickel sulfate results in increased expression of PMAIP1 mRNA
CTD
PMID:16314067 PMID:16780908
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Pnkd
PNKD metallo-beta-lactamase domain containing
increases expression
ISO
nickel sulfate results in increased expression of PNKD mRNA
CTD
PMID:22714537
NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
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Pnpla4
patatin like phospholipase domain containing 4
decreases expression
ISO
nickel sulfate results in decreased expression of PNPLA4 mRNA
CTD
PMID:22714537
NCBI chr X:42,313,554...42,318,451
Ensembl chr X:42,305,373...42,318,552
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Poglut2
protein O-glucosyltransferase 2
decreases expression
ISO
nickel sulfate results in decreased expression of POGLUT2 mRNA
CTD
PMID:22714537
NCBI chr 9:46,256,388...46,268,714
Ensembl chr 9:46,256,390...46,268,532
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Polr1has
RNA polymerase I subunit H, antisense
increases expression
ISO
nickel sulfate results in increased expression of POLR1HASP mRNA
CTD
PMID:22714537
NCBI chr 9:16,098,624...16,099,790
Ensembl chr 9:16,098,624...16,099,790
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Polr2a
RNA polymerase II subunit A
increases expression
ISO
nickel sulfate results in increased expression of POLR2A mRNA
CTD
PMID:16780908
NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
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Polr3f
RNA polymerase III subunit F
decreases expression
ISO
nickel sulfate results in decreased expression of POLR3F mRNA
CTD
PMID:22714537
NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837
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Polr3g
RNA polymerase III subunit G
increases expression
ISO
nickel sulfate results in increased expression of POLR3G mRNA
CTD
PMID:22714537
NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125
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Porcn
porcupine O-acyltransferase
increases expression
ISO
nickel sulfate results in increased expression of PORCN mRNA
CTD
PMID:16780908
NCBI chr X:14,285,864...14,298,481
Ensembl chr X:14,285,871...14,298,481
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Postn
periostin
increases expression
ISO
nickel sulfate results in increased expression of POSTN mRNA
CTD
PMID:22714537
NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
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Pparg
peroxisome proliferator-activated receptor gamma
increases expression
ISO
nickel sulfate results in increased expression of PPARG mRNA
CTD
PMID:16314067
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargc1a
PPARG coactivator 1 alpha
multiple interactions decreases expression
ISO
[nickel sulfate co-treated with Particulate Matter] results in decreased expression of PPARGC1A mRNA nickel sulfate results in decreased expression of PPARGC1A mRNA
CTD
PMID:23126276
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Ppia
peptidylprolyl isomerase A
affects expression
ISO
nickel sulfate affects the expression of PPIA mRNA
CTD
PMID:18202158
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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Ppid
peptidylprolyl isomerase D
decreases expression
ISO
nickel sulfate results in decreased expression of PPID mRNA
CTD
PMID:16100012
NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221
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Ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
increases expression
ISO
nickel sulfate results in increased expression of PPM1H mRNA
CTD
PMID:22714537
NCBI chr 7:58,338,661...58,599,547
Ensembl chr 7:58,338,661...58,599,547
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
nickel sulfate results in increased expression of PPP1R15A mRNA
CTD
PMID:18651567
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Ppp2r1a
protein phosphatase 2 scaffold subunit A alpha
increases expression
ISO
nickel sulfate results in increased expression of PPP2R1A mRNA
CTD
PMID:18651567
NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
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Ppp2r1b
protein phosphatase 2 scaffold subunit A beta
increases expression
ISO
nickel sulfate results in increased expression of PPP2R1B mRNA
CTD
PMID:16780908
NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
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Ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
increases expression
ISO
nickel sulfate results in increased expression of PPP2R3B mRNA
CTD
PMID:22714537
NCBI chr14:88,507...95,750
Ensembl chr14:89,176...95,750
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Ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
increases expression
ISO
nickel sulfate results in increased expression of PPP2R5B mRNA
CTD
PMID:17382205
NCBI chr 1:203,527,268...203,535,442
Ensembl chr 1:203,527,270...203,535,416
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Prdm1
PR/SET domain 1
increases expression
ISO
nickel sulfate results in increased expression of PRDM1 mRNA
CTD
PMID:22714537
NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
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Prdx3
peroxiredoxin 3
decreases expression
ISO
nickel sulfate results in decreased expression of PRDX3 mRNA
CTD
PMID:17374397
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Prickle1
prickle planar cell polarity protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of PRICKLE1 mRNA
CTD
PMID:22714537
NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113
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Prkab2
protein kinase AMP-activated non-catalytic subunit beta 2
decreases expression
ISO
nickel sulfate results in decreased expression of PRKAB2 mRNA
CTD
PMID:22714537
NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
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Prkar2b
protein kinase cAMP-dependent type II regulatory subunit beta
increases expression
ISO
nickel sulfate results in increased expression of PRKAR2B mRNA
CTD
PMID:22714537
NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
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Prkx
protein kinase cAMP-dependent X-linked catalytic subunit
increases expression
ISO
nickel sulfate results in increased expression of PRKX mRNA
CTD
PMID:22714537
NCBI chr X:41,823,349...41,866,844
Ensembl chr X:41,823,355...41,866,669
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Prnp
prion protein
decreases expression
ISO
nickel sulfate results in decreased expression of PRNP mRNA
CTD
PMID:22714537
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Pros1
protein S
decreases expression
ISO
nickel sulfate results in decreased expression of PROS1 mRNA
CTD
PMID:22714537
NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286
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Prps2
phosphoribosyl pyrophosphate synthetase 2
increases expression
ISO
nickel sulfate results in increased expression of PRPS2 mRNA
CTD
PMID:22714537
NCBI chr X:26,975,915...27,013,184
Ensembl chr X:26,976,061...27,013,181
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Prr16
proline rich 16
increases expression
ISO
nickel sulfate results in increased expression of PRR16 mRNA
CTD
PMID:22714537
NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329
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Prrg1
proline rich and Gla domain 1
decreases expression
ISO
nickel sulfate results in decreased expression of PRRG1 mRNA
CTD
PMID:22714537
NCBI chr X:42,494,256...42,606,612
Ensembl chr X:42,494,256...42,606,588
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Prrg4
proline rich and Gla domain 4
increases expression
ISO
nickel sulfate results in increased expression of PRRG4 mRNA
CTD
PMID:22714537
NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
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Prss8
serine protease 8
increases expression
ISO
nickel sulfate results in increased expression of PRSS8 mRNA
CTD
PMID:18651567
NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
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Prtg
protogenin
increases expression
ISO
nickel sulfate results in increased expression of PRTG mRNA
CTD
PMID:22714537
NCBI chr 8:73,548,440...73,657,945
Ensembl chr 8:73,548,466...73,653,259
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Prune2
prune homolog 2 with BCH domain
decreases expression
ISO
nickel sulfate results in decreased expression of PRUNE2 mRNA
CTD
PMID:22714537
NCBI chr 1:214,352,586...214,624,848
Ensembl chr 1:214,352,955...214,622,650
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Psd3
pleckstrin and Sec7 domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of PSD3 mRNA
CTD
PMID:22714537
NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547
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Psma4
proteasome 20S subunit alpha 4
decreases expression
ISO
nickel sulfate results in decreased expression of PSMA4 mRNA
CTD
PMID:18651567
NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
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Psma5
proteasome 20S subunit alpha 5
decreases expression
ISO
nickel sulfate results in decreased expression of PSMA5 mRNA
CTD
PMID:17374397
NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
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Psmb8
proteasome 20S subunit beta 8
increases expression
ISO
nickel sulfate results in increased expression of PSMB8 mRNA
CTD
PMID:22714537
NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
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Psmb9
proteasome 20S subunit beta 9
increases expression
ISO
nickel sulfate results in increased expression of PSMB9 mRNA
CTD
PMID:22714537
NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
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Psmf1
proteasome inhibitor subunit 1
decreases expression
ISO
nickel sulfate results in decreased expression of PSMF1 mRNA
CTD
PMID:22714537
NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546
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Pten
phosphatase and tensin homolog
increases expression
ISO
nickel sulfate results in increased expression of PTEN mRNA
CTD
PMID:16780908
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Ptger2
prostaglandin E receptor 2
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of PTGER2 mRNA [[Dinoprostone results in increased activity of PTGER2 protein] which results in increased susceptibility to nickel sulfate] which results in increased secretion of CXCL8 protein; [Dinoprostone results in increased activity of PTGER2 protein] which results in increased susceptibility to nickel sulfate; nickel sulfate promotes the reaction [[Dinoprostone results in increased activity of PTGER2 protein] which results in increased chemical synthesis of Cyclic AMP]
CTD
PMID:16100012 PMID:23526216
NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
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Ptger3
prostaglandin E receptor 3
decreases expression
ISO
nickel sulfate results in decreased expression of PTGER3 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
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Ptger4
prostaglandin E receptor 4
multiple interactions increases expression
ISO
[[Dinoprostone results in increased activity of PTGER4 protein] which results in increased susceptibility to nickel sulfate] which results in increased secretion of CXCL8 protein; [Dinoprostone results in increased activity of PTGER4 protein] which results in increased susceptibility to nickel sulfate; nickel sulfate promotes the reaction [[Dinoprostone results in increased activity of PTGER4 protein] which results in increased chemical synthesis of Cyclic AMP] nickel sulfate results in increased expression of PTGER4 mRNA
CTD
PMID:22714537 PMID:23526216
NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
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Ptgr1
prostaglandin reductase 1
increases expression
ISO
nickel sulfate results in increased expression of PTGR1 mRNA
CTD
PMID:20566472
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of PTGS2 mRNA puerarin inhibits the reaction [nickel sulfate results in increased expression of PTGS2 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of PTGS2 protein]; [nickel sulfate co-treated with Dinoprostone] results in increased expression of PTGS2 protein; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of PTGS2 protein; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 mRNA]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 protein]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of PTGS2 mRNA]; PTGS2 mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL1 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL5 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL8 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of PTGS2 protein]
CTD
PMID:16780908 PMID:18096868 PMID:18832182 PMID:20600219 PMID:26607348
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptma
prothymosin alpha
decreases expression
ISO
nickel sulfate results in decreased expression of PTMA mRNA
CTD
PMID:18651567
NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
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Ptpn18
protein tyrosine phosphatase, non-receptor type 18
increases expression
ISO
nickel sulfate results in increased expression of PTPN18 mRNA
CTD
PMID:22714537
NCBI chr 9:36,672,325...36,689,963
Ensembl chr 9:36,672,362...36,690,995
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Ptpn6
protein tyrosine phosphatase, non-receptor type 6
increases expression
ISO
nickel sulfate results in increased expression of PTPN6 mRNA
CTD
PMID:22714537
NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
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Ptpra
protein tyrosine phosphatase, receptor type, A
decreases expression
ISO
nickel sulfate results in decreased expression of PTPRA mRNA
CTD
PMID:22714537
NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728
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Ptprb
protein tyrosine phosphatase, receptor type, B
decreases expression
ISO
nickel sulfate results in decreased expression of PTPRB mRNA
CTD
PMID:22714537
NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
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Ptprg
protein tyrosine phosphatase, receptor type, G
decreases expression
ISO
nickel sulfate results in decreased expression of PTPRG mRNA
CTD
PMID:22714537
NCBI chr15:12,871,706...13,552,186
Ensembl chr15:12,871,721...13,554,094
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Pum3
pumilio RNA-binding family member 3
decreases expression
ISO
nickel sulfate results in decreased expression of PUM3 mRNA
CTD
PMID:22714537
NCBI chr 1:225,074,332...225,113,995
Ensembl chr 1:225,074,333...225,114,025
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Pxdc1
PX domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of PXDC1 mRNA
CTD
PMID:18651567
NCBI chr17:30,275,998...30,304,971
Ensembl chr17:30,276,377...30,304,973
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Pxylp1
2-phosphoxylose phosphatase 1
decreases expression
ISO
nickel sulfate results in decreased expression of PXYLP1 mRNA
CTD
PMID:22714537
NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064
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Pygb
glycogen phosphorylase B
decreases expression
ISO
nickel sulfate results in decreased expression of PYGB mRNA
CTD
PMID:22714537
NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
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Qpct
glutaminyl-peptide cyclotransferase
decreases expression
ISO
nickel sulfate results in decreased expression of QPCT mRNA
CTD
PMID:22714537
NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711
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Rab27b
RAB27B, member RAS oncogene family
increases expression
ISO
nickel sulfate results in increased expression of RAB27B mRNA
CTD
PMID:22714537
NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180
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Rab32
RAB32, member RAS oncogene family
decreases expression
ISO
nickel sulfate results in decreased expression of RAB32 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
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Rab3d
RAB3D, member RAS oncogene family
increases expression
ISO
nickel sulfate results in increased expression of RAB3D mRNA
CTD
PMID:22714537
NCBI chr 8:20,438,622...20,449,269
Ensembl chr 8:20,439,294...20,449,185
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Rab42
RAB42, member RAS oncogene family
decreases expression
ISO
nickel sulfate results in decreased expression of RAB42 mRNA
CTD
PMID:22714537
NCBI chr 5:144,497,159...144,498,829
Ensembl chr 5:144,496,215...144,498,848
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Rab43
RAB43, member RAS oncogene family
increases expression
ISO
nickel sulfate results in increased expression of RAB43 mRNA
CTD
PMID:22714537
NCBI chr 4:120,249,650...120,269,174
Ensembl chr 4:120,249,879...120,269,174
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Rab8b
RAB8B, member RAS oncogene family
increases expression
ISO
nickel sulfate results in increased expression of RAB8B mRNA
CTD
PMID:16780908
NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384
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Rab9b
RAB9B, member RAS oncogene family
decreases expression
ISO
nickel sulfate results in decreased expression of RAB9B mRNA
CTD
PMID:22714537
NCBI chr X:100,220,897...100,231,591
Ensembl chr X:100,220,894...100,231,701
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Ralb
RAS like proto-oncogene B
increases expression decreases expression
ISO
nickel sulfate results in increased expression of RALB mRNA nickel sulfate results in decreased expression of RALB mRNA
CTD
PMID:16780908
NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
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Ralgapa2
Ral GTPase activating protein catalytic subunit alpha 2
decreases expression
ISO
nickel sulfate results in decreased expression of RALGAPA2 mRNA
CTD
PMID:22714537
NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916
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Ralgdsl1
ral guanine nucleotide dissociation stimulator like 1
decreases expression
ISO
nickel sulfate results in decreased expression of RGL1 mRNA
CTD
PMID:22714537
NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191
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Ralgdsl2
ral guanine nucleotide dissociation stimulator like 2
increases expression
ISO
nickel sulfate results in increased expression of RGL2 mRNA
CTD
PMID:22714537
NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911
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Raly
RALY heterogeneous nuclear ribonucleoprotein
increases expression
ISO
nickel sulfate results in increased expression of RALY mRNA
CTD
PMID:18651567
NCBI chr 3:143,306,039...143,370,542
Ensembl chr 3:143,306,300...143,370,539
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Ramp1
receptor activity modifying protein 1
increases expression
ISO
nickel sulfate results in increased expression of RAMP1 mRNA
CTD
PMID:16780908
NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
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Ranbp6
RAN binding protein 6
decreases expression
ISO
nickel sulfate results in decreased expression of RANBP6 mRNA
CTD
PMID:22714537
NCBI chr 1:227,572,394...227,576,915
Ensembl chr 1:227,572,105...227,576,942
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Rap1gds1
Rap1 GTPase-GDP dissociation stimulator 1
decreases expression
ISO
nickel sulfate results in decreased expression of RAP1GDS1 mRNA
CTD
PMID:22714537
NCBI chr 2:227,500,366...227,645,213
Ensembl chr 2:227,500,367...227,645,169
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Rasgrp1
RAS guanyl releasing protein 1
increases expression
ISO
nickel sulfate results in increased expression of RASGRP1 mRNA
CTD
PMID:22714537
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
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Raver2
ribonucleoprotein, PTB-binding 2
increases expression
ISO
nickel sulfate results in increased expression of RAVER2 mRNA
CTD
PMID:22714537
NCBI chr 5:115,700,985...115,780,465
Ensembl chr 5:115,701,326...115,778,792
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Rbbp9
RB binding protein 9, serine hydrolase
decreases expression
ISO
nickel sulfate results in decreased expression of RBBP9 mRNA
CTD
PMID:22714537
NCBI chr 3:131,925,095...131,939,042
Ensembl chr 3:131,925,341...131,932,156
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Rbck1
RANBP2-type and C3HC4-type zinc finger containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of RBCK1 mRNA
CTD
PMID:22714537
NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
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Rbm17
RNA binding motif protein 17
decreases expression
ISO
nickel sulfate results in decreased expression of RBM17 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014
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Rbm24
RNA binding motif protein 24
increases expression
ISO
nickel sulfate results in increased expression of RBM24 mRNA
CTD
PMID:22714537
NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102
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Rbms3
RNA binding motif, single stranded interacting protein 3
decreases expression
ISO
nickel sulfate results in decreased expression of RBMS3 mRNA
CTD
PMID:22714537
NCBI chr 8:116,305,227...117,625,730
Ensembl chr 8:116,309,882...117,625,423
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Rbpj
recombination signal binding protein for immunoglobulin kappa J region
decreases expression
ISO
nickel sulfate results in decreased expression of RBPJ mRNA
CTD
PMID:17374397 PMID:22714537
NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
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Rcan1
regulator of calcineurin 1
increases expression
ISO
nickel sulfate results in increased expression of RCAN1 mRNA
CTD
PMID:16780908
NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
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Rcvrn
recoverin
decreases expression
ISO
nickel sulfate results in decreased expression of RCVRN mRNA
CTD
PMID:16780908
NCBI chr10:52,388,706...52,396,454
Ensembl chr10:52,388,706...52,396,453
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Rdh11
retinol dehydrogenase 11
decreases expression
ISO
nickel sulfate results in decreased expression of RDH11 mRNA
CTD
PMID:18651567
NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
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Reck
reversion-inducing-cysteine-rich protein with kazal motifs
decreases expression
ISO
nickel sulfate results in decreased expression of RECK mRNA
CTD
PMID:22714537
NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
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Reg3g
regenerating family member 3 gamma
increases expression
ISO
nickel sulfate results in increased expression of REG3G mRNA
CTD
PMID:16166746
NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
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Rel
REL proto-oncogene, NF-kB subunit
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of REL mRNA nickel sulfate results in increased expression of REL mRNA
CTD
PMID:16780908
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions affects localization
ISO
[nickel sulfate results in increased degradation of NFKBIA protein] which results in increased activity of RELA protein; nickel sulfate results in increased phosphorylation of and affects the localization of RELA protein puerarin inhibits the reaction [nickel sulfate affects the localization of RELA protein]
CTD
PMID:17636246 PMID:25673294 PMID:26607348
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Reps2
RALBP1 associated Eps domain containing 2
increases expression
ISO
nickel sulfate results in increased expression of REPS2 mRNA
CTD
PMID:22714537
NCBI chr X:32,049,455...32,322,317
Ensembl chr X:32,049,399...32,317,414
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Resf1
retroelement silencing factor 1
increases expression
ISO
nickel sulfate results in increased expression of RESF1 mRNA
CTD
PMID:22714537
NCBI chr 4:182,325,913...182,362,054
Ensembl chr 4:182,335,454...182,362,054
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Retreg1
reticulophagy regulator 1
increases expression
ISO
nickel sulfate results in increased expression of RETREG1 mRNA
CTD
PMID:22714537
NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898
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Retreg2
reticulophagy regulator family member 2
increases expression
ISO
nickel sulfate results in increased expression of RETREG2 mRNA
CTD
PMID:22714537
NCBI chr 9:76,640,282...76,646,400
Ensembl chr 9:76,640,319...76,646,395
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Rgs1
regulator of G-protein signaling 1
increases expression
ISO
nickel sulfate results in increased expression of RGS1 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
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Rgs16
regulator of G-protein signaling 16
increases expression
ISO
nickel sulfate results in increased expression of RGS16 mRNA
CTD
PMID:16780908
NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
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Rgs9
regulator of G-protein signaling 9
increases expression
ISO
nickel sulfate results in increased expression of RGS9 mRNA
CTD
PMID:22714537
NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
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Rhebl1
RHEB like 1
increases expression
ISO
nickel sulfate results in increased expression of RHEBL1 mRNA
CTD
PMID:22714537
NCBI chr 7:130,026,255...130,031,127
Ensembl chr 7:130,026,341...130,030,248
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Rhobtb1
Rho-related BTB domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of RHOBTB1 mRNA
CTD
PMID:22714537
NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012
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Rhoc
ras homolog family member C
increases expression
ISO
nickel sulfate results in increased expression of RHOC mRNA
CTD
PMID:16314067
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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Rhpn2
rhophilin, Rho GTPase binding protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of RHPN2 mRNA
CTD
PMID:16780908
NCBI chr 1:87,991,143...88,051,895
Ensembl chr 1:87,991,144...88,051,902
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Rictor
RPTOR independent companion of MTOR, complex 2
increases expression
ISO
nickel sulfate results in increased expression of RICTOR mRNA
CTD
PMID:22714537
NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
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Ripk2
receptor-interacting serine-threonine kinase 2
increases expression
ISO
nickel sulfate results in increased expression of RIPK2 mRNA
CTD
PMID:22714537
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
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Ripk4
receptor-interacting serine-threonine kinase 4
increases expression
ISO
nickel sulfate results in increased expression of RIPK4 mRNA
CTD
PMID:22714537
NCBI chr11:37,122,555...37,144,799
Ensembl chr11:37,122,565...37,144,799
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Rit1
Ras-like without CAAX 1
increases expression
ISO
nickel sulfate results in increased expression of RIT1 mRNA
CTD
PMID:16314067
NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
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Rnase6
ribonuclease A family member 6
decreases expression
ISO
nickel sulfate results in decreased expression of RNASE6 mRNA
CTD
PMID:16780908
NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328
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Rnaset2
ribonuclease T2
increases expression
ISO
nickel sulfate results in increased expression of RNASET2 mRNA
CTD
PMID:22714537
NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147
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Rnf157
ring finger protein 157
increases expression
ISO
nickel sulfate results in increased expression of RNF157 mRNA
CTD
PMID:22714537
NCBI chr10:101,571,972...101,639,874
Ensembl chr10:101,566,295...101,639,942
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Rnf166
ring finger protein 166
increases expression
ISO
nickel sulfate results in increased expression of RNF166 mRNA
CTD
PMID:22714537
NCBI chr19:50,529,434...50,539,274
Ensembl chr19:50,529,434...50,539,274
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Rnf213
ring finger protein 213
increases expression
ISO
nickel sulfate results in increased expression of RNF213 mRNA
CTD
PMID:22714537
NCBI chr10:104,656,329...104,755,669
Ensembl chr10:104,656,883...104,757,918
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Rnf24
ring finger protein 24
decreases expression
ISO
nickel sulfate results in decreased expression of RNF24 mRNA
CTD
PMID:22714537
NCBI chr 3:118,520,459...118,575,213
Ensembl chr 3:118,525,349...118,541,080
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Rnls
renalase, FAD-dependent amine oxidase
decreases expression
ISO
nickel sulfate results in decreased expression of RNLS mRNA
CTD
PMID:22714537
NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
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Rnpepl1
arginyl aminopeptidase like 1
increases expression
ISO
nickel sulfate results in increased expression of RNPEPL1 mRNA
CTD
PMID:22714537
NCBI chr 9:93,476,600...93,486,331
Ensembl chr 9:93,472,390...93,486,331
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Robo2
roundabout guidance receptor 2
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ROBO2 mRNA
CTD
PMID:31734292
NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536
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Ropn1l
rhophilin associated tail protein 1-like
increases expression
ISO
nickel sulfate results in increased expression of ROPN1L mRNA
CTD
PMID:22714537
NCBI chr 2:82,442,645...82,453,332
Ensembl chr 2:82,441,891...82,453,485
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Ror1
receptor tyrosine kinase-like orphan receptor 1
decreases expression
ISO
nickel sulfate results in decreased expression of ROR1 mRNA
CTD
PMID:22714537
NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
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Rpl10
ribosomal protein L10
decreases expression
ISO
nickel sulfate results in decreased expression of RPL10 mRNA
CTD
PMID:22714537
NCBI chr X:152,054,562...152,056,769
Ensembl chr X:152,054,452...152,056,761
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Rpl23
ribosomal protein L23
decreases expression
ISO
nickel sulfate results in decreased expression of RPL23 mRNA
CTD
PMID:18651567
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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Rps6ka5
ribosomal protein S6 kinase A5
increases expression
ISO
nickel sulfate results in increased expression of RPS6KA5 mRNA
CTD
PMID:22714537
NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
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Rps6kb2
ribosomal protein S6 kinase B2
increases expression
ISO
nickel sulfate results in increased expression of RPS6KB2 mRNA
CTD
PMID:18651567
NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078
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Rrbp1
ribosome binding protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of RRBP1 mRNA
CTD
PMID:22714537
NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981
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RT1-CE5
RT1 class I, locus CE5
increases expression
ISO
nickel sulfate results in increased expression of HLA-F mRNA
CTD
PMID:22714537
NCBI chr20:3,403,418...3,479,476
G
RT1-DMa
RT1 class II, locus DMa
decreases expression
ISO
nickel sulfate results in decreased expression of HLA-DMA mRNA
CTD
PMID:16780908
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
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Rtkn
rhotekin
increases expression
ISO
nickel sulfate results in increased expression of RTKN mRNA
CTD
PMID:22714537
NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952
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Rtl3
retrotransposon Gag like 3
decreases expression
ISO
nickel sulfate results in decreased expression of RTL3 mRNA
CTD
PMID:22714537
NCBI chr X:71,947,343...71,951,008
Ensembl chr X:71,948,253...71,950,121
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Rubcn
rubicon autophagy regulator
increases expression
ISO
nickel sulfate results in increased expression of RUBCN mRNA
CTD
PMID:16780908
NCBI chr11:67,907,534...67,964,347
Ensembl chr11:67,907,516...67,964,314
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Rxrb
retinoid X receptor beta
increases expression
ISO
nickel sulfate results in increased expression of RXRB mRNA
CTD
PMID:22714537
NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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S100a10
S100 calcium binding protein A10
increases expression
ISO
nickel sulfate results in increased expression of S100A10 mRNA
CTD
PMID:16314067
NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
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S100a8
S100 calcium binding protein A8
affects expression
ISO
nickel sulfate affects the expression of S100A8 mRNA
CTD
PMID:12718980
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
increases expression
ISO
nickel sulfate results in increased expression of S100A9 mRNA
CTD
PMID:16100012
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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S100b
S100 calcium binding protein B
decreases expression
ISO
nickel sulfate results in decreased expression of S100B mRNA
CTD
PMID:17374397
NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
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S1pr1
sphingosine-1-phosphate receptor 1
multiple interactions decreases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of S1PR1 mRNA nickel sulfate results in decreased expression of S1PR1 mRNA
CTD
PMID:18832182 PMID:22714537
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
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S1pr3
sphingosine-1-phosphate receptor 3
increases expression
ISO
nickel sulfate results in increased expression of S1PR3 mRNA
CTD
PMID:22714537
NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
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Sacm1l
SAC1 like phosphatidylinositide phosphatase
decreases expression
ISO
nickel sulfate results in decreased expression of SACM1L mRNA
CTD
PMID:16780908
NCBI chr 8:123,176,017...123,232,413
Ensembl chr 8:123,172,536...123,232,413
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Sacs
sacsin molecular chaperone
decreases expression
ISO
nickel sulfate results in decreased expression of SACS mRNA
CTD
PMID:22714537
NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
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Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
increases expression
ISO
nickel sulfate results in increased expression of SAMSN1 mRNA
CTD
PMID:16780908
NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900
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Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
nickel sulfate results in increased expression of SAT1 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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Satb1
SATB homeobox 1
increases expression
ISO
nickel sulfate results in increased expression of SATB1 mRNA
CTD
PMID:16780908
NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
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Satb2
SATB homeobox 2
increases expression
ISO
nickel sulfate results in increased expression of SATB2 mRNA
CTD
PMID:22714537
NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
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Sc5d
sterol-C5-desaturase
increases expression
ISO
nickel sulfate results in increased expression of SC5D mRNA
CTD
PMID:22714537
NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
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Scd
stearoyl-CoA desaturase
increases expression
ISO
nickel sulfate results in increased expression of SCD mRNA
CTD
PMID:22714537
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Scd2
stearoyl-Coenzyme A desaturase 2
decreases expression
ISO
nickel sulfate results in decreased expression of SCD2 mRNA
CTD
PMID:16100012
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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Scg2
secretogranin II
increases expression
ISO
nickel sulfate results in increased expression of SCG2 mRNA
CTD
PMID:22714537
NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097
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Scgb1a1
secretoglobin family 1A member 1
affects expression
ISO
nickel sulfate affects the expression of SCGB1A1 mRNA
CTD
PMID:12718980
NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
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Sdc2
syndecan 2
increases expression
ISO
nickel sulfate results in increased expression of SDC2 mRNA
CTD
PMID:16780908 PMID:17374397 PMID:22714537
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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Sdc4
syndecan 4
increases expression
ISO
nickel sulfate results in increased expression of SDC4 mRNA
CTD
PMID:18651567
NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
decreases expression
ISO
nickel sulfate results in decreased expression of SDR42E1 mRNA
CTD
PMID:22714537
NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901
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Sec23b
Sec23 homolog B, COPII coat complex component
decreases expression
ISO
nickel sulfate results in decreased expression of SEC23B mRNA
CTD
PMID:22714537
NCBI chr 3:131,939,011...131,981,489
Ensembl chr 3:131,939,337...131,981,489
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Sec61b
SEC61 translocon subunit beta
increases expression
ISO
nickel sulfate results in increased expression of SEC61B mRNA
CTD
PMID:18651567
NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804
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Sec61g
Sec61 translocon subunit gamma
increases expression
ISO
nickel sulfate results in increased expression of SEC61G mRNA
CTD
PMID:18651567
NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162
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Sectm1b
secreted and transmembrane 1B
decreases expression
ISO
nickel sulfate results in decreased expression of SECTM1 mRNA
CTD
PMID:22714537
NCBI chr10:106,324,070...106,333,779
Ensembl chr10:106,325,203...106,333,769
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Sel1l3
SEL1L family member 3
decreases expression
ISO
nickel sulfate results in decreased expression of SEL1L3 mRNA
CTD
PMID:22714537
NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
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Selenok
selenoprotein K
increases expression
ISO
nickel sulfate results in increased expression of SELENOK mRNA
CTD
PMID:16780908
NCBI chr16:5,152,066...5,160,648
Ensembl chr16:5,152,066...5,159,188
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Selp
selectin P
increases expression
ISO
nickel sulfate results in increased expression of SELP mRNA
CTD
PMID:16166746
NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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Sema4c
semaphorin 4C
increases expression
ISO
nickel sulfate results in increased expression of SEMA4C mRNA
CTD
PMID:16314067
NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128
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Sema4d
semaphorin 4D
increases expression
ISO
nickel sulfate results in increased expression of SEMA4D mRNA
CTD
PMID:22714537
NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
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Sema5a
semaphorin 5A
increases expression
ISO
nickel sulfate results in increased expression of SEMA5A mRNA
CTD
PMID:16780908
NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
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Sema6b
semaphorin 6B
increases expression
ISO
nickel sulfate results in increased expression of SEMA6B mRNA
CTD
PMID:22714537
NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521
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Sema6d
semaphorin 6D
increases expression
ISO
nickel sulfate results in increased expression of SEMA6D mRNA
CTD
PMID:22714537
NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094
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Sema7a
semaphorin 7A (John Milton Hagen blood group)
decreases expression
ISO
nickel sulfate results in decreased expression of SEMA7A mRNA
CTD
PMID:22714537
NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536
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Septin11
septin 11
decreases expression
ISO
nickel sulfate results in decreased expression of SEPTIN11 mRNA
CTD
PMID:17374397
NCBI chr14:14,844,759...14,990,856
Ensembl chr14:14,844,580...14,990,853
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Serbp1
Serpine1 mRNA binding protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of SERBP1 mRNA
CTD
PMID:17374397
NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
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Serp2
stress-associated endoplasmic reticulum protein family member 2
decreases expression
ISO
nickel sulfate results in decreased expression of SERP2 mRNA
CTD
PMID:22714537
NCBI chr15:51,879,882...51,903,958
Ensembl chr15:51,879,877...51,904,785
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Serpinb2
serpin family B member 2
decreases expression
ISO
nickel sulfate results in decreased expression of SERPINB2 mRNA
CTD
PMID:22714537
NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpinb3
serpin family B member 3
decreases expression
ISO
nickel sulfate results in decreased expression of SERPINB3 mRNA
CTD
PMID:18651567
NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
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Serpinb3a
serpin family B member 3A
decreases expression
ISO
nickel sulfate results in decreased expression of SERPINB4 mRNA
CTD
PMID:18651567
NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
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Serpinb7
serpin family B member 7
decreases expression
ISO
nickel sulfate results in decreased expression of SERPINB7 mRNA
CTD
PMID:22714537
NCBI chr13:23,369,830...23,442,205
Ensembl chr13:23,395,671...23,442,205
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Serpinb9
serpin family B member 9
increases expression
ISO
nickel sulfate results in increased expression of SERPINB9 mRNA
CTD
PMID:22714537
NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
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Serpine1
serpin family E member 1
increases expression
ISO
nickel sulfate results in increased expression of SERPINE1 mRNA
CTD
PMID:16100012
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpine2
serpin family E member 2
increases expression
ISO
nickel sulfate results in increased expression of SERPINE2 mRNA
CTD
PMID:22714537
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Serpinh1
serpin family H member 1
decreases expression
ISO
nickel sulfate results in decreased expression of SERPINH1 mRNA
CTD
PMID:22714537
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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Sestd1
SEC14 and spectrin domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of SESTD1 mRNA
CTD
PMID:22714537
NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
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Sfn
stratifin
increases expression
ISO
nickel sulfate results in increased expression of SFN mRNA
CTD
PMID:16100012 PMID:16166746
NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
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Sfpq
splicing factor proline and glutamine rich
increases expression
ISO
nickel sulfate results in increased expression of SFPQ mRNA
CTD
PMID:18651567
NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
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Sftpa1
surfactant protein A1
decreases expression
ISO
nickel sulfate results in decreased expression of SFTPA1 mRNA
CTD
PMID:11893692
NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
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Sftpb
surfactant protein B
affects expression affects response to substance multiple interactions decreases expression
ISO
nickel sulfate affects the expression of SFTPB mRNA SFTPB protein affects the susceptibility to nickel sulfate TGFA protein inhibits the reaction [nickel sulfate results in decreased expression of SFTPB protein] nickel sulfate results in decreased expression of SFTPB mRNA; nickel sulfate results in decreased expression of SFTPB protein
CTD
PMID:11893692 PMID:11954676 PMID:12718980 PMID:19131640
NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
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Sftpc
surfactant protein C
decreases expression affects expression
ISO
nickel sulfate results in decreased expression of SFTPC mRNA nickel sulfate affects the expression of SFTPC mRNA
CTD
PMID:11893692 PMID:12718980
NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
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Sfxn2
sideroflexin 2
decreases expression
ISO
nickel sulfate results in decreased expression of SFXN2 mRNA
CTD
PMID:22714537
NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411 Ensembl chr 1:245,447,015...245,468,411
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Sgk1
serum/glucocorticoid regulated kinase 1
increases expression
ISO
nickel sulfate results in increased expression of SGK1 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sgms2
sphingomyelin synthase 2
decreases expression
ISO
nickel sulfate results in decreased expression of SGMS2 mRNA
CTD
PMID:22714537
NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546
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Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
increases expression
ISO
nickel sulfate results in increased expression of SGTA mRNA
CTD
PMID:18651567
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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Sh3gl1
SH3 domain containing GRB2 like 1, endophilin A2
increases expression
ISO
nickel sulfate results in increased expression of SH3GL1 mRNA
CTD
PMID:18651567
NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
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Shank2
SH3 and multiple ankyrin repeat domains 2
decreases expression
ISO
nickel sulfate results in decreased expression of SHANK2 mRNA
CTD
PMID:22714537
NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
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Shisal1
shisa like 1
increases expression
ISO
nickel sulfate results in increased expression of SHISAL1 mRNA
CTD
PMID:22714537
NCBI chr 7:115,506,947...115,611,518
Ensembl chr 7:115,509,035...115,575,449
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Sik1
salt-inducible kinase 1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of SIK1 mRNA
CTD
PMID:31734292
NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
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Sim1
SIM bHLH transcription factor 1
increases expression
ISO
nickel sulfate results in increased expression of SIM1 mRNA
CTD
PMID:22714537
NCBI chr20:53,827,601...53,907,219
Ensembl chr20:53,828,364...53,907,212
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Simc1
SUMO-interacting motifs containing 1
increases expression
ISO
nickel sulfate results in increased expression of SIMC1 mRNA
CTD
PMID:22714537
NCBI chr17:10,061,752...10,106,938
Ensembl chr17:10,061,757...10,106,910
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Sirpa
signal-regulatory protein alpha
decreases expression
ISO
nickel sulfate results in decreased expression of SIRPA mRNA
CTD
PMID:22714537
NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
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Skap2
src kinase associated phosphoprotein 2
increases expression
ISO
nickel sulfate results in increased expression of SKAP2 mRNA
CTD
PMID:22714537
NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
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Skic2
SKI2 subunit of superkiller complex
increases expression
ISO
nickel sulfate results in increased expression of SKIC2 mRNA
CTD
PMID:22714537
NCBI chr20:3,982,494...3,993,261
Ensembl chr20:3,982,593...3,993,261
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Slamf7
SLAM family member 7
decreases expression
ISO
nickel sulfate results in decreased expression of SLAMF7 mRNA
CTD
PMID:22714537
NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105
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Slamf8
SLAM family member 8
decreases expression
ISO
nickel sulfate results in decreased expression of SLAMF8 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
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Slc10a4
solute carrier family 10, member 4
decreases expression
ISO
nickel sulfate results in decreased expression of SLC10A4 mRNA
CTD
PMID:22714537
NCBI chr14:35,198,149...35,203,863
Ensembl chr14:35,197,886...35,203,729
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Slc12a7
solute carrier family 12 member 7
increases expression
ISO
nickel sulfate results in increased expression of SLC12A7 mRNA
CTD
PMID:22714537
NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
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Slc16a10
solute carrier family 16 member 10
increases expression
ISO
nickel sulfate results in increased expression of SLC16A10 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
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Slc16a12
solute carrier family 16, member 12
decreases expression
ISO
nickel sulfate results in decreased expression of SLC16A12 mRNA
CTD
PMID:22714537
NCBI chr 1:232,184,004...232,262,170
Ensembl chr 1:232,185,907...232,262,141
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Slc16a13
solute carrier family 16, member 13
increases expression
ISO
nickel sulfate results in increased expression of SLC16A13 mRNA
CTD
PMID:22714537
NCBI chr10:54,925,973...54,937,860
Ensembl chr10:54,926,760...54,937,788
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Slc18b1
solute carrier family 18 member B1
increases expression
ISO
nickel sulfate results in increased expression of SLC18B1 mRNA
CTD
PMID:22714537
NCBI chr 1:21,628,235...21,670,807
Ensembl chr 1:21,628,237...21,670,684
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Slc19a2
solute carrier family 19 member 2
decreases expression
ISO
nickel sulfate results in decreased expression of SLC19A2 mRNA
CTD
PMID:22714537
NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
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Slc22a23
solute carrier family 22, member 23
increases expression
ISO
nickel sulfate results in increased expression of SLC22A23 mRNA
CTD
PMID:22714537
NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790
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Slc23a2
solute carrier family 23 member 2
multiple interactions decreases expression
ISO
Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased expression of SLC23A2 mRNA]
CTD
PMID:16288478 PMID:22714537
NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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Slc25a30
solute carrier family 25, member 30
decreases expression
ISO
nickel sulfate results in decreased expression of SLC25A30 mRNA
CTD
PMID:22714537
NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
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Slc25a5-ps11
solute carrier family 25 member 5, pseudogene 11
increases expression
ISO
nickel sulfate results in increased expression of SLC25A6 mRNA
CTD
PMID:22714537
NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199
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Slc29a4
solute carrier family 29 member 4
increases expression
ISO
nickel sulfate results in increased expression of SLC29A4 mRNA
CTD
PMID:22714537
NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
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Slc2a1
solute carrier family 2 member 1
increases expression
ISO
nickel sulfate results in increased expression of SLC2A1 mRNA
CTD
PMID:16100012
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc2a3
solute carrier family 2 member 3
increases expression
ISO
nickel sulfate results in increased expression of SLC2A3 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc34a2
solute carrier family 34 member 2
decreases expression
ISO
nickel sulfate results in decreased expression of SLC34A2 mRNA
CTD
PMID:16100012
NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
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Slc37a1
solute carrier family 37 member 1
increases expression
ISO
nickel sulfate results in increased expression of SLC37A1 mRNA
CTD
PMID:22714537
NCBI chr20:9,360,501...9,433,895
Ensembl chr20:9,378,836...9,433,892
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Slc37a3
solute carrier family 37, member 3
decreases expression
ISO
nickel sulfate results in decreased expression of SLC37A3 mRNA
CTD
PMID:22714537
NCBI chr 4:68,109,314...68,153,590
Ensembl chr 4:68,081,939...68,153,568
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Slc38a3
solute carrier family 38, member 3
decreases expression
ISO
nickel sulfate results in decreased expression of SLC38A3 mRNA
CTD
PMID:22714537
NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
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Slc38a5
solute carrier family 38, member 5
decreases expression
ISO
nickel sulfate results in decreased expression of SLC38A5 mRNA
CTD
PMID:22714537
NCBI chr X:14,213,727...14,222,498
Ensembl chr X:14,213,729...14,222,498
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Slc40a1
solute carrier family 40 member 1
increases expression
ISO
nickel sulfate results in increased expression of SLC40A1 mRNA
CTD
PMID:22714537
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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Slc43a3
solute carrier family 43, member 3
increases expression decreases expression
ISO
nickel sulfate results in increased expression of SLC43A3 mRNA nickel sulfate results in decreased expression of SLC43A3 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 3:70,008,160...70,030,324
Ensembl chr 3:70,009,313...70,029,749
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Slc46a3
solute carrier family 46, member 3
increases expression
ISO
nickel sulfate results in increased expression of SLC46A3 mRNA
CTD
PMID:22714537
NCBI chr12:7,140,610...7,157,093
Ensembl chr12:7,140,668...7,157,092
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Slc47a1
solute carrier family 47 member 1
increases expression
ISO
nickel sulfate results in increased expression of SLC47A1 mRNA
CTD
PMID:22714537
NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
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Slc4a11
solute carrier family 4 member 11
decreases expression
ISO
nickel sulfate results in decreased expression of SLC4A11 mRNA
CTD
PMID:22714537
NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674
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Slc4a4
solute carrier family 4 member 4
decreases expression
ISO
nickel sulfate results in decreased expression of SLC4A4 mRNA
CTD
PMID:22714537
NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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Slc66a3
solute carrier family 66 member 3
increases expression
ISO
nickel sulfate results in increased expression of SLC66A3 mRNA
CTD
PMID:22714537
NCBI chr 6:39,774,801...39,786,554
Ensembl chr 6:39,774,808...39,786,303
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Slc6a6
solute carrier family 6 member 6
increases expression
ISO
nickel sulfate results in increased expression of SLC6A6 mRNA
CTD
PMID:22714537
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Slc7a1
solute carrier family 7 member 1
multiple interactions
ISO
[nickel sulfate co-treated with Lipopolysaccharides] results in increased expression of SLC7A1 mRNA
CTD
PMID:23415871
NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
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Slc7a11
solute carrier family 7 member 11
increases expression
ISO
nickel sulfate results in increased expression of SLC7A11 mRNA
CTD
PMID:22714537
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slc7a3
solute carrier family 7 member 3
multiple interactions
ISO
[nickel sulfate co-treated with Lipopolysaccharides] results in increased expression of SLC7A3 mRNA
CTD
PMID:23415871
NCBI chr X:66,210,071...66,216,482
Ensembl chr X:66,210,081...66,215,708
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Slc7a5
solute carrier family 7 member 5
increases expression
ISO
nickel sulfate results in increased expression of SLC7A5 mRNA
CTD
PMID:16780908 PMID:17374397 PMID:18651567
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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Slc7a8
solute carrier family 7 member 8
increases expression
ISO
nickel sulfate results in increased expression of SLC7A8 mRNA
CTD
PMID:18651567
NCBI chr15:28,183,013...28,242,717
Ensembl chr15:28,183,015...28,242,717
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Slc8b1
solute carrier family 8 member B1
increases expression
ISO
nickel sulfate results in increased expression of SLC8B1 mRNA
CTD
PMID:22714537
NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031
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Slco4a1
solute carrier organic anion transporter family, member 4a1
increases expression
ISO
nickel sulfate results in increased expression of SLCO4A1 mRNA
CTD
PMID:22714537
NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
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Slit2
slit guidance ligand 2
increases expression
ISO
nickel sulfate results in increased expression of SLIT2 mRNA
CTD
PMID:22714537
NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
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Slx4ip
SLX4 interacting protein
decreases expression
ISO
nickel sulfate results in decreased expression of SLX4IP mRNA
CTD
PMID:22714537
NCBI chr 3:124,220,215...124,396,797
Ensembl chr 3:124,221,198...124,396,797
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Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
decreases expression
ISO
nickel sulfate results in decreased expression of SMARCA2 mRNA
CTD
PMID:22714537
NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
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Smc1a
structural maintenance of chromosomes 1A
decreases expression
ISO
nickel sulfate results in decreased expression of SMC1A mRNA
CTD
PMID:17374397
NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056
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Smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
decreases expression
ISO
nickel sulfate results in decreased expression of SMPDL3A mRNA
CTD
PMID:16100012
NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567
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Smurf1
SMAD specific E3 ubiquitin protein ligase 1
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of SMURF1 mRNA
CTD
PMID:31734292
NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
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Smyd3
SET and MYND domain containing 3
decreases expression
ISO
nickel sulfate results in decreased expression of SMYD3 mRNA
CTD
PMID:22714537
NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253
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Snai1
snail family transcriptional repressor 1
increases expression
ISO
nickel sulfate results in increased expression of SNAI1 mRNA
CTD
PMID:20146380
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snca
synuclein alpha
increases expression
ISO
nickel sulfate results in increased expression of SNCA mRNA
CTD
PMID:22714537
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Sned1
sushi, nidogen and EGF-like domains 1
increases expression
ISO
nickel sulfate results in increased expression of SNED1 mRNA
CTD
PMID:16780908
NCBI chr 9:93,774,087...93,834,003
Ensembl chr 9:93,774,119...93,830,694
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Snora24
small nucleolar RNA, H/ACA box 24
decreases expression
ISO
nickel sulfate results in decreased expression of SNORA24 mRNA
CTD
PMID:22714537
NCBI chr 2:82,490,770...82,490,892
Ensembl chr 2:82,490,770...82,490,892 Ensembl chr 2:82,490,770...82,490,892
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Snord1c
small nucleolar RNA, C/D box 1C
decreases expression
ISO
nickel sulfate results in decreased expression of SNORD1C mRNA
CTD
PMID:22714537
NCBI chr10:101,905,797...101,905,872
Ensembl chr10:101,905,797...101,905,872
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Snord45c
small nucleolar RNA, C/D box 45C
decreases expression
ISO
nickel sulfate results in decreased expression of SNORD45C mRNA
CTD
PMID:22714537
NCBI chr 2:242,850,124...242,850,203
Ensembl chr 2:242,850,124...242,850,203
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Snord60
small nucleolar RNA, C/D box 60
decreases expression
ISO
nickel sulfate results in decreased expression of SNORD60 mRNA
CTD
PMID:22714537
NCBI chr10:13,552,773...13,552,855
Ensembl chr10:13,552,773...13,552,855
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Snrpb
small nuclear ribonucleoprotein polypeptides B and B1
increases expression
ISO
nickel sulfate results in increased expression of SNRPB mRNA
CTD
PMID:18651567
NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339
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Snrpb2
small nuclear ribonucleoprotein polypeptide B2
decreases expression
ISO
nickel sulfate results in decreased expression of SNRPB2 mRNA
CTD
PMID:22714537
NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
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Snx10
sorting nexin 10
increases expression
ISO
nickel sulfate results in increased expression of SNX10 mRNA
CTD
PMID:22714537
NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996
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Snx14
sorting nexin 14
increases expression
ISO
nickel sulfate results in increased expression of SNX14 mRNA
CTD
PMID:16780908
NCBI chr 8:89,283,673...89,390,597
Ensembl chr 8:89,298,114...89,390,580
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Snx5
sorting nexin 5
decreases expression
ISO
nickel sulfate results in decreased expression of SNX5 mRNA
CTD
PMID:22714537
NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192
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Snx9
sorting nexin 9
increases expression
ISO
nickel sulfate results in increased expression of SNX9 mRNA
CTD
PMID:17374397
NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
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Socs3
suppressor of cytokine signaling 3
increases expression
ISO
nickel sulfate results in increased expression of SOCS3 mRNA
CTD
PMID:16780908
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Sod1
superoxide dismutase 1
increases expression decreases activity
ISO
nickel sulfate results in increased expression of SOD1 mRNA nickel sulfate results in decreased activity of SOD1 protein
CTD
PMID:20566472 PMID:35499276
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
increases expression
ISO
nickel sulfate results in increased expression of SOD2 mRNA
CTD
PMID:16314067 PMID:16780908 PMID:20566472
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sod3
superoxide dismutase 3
increases expression
ISO
nickel sulfate results in increased expression of SOD3 mRNA
CTD
PMID:20566472
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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Sorl1
sortilin related receptor 1
increases expression
ISO
nickel sulfate results in increased expression of SORL1 mRNA
CTD
PMID:22714537
NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
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Sox9
SRY-box transcription factor 9
increases expression
ISO
nickel sulfate results in increased expression of SOX9 mRNA
CTD
PMID:18651567
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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Sp3
Sp3 transcription factor
increases expression
ISO
nickel sulfate results in increased expression of SP3 mRNA
CTD
PMID:18651567
NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
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Sphk1
sphingosine kinase 1
multiple interactions increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of SPHK1 mRNA nickel sulfate results in increased expression of SPHK1 mRNA
CTD
PMID:18832182
NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
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Spint2
serine peptidase inhibitor, Kunitz type, 2
decreases expression
ISO
nickel sulfate results in decreased expression of SPINT2 mRNA
CTD
PMID:22714537
NCBI chr 1:84,558,159...84,580,616
Ensembl chr 1:84,558,166...84,580,616
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Spmip4
sperm microtubule inner protein 4
increases expression
ISO
nickel sulfate results in increased expression of SPMIP4 mRNA
CTD
PMID:22714537
NCBI chr 4:79,663,375...79,688,291
Ensembl chr 4:79,663,376...79,689,072
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Spock1
sparc/osteonectin, cwcv and kazal like domains proteoglycan 1
increases expression
ISO
nickel sulfate results in increased expression of SPOCK1 mRNA
CTD
PMID:22714537
NCBI chr17:6,741,504...7,221,685
Ensembl chr17:6,742,273...7,224,935
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Spp1
secreted phosphoprotein 1
increases expression
ISO
nickel sulfate results in increased expression of SPP1 mRNA
CTD
PMID:16100012
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Sprr1a
small proline-rich protein 1A
increases expression
ISO
nickel sulfate results in increased expression of SPRR1A mRNA
CTD
PMID:16100012
NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
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Spry3
sprouty RTK signaling antagonist 3
decreases expression
ISO
nickel sulfate results in decreased expression of SPRY3 mRNA
CTD
PMID:22714537
NCBI chr12:16,663,188...16,673,124
Ensembl chr12:16,663,389...16,672,531
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Spta1
spectrin, alpha, erythrocytic 1
increases expression
ISO
nickel sulfate results in increased expression of SPTA1 mRNA
CTD
PMID:16314067
NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
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Sptlc3
serine palmitoyltransferase, long chain base subunit 3
decreases expression
ISO
nickel sulfate results in decreased expression of SPTLC3 mRNA
CTD
PMID:22714537
NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010
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Sqor
sulfide quinone oxidoreductase
increases expression
ISO
nickel sulfate results in increased expression of SQOR mRNA
CTD
PMID:22714537
NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of SRC mRNA
CTD
PMID:31734292
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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Srgap1
SLIT-ROBO Rho GTPase activating protein 1
increases expression
ISO
nickel sulfate results in increased expression of SRGAP1 mRNA
CTD
PMID:22714537
NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196
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Srp72
signal recognition particle 72
decreases expression
ISO
nickel sulfate results in decreased expression of SRP72 mRNA
CTD
PMID:17374397 PMID:18651567
NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
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Srr
serine racemase
increases expression
ISO
nickel sulfate results in increased expression of SRR mRNA
CTD
PMID:22714537
NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
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Srsf5
serine and arginine rich splicing factor 5
increases expression
ISO
nickel sulfate results in increased expression of SRSF5 mRNA
CTD
PMID:16780908
NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
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Srxn1
sulfiredoxin 1
increases expression decreases expression
ISO
nickel sulfate results in increased expression of SRXN1 mRNA nickel sulfate results in decreased expression of SRXN1 mRNA
CTD
PMID:20566472 PMID:22714537
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Ssbp2
single-stranded DNA binding protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of SSBP2 mRNA
CTD
PMID:22714537
NCBI chr 2:22,650,488...22,938,669
Ensembl chr 2:22,651,258...22,933,696
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St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
increases expression
ISO
nickel sulfate results in increased expression of ST3GAL4 mRNA
CTD
PMID:22714537
NCBI chr 8:33,415,666...33,465,319
Ensembl chr 8:33,415,671...33,524,389
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
increases expression
ISO
nickel sulfate results in increased expression of ST3GAL6 mRNA
CTD
PMID:22714537
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
increases expression
ISO
nickel sulfate results in increased expression of ST8SIA6 mRNA
CTD
PMID:22714537
NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
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Stac
SH3 and cysteine rich domain
decreases expression
ISO
nickel sulfate results in decreased expression of STAC mRNA
CTD
PMID:22714537
NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008
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Stambpl1
STAM binding protein-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of STAMBPL1 mRNA
CTD
PMID:22714537
NCBI chr 1:231,699,620...231,745,034
Ensembl chr 1:231,699,995...231,745,032
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Star
steroidogenic acute regulatory protein
multiple interactions decreases expression
EXP
[CGA protein co-treated with nickel sulfate] results in decreased expression of STAR mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of STAR protein; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of STAR protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of STAR protein]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of STAR protein]; TEMPO inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; TEMPO inhibits the reaction [nickel sulfate results in decreased expression of STAR protein]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of STAR protein] nickel sulfate results in decreased expression of STAR mRNA; nickel sulfate results in decreased expression of STAR protein
CTD
PMID:29567110
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Stat1
signal transducer and activator of transcription 1
decreases expression multiple interactions increases phosphorylation
ISO
nickel sulfate results in decreased expression of STAT1 mRNA Quercetin inhibits the reaction [nickel sulfate results in increased phosphorylation of STAT1 protein] Acetylcysteine inhibits the reaction [nickel sulfate results in increased phosphorylation of STAT1 protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased phosphorylation of STAT1 protein]
CTD
PMID:17374397 PMID:20525893 PMID:25957741
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stat4
signal transducer and activator of transcription 4
increases expression
ISO
nickel sulfate results in increased expression of STAT4 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
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Stat5a
signal transducer and activator of transcription 5A
increases expression
ISO
nickel sulfate results in increased expression of STAT5A mRNA
CTD
PMID:16780908
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
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Stat5b
signal transducer and activator of transcription 5B
increases expression multiple interactions
ISO EXP
nickel sulfate results in increased expression of STAT5B mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of STAT5B mRNA
CTD
PMID:17374397 PMID:31734292
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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Stc1
stanniocalcin 1
increases expression
ISO
nickel sulfate results in increased expression of STC1 mRNA
CTD
PMID:17382205
NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
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Steap2
STEAP2 metalloreductase
increases expression
ISO
nickel sulfate results in increased expression of STEAP2 mRNA
CTD
PMID:22714537
NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
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Steap3
STEAP3 metalloreductase
increases expression
ISO
nickel sulfate results in increased expression of STEAP3 mRNA
CTD
PMID:22714537
NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
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Stk16
serine/threonine kinase 16
increases expression
ISO
nickel sulfate results in increased expression of STK16 mRNA
CTD
PMID:22714537
NCBI chr 9:76,705,591...76,708,859
Ensembl chr 9:76,705,602...76,708,855
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Stk19
serine/threonine kinase 19
increases expression
ISO
nickel sulfate results in increased expression of STK19 mRNA
CTD
PMID:18651567
NCBI chr20:3,995,590...4,005,117
Ensembl chr20:3,995,587...4,005,116
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Stk33
serine/threonine kinase 33
decreases expression
ISO
nickel sulfate results in decreased expression of STK33 mRNA
CTD
PMID:22714537
NCBI chr 1:163,276,176...163,458,580
Ensembl chr 1:163,276,340...163,458,627
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Stk35
serine/threonine kinase 35
decreases expression
ISO
nickel sulfate results in decreased expression of STK35 mRNA
CTD
PMID:22714537
NCBI chr 3:117,016,819...117,049,131
Ensembl chr 3:117,016,950...117,048,066
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Stk38l
serine/threonine kinase 38 like
increases expression
ISO
nickel sulfate results in increased expression of STK38L mRNA
CTD
PMID:22714537
NCBI chr 4:179,616,288...179,693,177
Ensembl chr 4:179,634,275...179,690,983
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Stox1
storkhead box 1
increases expression
ISO
nickel sulfate results in increased expression of STOX1 mRNA
CTD
PMID:22714537
NCBI chr20:30,598,284...30,666,371
Ensembl chr20:30,598,168...30,666,939
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Stox2
storkhead box 2
increases expression
ISO
nickel sulfate results in increased expression of STOX2 mRNA
CTD
PMID:22714537
NCBI chr16:44,848,179...45,087,238
Ensembl chr16:44,848,078...45,085,105
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Sts
steroid sulfatase
decreases expression
ISO
nickel sulfate results in decreased expression of STS mRNA
CTD
PMID:22714537
NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
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Stx11
syntaxin 11
increases expression
ISO
nickel sulfate results in increased expression of STX11 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
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Stx1b
syntaxin 1B
increases expression
ISO
nickel sulfate results in increased expression of STX1B mRNA
CTD
PMID:16780908
NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
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Stxbp2
syntaxin binding protein 2
increases expression
ISO
nickel sulfate results in increased expression of STXBP2 mRNA
CTD
PMID:22714537
NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
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Stxbp6
syntaxin binding protein 6
decreases expression
ISO
nickel sulfate results in decreased expression of STXBP6 mRNA
CTD
PMID:22714537
NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024
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Sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of SUGT1 mRNA nickel sulfate results in increased expression of SUGT1 mRNA
CTD
PMID:16780908
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
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Sulf1
sulfatase 1
increases expression
ISO
nickel sulfate results in increased expression of SULF1 mRNA
CTD
PMID:22714537
NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584
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Sulf2
sulfatase 2
decreases expression
ISO
nickel sulfate results in decreased expression of SULF2 mRNA
CTD
PMID:22714537
NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
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Susd1
sushi domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of SUSD1 mRNA
CTD
PMID:22714537
NCBI chr 5:74,157,653...74,281,171
Ensembl chr 5:74,157,773...74,276,291
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Sytl2
synaptotagmin-like 2
decreases expression
ISO
nickel sulfate results in decreased expression of SYTL2 mRNA
CTD
PMID:22714537
NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222
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Tac3
tachykinin precursor 3
increases expression
ISO
nickel sulfate results in increased expression of TAC3 mRNA
CTD
PMID:16780908
NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170
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Taf1b
TATA-box binding protein associated factor, RNA polymerase I subunit B
decreases expression
ISO
nickel sulfate results in decreased expression of TAF1B mRNA
CTD
PMID:16780908
NCBI chr 6:41,116,980...41,194,593
Ensembl chr 6:41,117,420...41,194,593
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Tagln
transgelin
decreases expression
ISO
nickel sulfate results in decreased expression of TAGLN mRNA
CTD
PMID:22714537
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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Tango2
transport and golgi organization 2 homolog
increases expression
ISO
nickel sulfate results in increased expression of TANGO2 mRNA
CTD
PMID:22714537
NCBI chr11:82,645,978...82,692,574
Ensembl chr11:82,645,974...82,692,574
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Tap1
transporter 1, ATP binding cassette subfamily B member
increases expression multiple interactions
ISO EXP
nickel sulfate results in increased expression of TAP1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of TAP1 mRNA
CTD
PMID:22714537 PMID:31734292
NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
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Tapbp
TAP binding protein
increases expression
ISO
nickel sulfate results in increased expression of TAPBP mRNA
CTD
PMID:22714537
NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181
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Tas2r106
taste receptor, type 2, member 106
decreases expression
ISO
nickel sulfate results in decreased expression of TAS2R10 mRNA
CTD
PMID:22714537
NCBI chr 4:165,313,210...165,314,133
Ensembl chr 4:165,313,210...165,314,133
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Tasp1
taspase 1
decreases expression
ISO
nickel sulfate results in decreased expression of TASP1 mRNA
CTD
PMID:22714537
NCBI chr 3:127,176,416...127,408,039
Ensembl chr 3:127,176,692...127,399,600
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Tbc1d13
TBC1 domain family, member 13
increases expression
ISO
nickel sulfate results in increased expression of TBC1D13 mRNA
CTD
PMID:16780908
NCBI chr 3:13,408,944...13,425,524
Ensembl chr 3:13,408,920...13,425,517
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Tbc1d20
TBC1 domain family, member 20
decreases expression
ISO
nickel sulfate results in decreased expression of TBC1D20 mRNA
CTD
PMID:22714537
NCBI chr 3:140,768,537...140,787,010
Ensembl chr 3:140,768,537...140,785,121
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Tcea3
transcription elongation factor A3
decreases expression
ISO
nickel sulfate results in decreased expression of TCEA3 mRNA
CTD
PMID:22714537
NCBI chr 5:148,476,941...148,509,452
Ensembl chr 5:148,476,941...148,509,448
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Tcf25
transcription factor 25
increases expression
ISO
nickel sulfate results in increased expression of TCF25 mRNA
CTD
PMID:22714537
NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723
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Tcf4
transcription factor 4
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of TCF4 mRNA nickel sulfate results in increased expression of TCF4 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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Tcf7l1
transcription factor 7 like 1
increases expression
ISO
nickel sulfate results in increased expression of TCF7L1 mRNA
CTD
PMID:22714537
NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287
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Tctn1
tectonic family member 1
increases expression
ISO
nickel sulfate results in increased expression of TCTN1 mRNA
CTD
PMID:22714537
NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267
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Tec
tec protein tyrosine kinase
decreases expression
ISO
nickel sulfate results in decreased expression of TEC mRNA
CTD
PMID:16100012
NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
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Tenm3
teneurin transmembrane protein 3
decreases expression
ISO
nickel sulfate results in decreased expression of TENM3 mRNA
CTD
PMID:22714537
NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594
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Terc
telomerase RNA component
decreases expression
ISO
nickel sulfate results in decreased expression of TERC mRNA
CTD
PMID:22714537
NCBI chr 2:112,815,654...112,816,041
G
Tes
testin LIM domain protein
decreases expression
ISO
nickel sulfate results in decreased expression of TES mRNA
CTD
PMID:22714537
NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829
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Tfap2c
transcription factor AP-2 gamma
increases expression
ISO
nickel sulfate results in increased expression of TFAP2C mRNA
CTD
PMID:22714537
NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
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Tfe3
transcription factor binding to IGHM enhancer 3
decreases expression
ISO
nickel sulfate results in decreased expression of TFE3 mRNA
CTD
PMID:16780908
NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571
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Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
nickel sulfate results in increased expression of TFPI2 mRNA
CTD
PMID:22714537
NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
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Tfr2
transferrin receptor 2
increases expression
ISO
nickel sulfate results in increased expression of TFR2 mRNA
CTD
PMID:17382205
NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
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Tfrc
transferrin receptor
increases expression
ISO
nickel sulfate results in increased expression of TFRC mRNA
CTD
PMID:16166746
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Tgfa
transforming growth factor alpha
affects response to substance multiple interactions
ISO EXP
TGFA protein affects the susceptibility to nickel sulfate [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of TGFA mRNA [TGFA protein binds to and affects the activity of EGFR protein] which results in decreased susceptibility to nickel sulfate; TGFA protein inhibits the reaction [nickel sulfate results in decreased expression of SFTPB protein]
CTD
PMID:11954676 PMID:19131640 PMID:31734292
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Tgfb1
transforming growth factor, beta 1
increases expression decreases expression increases secretion
ISO
nickel sulfate results in increased expression of TGFB1 mRNA nickel sulfate results in decreased expression of TGFB1 mRNA; nickel sulfate results in decreased expression of TGFB1 protein nickel sulfate results in increased secretion of TGFB1 protein
CTD
PMID:15347381 PMID:16100012 PMID:18832182 PMID:35499276
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1
transforming growth factor, beta receptor 1
decreases expression
ISO
nickel sulfate results in decreased expression of TGFBR1 mRNA
CTD
PMID:18832182 PMID:22714537
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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Tgfbr2
transforming growth factor, beta receptor 2
decreases expression
ISO
nickel sulfate results in decreased expression of TGFBR2 mRNA
CTD
PMID:22714537
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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Tgif1
TGFB-induced factor homeobox 1
increases expression
ISO
nickel sulfate results in increased expression of TGIF1 mRNA
CTD
PMID:17374397
NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
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Tgoln2
trans-golgi network protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of TGOLN2 mRNA
CTD
PMID:18651567
NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
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Thbs1
thrombospondin 1
increases expression
ISO
nickel sulfate results in increased expression of THBS1 mRNA
CTD
PMID:16100012
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
G
Thbs2
thrombospondin 2
multiple interactions increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of THBS2 mRNA nickel sulfate results in increased expression of THBS2 mRNA
CTD
PMID:18832182
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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Thnsl1
threonine synthase-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of THNSL1 mRNA
CTD
PMID:22714537
NCBI chr17:83,714,794...83,722,190
Ensembl chr17:83,714,738...83,723,805
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Thnsl2
threonine synthase-like 2
decreases expression
ISO
nickel sulfate results in decreased expression of THNSL2 mRNA
CTD
PMID:22714537
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
G
Thsd4
thrombospondin type 1 domain containing 4
decreases expression
ISO
nickel sulfate results in decreased expression of THSD4 mRNA
CTD
PMID:22714537
NCBI chr 8:60,384,636...60,984,419
Ensembl chr 8:60,386,875...61,024,995
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Thy1
Thy-1 cell surface antigen
decreases expression
ISO
nickel sulfate results in decreased expression of THY1 mRNA
CTD
PMID:22714537
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
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Tiam1
TIAM Rac1 associated GEF 1
increases expression
ISO
nickel sulfate results in increased expression of TIAM1 mRNA
CTD
PMID:16780908
NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO EXP
nickel sulfate results in increased expression of TIMP1 mRNA
CTD
PMID:11114790 PMID:16100012 PMID:16780908
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp2
TIMP metallopeptidase inhibitor 2
increases expression
ISO
nickel sulfate results in increased expression of TIMP2 mRNA
CTD
PMID:15020194
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
G
Timp3
TIMP metallopeptidase inhibitor 3
increases expression decreases expression
ISO
nickel sulfate results in increased expression of TIMP3 mRNA nickel sulfate results in decreased expression of TIMP3 mRNA
CTD
PMID:16314067 PMID:22714537
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
increases expression
ISO
nickel sulfate results in increased expression of TIPARP mRNA
CTD
PMID:18651567
NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
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Tlcd1
TLC domain containing 1
increases expression
ISO
nickel sulfate results in increased expression of TLCD1 mRNA
CTD
PMID:22714537
NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501
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Tle4
TLE family member 4, transcriptional corepressor
increases expression
ISO
nickel sulfate results in increased expression of TLE4 mRNA
CTD
PMID:22714537
NCBI chr 1:211,661,738...211,798,458
Ensembl chr 1:211,661,746...211,797,862
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Tln2
talin 2
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of TLN2 mRNA nickel sulfate results in increased expression of TLN2 mRNA
CTD
PMID:16780908
NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219
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Tlr3
toll-like receptor 3
increases expression
ISO
nickel sulfate results in increased expression of TLR3 mRNA
CTD
PMID:22714537
NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
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Tlr4
toll-like receptor 4
increases expression multiple interactions
ISO
nickel sulfate results in increased expression of TLR4 protein TLR4 protein affects the reaction [nickel sulfate results in increased expression of EBI3 mRNA]; TLR4 protein affects the reaction [nickel sulfate results in increased expression of IL27 mRNA] puerarin inhibits the reaction [nickel sulfate results in increased expression of TLR4 protein]
CTD
PMID:26607348 PMID:30421605
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tm4sf1
transmembrane 4 L six family member 1
decreases expression
ISO
nickel sulfate results in decreased expression of TM4SF1 mRNA
CTD
PMID:22714537
NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
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Tm4sf19
transmembrane 4 L six family member 19
increases expression
ISO
nickel sulfate results in increased expression of TM4SF19 mRNA
CTD
PMID:22714537
NCBI chr11:68,372,945...68,386,192
Ensembl chr11:68,371,647...68,384,591
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Tma7
translation machinery associated 7 homolog
decreases expression
ISO
nickel sulfate results in decreased expression of TMA7 mRNA
CTD
PMID:22714537
NCBI chr 8:109,726,213...109,730,902
Ensembl chr 8:109,726,196...109,735,474
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Tmcc3
transmembrane and coiled-coil domain family 3
increases expression
ISO
nickel sulfate results in increased expression of TMCC3 mRNA
CTD
PMID:16780908
NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926
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Tmem117
transmembrane protein 117
decreases expression
ISO
nickel sulfate results in decreased expression of TMEM117 mRNA
CTD
PMID:22714537
NCBI chr 7:125,757,591...126,219,692
Ensembl chr 7:125,757,591...126,219,690
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Tmem171
transmembrane protein 171
increases expression
ISO
nickel sulfate results in increased expression of TMEM171 mRNA
CTD
PMID:22714537
NCBI chr 2:30,035,278...30,045,996
Ensembl chr 2:30,035,278...30,045,049
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Tmem215
transmembrane protein 215
decreases expression
ISO
nickel sulfate results in decreased expression of TMEM215 mRNA
CTD
PMID:22714537
NCBI chr 5:55,612,568...55,615,828
Ensembl chr 5:55,612,568...55,615,828
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Tmem230
transmembrane protein 230
decreases expression
ISO
nickel sulfate results in decreased expression of TMEM230 mRNA
CTD
PMID:22714537
NCBI chr 3:119,473,109...119,497,617
Ensembl chr 3:119,480,735...119,497,614
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Tmem255a
transmembrane protein 255A
decreases expression
ISO
nickel sulfate results in decreased expression of TMEM255A mRNA
CTD
PMID:22714537
NCBI chr X:116,970,793...117,035,008
Ensembl chr X:116,970,695...117,035,008
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Tmem45a
transmembrane protein 45A
increases expression
ISO
nickel sulfate results in increased expression of TMEM45A mRNA
CTD
PMID:22714537
NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526
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Tmem52b
transmembrane protein 52B
increases expression
ISO
nickel sulfate results in increased expression of TMEM52B mRNA
CTD
PMID:22714537
NCBI chr 4:162,954,025...162,959,220
Ensembl chr 4:162,954,025...162,959,220
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Tmod1
tropomodulin 1
increases expression
ISO
nickel sulfate results in increased expression of TMOD1 mRNA
CTD
PMID:22714537
NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956
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Tmod2
tropomodulin 2
decreases expression
ISO
nickel sulfate results in decreased expression of TMOD2 mRNA
CTD
PMID:22714537
NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720
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Tmprss15
transmembrane serine protease 15
decreases expression
ISO
nickel sulfate results in decreased expression of TMPRSS15 mRNA
CTD
PMID:22714537
NCBI chr11:17,677,741...17,802,255
Ensembl chr11:17,677,741...17,802,255
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Tmsb10
thymosin, beta 10
increases expression
ISO
nickel sulfate results in increased expression of TMSB10 mRNA
CTD
PMID:18651567
NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
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Tmx4
thioredoxin-related transmembrane protein 4
decreases expression
ISO
nickel sulfate results in decreased expression of TMX4 mRNA
CTD
PMID:22714537
NCBI chr 3:121,856,237...121,899,680
Ensembl chr 3:121,856,261...121,899,641
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Tnc
tenascin C
increases expression decreases expression
ISO
nickel sulfate results in increased expression of TNC mRNA nickel sulfate results in decreased expression of TNC mRNA
CTD
PMID:16100012 PMID:22714537
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Tnf
tumor necrosis factor
decreases response to substance multiple interactions increases expression increases secretion affects expression
ISO
TNF protein results in decreased susceptibility to nickel sulfate puerarin inhibits the reaction [nickel sulfate results in increased expression of TNF protein]; Quercetin inhibits the reaction [nickel sulfate results in increased expression of TNF protein] nickel sulfate results in increased expression of TNF mRNA; nickel sulfate results in increased expression of TNF protein nickel sulfate results in increased secretion of TNF protein nickel sulfate affects the expression of TNF mRNA [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of TNF protein; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of TNF protein]; TNF protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]; TNF protein affects the reaction [nickel sulfate results in increased secretion of CXCL8 protein]; TNF protein promotes the reaction [nickel sulfate results in increased expression of CD83 protein]; U 0126 inhibits the reaction [nickel sulfate results in increased expression of TNF protein]
CTD
PMID:10929769 PMID:11893692 PMID:15679580 PMID:16099135 PMID:17118622 PMID:18495191 PMID:20385217 PMID:20417223 PMID:24964617 PMID:25673294 PMID:25957741 PMID:26607348 PMID:35499276 More...
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip2
TNF alpha induced protein 2
increases expression
ISO
nickel sulfate results in increased expression of TNFAIP2 mRNA
CTD
PMID:22714537
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
nickel sulfate results in increased expression of TNFAIP3 mRNA
CTD
PMID:16780908 PMID:18651567 PMID:20146380 PMID:20713136
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfaip6
TNF alpha induced protein 6
increases expression
ISO
nickel sulfate results in increased expression of TNFAIP6 mRNA
CTD
PMID:17374397 PMID:20713136
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
ISO
nickel sulfate results in increased expression of TNFRSF12A mRNA
CTD
PMID:16100012
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
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Tnfrsf1a
TNF receptor superfamily member 1A
affects expression
ISO
nickel sulfate affects the expression of TNFRSF1A mRNA
CTD
PMID:18202158
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tnfrsf1b
TNF receptor superfamily member 1B
increases expression
ISO
nickel sulfate results in increased expression of TNFRSF1B mRNA
CTD
PMID:16780908
NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Tnfrsf25
TNF receptor superfamily member 25
increases expression
ISO
nickel sulfate results in increased expression of TNFRSF25 mRNA
CTD
PMID:17382205
NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
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Tnfsf10
TNF superfamily member 10
decreases expression
ISO
nickel sulfate results in decreased expression of TNFSF10 mRNA
CTD
PMID:18651567
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tnfsf9
TNF superfamily member 9
increases expression
ISO
nickel sulfate results in increased expression of TNFSF9 mRNA
CTD
PMID:16166746
NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
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Tnik
TRAF2 and NCK interacting kinase
decreases expression
ISO
nickel sulfate results in decreased expression of TNIK mRNA
CTD
PMID:22714537
NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750
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Tnnt3
troponin T3, fast skeletal type
increases expression
ISO
nickel sulfate results in increased expression of TNNT3 mRNA
CTD
PMID:16166746
NCBI chr 1:197,652,535...197,669,736
Ensembl chr 1:197,652,431...197,669,535
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Tns1
tensin 1
decreases expression
ISO
nickel sulfate results in decreased expression of TNS1 mRNA
CTD
PMID:22714537
NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225
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Tob1
transducer of ErbB-2.1
increases expression
ISO
nickel sulfate results in increased expression of TOB1 mRNA
CTD
PMID:16780908
NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
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Togaram1
TOG array regulator of axonemal microtubules 1
decreases expression
ISO
nickel sulfate results in decreased expression of TOGARAM1 mRNA
CTD
PMID:16780908
NCBI chr 6:83,019,025...83,083,343
Ensembl chr 6:83,018,859...83,082,807
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Tom1
target of myb1 membrane trafficking protein
increases expression
ISO
nickel sulfate results in increased expression of TOM1 mRNA
CTD
PMID:18651567
NCBI chr19:13,405,482...13,440,384
Ensembl chr19:13,405,501...13,440,384
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Tomm34
translocase of outer mitochondrial membrane 34
increases expression
ISO
nickel sulfate results in increased expression of TOMM34 mRNA
CTD
PMID:16780908
NCBI chr 3:152,729,345...152,746,295
Ensembl chr 3:152,729,349...152,746,373
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Tox
thymocyte selection-associated high mobility group box
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of TOX mRNA nickel sulfate results in increased expression of TOX mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272
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Tp53
tumor protein p53
multiple interactions increases expression
ISO
nickel sulfate inhibits the reaction [Potassium Dichromate results in increased phosphorylation of TP53 protein] nickel sulfate results in increased expression of TP53 protein
CTD
PMID:20493934 PMID:21776270 PMID:23568779
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpbg
trophoblast glycoprotein
increases expression
ISO
nickel sulfate results in increased expression of TPBG mRNA
CTD
PMID:22714537
NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741
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Tpd52
tumor protein D52
increases expression
ISO
nickel sulfate results in increased expression of TPD52 mRNA
CTD
PMID:16780908 PMID:22714537
NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622
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Tpte2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
increases expression
ISO
nickel sulfate results in increased expression of TPTE2 mRNA
CTD
PMID:22714537
NCBI chr16:69,658,874...69,756,571
Ensembl chr16:69,658,875...69,752,949
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Traf1
TNF receptor-associated factor 1
increases expression
ISO
nickel sulfate results in increased expression of TRAF1 mRNA
CTD
PMID:16780908
NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
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Trappc2l
trafficking protein particle complex subunit 2L
increases expression
ISO
nickel sulfate results in increased expression of TRAPPC2L mRNA
CTD
PMID:22714537
NCBI chr19:50,662,507...50,666,193
Ensembl chr19:50,662,507...50,666,192
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Trim16
tripartite motif-containing 16
increases expression
ISO
nickel sulfate results in increased expression of TRIM16 mRNA
CTD
PMID:22714537
NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907
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Trim26
tripartite motif-containing 26
increases expression
ISO
nickel sulfate results in increased expression of TRIM26 mRNA
CTD
PMID:22714537
NCBI chr20:1,708,297...1,731,176
Ensembl chr20:1,709,788...1,731,120
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Trim29
tripartite motif-containing 29
increases expression
ISO
nickel sulfate results in increased expression of TRIM29 mRNA
CTD
PMID:18651567
NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992
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Trim32
tripartite motif-containing 32
decreases expression
ISO
nickel sulfate results in decreased expression of TRIM32 mRNA
CTD
PMID:16780908
NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018
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Trim33
tripartite motif-containing 33
decreases expression
ISO
nickel sulfate results in decreased expression of TRIM33 mRNA
CTD
PMID:18651567
NCBI chr 2:190,812,329...190,892,663
Ensembl chr 2:190,807,243...190,888,814
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Trim38
tripartite motif containing 38
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of TRIM38 mRNA nickel sulfate results in increased expression of TRIM38 mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr17:41,351,857...41,365,021
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Trim62
tripartite motif-containing 62
increases expression
ISO
nickel sulfate results in increased expression of TRIM62 mRNA
CTD
PMID:22714537
NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915
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Trip10
thyroid hormone receptor interactor 10
increases expression
ISO
nickel sulfate results in increased expression of TRIP10 mRNA
CTD
PMID:16780908
NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799
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Trmt6
tRNA methyltransferase 6 non-catalytic subunit
decreases expression
ISO
nickel sulfate results in decreased expression of TRMT6 mRNA
CTD
PMID:22714537
NCBI chr 3:120,074,899...120,086,639
Ensembl chr 3:120,074,911...120,086,559
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Trnt1
tRNA nucleotidyl transferase 1
decreases expression
ISO
nickel sulfate results in decreased expression of TRNT1 mRNA
CTD
PMID:22714537
NCBI chr 4:139,681,115...139,703,611
Ensembl chr 4:139,680,858...139,703,611
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Tro
trophinin
increases expression
ISO
nickel sulfate results in increased expression of TRO mRNA
CTD
PMID:22714537
NCBI chr X:19,563,395...19,574,507
Ensembl chr X:19,563,517...19,572,953
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Tsc22d3
TSC22 domain family, member 3
decreases expression
ISO
nickel sulfate results in decreased expression of TSC22D3 mRNA
CTD
PMID:25673294
NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861
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Tspan15
tetraspanin 15
increases expression
ISO
nickel sulfate results in increased expression of TSPAN15 mRNA
CTD
PMID:22714537
NCBI chr20:30,130,528...30,174,912
Ensembl chr20:30,130,530...30,174,930
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Tspan17
tetraspanin 17
increases expression
ISO
nickel sulfate results in increased expression of TSPAN17 mRNA
CTD
PMID:22714537
NCBI chr17:9,819,212...9,826,851
Ensembl chr17:9,819,202...9,826,834
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Tspan2
tetraspanin 2
decreases expression
ISO
nickel sulfate results in decreased expression of TSPAN2 mRNA
CTD
PMID:22714537
NCBI chr 2:190,177,717...190,234,994
Ensembl chr 2:190,177,741...190,219,660
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Tspan33
tetraspanin 33
increases expression
ISO
nickel sulfate results in increased expression of TSPAN33 mRNA
CTD
PMID:22714537
NCBI chr 4:58,305,378...58,330,013
Ensembl chr 4:58,305,437...58,328,940
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Tspan7
tetraspanin 7
decreases expression
ISO
nickel sulfate results in decreased expression of TSPAN7 mRNA
CTD
PMID:16780908
NCBI chr X:12,208,783...12,306,092
Ensembl chr X:12,208,783...12,306,131
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Ttc13
tetratricopeptide repeat domain 13
decreases expression
ISO
nickel sulfate results in decreased expression of TTC13 mRNA
CTD
PMID:22714537
NCBI chr19:52,637,599...52,692,196
Ensembl chr19:52,637,431...52,692,198
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Ttll7
tubulin tyrosine ligase like 7
decreases expression
ISO
nickel sulfate results in decreased expression of TTLL7 mRNA
CTD
PMID:22714537
NCBI chr 2:235,765,786...235,889,047
Ensembl chr 2:235,765,835...235,885,047
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Ttpa
alpha tocopherol transfer protein
decreases expression
ISO
nickel sulfate results in decreased expression of TTPA mRNA
CTD
PMID:22714537
NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073
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Ttyh3
tweety family member 3
increases expression
ISO
nickel sulfate results in increased expression of TTYH3 mRNA
CTD
PMID:16780908
NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
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Txn2
thioredoxin 2
increases expression
ISO
nickel sulfate results in increased expression of TXN2 mRNA
CTD
PMID:20566472
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
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Txnip
thioredoxin interacting protein
decreases expression
ISO
nickel sulfate results in decreased expression of TXNIP mRNA
CTD
PMID:22714537
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Txnrd1
thioredoxin reductase 1
affects expression increases expression
ISO
nickel sulfate affects the expression of TXNRD1 mRNA nickel sulfate results in increased expression of TXNRD1 mRNA
CTD
PMID:12718980 PMID:17374397 PMID:20566472
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Txnrd2
thioredoxin reductase 2
increases expression
ISO
nickel sulfate results in increased expression of TXNRD2 mRNA
CTD
PMID:20566472
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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Tymp
thymidine phosphorylase
decreases expression multiple interactions
ISO
nickel sulfate results in decreased expression of TYMP mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of TYMP mRNA
CTD
PMID:18832182
NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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Tyro3
TYRO3 protein tyrosine kinase
decreases expression
ISO
nickel sulfate results in decreased expression of TYRO3 mRNA
CTD
PMID:16166746
NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
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Tyrp1
tyrosinase-related protein 1
increases expression
ISO
nickel sulfate results in increased expression of TYRP1 mRNA
CTD
PMID:22714537
NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
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Ubd
ubiquitin D
increases expression
ISO
nickel sulfate results in increased expression of UBD mRNA
CTD
PMID:16780908
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Ube2e2
ubiquitin-conjugating enzyme E2E 2
decreases expression
ISO
nickel sulfate results in decreased expression of UBE2E2 mRNA
CTD
PMID:22714537
NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532
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Ube2m
ubiquitin-conjugating enzyme E2M
increases expression
ISO
nickel sulfate results in increased expression of UBE2M mRNA
CTD
PMID:18651567
NCBI chr 1:73,662,576...73,666,113
Ensembl chr 1:73,662,576...73,666,026
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Ube2s
ubiquitin-conjugating enzyme E2S
increases expression
ISO
nickel sulfate results in increased expression of UBE2S mRNA
CTD
PMID:18651567
NCBI chr 1:69,028,853...69,032,914
Ensembl chr 1:69,028,750...69,032,914
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Ubl3
ubiquitin-like 3
decreases expression
ISO
nickel sulfate results in decreased expression of UBL3 mRNA
CTD
PMID:22714537
NCBI chr12:6,473,684...6,518,331
Ensembl chr12:6,473,460...6,518,862
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Ucp1
uncoupling protein 1
multiple interactions
ISO
[nickel sulfate co-treated with Particulate Matter] results in decreased expression of UCP1 mRNA; [nickel sulfate co-treated with Particulate Matter] results in decreased expression of UCP1 protein
CTD
PMID:23126276
NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
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Uggt2
UDP-glucose glycoprotein glucosyltransferase 2
decreases expression
ISO
nickel sulfate results in decreased expression of UGGT2 mRNA
CTD
PMID:22714537
NCBI chr15:96,074,557...96,239,365
Ensembl chr15:96,074,564...96,237,806
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Ugt1a6
UDP glucuronosyltransferase family 1 member A6
increases expression
ISO
nickel sulfate results in increased expression of UGT1A6 mRNA
CTD
PMID:20566472
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ulk2
unc-51 like autophagy activating kinase 2
increases expression
ISO
nickel sulfate results in increased expression of ULK2 mRNA
CTD
PMID:22714537
NCBI chr10:46,451,578...46,530,462
Ensembl chr10:46,454,030...46,530,407
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Upp1
uridine phosphorylase 1
increases expression
ISO
nickel sulfate results in increased expression of UPP1 mRNA
CTD
PMID:18651567
NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
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Usp13
ubiquitin specific peptidase 13
decreases expression
ISO
nickel sulfate results in decreased expression of USP13 mRNA
CTD
PMID:16780908
NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222
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Usp18
ubiquitin specific peptidase 18
increases expression
ISO
nickel sulfate results in increased expression of USP18 mRNA
CTD
PMID:22714537
NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
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Usp2
ubiquitin specific peptidase 2
decreases expression
ISO
nickel sulfate results in decreased expression of USP2 mRNA
CTD
PMID:22714537
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Usp28
ubiquitin specific peptidase 28
multiple interactions decreases expression
ISO
[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in decreased expression of USP28 protein]; USP28 protein inhibits the reaction [nickel sulfate results in increased degradation of MYC protein]
CTD
PMID:20046830
NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:49,325,867...49,386,229
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Usp9x
ubiquitin specific peptidase 9, X-linked
decreases expression
ISO
nickel sulfate results in decreased expression of USP9X mRNA
CTD
PMID:22714537
NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711
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Vamp1
vesicle-associated membrane protein 1
increases expression
ISO
nickel sulfate results in increased expression of VAMP1 mRNA
CTD
PMID:22714537
NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349
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Vamp5
vesicle-associated membrane protein 5
increases expression
ISO
nickel sulfate results in increased expression of VAMP5 mRNA
CTD
PMID:22714537
NCBI chr 4:104,423,813...104,435,059
Ensembl chr 4:104,423,820...104,426,212
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Vangl2
VANGL planar cell polarity protein 2
decreases expression
ISO
nickel sulfate results in decreased expression of VANGL2 mRNA
CTD
PMID:22714537
NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378
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Vav2
vav guanine nucleotide exchange factor 2
decreases expression increases expression
ISO
nickel sulfate results in decreased expression of VAV2 mRNA nickel sulfate results in increased expression of VAV2 mRNA
CTD
PMID:16780908
NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052
G
Vbp1
VHL binding protein 1
decreases expression
ISO
nickel sulfate results in decreased expression of VBP1 mRNA
CTD
PMID:22714537
G
Vcan
versican
increases expression decreases expression
ISO
nickel sulfate results in increased expression of VCAN mRNA nickel sulfate results in decreased expression of VCAN mRNA
CTD
PMID:16166746 PMID:22714537
NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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Vdr
vitamin D receptor
increases expression
ISO
nickel sulfate results in increased expression of VDR mRNA
CTD
PMID:17374397 PMID:22714537
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
G
Vegfa
vascular endothelial growth factor A
multiple interactions increases secretion increases expression
ISO
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of VEGFA mRNA; [nickel sulfate co-treated with Dinoprostone] results in increased secretion of VEGFA protein; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of VEGFA protein]; macrophage stimulatory lipopeptide 2 promotes the reaction [nickel sulfate results in increased secretion of VEGFA protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of VEGFA protein] nickel sulfate results in increased expression of VEGFA mRNA
CTD
PMID:18832182
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfd
vascular endothelial growth factor D
increases expression
ISO
nickel sulfate results in increased expression of VEGFD mRNA
CTD
PMID:20146380
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Vit
vitrin
increases expression
ISO
nickel sulfate results in increased expression of VIT mRNA
CTD
PMID:22714537
NCBI chr 6:16,445,966...16,565,644
Ensembl chr 6:16,445,955...16,565,665
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Vldlr
very low density lipoprotein receptor
decreases expression
ISO
nickel sulfate results in decreased expression of VLDLR mRNA
CTD
PMID:22714537
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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Vtn
vitronectin
decreases expression
ISO
nickel sulfate results in decreased expression of VTN mRNA
CTD
PMID:16166746
NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
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Vwa3b
von Willebrand factor A domain containing 3B
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of VWA3B mRNA
CTD
PMID:31734292
NCBI chr 9:39,249,523...39,419,614
Ensembl chr 9:39,250,430...39,419,611
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Wipf1
WAS/WASL interacting protein family, member 1
increases expression
ISO
nickel sulfate results in increased expression of WIPF1 mRNA
CTD
PMID:22714537
NCBI chr 3:58,314,521...58,416,668
Ensembl chr 3:58,314,542...58,372,742
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Wipi1
WD repeat domain, phosphoinositide interacting 1
increases expression
ISO
nickel sulfate results in increased expression of WIPI1 mRNA
CTD
PMID:22714537
NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
G
Wnk4
WNK lysine deficient protein kinase 4
increases expression
ISO
nickel sulfate results in increased expression of WNK4 mRNA
CTD
PMID:22714537
NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
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Wnt4
Wnt family member 4
multiple interactions
EXP
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of WNT4 mRNA
CTD
PMID:31734292
NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
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Wnt5a
Wnt family member 5A
increases expression
ISO
nickel sulfate results in increased expression of WNT5A mRNA
CTD
PMID:22714537
NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
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Wtap
WT1 associated protein
decreases expression
ISO
nickel sulfate results in decreased expression of WTAP mRNA
CTD
PMID:22714537
NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065
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Wwc1
WW and C2 domain containing 1
decreases expression
ISO
nickel sulfate results in decreased expression of WWC1 mRNA
CTD
PMID:22714537
NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497
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Xaf1
XIAP associated factor 1
increases expression
ISO
nickel sulfate results in increased expression of XAF1 mRNA
CTD
PMID:22714537
NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770
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Xrn2
5'-3' exoribonuclease 2
decreases expression
ISO
nickel sulfate results in decreased expression of XRN2 mRNA
CTD
PMID:22714537
NCBI chr 3:134,436,916...134,509,308
Ensembl chr 3:134,437,109...134,509,306
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Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
increases expression
ISO
nickel sulfate results in increased expression of YWHAE mRNA
CTD
PMID:18651567
NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
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Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
increases expression
ISO
nickel sulfate results in increased expression of YWHAH mRNA
CTD
PMID:16780908
NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
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Zbtb10
zinc finger and BTB domain containing 10
increases expression
ISO
nickel sulfate results in increased expression of ZBTB10 mRNA
CTD
PMID:17382205
NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
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Zbtb16
zinc finger and BTB domain containing 16
increases expression
ISO
nickel sulfate results in increased expression of ZBTB16 mRNA
CTD
PMID:16166746
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
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Zbtb17
zinc finger and BTB domain containing 17
decreases expression
ISO
nickel sulfate results in decreased expression of ZBTB17 mRNA
CTD
PMID:17374397
NCBI chr 5:153,753,508...153,774,613
Ensembl chr 5:153,753,569...153,774,609
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Zc3h13
zinc finger CCCH type containing 13
decreases expression
ISO
nickel sulfate results in decreased expression of ZC3H13 mRNA
CTD
PMID:22714537
NCBI chr15:50,607,335...50,671,802
Ensembl chr15:50,607,380...50,671,802
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Zc3h18
zinc finger CCCH-type containing 18
increases expression
ISO
nickel sulfate results in increased expression of ZC3H18 mRNA
CTD
PMID:22714537
NCBI chr19:50,434,864...50,479,855
Ensembl chr19:50,434,903...50,479,854
G
Zc3hav1
zinc finger CCCH-type containing, antiviral 1
decreases expression
ISO
nickel sulfate results in decreased expression of ZC3HAV1 mRNA
CTD
PMID:18651567
NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
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Zc4h2
zinc finger C4H2-type containing
decreases expression
ISO
nickel sulfate results in decreased expression of ZC4H2 mRNA
CTD
PMID:22714537
NCBI chr X:60,525,706...60,546,519
Ensembl chr X:60,525,712...60,546,488
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Zcchc14
zinc finger CCHC-type containing 14
increases expression
ISO
nickel sulfate results in increased expression of ZCCHC14 mRNA
CTD
PMID:22714537
NCBI chr19:49,674,185...49,718,004
Ensembl chr19:49,674,195...49,718,029
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Zdhhc18
zinc finger DHHC-type palmitoyltransferase 18
increases expression
ISO
nickel sulfate results in increased expression of ZDHHC18 mRNA
CTD
PMID:16780908
NCBI chr 5:145,821,534...145,859,989
Ensembl chr 5:145,831,446...145,859,993
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Zdhhc21
zinc finger DHHC-type palmitoyltransferase 21
decreases expression
ISO
nickel sulfate results in decreased expression of ZDHHC21 mRNA
CTD
PMID:22714537
NCBI chr 5:97,227,621...97,286,866
Ensembl chr 5:97,229,345...97,286,537
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Zdhhc3
zinc finger DHHC-type palmitoyltransferase 3
decreases expression
ISO
nickel sulfate results in decreased expression of ZDHHC3 mRNA
CTD
PMID:16166746
NCBI chr 8:122,725,206...122,773,542
Ensembl chr 8:122,715,111...122,773,529
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Zeb1
zinc finger E-box binding homeobox 1
increases expression decreases expression
ISO
nickel sulfate results in increased expression of ZEB1 mRNA nickel sulfate results in decreased expression of ZEB1 mRNA
CTD
PMID:18651567 PMID:22714537
NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
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Zfhx4
zinc finger homeobox 4
decreases expression
ISO
nickel sulfate results in decreased expression of ZFHX4 mRNA
CTD
PMID:22714537
NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228
G
Zfp133
zinc finger protein 133
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF133 mRNA
CTD
PMID:22714537
NCBI chr 3:131,829,404...131,847,552
Ensembl chr 3:131,829,404...131,847,550
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Zfp146
zinc finger protein 146
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF146 mRNA
CTD
PMID:22714537
NCBI chr 1:85,409,570...85,421,835
Ensembl chr 1:85,409,373...85,436,275
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Zfp184
zinc finger protein 184
increases expression
ISO
nickel sulfate results in increased expression of ZNF184 mRNA
CTD
PMID:22714537
NCBI chr17:42,588,140...42,603,905
Ensembl chr17:42,566,796...42,603,815
G
Zfp239
zinc finger protein 239
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF239 mRNA
CTD
PMID:22714537
NCBI chr 4:151,029,431...151,039,283
Ensembl chr 4:151,029,405...151,039,529
G
Zfp26
zinc finger protein 26
increases expression
ISO
nickel sulfate results in increased expression of ZNF778 mRNA
CTD
PMID:22714537
NCBI chr 8:18,959,656...18,985,647
Ensembl chr 8:18,965,271...18,988,325
G
Zfp27
zinc finger protein 27
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF585A mRNA
CTD
PMID:22714537
NCBI chr 1:85,117,455...85,130,578
Ensembl chr 1:85,117,483...85,130,178
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Zfp280b
zinc finger protein 280B
increases expression
ISO
nickel sulfate results in increased expression of ZNF280B mRNA
CTD
PMID:22714537
NCBI chr20:12,627,106...12,641,943
Ensembl chr20:12,627,106...12,646,683
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Zfp287
zinc finger protein 287
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF287 mRNA
CTD
PMID:22714537
NCBI chr10:47,395,650...47,415,610
Ensembl chr10:47,397,285...47,439,755
G
Zfp334
zinc finger protein 334
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF334 mRNA
CTD
PMID:22714537
NCBI chr 3:154,112,537...154,125,087
Ensembl chr 3:154,113,561...154,125,057
G
Zfp36l1
zinc finger protein 36, C3H type-like 1
decreases expression
ISO
nickel sulfate results in decreased expression of ZFP36L1 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
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Zfp36l2
zinc finger protein 36, C3H type-like 2
increases expression
ISO
nickel sulfate results in increased expression of ZFP36L2 mRNA
CTD
PMID:18651567
NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
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Zfp382
zinc finger protein 382
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF382 mRNA
CTD
PMID:22714537
NCBI chr 1:85,377,614...85,400,832
Ensembl chr 1:85,377,484...85,399,667
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Zfp385a
zinc finger protein 385A
increases expression
ISO
nickel sulfate results in increased expression of ZNF385A mRNA
CTD
PMID:22714537
NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
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Zfp422
zinc finger protein 422
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF22 mRNA
CTD
PMID:22714537
NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257
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Zfp458
zinc finger protein 458
increases expression
ISO
nickel sulfate results in increased expression of ZNF43 mRNA
CTD
PMID:22714537
NCBI chr 2:84,661,150...84,705,631
Ensembl chr 2:84,693,186...84,702,558
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Zfp470
zinc finger protein 470
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF470 mRNA
CTD
PMID:22714537
NCBI chr 1:91,063,905...91,111,883
Ensembl chr 1:91,087,361...91,112,065
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Zfp518a
zinc finger protein 518A
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF518A mRNA
CTD
PMID:22714537
NCBI chr 1:239,719,305...239,744,978
Ensembl chr 1:239,719,505...239,744,979
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Zfp518b
zinc finger protein 518B
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF518B mRNA
CTD
PMID:22714537
NCBI chr14:72,121,085...72,140,479
Ensembl chr14:72,121,112...72,140,481
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Zfp608
zinc finger protein 608
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF608 mRNA
CTD
PMID:22714537
NCBI chr18:48,304,873...48,412,846
Ensembl chr18:48,304,880...48,410,465
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Zfp709
zinc finger protein 709
increases expression
ISO
nickel sulfate results in increased expression of ZNF443 mRNA
CTD
PMID:22714537
NCBI chr16:17,907,599...17,920,047
Ensembl chr16:17,909,641...17,919,700
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Zfp951
zinc finger protein 951
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF844 mRNA
CTD
PMID:22714537
NCBI chr14:5,032,494...5,048,775
Ensembl chr14:5,033,734...5,048,756
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Zfyve26
zinc finger FYVE-type containing 26
decreases expression
ISO
nickel sulfate results in decreased expression of ZFYVE26 mRNA
CTD
PMID:16780908 PMID:17374397
NCBI chr 6:98,031,874...98,095,538
Ensembl chr 6:98,032,520...98,095,480
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Zfyve9
zinc finger FYVE-type containing 9
decreases expression
ISO
nickel sulfate results in decreased expression of ZFYVE9 mRNA
CTD
PMID:22714537
NCBI chr 5:123,370,677...123,529,699
Ensembl chr 5:123,370,677...123,529,699
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Zg16b
zymogen granule protein 16B
increases expression
ISO
nickel sulfate results in increased expression of ZG16B mRNA
CTD
PMID:22714537
NCBI chr10:12,970,888...12,984,170
Ensembl chr10:12,979,020...12,983,572
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Zic2
Zic family member 2
increases expression
ISO
nickel sulfate results in increased expression of ZIC2 mRNA
CTD
PMID:22714537
NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522
G
Zmym2
zinc finger MYM-type containing 2
decreases expression
ISO
nickel sulfate results in decreased expression of ZMYM2 mRNA
CTD
PMID:22714537
NCBI chr15:31,035,835...31,108,945
Ensembl chr15:31,035,838...31,109,357
G
Zmym3
zinc finger MYM-type containing 3
decreases expression multiple interactions
ISO EXP
nickel sulfate results in decreased expression of ZMYM3 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ZMYM3 mRNA
CTD
PMID:17374397 PMID:31734292
NCBI chr X:66,528,585...66,544,234
Ensembl chr X:66,528,585...66,544,782
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Znf660
zinc finger protein 660
decreases expression
ISO
nickel sulfate results in decreased expression of ZNF660 mRNA
CTD
PMID:22714537
NCBI chr 8:122,523,881...122,537,581
Ensembl chr 8:122,524,324...122,536,247
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