Rbck1 (RANBP2-type and C3HC4-type zinc finger containing 1) - Rat Genome Database

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Gene: Rbck1 (RANBP2-type and C3HC4-type zinc finger containing 1) Rattus norvegicus
Analyze
Symbol: Rbck1
Name: RANBP2-type and C3HC4-type zinc finger containing 1
RGD ID: 708404
Description: Enables double-stranded DNA binding activity and protein kinase C binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of LUBAC complex. Human ortholog(s) of this gene implicated in glycogen storage disease. Orthologous to human RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; allethrin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: heme-oxidized IRP2 ubiquitin ligase 1 homolog; HOIL-1; LOC60383; Pkcbpb15; protein kinase C-binding protein beta-15; protein kinase C-binding protein Beta15; RanBP-type and C3HC4-type zinc finger containing 1; ranBP-type and C3HC4-type zinc finger-containing protein 1; RBCC protein interacting with PKC 1; RING-type E3 ubiquitin transferase HOIL-1; ubiquitin-conjugating enzyme 7-interacting protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,249,389 - 161,266,321 (-)NCBIGRCr8
mRatBN7.23140,789,079 - 140,806,017 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,789,080 - 140,806,005 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3144,693,960 - 144,710,813 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,277,793 - 153,294,653 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,018,228 - 151,034,882 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,793,014 - 147,809,941 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,793,017 - 147,809,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,141,154 - 154,158,071 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,644,156 - 142,660,799 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13142,549,729 - 142,566,372 (-)NCBI
Celera3139,541,427 - 139,557,526 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
LUBAC complex  (IBA,IEA,ISO,ISS)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Tumor necrosis factor. Chu WM, Cancer Lett. 2013 Jan 28;328(2):222-5. doi: 10.1016/j.canlet.2012.10.014. Epub 2012 Oct 22.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
6. Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins. Tokunaga C, etal., Biochem Biophys Res Commun 1998 Mar 17;244(2):353-9.
7. Molecular cloning and characterization of RBCK2, a splicing variant of a RBCC family protein, RBCK1. Tokunaga C, etal., FEBS Lett 1998 Sep 11;435(1):11-5.
8. Accumulation of polyubiquitinated proteins by overexpression of RBCC protein interacting with protein kinase C2, a splice variant of ubiquitin ligase RBCC protein interacting with protein kinase C1. Yoshimoto N, etal., FEBS J. 2009 Nov;276(21):6375-85. doi: 10.1111/j.1742-4658.2009.07350.x. Epub 2009 Oct 1.
Additional References at PubMed
PMID:12629548   PMID:15833741   PMID:17006537   PMID:17121852   PMID:17449468   PMID:19028597   PMID:19136968   PMID:20005846   PMID:21455173   PMID:21455180   PMID:21455181   PMID:22089168  
PMID:23453807   PMID:24726323   PMID:25416956   PMID:27523608   PMID:30561431  


Genomics

Comparative Map Data
Rbck1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,249,389 - 161,266,321 (-)NCBIGRCr8
mRatBN7.23140,789,079 - 140,806,017 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,789,080 - 140,806,005 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3144,693,960 - 144,710,813 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,277,793 - 153,294,653 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,018,228 - 151,034,882 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,793,014 - 147,809,941 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,793,017 - 147,809,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,141,154 - 154,158,071 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,644,156 - 142,660,799 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13142,549,729 - 142,566,372 (-)NCBI
Celera3139,541,427 - 139,557,526 (-)NCBICelera
Cytogenetic Map3q41NCBI
RBCK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820408,299 - 432,139 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl20407,498 - 432,139 (+)EnsemblGRCh38hg38GRCh38
GRCh3720388,943 - 412,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3620336,709 - 359,610 (+)NCBINCBI36Build 36hg18NCBI36
Build 3420336,755 - 359,610NCBI
Celera20483,557 - 506,462 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef20340,142 - 362,963 (+)NCBIHuRef
CHM1_120388,711 - 411,612 (+)NCBICHM1_1
T2T-CHM13v2.020451,838 - 475,908 (+)NCBIT2T-CHM13v2.0
Rbck1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,158,254 - 152,174,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2152,158,254 - 152,174,573 (-)EnsemblGRCm39 Ensembl
GRCm382152,316,334 - 152,332,663 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,316,334 - 152,332,653 (-)EnsemblGRCm38mm10GRCm38
MGSCv372152,142,070 - 152,158,375 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,007,778 - 152,024,076 (-)NCBIMGSCv36mm8
Celera2158,130,477 - 158,146,782 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
Rbck1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955597271,897 - 289,348 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955597272,352 - 289,348 (+)NCBIChiLan1.0ChiLan1.0
RBCK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2211,496,107 - 1,519,662 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1201,493,162 - 1,516,494 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v020615,987 - 639,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.120386,569 - 409,587 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl20386,569 - 409,580 (+)Ensemblpanpan1.1panPan2
RBCK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,423,378 - 20,440,985 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,423,988 - 20,441,114 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,077,323 - 20,094,821 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,116,652 - 21,134,123 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,116,180 - 21,134,273 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,391,937 - 20,409,382 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,497,899 - 20,515,382 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02420,928,435 - 20,945,897 (-)NCBIUU_Cfam_GSD_1.0
Rbck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640169,626,204 - 169,641,220 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648518,057,534 - 18,071,816 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648518,057,569 - 18,071,787 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBCK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,784,016 - 34,801,230 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,784,018 - 34,801,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,566,871 - 39,579,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103247827
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1235,537,387 - 35,559,628 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl235,538,127 - 35,560,129 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660787,711,829 - 7,726,135 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbck1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247411,502,942 - 1,523,675 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247411,503,017 - 1,523,542 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbck1
82 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:332
Count of miRNA genes:198
Interacting mature miRNAs:240
Transcripts:ENSRNOT00000045314
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3140069424146976080Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat

Markers in Region
BE109253  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23140,802,339 - 140,802,509 (+)MAPPERmRatBN7.2
Rnor_6.03147,806,273 - 147,806,442NCBIRnor6.0
Rnor_5.03154,154,414 - 154,154,583UniSTSRnor5.0
RGSC_v3.43142,657,415 - 142,657,584UniSTSRGSC3.4
RH 3.4 Map31271.3UniSTS
Cytogenetic Map3q41UniSTS
AU048771  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23140,797,885 - 140,798,142 (+)MAPPERmRatBN7.2
Rnor_6.03147,801,822 - 147,802,076NCBIRnor6.0
Rnor_5.03154,149,963 - 154,150,217UniSTSRnor5.0
RGSC_v3.43142,652,963 - 142,653,217UniSTSRGSC3.4
Celera3139,550,233 - 139,550,487UniSTS
Cytogenetic Map3q41UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000045314   ⟹   ENSRNOP00000047637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3140,789,081 - 140,805,726 (-)Ensembl
Rnor_6.0 Ensembl3147,793,017 - 147,809,658 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085849   ⟹   ENSRNOP00000075043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3140,789,080 - 140,806,005 (-)Ensembl
Rnor_6.0 Ensembl3147,793,329 - 147,809,919 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085995   ⟹   ENSRNOP00000072645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3140,789,080 - 140,805,722 (-)Ensembl
Rnor_6.0 Ensembl3147,793,017 - 147,809,658 (-)Ensembl
RefSeq Acc Id: NM_021764   ⟹   NP_068532
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,249,389 - 161,266,032 (-)NCBI
mRatBN7.23140,789,080 - 140,805,726 (-)NCBI
Rnor_6.03147,793,016 - 147,809,658 (-)NCBI
Rnor_5.03154,141,154 - 154,158,071 (-)NCBI
RGSC_v3.43142,644,156 - 142,660,799 (-)RGD
Celera3139,541,427 - 139,557,526 (-)RGD
Sequence:
RefSeq Acc Id: XM_006235252   ⟹   XP_006235314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,249,389 - 161,266,321 (-)NCBI
mRatBN7.23140,789,080 - 140,806,017 (-)NCBI
Rnor_6.03147,793,014 - 147,809,941 (-)NCBI
Rnor_5.03154,141,154 - 154,158,071 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105766   ⟹   XP_038961694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,256,262 - 161,266,112 (-)NCBI
mRatBN7.23140,796,076 - 140,805,781 (-)NCBI
RefSeq Acc Id: XM_063284455   ⟹   XP_063140525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,249,389 - 161,266,319 (-)NCBI
RefSeq Acc Id: XM_063284456   ⟹   XP_063140526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,249,389 - 161,259,307 (-)NCBI
RefSeq Acc Id: XM_063284457   ⟹   XP_063140527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83161,252,283 - 161,266,112 (-)NCBI
RefSeq Acc Id: NP_068532   ⟸   NM_021764
- UniProtKB: Q9QWN4 (UniProtKB/Swiss-Prot),   Q9Z334 (UniProtKB/Swiss-Prot),   Q62921 (UniProtKB/Swiss-Prot),   A0A0G2K3H9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235314   ⟸   XM_006235252
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K9L6 (UniProtKB/TrEMBL),   A6KHM8 (UniProtKB/TrEMBL),   A0A0G2K3H9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047637   ⟸   ENSRNOT00000045314
Ensembl Acc Id: ENSRNOP00000072645   ⟸   ENSRNOT00000085995
Ensembl Acc Id: ENSRNOP00000075043   ⟸   ENSRNOT00000085849
RefSeq Acc Id: XP_038961694   ⟸   XM_039105766
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063140525   ⟸   XM_063284455
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K3H9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140526   ⟸   XM_063284456
- Peptide Label: isoform X3
- UniProtKB: A6KHM9 (UniProtKB/TrEMBL),   D4A367 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140527   ⟸   XM_063284457
- Peptide Label: isoform X4
Protein Domains
RanBP2-type   RING-type   Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62921-F1-model_v2 AlphaFold Q62921 1-508 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692537
Promoter ID:EPDNEW_R3058
Type:initiation region
Name:Rbck1_1
Description:RANBP2-type and C3HC4-type zinc finger containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3059  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03147,809,587 - 147,809,647EPDNEW
RGD ID:13692542
Promoter ID:EPDNEW_R3059
Type:initiation region
Name:Rbck1_2
Description:RANBP2-type and C3HC4-type zinc finger containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3058  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03147,809,909 - 147,809,969EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708404 AgrOrtholog
BioCyc Gene G2FUF-47275 BioCyc
Ensembl Genes ENSRNOG00000006695 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045314.4 UniProtKB/TrEMBL
  ENSRNOT00000085849.2 UniProtKB/TrEMBL
  ENSRNOT00000085995.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1750 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zn-finger domain of Sec23/24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598480 IMAGE-MGC_LOAD
InterPro BRcat_RBR_HOIL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOIL1_RBR_mRING-HC-C3HC3D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rcat_RBR_HOIL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
  Znf-RING_LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:60383 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72463 IMAGE-MGC_LOAD
NCBI Gene 60383 ENTREZGENE
PANTHER PTHR22770:SF35 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-RING_UBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbck1 PhenoGen
PROSITE TRIAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006695 RatGTEx
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90209 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K3H9 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K9L6 ENTREZGENE, UniProtKB/TrEMBL
  A6KHM8 ENTREZGENE, UniProtKB/TrEMBL
  A6KHM9 ENTREZGENE, UniProtKB/TrEMBL
  D4A367 ENTREZGENE, UniProtKB/TrEMBL
  HOIL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P7C9_RAT UniProtKB/TrEMBL
  Q9QWN4 ENTREZGENE
  Q9Z334 ENTREZGENE
UniProt Secondary Q9QWN4 UniProtKB/Swiss-Prot
  Q9Z334 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Rbck1  RANBP2-type and C3HC4-type zinc finger containing 1  Rbck1  RanBP-type and C3HC4-type zinc finger containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Rbck1  RanBP-type and C3HC4-type zinc finger containing 1  Pkcbpb15  protein kinase C-binding protein Beta15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Pkcbpb15  protein kinase C-binding protein Beta15  LOC60383    Symbol updated 1299863 APPROVED