RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1) - Rat Genome Database

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Gene: RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1) Sus scrofa
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Symbol: RBCK1
Name: RANBP2-type and C3HC4-type zinc finger containing 1
RGD ID: 14263704
Description: ENCODES a protein that exhibits double-stranded DNA binding (ortholog); protein kinase C binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN cytoplasmic sequestering of protein (ortholog); negative regulation of necroptotic process (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); glycogen storage disease IV (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN LUBAC complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ranBP-type and C3HC4-type zinc finger-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,784,016 - 34,801,231 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,784,018 - 34,801,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,566,871 - 39,579,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
RBCK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,784,016 - 34,801,231 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,784,018 - 34,801,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,566,871 - 39,579,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RBCK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl20407,498 - 432,139 (+)EnsemblGRCh38hg38GRCh38
GRCh3820408,299 - 432,139 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3720388,943 - 412,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3620336,709 - 359,610 (+)NCBINCBI36hg18NCBI36
Build 3420336,755 - 359,610NCBI
Celera20483,557 - 506,462 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef20340,142 - 362,963 (+)NCBIHuRef
CHM1_120388,711 - 411,612 (+)NCBICHM1_1
Rbck1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,158,254 - 152,174,583 (-)NCBIGRCm39mm39
GRCm39 Ensembl2152,158,254 - 152,174,573 (-)Ensembl
GRCm382152,316,334 - 152,332,663 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,316,334 - 152,332,653 (-)EnsemblGRCm38mm10GRCm38
MGSCv372152,142,070 - 152,158,375 (-)NCBIGRCm37mm9NCBIm37
MGSCv362152,007,778 - 152,024,076 (-)NCBImm8
Celera2158,130,477 - 158,146,782 (-)NCBICelera
Cytogenetic Map2G3NCBI
Rbck1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23140,789,079 - 140,806,017 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3140,789,080 - 140,806,005 (-)Ensembl
Rnor_6.03147,793,014 - 147,809,941 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,793,017 - 147,809,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,141,154 - 154,158,071 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,644,156 - 142,660,799 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13142,549,729 - 142,566,372 (-)NCBI
Celera3139,541,427 - 139,557,526 (-)NCBICelera
Cytogenetic Map3q41NCBI
Rbck1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955597271,897 - 289,348 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955597272,352 - 289,348 (+)NCBIChiLan1.0ChiLan1.0
RBCK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.120386,569 - 409,587 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl20386,569 - 409,580 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v020615,987 - 639,366 (+)NCBIMhudiblu_PPA_v0panPan3
RBCK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,423,378 - 20,440,985 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,423,988 - 20,441,114 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,077,323 - 20,094,821 (-)NCBI
ROS_Cfam_1.02421,116,652 - 21,134,123 (-)NCBI
ROS_Cfam_1.0 Ensembl2421,116,180 - 21,134,273 (-)Ensembl
UMICH_Zoey_3.12420,391,937 - 20,409,382 (-)NCBI
UNSW_CanFamBas_1.02420,497,899 - 20,515,382 (-)NCBI
UU_Cfam_GSD_1.02420,928,435 - 20,945,897 (-)NCBI
Rbck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640169,626,204 - 169,641,220 (-)NCBI
SpeTri2.0NW_00493648518,057,569 - 18,071,787 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103247827
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1235,537,387 - 35,559,628 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl235,538,127 - 35,560,129 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660787,711,829 - 7,726,135 (+)NCBIVero_WHO_p1.0
Rbck1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247411,503,017 - 1,523,542 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007885   ⟹   ENSSSCP00000007674
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1734,784,016 - 34,801,231 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000061567   ⟹   ENSSSCP00000055645
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1734,784,016 - 34,800,529 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000063860   ⟹   ENSSSCP00000049147
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1734,784,018 - 34,801,172 (-)Ensembl
RefSeq Acc Id: XM_021078286   ⟹   XP_020933945
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11734,784,018 - 34,801,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078287   ⟹   XP_020933946
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11734,784,022 - 34,801,224 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020933945 (Get FASTA)   NCBI Sequence Viewer  
  XP_020933946 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020933945   ⟸   XM_021078286
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020933946   ⟸   XM_021078287
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000055645   ⟸   ENSSSCT00000061567
RefSeq Acc Id: ENSSSCP00000007674   ⟸   ENSSSCT00000007885
RefSeq Acc Id: ENSSSCP00000049147   ⟸   ENSSSCT00000063860
Protein Domains
RanBP2-type   RING-type   Ubiquitin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007206 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070002736 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000007674 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000049147 UniProtKB/TrEMBL
  ENSSSCP00000055645 UniProtKB/TrEMBL
  ENSSSCP00070004201 UniProtKB/TrEMBL
  ENSSSCP00070004210 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007885 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000061567 UniProtKB/TrEMBL
  ENSSSCT00000063860 UniProtKB/TrEMBL
  ENSSSCT00070005167 UniProtKB/TrEMBL
  ENSSSCT00070005177 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro IBR_dom UniProtKB/TrEMBL
  RBCK1/SHARPIN UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene RBCK1 ENTREZGENE
PANTHER PTHR22770:SF35 UniProtKB/TrEMBL
Pfam IBR UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PROSITE TRIAD UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  SSF90209 UniProtKB/TrEMBL
UniProt A0A287AZ52_PIG UniProtKB/TrEMBL
  A0A287BGD0_PIG UniProtKB/TrEMBL
  A0A4X1SNP7_PIG UniProtKB/TrEMBL
  A0A4X1SQ32_PIG UniProtKB/TrEMBL
  F1S7J3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:98284 ENTREZGENE