Gene: Lifr (LIF receptor alpha) Rattus norvegicus
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Symbol: Lifr
Name: LIF receptor alpha
Description: ENCODES a protein that exhibits cytokine binding; leukemia inhibitory factor receptor activity; ciliary neurotrophic factor receptor activity (ortholog); INVOLVED IN animal organ regeneration; negative regulation of muscle cell apoptotic process; neuron projection morphogenesis; PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH Left Ventricular Hypertrophy; CAKUT (ortholog); hepatocellular carcinoma (ortholog); FOUND IN receptor complex (ortholog); INTERACTS WITH 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leukemia inhibitor factor receptor alpha-chain; leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha; LIF receptor; LIF-R
Orthologs:
Homo sapiens (human) : LIFR (LIF receptor alpha)  HGNC  Alliance
Mus musculus (house mouse) : Lifr (LIF receptor alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lifr (LIF receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : LIFR (LIF receptor alpha)
Canis lupus familiaris (dog) : LIFR (LIF receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lifr (LIF receptor alpha)
Sus scrofa (pig) : LOC102167255 (leukemia inhibitory factor receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0256,424,910 - 56,489,346 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0276,165,154 - 76,229,631 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4256,426,058 - 56,477,198 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1256,354,290 - 56,405,431 (+)NCBI
Celera251,855,443 - 51,906,055 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lifr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621431
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE