Fetub (fetuin B) - Rat Genome Database

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Gene: Fetub (fetuin B) Rattus norvegicus
Analyze
Symbol: Fetub
Name: fetuin B
RGD ID: 69293
Description: Predicted to have metalloendopeptidase inhibitor activity. Predicted to be involved in binding activity of sperm to zona pellucida and negative regulation of endopeptidase activity. Predicted to localize to extracellular region. Orthologous to human FETUB (fetuin B); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Fet; Fet_mapped; Fetuin (phosphoprotein, 63 kDa); fetuin beta; fetuin phosphoprotein; fetuin phosphoprotein (mapped); fetuin-B; fetuin-like protein IRL685; IRL685; Pp63
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21178,082,158 - 78,093,022 (-)NCBI
Rnor_6.0 Ensembl1181,648,885 - 81,660,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01181,648,890 - 81,660,472 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,745,605 - 84,758,630 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,276,852 - 80,285,039 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,334,442 - 80,342,628 (-)NCBI
Celera1176,955,006 - 76,965,868 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1300185   PMID:12676929   PMID:23533145   PMID:23562279  


Genomics

Comparative Map Data
Fetub
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21178,082,158 - 78,093,022 (-)NCBI
Rnor_6.0 Ensembl1181,648,885 - 81,660,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01181,648,890 - 81,660,472 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,745,605 - 84,758,630 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,276,852 - 80,285,039 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,334,442 - 80,342,628 (-)NCBI
Celera1176,955,006 - 76,965,868 (-)NCBICelera
Cytogenetic Map11q23NCBI
FETUB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3186,635,969 - 186,653,141 (+)EnsemblGRCh38hg38GRCh38
GRCh383186,635,969 - 186,653,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373186,353,758 - 186,370,930 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,840,843 - 187,853,491 (+)NCBINCBI36hg18NCBI36
Build 343187,840,850 - 187,853,498NCBI
Celera3184,794,517 - 184,807,165 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,767,693 - 183,780,343 (+)NCBIHuRef
CHM1_13186,322,116 - 186,334,762 (+)NCBICHM1_1
Fetub
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,737,132 - 22,758,518 (+)NCBIGRCm39mm39
GRCm39 Ensembl1622,737,084 - 22,758,528 (+)Ensembl
GRCm381622,918,382 - 22,939,768 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,918,334 - 22,939,778 (+)EnsemblGRCm38mm10GRCm38
MGSCv371622,918,455 - 22,939,841 (+)NCBIGRCm37mm9NCBIm37
MGSCv361622,835,635 - 22,855,086 (+)NCBImm8
Celera1623,478,707 - 23,499,723 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.76NCBI
Fetub
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542021,040,621 - 21,054,391 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542021,041,419 - 21,054,043 (-)NCBIChiLan1.0ChiLan1.0
FETUB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13192,142,595 - 192,155,297 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,142,702 - 192,154,920 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03183,675,258 - 183,687,754 (+)NCBIMhudiblu_PPA_v0panPan3
FETUB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,259,362 - 19,273,030 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,259,357 - 19,273,030 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,344,736 - 23,358,404 (+)NCBI
ROS_Cfam_1.03419,170,300 - 19,183,973 (+)NCBI
UMICH_Zoey_3.13419,202,641 - 19,216,289 (+)NCBI
UNSW_CanFamBas_1.03419,202,473 - 19,216,130 (+)NCBI
UU_Cfam_GSD_1.03419,430,947 - 19,444,615 (+)NCBI
Fetub
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,210,109 - 117,225,168 (-)NCBI
SpeTri2.0NW_0049365783,302,005 - 3,310,536 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FETUB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,460,272 - 124,494,196 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,480,456 - 124,494,197 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,870,414 - 133,884,133 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FETUB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,773,057 - 2,790,944 (-)NCBI
ChlSab1.1 Ensembl152,770,927 - 2,790,248 (-)Ensembl
Fetub
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473070,092,056 - 70,112,025 (-)NCBI

Position Markers
RH134374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,082,203 - 78,082,406 (+)MAPPER
Rnor_6.01181,648,936 - 81,649,138NCBIRnor6.0
Rnor_5.01184,745,651 - 84,745,853UniSTSRnor5.0
RGSC_v3.41180,276,898 - 80,277,100UniSTSRGSC3.4
Celera1176,955,052 - 76,955,254UniSTS
RH 3.4 Map11649.9UniSTS
Cytogenetic Map11q23UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111901627290463843Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112831466586994795Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)113043533986714631Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113215552082443118Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114309033886714631Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114658320986714631Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114726402386994547Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114726402386994547Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115785881090463843Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115994302390463843Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116010984287141948Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)116265336586714475Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116265336586714483Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116449467190463843Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116934231986312439Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116964970890463843Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117272002986994795Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)118035840887200449Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:193
Count of miRNA genes:105
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000046199, ENSRNOT00000048739
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 27 27 21
Medium 20 18 18 8 2 11
Low 3 16 2 19 2 4 4 10 17 27 4
Below cutoff 1 13 4 5 18 8 7 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001309522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ242926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW395163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000048739   ⟹   ENSRNOP00000051504
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1181,648,885 - 81,660,395 (-)Ensembl
RefSeq Acc Id: NM_001309522   ⟹   NP_001296451
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21178,082,174 - 78,093,022 (-)NCBI
Rnor_6.01181,648,906 - 81,660,472 (-)NCBI
Celera1176,955,022 - 76,965,868 (-)NCBI
Sequence:
RefSeq Acc Id: NM_053348   ⟹   NP_445800
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21178,082,158 - 78,090,380 (-)NCBI
Rnor_6.01181,648,890 - 81,657,471 (-)NCBI
Rnor_5.01184,745,605 - 84,758,630 (-)NCBI
RGSC_v3.41180,276,852 - 80,285,039 (-)RGD
Celera1176,955,006 - 76,963,228 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_445800   ⟸   NM_053348
- Peptide Label: precursor
- UniProtKB: Q9QX79 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001296451   ⟸   NM_001309522
- Peptide Label: isoform 1 precursor
- UniProtKB: Q6IRS6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000051504   ⟸   ENSRNOT00000048739
Protein Domains
Cystatin fetuin-B-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698249
Promoter ID:EPDNEW_R8774
Type:initiation region
Name:Fetub_1
Description:fetuin B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01181,660,207 - 81,660,267EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69293 AgrOrtholog
Ensembl Genes ENSRNOG00000001806 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000051504 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048739 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7099154 IMAGE-MGC_LOAD
InterPro Cystatin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cystatin_Fetuin_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_inh_fetuin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83928 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91528 IMAGE-MGC_LOAD
NCBI Gene 83928 ENTREZGENE
Pfam Cystatin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fetub PhenoGen
PROSITE CYSTATIN_FETUIN_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FETUIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FETUIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00043 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218955
UniProt FETUB_RAT UniProtKB/Swiss-Prot
  Q6IRS6 ENTREZGENE, UniProtKB/TrEMBL
  Q9QX79 ENTREZGENE
UniProt Secondary F1LN83 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Fetub  fetuin B  Fetub  fetuin beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-10-15 Fetub  fetuin beta  Fet_mapped  fetuin phosphoprotein (mapped)  Data Merged 737654 APPROVED
2005-11-17 Fet_mapped  fetuin phosphoprotein (mapped)  Fet  Fetuin (phosphoprotein, 63 kDa)  Symbol and Name updated 1556543 APPROVED
2002-06-10 Fet  Fetuin (phosphoprotein, 63 kDa)      Symbol and Name status set to approved 70586 APPROVED
2002-06-10 Fetub  fetuin beta      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction forms a fetuin-mineral complex with calcium phosphate and matrix Gla protein in vitro 1300185
gene_regulation down-regulated during experimentally induced inflammation 68778