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Gene: Lmbr1 (limb development membrane protein 1) Rattus norvegicus
Symbol: Lmbr1
Name: limb development membrane protein 1
RGD ID: 1563910
Description: Predicted to have transmembrane signaling receptor activity. Predicted to be involved in embryonic digit morphogenesis and signal transduction. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in Laurin-Sandrow syndrome; acheiropody; hypoplastic or aplastic tibia with polydactyly; and syndactyly type 4. Orthologous to human LMBR1 (limb development membrane protein 1); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; ketamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: limb region 1; limb region 1 homolog; limb region 1 homolog (mouse); limb region 1 protein homolog; LOC362295; RGD1563910; similar to Lmbr1 protein
Homo sapiens (human) : LMBR1 (limb development membrane protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Lmbr1 (limb region 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lmbr1 (limb development membrane protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LMBR1 (limb development membrane protein 1)
Canis lupus familiaris (dog) : LMBR1 (limb development membrane protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmbr1 (limb development membrane protein 1)
Sus scrofa (pig) : LMBR1 (limb development membrane protein 1)
Chlorocebus sabaeus (African green monkey) : LMBR1 (limb development membrane protein 1)
Heterocephalus glaber (naked mole-rat) : Lmbr1 (limb development membrane protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.042,116,094 - 2,274,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl42,116,094 - 2,201,749 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.042,172,459 - 2,330,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.441,177,941 - 1,344,583 (+)NCBIRGSC3.4rn4RGSC3.4
Celera44,186,584 - 4,352,183 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Lmbr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563910
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.