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Gene: Vbp1 (VHL binding protein 1) Rattus norvegicus

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Symbol:

Vbp1

Name:

VHL binding protein 1

RGD ID:

1590535

Description:

Orthologous to human VBP1 (VHL binding protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC681825; prefoldin subunit 3; similar to Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1); von Hippel-Lindau binding protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VBP1 (VHL binding protein 1)	HGNC	Ensembl, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Vbp1 (von Hippel-Lindau binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Vbp1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VBP1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	VBP1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vbp1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VBP1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	VBP1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Vbp1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Vbp1 (VHL binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	VBP1 (VHL binding protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	VBP1 (VHL binding protein 1)	Alliance	DIOPT (HGNC)
Mus musculus (house mouse):	Vbp1 (von Hippel-Lindau binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	vbp1 (von Hippel-Lindau binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PAC10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pfd-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	mgr	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	vbp1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Related Pseudogenes:

Vbp1l-ps1

Latest Assembly:

GRCr8 - GRCr8 Assembly

NCBI Annotation Information:

Genome Annotation Status: not in current annotation release

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
UTH_Rnor_SHR_Utx	Y	2,110,980 - 2,128,847 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	158,486,589 - 158,504,456 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	Y	278,442 - 296,310 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	148,425,046 - 148,443,505 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	148,424,977 - 148,443,358 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	154,704,249 - 154,723,093 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	1	137,517,154 - 137,532,514 (-)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Ependymomas (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aconitine (EXP)

aflatoxin M1 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bezafibrate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

clofibrate (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

homocysteine (ISO)

ivermectin (ISO)

L-methionine (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel sulfate (ISO)

paracetamol (EXP)

perfluorohexanesulfonic acid (ISO)

permethrin (EXP)

potassium chromate (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

toluene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of amyloid fibril formation (ISO)

protein folding (ISO)

Cellular Component

cytosol (ISO)

prefoldin complex (ISO)

Molecular Function

amyloid-beta binding (ISO)

protein binding (ISO)

unfolded protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:31505169

Genomics

Comparative Map Data

Vbp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
UTH_Rnor_SHR_Utx	Y	2,110,980 - 2,128,847 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	158,486,589 - 158,504,456 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	Y	278,442 - 296,310 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	148,425,046 - 148,443,505 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	148,424,977 - 148,443,358 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	154,704,249 - 154,723,093 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	1	137,517,154 - 137,532,514 (-)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

VBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	155,197,007 - 155,239,841 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	155,197,007 - 155,239,841 (+)	Ensembl			hg38	GRCh38
GRCh37	X	154,425,284 - 154,468,122 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	154,097,744 - 154,121,292 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	154,008,253 - 154,031,800	NCBI
Celera	X	154,603,029 - 154,626,576 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	142,988,694 - 143,012,102 (+)	NCBI		HuRef
CHM1_1	X	154,356,371 - 154,379,765 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	153,433,306 - 153,476,144 (+)	NCBI		T2T-CHM13v2.0

Vbp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	74,557,903 - 74,578,552 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	74,557,905 - 74,578,548 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	75,514,297 - 75,534,946 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	75,514,299 - 75,534,942 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	72,759,636 - 72,780,285 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	71,767,074 - 71,787,619 (+)	NCBI		MGSCv36	mm8
Celera	X	66,916,302 - 66,937,018 (+)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	38.25	NCBI

Vbp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955594	447,750 - 477,796 (-)	Ensembl
ChiLan1.0	NW_004955594	450,048 - 477,504 (-)	NCBI	ChiLan1.0	ChiLan1.0

VBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	155,184,268 - 155,208,081 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	155,187,876 - 155,211,689 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	144,685,548 - 144,709,136 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	154,504,795 - 154,547,773 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	154,504,795 - 154,547,773 (+)	Ensembl			panPan2	panpan1.1

VBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	123,210,965 - 123,231,847 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	123,203,722 - 123,231,091 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	108,198,258 - 108,219,138 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	126,332,496 - 126,353,396 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	126,325,242 - 126,353,392 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	122,080,310 - 122,101,180 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	124,602,728 - 124,623,602 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	124,323,269 - 124,343,955 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Vbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	120,075,121 - 120,109,719 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936927	433,551 - 469,331 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936927	433,598 - 468,191 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	125,480,808 - 125,506,771 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	125,485,357 - 125,506,781 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	142,924,188 - 142,945,608 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VBP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	129,487,543 - 129,510,301 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666065	67,467,011 - 67,489,809 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vbp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624963	93,135 - 129,198 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624963	94,482 - 129,223 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Vbp1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	273,297 - 295,485 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	30
Count of miRNA genes:	28
Interacting mature miRNAs:	29
Transcripts:	ENSRNOT00000072973
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

RH143849

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	148,427,958 - 148,428,409	NCBI	Rnor6.0
Rnor_5.0	1	154,707,153 - 154,707,604	UniSTS	Rnor5.0
Celera	1	137,519,575 - 137,520,026	UniSTS

RH144452

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	148,444,309 - 148,444,519	NCBI	Rnor6.0
Rnor_5.0	1	154,723,847 - 154,724,057	UniSTS	Rnor5.0
Celera	1	137,533,482 - 137,533,692	UniSTS

BE100112

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	148,427,003 - 148,427,164	NCBI	Rnor6.0
Rnor_5.0	1	154,706,198 - 154,706,359	UniSTS	Rnor5.0
Celera	1	137,518,620 - 137,518,781	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001398700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001058594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	FQ233397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072973 ⟹ ENSRNOP00000065979

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	148,424,977 - 148,443,358 (-)	Ensembl

RefSeq Acc Id:

XM_001058594 ⟹ XP_001058594

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Celera	1	137,517,154 - 137,532,514 (-)	NCBI

Sequence:

show sequence

TCGCTCCGCCTCCTTCCCAAGATGGCGGCGGCTCAGGGAGGGCGCGGCTTGGAGGCGGGCAACG
GTCGGCGGCTGCACCTGGGGATTCCAGAAGCGGTGTTCGTGGAGGATGTGGACGCCTTCATGGC
GCAGCCCGGAAATGAGAGCGCAGACGCCGCGCTGCGGAAGCTGGACGAGCGCTACCAGAAATAC
AAGTTCATGGAGCTCAGCCTCGCACAGCGCAAGCGCAGGCTGAAGTCGCAGATCCCTGAGATCA
AGCAGACGCTGGAGATCCTCAAATACATGCAGCGGAAGAAGGGGTCGCCCCACGCCATGGAGAC
GCGCTTCCTGCTGGCCGACAACCTGTACTGCAAGGCCTTGGTGCCCCCGACGGACAGGGTCTGC
CTGTGGCTGGGGGCCAACGTGATGCTGGAGTACGACGTGGACGAGGCCCGGGCGCTGCTGGAGA
AAAACCTGGCGACGGCGGCACGGAACCTGGAAGCCCTGGAGGACGACCTGGACTTCCTGCGGGA
CCAGTTCACCACCACGGAAGTCATCATGGCGCGCGTTTACAACTGGGACGTGAAGCGCATGAAC
CGGGACGATGGCGGGGCCACCAAGAGCAAAGCGTGAGGGCGCCGACCACTGCGCTCGCCCGCCC
GATGTCCGTCTCACGCCTGAACATTAATGTATAGCTCACCGGTTTAAATGTTTATCACACCCCA
TTTGTTTTTCCCTCCCTTCCCTCCCCACCCCACCCCCCACGGCGGGAATTAAAAACCCGAAGGG
ACGCCAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006229645 ⟹ XP_006229707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	148,425,046 - 148,443,505 (-)	NCBI
Rnor_5.0	1	154,704,249 - 154,723,093 (-)	NCBI

Sequence:

show sequence

CGGCCGCGCCGGAACCTCCGGACAACGGAGGACGCTGCCGAGAACCTCCCTGACATCACTTCCT
TCGCGCCCTCACTCCGCCGGGCCGCCAATCGCCCGCTGGCGGCCCACCGGAAGTGAGGCGGGAC
TCGGAGCCGGGGGCCGGAAGCTGCGCAGGTCACAGCTCGCTCCGCCTCCTTCCCAAGATGGCGG
CGGCTCAGGGAGGGCGCGGCTTGGAGGCGGGCAACGGTCGGCGGCTGCACCTGGGGATTCCAGA
AGCGGTGTTCGTGGAGGATGTGGACGCCTTCATGGCGCAGCCCGGAAATGAGAGCGCAGACGCC
GCGCTGCGGAAGCTGGACGAGCGCTACCAGAAATACAAGTTCATGGAGCTCAGCCTCGCACAGC
GCAAGCGCAGGCTGAAGTCGCAGATCCCTGAGATCAAGCAGACGCTGGAGATCCTCAAATACAT
GCAGCGGAAGAAGGGGTCGCCCCACGCCATGGAGACGCGCTTCCTGCTGGCCGACAACCTGTAC
TGCAAGGCCTTGGTGCCCCCGACGGACAGGGTCTGCCTGTGGCTGGGGGCCAACGTGATGCTGG
AGTACGACGTGGACGAGGCCCGGGCGCTGCTGGAGAAAAACCTGGCGACGGCGGCACGGAACCT
GGAAGCCCTGGAGGACGACCTGGACTTCCTGCGGGACCAGTTCACCACCACGGAAGTCAGTATC
CTGGACGTATGGACGGGGGCGGGGGGACAGGAGGGACGGTAAGAGTTCGTTCCTGGTTTAACGT
ATAGAAAATAGAGGAAAGGATGAGTTTATCCTCAGGATAACATATAGAGGAGAAAGACTAAGTT
TATTAATGTAAAGAAAAGAATAGATTTGTTCTTAATGTATAGAAAACGATGGGTTTGTTCTCGT
TAATGTGTAGAAAAGAACTGATTCACTCTTAATGTAAAGGAAACGTATAGAAAATAGAGGAAAG
GATGAGTTTATCCTCAGGTTAACATATAAAGGAGAAAGACTGAGTTTATTAATGTAAAGAAAAG
AATACATCTACTCTTACTGTATAGAAAAGGATGGACTCATTCCTGACTTAATGTATAGAAAAGA
ATGGGTTTGTTCTCAAGTTAATGTACAGGAAAGAAACAATCCATTCTTAATGTAAAGGAAAATG
TAAAGAACGGACTTATTCTCACACTAACGTAAGGAAGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001385629	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_001058594 ⟸ XM_001058594
- Peptide Label:	isoform X2
- Sequence:	show sequence MAAAQGGRGLEAGNGRRLHLGIPEAVFVEDVDAFMAQPGNESADAALRKLDERYQKYKFMELSL AQRKRRLKSQIPEIKQTLEILKYMQRKKGSPHAMETRFLLADNLYCKALVPPTDRVCLWLGANV MLEYDVDEARALLEKNLATAARNLEALEDDLDFLRDQFTTTEVIMARVYNWDVKRMNRDDGGAT KSKA hide sequence

RefSeq Acc Id:	XP_006229707 ⟸ XM_006229645
- Peptide Label:	isoform X1
- Sequence:	show sequence MAAAQGGRGLEAGNGRRLHLGIPEAVFVEDVDAFMAQPGNESADAALRKLDERYQKYKFMELSL AQRKRRLKSQIPEIKQTLEILKYMQRKKGSPHAMETRFLLADNLYCKALVPPTDRVCLWLGANV MLEYDVDEARALLEKNLATAARNLEALEDDLDFLRDQFTTTEVSILDVWTGAGGQEGR hide sequence

Ensembl Acc Id:

ENSRNOP00000065979 ⟸ ENSRNOT00000072973

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0R919-F1-model_v2	AlphaFold	M0R919	1-186	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690184

Promoter ID:

EPDNEW_R699

Type:

multiple initiation site

Name:

Vbp1_1

Description:

VHL binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	148,443,329 - 148,443,389	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1590535	AgrOrtholog
Ensembl Genes	ENSRNOG00000050401	Ensembl
Gene3D-CATH	1.10.287.370	UniProtKB/TrEMBL
InterPro	PFD3	UniProtKB/TrEMBL
	Prefoldin	UniProtKB/TrEMBL
	Prefoldin_subunit_alpha	UniProtKB/TrEMBL
NCBI Gene	681825	ENTREZGENE
PANTHER	PREFOLDIN SUBUNIT 3	UniProtKB/TrEMBL
	PREFOLDIN SUBUNIT 3	UniProtKB/TrEMBL
Pfam	Prefoldin	UniProtKB/TrEMBL
PhenoGen	Vbp1	PhenoGen
PIRSF	Prefoldin_subunit_3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000050401	RatGTEx
Superfamily-SCOP	Prefoldin	UniProtKB/TrEMBL
UniProt	A6KU95	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-03	Vbp1	VHL binding protein 1	Vbp1	von Hippel-Lindau binding protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-09	Vbp1	von Hippel-Lindau binding protein 1	LOC681825	similar to Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC681825	similar to Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar