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Gene: Serpinb7 (serpin family B member 7) Rattus norvegicus
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Symbol: Serpinb7
Name: serpin family B member 7
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in positive regulation of collagen biosynthetic process; positive regulation of cytokine production; and positive regulation of glomerular mesangial cell proliferation. Predicted to localize to the extracellular space. Biomarker of nephritis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINB7 (serpin family B member 7); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Megsin; serine (or cysteine) peptidase inhibitor, clade B, member 7; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7; serine (or cysteine) proteinase inhibitor, clade B, member 7; serpin B7; serpin peptidase inhibitor, clade B (ovalbumin), member 7
Orthologs:
Homo sapiens (human) : SERPINB7 (serpin family B member 7)  HGNC  Alliance
Mus musculus (house mouse) : Serpinb7 (serine (or cysteine) peptidase inhibitor, clade B, member 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinb7 (serpin family B member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINB7 (serpin family B member 7)
Canis lupus familiaris (dog) : SERPINB7 (serpin family B member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinb7 (serpin family B member 7)
Sus scrofa (pig) : SERPINB7 (serpin family B member 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01327,282,456 - 27,354,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01332,431,704 - 32,503,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,464,818 - 13,506,372 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11313,464,817 - 13,506,372 (+)NCBI
Celera1323,245,098 - 23,286,663 (+)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Serpinb7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71063
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.