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Gene: Sgms2 (sphingomyelin synthase 2) Rattus norvegicus
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Symbol: Sgms2
Name: sphingomyelin synthase 2
RGD ID: 1305778
Description: Predicted to have ceramide cholinephosphotransferase activity; ceramide phosphoethanolamine synthase activity; and sphingomyelin synthase activity. Predicted to be involved in regulation of bone mineralization and sphingolipid biosynthetic process. Localizes to integral component of plasma membrane. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Orthologous to human SGMS2 (sphingomyelin synthase 2); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC310849; phosphatidylcholine:ceramide cholinephosphotransferase 2; RGD1305778; similar to RIKEN cDNA 4933405A16; spermatin
Orthologs:
Homo sapiens (human) : SGMS2 (sphingomyelin synthase 2)  HGNC  Alliance
Mus musculus (house mouse) : Sgms2 (sphingomyelin synthase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgms2 (sphingomyelin synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SGMS2 (sphingomyelin synthase 2)
Canis lupus familiaris (dog) : SGMS2 (sphingomyelin synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgms2 (sphingomyelin synthase 2)
Sus scrofa (pig) : SGMS2 (sphingomyelin synthase 2)
Chlorocebus sabaeus (African green monkey) : SGMS2 (sphingomyelin synthase 2)
Heterocephalus glaber (naked mole-rat) : Sgms2 (sphingomyelin synthase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02236,458,276 - 236,530,667 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,458,279 - 236,480,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02255,006,742 - 255,078,076 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,815,312 - 228,838,295 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12228,802,052 - 228,825,035 (-)NCBI
Celera2212,149,475 - 212,172,550 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sgms2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305778
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.