Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Polr3g | Rat | 1,2-dichloroethane | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of POLR3G mRNA | CTD | PMID:28960355 | Polr3g | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Polr3g (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of POLR3G mRNA | CTD | PMID:22206623 | Polr3g | Rat | 17beta-estradiol | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Estradiol results in increased expression of POLR3G mRNA | CTD | PMID:23019147 and PMID:31614463 | Polr3g | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Polr3g (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of POLR3G mRNA | CTD | PMID:21570461 | Polr3g | Rat | 2-palmitoylglycerol | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of POLR3G mRNA | CTD | PMID:37199045 | Polr3g | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of POLR3G mRNA | CTD | PMID:28522335 | Polr3g | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of POLR3G mRNA | CTD | PMID:30723492 | Polr3g | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Polr3g (Mus musculus) | 6480464 | bisphenol S affects the methylation of POLR3G gene | CTD | PMID:31683443 | Polr3g | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | Fenretinide results in decreased expression of POLR3G mRNA | CTD | PMID:28973697 | Polr3g | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of POLR3G mRNA | CTD | PMID:25825206 | Polr3g | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of POLR3G mRNA | CTD | PMID:31881176 | Polr3g | Rat | aflatoxin B1 | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of POLR3G mRNA | CTD | PMID:21641981 | Polr3g | Rat | aflatoxin B1 | decreases methylation | ISO | POLR3G (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of POLR3G intron | CTD | PMID:30157460 | Polr3g | Rat | aflatoxin B1 | increases methylation | ISO | POLR3G (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of POLR3G gene | CTD | PMID:27153756 | Polr3g | Rat | alachlor | affects expression | EXP | | 6480464 | alachlor affects the expression of POLR3G mRNA | CTD | PMID:19425180 | Polr3g | Rat | all-trans-retinoic acid | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of POLR3G mRNA | CTD | PMID:21934132 and PMID:33167477 | Polr3g | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of POLR3G mRNA | CTD | PMID:35163327 | Polr3g | Rat | aristolochic acid A | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of POLR3G mRNA | CTD | PMID:33212167 | Polr3g | Rat | belinostat | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | belinostat results in increased expression of POLR3G mRNA | CTD | PMID:26272509 | Polr3g | Rat | belinostat | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | Polr3g | Rat | benzo[a]pyrene | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of POLR3G mRNA | CTD | PMID:32234424 | Polr3g | Rat | benzo[e]pyrene | increases methylation | ISO | POLR3G (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of POLR3G intron | CTD | PMID:30157460 | Polr3g | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of POLR3G mRNA | CTD | PMID:26377693 | Polr3g | Rat | bisphenol A | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | bisphenol A results in increased expression of POLR3G mRNA | CTD | PMID:21932408 | Polr3g | Rat | bisphenol A | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | bisphenol A results in increased expression of POLR3G mRNA | CTD | PMID:34831106 | Polr3g | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of POLR3G mRNA | CTD | PMID:34947998 | Polr3g | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of POLR3G mRNA | CTD | PMID:25181051 | Polr3g | Rat | bisphenol A | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | bisphenol A results in decreased expression of POLR3G mRNA | CTD | PMID:26063408 and PMID:33221593 | Polr3g | Rat | butanal | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of POLR3G mRNA | CTD | PMID:26079696 | Polr3g | Rat | calcitriol | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of POLR3G mRNA | CTD | PMID:21592394 | Polr3g | Rat | calcitriol | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of POLR3G mRNA | CTD | PMID:21592394 | Polr3g | Rat | carbon nanotube | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of POLR3G mRNA | CTD | PMID:25554681 | Polr3g | Rat | chlorpyrifos | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of POLR3G mRNA | CTD | PMID:37019170 | Polr3g | Rat | cisplatin | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of POLR3G mRNA | CTD | PMID:24280081 and PMID:27594783 | Polr3g | Rat | cisplatin | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | Cisplatin results in decreased expression of POLR3G mRNA | CTD | PMID:24280081 | Polr3g | Rat | copper(II) sulfate | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of POLR3G mRNA | CTD | PMID:19549813 | Polr3g | Rat | cyclosporin A | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of POLR3G mRNA | CTD | PMID:25562108 | Polr3g | Rat | DDE | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of POLR3G mRNA | CTD | PMID:38568856 | Polr3g | Rat | diclofenac | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | Diclofenac results in increased expression of POLR3G mRNA | CTD | PMID:35537566 | Polr3g | Rat | dioxygen | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of POLR3G mRNA | CTD | PMID:26516004 | Polr3g | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of POLR3G mRNA | CTD | PMID:33729688 | Polr3g | Rat | dorsomorphin | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Polr3g | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of POLR3G mRNA | CTD | PMID:29391264 | Polr3g | Rat | entinostat | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | entinostat results in increased expression of POLR3G mRNA | CTD | PMID:26272509 | Polr3g | Rat | entinostat | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | Polr3g | Rat | epoxiconazole | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of POLR3G mRNA | CTD | PMID:35436446 | Polr3g | Rat | ethanol | affects splicing | ISO | Polr3g (Mus musculus) | 6480464 | Ethanol affects the splicing of POLR3G mRNA | CTD | PMID:30319688 | Polr3g | Rat | ethyl methanesulfonate | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of POLR3G mRNA | CTD | PMID:23649840 | Polr3g | Rat | fluoranthene | multiple interactions | ISO | Polr3g (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of POLR3G mRNA | CTD | PMID:28329830 | Polr3g | Rat | folic acid | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | Folic Acid results in decreased expression of POLR3G mRNA | CTD | PMID:25629700 | Polr3g | Rat | formaldehyde | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of POLR3G mRNA | CTD | PMID:23649840 | Polr3g | Rat | FR900359 | decreases phosphorylation | ISO | POLR3G (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of POLR3G protein | CTD | PMID:37730182 | Polr3g | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of POLR3G mRNA | CTD | PMID:25539665 and PMID:26194646 | Polr3g | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of POLR3G gene | CTD | PMID:27387713 | Polr3g | Rat | irinotecan | increases response to substance | ISO | POLR3G (Homo sapiens) | 6480464 | POLR3G protein results in increased susceptibility to Irinotecan | CTD | PMID:16734730 | Polr3g | Rat | methapyrilene | increases methylation | ISO | POLR3G (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of POLR3G intron | CTD | PMID:30157460 | Polr3g | Rat | methyl methanesulfonate | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of POLR3G mRNA | CTD | PMID:23649840 | Polr3g | Rat | methylmercury chloride | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of POLR3G mRNA | CTD | PMID:23179753 more ... | Polr3g | Rat | methylmercury chloride | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | Polr3g | Rat | nickel atom | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Nickel results in increased expression of POLR3G mRNA | CTD | PMID:25583101 | Polr3g | Rat | nickel sulfate | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of POLR3G mRNA | CTD | PMID:22714537 | Polr3g | Rat | panobinostat | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | Polr3g | Rat | panobinostat | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | panobinostat results in increased expression of POLR3G mRNA | CTD | PMID:26272509 | Polr3g | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of POLR3G mRNA | CTD | PMID:32680482 | Polr3g | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of POLR3G mRNA | CTD | PMID:35163327 | Polr3g | Rat | pirinixic acid | multiple interactions | ISO | Polr3g (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of POLR3G mRNA | CTD | PMID:19710929 | Polr3g | Rat | potassium chromate | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of POLR3G mRNA | CTD | PMID:22714537 | Polr3g | Rat | quercetin | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Quercetin results in decreased expression of POLR3G mRNA | CTD | PMID:21632981 | Polr3g | Rat | rotenone | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | Rotenone results in increased expression of POLR3G mRNA | CTD | PMID:32937126 | Polr3g | Rat | SB 431542 | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Polr3g | Rat | silicon dioxide | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of POLR3G mRNA | CTD | PMID:25895662 | Polr3g | Rat | silicon dioxide | decreases expression | ISO | Polr3g (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of POLR3G mRNA | CTD | PMID:19073995 and PMID:23221170 | Polr3g | Rat | silver atom | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | Silver results in increased expression of POLR3G mRNA | CTD | PMID:27131904 | Polr3g | Rat | silver(0) | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | Silver results in increased expression of POLR3G mRNA | CTD | PMID:27131904 | Polr3g | Rat | sodium arsenite | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of POLR3G mRNA | CTD | PMID:22714537 | Polr3g | Rat | sodium arsenite | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of POLR3G mRNA | CTD | PMID:38568856 | Polr3g | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of POLR3G mRNA | CTD | PMID:25993096 | Polr3g | Rat | sunitinib | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Sunitinib results in increased expression of POLR3G mRNA | CTD | PMID:31533062 | Polr3g | Rat | tamoxifen | affects expression | ISO | Polr3g (Mus musculus) | 6480464 | Tamoxifen affects the expression of POLR3G mRNA | CTD | PMID:20937368 | Polr3g | Rat | temozolomide | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Temozolomide results in increased expression of POLR3G mRNA | CTD | PMID:31758290 | Polr3g | Rat | testosterone | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of POLR3G mRNA | CTD | PMID:21592394 | Polr3g | Rat | testosterone | decreases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Testosterone results in decreased expression of POLR3G mRNA | CTD | PMID:21592394 | Polr3g | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of POLR3G mRNA | CTD | PMID:31150632 | Polr3g | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of POLR3G mRNA | CTD | PMID:34492290 | Polr3g | Rat | thiram | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Thiram results in increased expression of POLR3G mRNA | CTD | PMID:38568856 | Polr3g | Rat | trichostatin A | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | trichostatin A results in increased expression of POLR3G mRNA | CTD | PMID:24935251 more ... | Polr3g | Rat | trichostatin A | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | Polr3g | Rat | trovafloxacin | increases expression | ISO | Polr3g (Mus musculus) | 6480464 | trovafloxacin results in increased expression of POLR3G mRNA | CTD | PMID:35537566 | Polr3g | Rat | urethane | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Urethane results in increased expression of POLR3G mRNA | CTD | PMID:28818685 | Polr3g | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of POLR3G mRNA | CTD | PMID:24136188 | Polr3g | Rat | valproic acid | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of POLR3G mRNA | CTD | PMID:23179753 more ... | Polr3g | Rat | valproic acid | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | Polr3g | Rat | vanadyl sulfate | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | vanadyl sulfate results in increased expression of POLR3G mRNA | CTD | PMID:16330358 | Polr3g | Rat | vorinostat | increases expression | ISO | POLR3G (Homo sapiens) | 6480464 | vorinostat results in increased expression of POLR3G mRNA | CTD | PMID:26272509 | Polr3g | Rat | vorinostat | multiple interactions | ISO | POLR3G (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA | CTD | PMID:27188386 | |