Polr3g (polymerase (RNA) III (DNA directed) polypeptide G) - Rat Genome Database

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Gene: Polr3g (polymerase (RNA) III (DNA directed) polypeptide G) Mus musculus
Analyze
Symbol: Polr3g
Name: polymerase (RNA) III (DNA directed) polypeptide G
RGD ID: 1615105
MGI Page MGI
Description: Enables chromatin binding activity. Acts upstream of or within epithelial cell proliferation. Is active in nucleus. Is expressed in neocortex. Orthologous to human POLR3G (RNA polymerase III subunit G).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2310047G20Rik; AV275904; DNA-directed RNA polymerase III subunit G; DNA-directed RNA polymerase III subunit RPC7; RNA polymerase III subunit C7; RPC; RPC32; RPC7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391381,821,956 - 81,859,132 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1381,821,962 - 81,859,132 (-)EnsemblGRCm39 Ensembl
GRCm381381,673,837 - 81,711,013 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1381,673,843 - 81,711,013 (-)EnsemblGRCm38mm10GRCm38
MGSCv371381,812,836 - 81,850,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361382,151,174 - 82,188,912 (-)NCBIMGSCv36mm8
Celera1383,934,554 - 83,971,713 (-)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1343.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
alachlor  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
cisplatin  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diclofenac  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fluoranthene  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (ISO)
irinotecan  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
trichostatin A  (ISO)
trovafloxacin  (EXP)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IDA,ISO)
RNA polymerase III complex  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription. Dumay-Odelot H, etal., Cell Cycle. 2010 Sep 15;9(18):3687-99. Epub 2010 Sep 1.
2. Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. Hu P, etal., Mol Cell Biol. 2002 Nov;22(22):8044-55.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9171375   PMID:10349636   PMID:10512203   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:14681479  
PMID:15489334   PMID:15840001   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21898682   PMID:24107381   PMID:25556833   PMID:30973865  
PMID:32576691  


Genomics

Comparative Map Data
Polr3g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391381,821,956 - 81,859,132 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1381,821,962 - 81,859,132 (-)EnsemblGRCm39 Ensembl
GRCm381381,673,837 - 81,711,013 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1381,673,843 - 81,711,013 (-)EnsemblGRCm38mm10GRCm38
MGSCv371381,812,836 - 81,850,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361382,151,174 - 82,188,912 (-)NCBIMGSCv36mm8
Celera1383,934,554 - 83,971,713 (-)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1343.68NCBI
POLR3G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38590,473,929 - 90,514,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl590,471,748 - 90,514,557 (+)EnsemblGRCh38hg38GRCh38
GRCh37589,769,746 - 89,810,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36589,806,437 - 89,846,125 (+)NCBINCBI36Build 36hg18NCBI36
Build 34589,806,481 - 89,843,881NCBI
Celera585,672,528 - 85,712,495 (+)NCBICelera
Cytogenetic Map5q14.3NCBI
HuRef584,981,329 - 85,021,025 (+)NCBIHuRef
CHM1_1589,203,359 - 89,243,046 (+)NCBICHM1_1
T2T-CHM13v2.0590,960,487 - 91,001,143 (+)NCBIT2T-CHM13v2.0
Polr3g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8213,680,893 - 13,721,802 (-)NCBIGRCr8
mRatBN7.2211,945,215 - 11,986,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl211,945,217 - 11,986,125 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx219,058,971 - 19,099,261 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0217,158,491 - 17,198,782 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0211,813,031 - 11,853,624 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.029,537,642 - 9,578,551 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl29,537,642 - 9,578,310 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.029,417,663 - 9,458,293 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.429,763,378 - 9,804,285 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera28,304,852 - 8,345,111 (-)NCBICelera
Cytogenetic Map2q11NCBI
Polr3g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541821,116,812 - 21,149,818 (-)NCBIChiLan1.0ChiLan1.0
POLR3G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2424,880,067 - 24,920,347 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1523,033,851 - 23,073,989 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0524,855,517 - 24,896,051 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1524,989,905 - 25,030,180 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl524,992,158 - 25,019,272 (-)Ensemblpanpan1.1panPan2
POLR3G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1318,426,169 - 18,529,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl318,427,985 - 18,467,801 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha319,793,797 - 19,896,582 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0318,332,611 - 18,433,936 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl318,332,616 - 18,374,264 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1318,306,259 - 18,409,054 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0318,271,553 - 18,374,844 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0318,560,360 - 18,663,292 (-)NCBIUU_Cfam_GSD_1.0
Polr3g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213174,015,683 - 174,051,672 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364698,574,120 - 8,611,643 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR3G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1297,646,112 - 97,688,255 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22100,726,267 - 100,766,345 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POLR3G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1484,418,692 - 84,459,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604933,477,530 - 33,519,561 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polr3g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247439,733,372 - 9,765,967 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Polr3g
1281 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1000
Count of miRNA genes:578
Interacting mature miRNAs:712
Transcripts:ENSMUST00000048993, ENSMUST00000160331, ENSMUST00000161093, ENSMUST00000161920, ENSMUST00000162535
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
1301610Dps1_mdelta power in slow-wave sleep 1 (mouse)Not determined137719586295730894Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
12880402Emlq1_memotional learning QTL 1 (mouse)137810885896866553Mouse
12879495Fexq1_mfear expression QTL 1 (mouse)137826885895836553Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse

Markers in Region
AV275904  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381381,673,881 - 81,673,976UniSTSGRCm38
MGSCv371381,812,880 - 81,812,975UniSTSGRCm37
Celera1383,934,598 - 83,934,693UniSTS
Cytogenetic Map13C3UniSTS
Whitehead/MRC_RH13692.64UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000048993   ⟹   ENSMUSP00000035289
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1381,821,962 - 81,859,132 (-)Ensembl
GRCm38.p6 Ensembl1381,673,843 - 81,711,013 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160331
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1381,847,500 - 81,859,121 (-)Ensembl
GRCm38.p6 Ensembl1381,699,381 - 81,711,002 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161093
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1381,841,965 - 81,859,075 (-)Ensembl
GRCm38.p6 Ensembl1381,693,846 - 81,710,956 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161920   ⟹   ENSMUSP00000125054
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1381,842,402 - 81,859,064 (-)Ensembl
GRCm38.p6 Ensembl1381,694,283 - 81,710,945 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162535
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1381,821,999 - 81,835,404 (-)Ensembl
GRCm38.p6 Ensembl1381,673,880 - 81,687,285 (-)Ensembl
RefSeq Acc Id: NM_001081176   ⟹   NP_001074645
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391381,821,956 - 81,859,132 (-)NCBI
GRCm381381,673,837 - 81,711,013 (-)ENTREZGENE
MGSCv371381,812,836 - 81,850,012 (-)RGD
Celera1383,934,554 - 83,971,713 (-)RGD
cM Map13 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001074645 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH30063 (Get FASTA)   NCBI Sequence Viewer  
  AAH66818 (Get FASTA)   NCBI Sequence Viewer  
  BAB26717 (Get FASTA)   NCBI Sequence Viewer  
  EDL37141 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000035289
  ENSMUSP00000035289.6
  ENSMUSP00000125054.2
GenBank Protein Q6NXY9 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001074645   ⟸   NM_001081176
- UniProtKB: Q8K0W5 (UniProtKB/Swiss-Prot),   Q9CV05 (UniProtKB/Swiss-Prot),   Q6NXY9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000035289   ⟸   ENSMUST00000048993
RefSeq Acc Id: ENSMUSP00000125054   ⟸   ENSMUST00000161920

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6NXY9-F1-model_v2 AlphaFold Q6NXY9 1-223 view protein structure

Promoters
RGD ID:8680900
Promoter ID:EPDNEW_M18481
Type:initiation region
Name:Polr3g_1
Description:Mus musculus polymerase III polypeptide G , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381381,711,002 - 81,711,062EPDNEW
RGD ID:6824271
Promoter ID:MM_KWN:14797
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:NM_001081176,   NM_028372,   UC007RHZ.1,   UC007RIB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361381,849,936 - 81,850,972 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914736 AgrOrtholog
Ensembl Genes ENSMUSG00000035834 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000048993 ENTREZGENE
  ENSMUST00000048993.12 UniProtKB/Swiss-Prot
  ENSMUST00000161920.2 UniProtKB/Swiss-Prot
InterPro RNA_pol_III_Rpc31 UniProtKB/Swiss-Prot
KEGG Report mmu:67486 UniProtKB/Swiss-Prot
MGD MGI:1914736 ENTREZGENE
NCBI Gene 67486 ENTREZGENE
PANTHER DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7 UniProtKB/Swiss-Prot
  PTHR15367 UniProtKB/Swiss-Prot
Pfam RNA_pol_3_Rpc31 UniProtKB/Swiss-Prot
PhenoGen Polr3g PhenoGen
UniProt Q6NXY9 ENTREZGENE
  Q8K0W5 ENTREZGENE
  Q9CV05 ENTREZGENE
  RPC7_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8K0W5 UniProtKB/Swiss-Prot
  Q9CV05 UniProtKB/Swiss-Prot