Cltb (clathrin, light chain B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cltb (clathrin, light chain B) Rattus norvegicus
Analyze
Symbol: Cltb
Name: clathrin, light chain B
RGD ID: 621353
Description: Enables peptide binding activity. Involved in synaptic vesicle endocytosis. Part of clathrin coat. Is active in presynaptic endocytic zone membrane and synaptic vesicle membrane. Orthologous to human CLTB (clathrin light chain B); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: clathrin light chain B; clathrin, light chain (Lcb); clathrin, light polypeptide (Lcb); lcb
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81710,006,416 - 10,024,278 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1710,006,656 - 10,024,915 (+)EnsemblGRCr8
mRatBN7.21710,001,512 - 10,019,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1710,001,513 - 10,019,169 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1710,015,877 - 10,033,469 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,549,271 - 11,566,824 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01710,012,314 - 10,029,907 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,537,348 - 10,554,999 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,537,365 - 10,554,989 (+)Ensemblrn6Rnor6.0
Rnor_5.01712,665,115 - 12,682,779 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41716,063,715 - 16,081,277 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1710,074,602 - 10,092,160 (+)NCBICelera
RGSC_v3.11716,063,714 - 16,081,277 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
buspirone  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
clozapine  (EXP)
cobalt dichloride  (EXP,ISO)
cocaine  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
furan  (EXP)
furfural  (ISO)
haloperidol  (EXP)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
Mesaconitine  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
picoxystrobin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs. Kirchhausen T, etal., Science 1987 Apr 17;236(4799):320-4.
4. Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling. Maycox PR, etal., J Cell Biol. 1992 Sep;118(6):1379-88.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Monitoring clathrin-mediated endocytosis during synaptic activity. Mueller VJ, etal., J Neurosci. 2004 Feb 25;24(8):2004-12.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. A motif in the clathrin heavy chain required for the Hsc70/auxilin uncoating reaction. Rapoport I, etal., Mol Biol Cell. 2008 Jan;19(1):405-13. Epub 2007 Oct 31.
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
13. Possible involvement of clathrin in neuritogenesis induced by a protease inhibitor (benzyloxycarbonyl-Leu-Leu-Leu-aldehyde) in PC12 cells. Saito Y, etal., J Biochem. 1992 Oct;112(4):448-55.
Additional References at PubMed
PMID:9188501   PMID:16025302   PMID:20427320   PMID:25427558   PMID:28259758   PMID:29476059   PMID:35352799  


Genomics

Comparative Map Data
Cltb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81710,006,416 - 10,024,278 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1710,006,656 - 10,024,915 (+)EnsemblGRCr8
mRatBN7.21710,001,512 - 10,019,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1710,001,513 - 10,019,169 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1710,015,877 - 10,033,469 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,549,271 - 11,566,824 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01710,012,314 - 10,029,907 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,537,348 - 10,554,999 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,537,365 - 10,554,989 (+)Ensemblrn6Rnor6.0
Rnor_5.01712,665,115 - 12,682,779 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41716,063,715 - 16,081,277 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1710,074,602 - 10,092,160 (+)NCBICelera
RGSC_v3.11716,063,714 - 16,081,277 (+)NCBI
Cytogenetic Map17p14NCBI
CLTB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385176,392,455 - 176,416,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5176,392,501 - 176,416,539 (-)Ensemblhg38GRCh38
GRCh375175,819,456 - 175,843,570 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365175,752,062 - 175,776,146 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345175,752,061 - 175,776,146NCBI
Celera5172,658,136 - 172,682,645 (+)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5170,744,066 - 170,767,978 (-)NCBIHuRef
CHM1_15175,252,405 - 175,276,513 (-)NCBICHM1_1
T2T-CHM13v2.05176,936,813 - 176,960,926 (-)NCBIT2T-CHM13v2.0
Cltb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391354,740,199 - 54,759,186 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1354,740,214 - 54,759,157 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381354,592,386 - 54,611,373 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,592,401 - 54,611,344 (-)Ensemblmm10GRCm38
MGSCv371354,694,300 - 54,712,633 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361354,602,561 - 54,620,894 (-)NCBIMGSCv36mm8
MGSCv361354,074,085 - 54,092,362 (-)NCBIMGSCv36mm8
Celera1355,659,315 - 55,676,939 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1328.84NCBI
Cltb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,692,933 - 28,717,566 (-)Ensembl
ChiLan1.0NW_00495540828,692,933 - 28,717,566 (-)NCBIChiLan1.0ChiLan1.0
CLTB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24171,471,598 - 171,495,555 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15169,611,137 - 169,635,060 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05171,689,273 - 171,713,198 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15178,761,419 - 178,784,410 (-)NCBIPanPan1.1PanPan1.1panPan2
CLTB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,915,106 - 36,935,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl436,791,891 - 36,935,278 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha436,882,656 - 36,903,076 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0437,282,765 - 37,303,184 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl437,282,782 - 37,303,562 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1437,108,273 - 37,128,468 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0437,295,663 - 37,316,063 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0437,804,632 - 37,825,064 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cltb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213121,639,288 - 121,664,966 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936597662,725 - 689,873 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936597665,365 - 689,867 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLTB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,464,917 - 81,485,419 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1281,464,887 - 81,484,712 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2283,066,549 - 83,082,535 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLTB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12378,396,089 - 78,420,860 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,396,413 - 78,420,819 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660759,524,741 - 9,551,170 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cltb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473313,707,155 - 13,738,814 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473313,707,594 - 13,738,814 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Cltb
81 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:452
Count of miRNA genes:152
Interacting mature miRNAs:168
Transcripts:ENSRNOT00000023651, ENSRNOT00000032402
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17926675540968173Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920650523859062Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920650523859062Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17798524316523460Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920650523859062Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920650523859062Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
BE110258  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21710,008,215 - 10,008,367 (+)MAPPERmRatBN7.2
Rnor_6.01710,544,052 - 10,544,203NCBIRnor6.0
Rnor_5.01712,671,801 - 12,671,952UniSTSRnor5.0
RGSC_v3.41716,070,328 - 16,070,479UniSTSRGSC3.4
Celera1710,081,220 - 10,081,371UniSTS
RH 3.4 Map1792.5UniSTS
Cytogenetic Map17p14UniSTS
BE105422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21710,017,272 - 10,017,475 (+)MAPPERmRatBN7.2
Rnor_6.01710,553,102 - 10,553,304NCBIRnor6.0
Rnor_5.01712,680,851 - 12,681,053UniSTSRnor5.0
RGSC_v3.41716,079,381 - 16,079,583UniSTSRGSC3.4
Celera1710,090,264 - 10,090,466UniSTS
RH 3.4 Map1797.2UniSTS
Cytogenetic Map17p14UniSTS
CLTB_4592  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21710,018,803 - 10,019,416 (+)MAPPERmRatBN7.2
Rnor_6.01710,554,633 - 10,555,245NCBIRnor6.0
Rnor_5.01712,682,382 - 12,682,994UniSTSRnor5.0
RGSC_v3.41716,080,912 - 16,081,524UniSTSRGSC3.4
Celera1710,091,795 - 10,092,407UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000023651   ⟹   ENSRNOP00000023651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1710,006,696 - 10,024,915 (+)Ensembl
mRatBN7.2 Ensembl1710,001,513 - 10,019,169 (+)Ensembl
Rnor_6.0 Ensembl1710,537,365 - 10,554,989 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115689   ⟹   ENSRNOP00000085439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1710,006,656 - 10,024,915 (+)Ensembl
mRatBN7.2 Ensembl1710,001,584 - 10,019,160 (+)Ensembl
RefSeq Acc Id: NM_053835   ⟹   NP_446287
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81710,006,715 - 10,024,277 (+)NCBI
mRatBN7.21710,001,603 - 10,019,169 (+)NCBI
Rnor_6.01710,537,439 - 10,554,998 (+)NCBI
Rnor_5.01712,665,115 - 12,682,779 (+)NCBI
RGSC_v3.41716,063,715 - 16,081,277 (+)RGD
Celera1710,074,602 - 10,092,160 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253595   ⟹   XP_006253657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81710,006,416 - 10,024,278 (+)NCBI
mRatBN7.21710,001,512 - 10,019,201 (+)NCBI
Rnor_6.01710,537,348 - 10,554,999 (+)NCBI
Rnor_5.01712,665,115 - 12,682,779 (+)NCBI
Sequence:
RefSeq Acc Id: NP_446287   ⟸   NM_053835
- UniProtKB: P08082 (UniProtKB/Swiss-Prot),   A6KAY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253657   ⟸   XM_006253595
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000023651   ⟸   ENSRNOT00000023651
Ensembl Acc Id: ENSRNOP00000085439   ⟸   ENSRNOT00000115689

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08082-F1-model_v2 AlphaFold P08082 1-229 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700321
Promoter ID:EPDNEW_R10844
Type:initiation region
Name:Cltb_1
Description:clathrin, light chain B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01710,537,387 - 10,537,447EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621353 AgrOrtholog
BioCyc Gene G2FUF-10176 BioCyc
Ensembl Genes ENSRNOG00000017506 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023651 ENTREZGENE
  ENSRNOT00000023651.7 UniProtKB/Swiss-Prot
  ENSRNOT00000115689 ENTREZGENE
  ENSRNOT00000115689.1 UniProtKB/Swiss-Prot
InterPro Clathrin_L-chain UniProtKB/Swiss-Prot
KEGG Report rno:116561 UniProtKB/Swiss-Prot
NCBI Gene 116561 ENTREZGENE
PANTHER CLATHRIN LIGHT CHAIN B UniProtKB/Swiss-Prot
  PTHR10639 UniProtKB/Swiss-Prot
Pfam Clathrin_lg_ch UniProtKB/Swiss-Prot
PhenoGen Cltb PhenoGen
PROSITE CLATHRIN_LIGHT_CHN_1 UniProtKB/Swiss-Prot
  CLATHRIN_LIGHT_CHN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017506 RatGTEx
UniProt A6KAY1_RAT UniProtKB/TrEMBL
  A6KAY2 ENTREZGENE, UniProtKB/TrEMBL
  A6KAY3 ENTREZGENE, UniProtKB/TrEMBL
  A6KAY4_RAT UniProtKB/TrEMBL
  A6KAY5_RAT UniProtKB/TrEMBL
  CLCB_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Cltb  clathrin, light chain B  Cltb  clathrin, light chain (Lcb)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Cltb  clathrin, light chain (Lcb)  Cltb  clathrin, light polypeptide (Lcb)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cltb  clathrin, light polypeptide (Lcb)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cltb  clathrin, light polypeptide (Lcb)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression alternatively spliced isoform Lcb2 is expressed specifically in brain neurons, while isoform Lcb3 is expressed in other tissues 728399
gene_transcript Lcb2 and Lcb3 are alternatively spliced isoforms 728399