Gene: Fli1 (Fli-1 proto-oncogene, ETS transcription factor) Rattus norvegicus
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Symbol: Fli1
Name: Fli-1 proto-oncogene, ETS transcription factor
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II distal enhancer sequence-specific DNA binding (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); blood circulation (ortholog); megakaryocyte development (ortholog); ASSOCIATED WITH Ewing sarcoma (ortholog); Experimental Liver Cirrhosis (ortholog); medulloblastoma (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 4,4'-diaminodiphenylmethane
AGR Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific, chromatin binding activity, and nucleic acid binding activity; predicted to be involved in animal organ development, blood circulation, and positive regulation of transcription by RNA polymerase II; predicted to localize to the cytosol and nuclear body; orthologous to human FLI1 (Fli-1 proto-oncogene, ETS transcription factor).
Merged Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific, chromatin binding activity, and nucleic acid binding activity; predicted to be involved in animal organ development, blood circulation, and positive regulation of transcription by RNA polymerase II; predicted to localize to the cytosol and nuclear body; orthologous to human FLI1 (Fli-1 proto-oncogene, ETS transcription factor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Friend leukemia integration 1; Friend leukemia integration 1 transcription factor; Friend leukemia integration 1 transcription factor-like; Friend leukemia virus integration 1; LOC100910769; LOC315532
Orthologs:
Homo sapiens (human) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Fli1 (Friend leukemia integration 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fli1 (Fli-1 proto-oncogene, ETS transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
Canis lupus familiaris (dog) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fli1 (Fli-1 proto-oncogene, ETS transcription factor)
Sus scrofa (pig) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0833,541,932 - 33,661,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0833,586,162 - 33,704,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,187,952 - 32,309,782 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1832,196,722 - 32,318,548 (-)NCBI
Celera832,284,160 - 32,401,673 (-)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fli1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309837
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.