Mir130b (microRNA 130b) - Rat Genome Database

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Gene: Mir130b (microRNA 130b) Rattus norvegicus
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Symbol: Mir130b
Name: microRNA 130b
RGD ID: 2325573
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including lipoprotein transport; miRNA-mediated gene silencing; and negative regulation of cholesterol efflux. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and sensory perception of sound. Orthologous to human MIR130B (microRNA 130b); INTERACTS WITH 2,5-hexanedione; 2-acetamidofluorene; aflatoxin B1.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-130b; rno-mir-130b
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,880,163 - 83,880,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,880,163 - 83,880,244 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,603,886 - 92,603,967 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01185,265,028 - 85,265,109 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01184,318,609 - 84,318,690 (+)NCBIRnor_WKY
Rnor_6.01188,129,773 - 88,129,854 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,773 - 88,129,854 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,182,320 - 91,182,401 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1182,635,894 - 82,635,975 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14691248   PMID:16381832   PMID:16766679   PMID:17604727   PMID:20403161   PMID:20439489   PMID:23646144   PMID:26255201   PMID:28412322   PMID:29995562   PMID:33300069   PMID:34080640  
PMID:35435532  


Genomics

Comparative Map Data
Mir130b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,880,163 - 83,880,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,880,163 - 83,880,244 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,603,886 - 92,603,967 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01185,265,028 - 85,265,109 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01184,318,609 - 84,318,690 (+)NCBIRnor_WKY
Rnor_6.01188,129,773 - 88,129,854 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,773 - 88,129,854 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,182,320 - 91,182,401 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1182,635,894 - 82,635,975 (+)NCBICelera
Cytogenetic Map11q23NCBI
MIR130B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,653,304 - 21,653,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2221,653,304 - 21,653,385 (+)EnsemblGRCh38hg38GRCh38
GRCh372222,007,593 - 22,007,674 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,337,592 - 20,337,673 (+)NCBINCBI36Build 36hg18NCBI36
Celera225,825,133 - 5,825,214 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,965,417 - 4,965,498 (+)NCBIHuRef
CHM1_12222,007,785 - 22,007,866 (+)NCBICHM1_1
T2T-CHM13v2.02222,066,795 - 22,066,876 (+)NCBIT2T-CHM13v2.0
Mir130b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,941,925 - 16,942,006 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,941,925 - 16,942,006 (-)EnsemblGRCm39 Ensembl
GRCm381617,124,061 - 17,124,142 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,124,061 - 17,124,142 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,124,154 - 17,124,235 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1617,696,855 - 17,696,936 (-)NCBICelera
Cytogenetic Map16A3NCBI

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:9927
Count of gene targets:6083
Count of transcripts:6563
Interacting mature miRNAs:rno-miR-130b-3p, rno-miR-130b-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system renal system reproductive system
High
Medium
Low 1 1 2 2
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000053664
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,880,163 - 83,880,244 (+)Ensembl
Rnor_6.0 Ensembl1188,129,773 - 88,129,854 (+)Ensembl
RefSeq Acc Id: NR_031877
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,880,163 - 83,880,244 (+)NCBI
Rnor_6.01188,129,773 - 88,129,854 (+)NCBI
Rnor_5.01191,182,320 - 91,182,401 (+)NCBI
Celera1182,635,894 - 82,635,975 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325573 AgrOrtholog
BioCyc Gene G2FUF-20568 BioCyc
Ensembl Genes ENSRNOG00000035541 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053664 ENTREZGENE
miRBase MI0000904 ENTREZGENE
NCBI Gene 100314028 ENTREZGENE
PhenoGen Mir130b PhenoGen
RNAcentral URS00002C0FCB RNACentral
  URS00003BD810 RNACentral
  URS000075B26D RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir130b  microRNA 130b  Mir130b  microRNA mir-130b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir130b  microRNA mir-130b      Symbol and Name status set to provisional 70820 PROVISIONAL