Kirrel3 (kirre like nephrin family adhesion molecule 3)

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Gene: Kirrel3 (kirre like nephrin family adhesion molecule 3) Rattus norvegicus

Analyze

Symbol:

Kirrel3

Name:

kirre like nephrin family adhesion molecule 3

RGD ID:

1311382

Description:

Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in hemopoiesis; homophilic cell adhesion via plasma membrane adhesion molecules; and nervous system development. Predicted to act upstream of or within glomerulus morphogenesis; inter-male aggressive behavior; and nervous system development. Predicted to be located in several cellular components, including axon; dendritic shaft; and synaptic vesicle. Predicted to be integral component of membrane. Predicted to be active in cell-cell junction. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 4. Orthologous to human KIRREL3 (kirre like nephrin family adhesion molecule 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

kin of IRRE like 3; kin of IRRE like 3 (Drosophila); kin of IRRE-like protein 3; LOC315546

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	32,865,779 - 33,407,555 (+)	NCBI	mRatBN7.2
Rnor_6.0 Ensembl	8	36,125,999 - 36,254,753 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	8	35,692,525 - 36,254,755 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	35,722,596 - 36,273,792 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	34,300,350 - 34,835,957 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	8	34,425,084 - 34,844,541 (+)	NCBI
Celera	8	34,284,951 - 34,824,973 (+)	NCBI		Celera
Cytogenetic Map	8	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

autosomal dominant non-syndromic intellectual disability 4 (ISO)

Developmental Disabilities (ISO)

Dwarfism (ISO)

intellectual disability (ISO)

Jacobsen Syndrome (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bromobenzene (EXP)

carbamazepine (ISO)

casticin (ISO)

cisplatin (ISO)

cocaine (ISO)

copper atom (EXP)

copper(0) (EXP)

crocidolite asbestos (ISO)

dexamethasone (ISO)

dorsomorphin (ISO)

folic acid (ISO)

indometacin (ISO)

lead diacetate (ISO)

methapyrilene (ISO)

monosodium L-glutamate (ISO)

nickel sulfate (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

potassium bromate (EXP)

propanal (ISO)

rifampicin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

testosterone (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell-cell adhesion (IBA)

glomerulus morphogenesis (ISO)

hemopoiesis (ISO)

hippocampus development (ISO)

homophilic cell adhesion via plasma membrane adhesion molecules (ISO)

inter-male aggressive behavior (ISO)

neuron migration (ISO)

neuron projection morphogenesis (ISO)

principal sensory nucleus of trigeminal nerve development (ISO)

synapse assembly (IBA,ISO)

Cellular Component

axon (ISO)

cell-cell junction (IBA)

dendrite (ISO)

dendritic shaft (ISO)

extracellular region (ISO)

integral component of membrane (ISO)

integral component of plasma membrane (IBA)

plasma membrane (ISO)

synaptic vesicle (ISO)

Molecular Function

cell adhesion molecule binding (IBA)

protein binding (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	MGD data from the GO Consortium
3.	OMIM Disease Annotation Pipeline
4.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12665856	PMID:16874800	PMID:21241806	PMID:23637329	PMID:25902260	PMID:26575286

Genomics

Comparative Map Data

Kirrel3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	32,865,779 - 33,407,555 (+)	NCBI	mRatBN7.2
Rnor_6.0 Ensembl	8	36,125,999 - 36,254,753 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	8	35,692,525 - 36,254,755 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	35,722,596 - 36,273,792 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	34,300,350 - 34,835,957 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	8	34,425,084 - 34,844,541 (+)	NCBI
Celera	8	34,284,951 - 34,824,973 (+)	NCBI		Celera
Cytogenetic Map	8	q21	NCBI

KIRREL3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	11	126,423,358 - 127,003,460 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	11	126,423,358 - 127,003,460 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	11	126,293,253 - 126,870,766 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	125,799,613 - 126,375,701 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	11	125,799,684 - 126,375,615	NCBI
Celera	11	123,459,514 - 124,037,646 (-)	NCBI
Cytogenetic Map	11	q24.2	NCBI
HuRef	11	122,817,366 - 122,817,789 (-)	NCBI		HuRef
HuRef	11	122,238,286 - 122,410,924 (-)	NCBI		HuRef
CHM1_1	11	126,179,676 - 126,756,915 (-)	NCBI		CHM1_1

Kirrel3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	34,396,850 - 34,952,103 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	9	34,397,190 - 34,948,012 (+)	Ensembl
GRCm38	9	34,485,853 - 35,040,807 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	34,485,894 - 35,036,716 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	34,296,316 - 34,843,889 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	34,238,296 - 34,785,975 (+)	NCBI			mm8
Celera	9	31,740,583 - 32,293,826 (+)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI

Kirrel3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	27,428,360 - 27,991,321 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	27,428,360 - 27,994,458 (-)	NCBI	ChiLan1.0	ChiLan1.0

KIRREL3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	125,146,563 - 125,726,452 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	125,146,563 - 125,723,504 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	121,236,962 - 121,821,806 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

KIRREL3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	7,583,530 - 8,124,045 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	7,583,805 - 8,123,080 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	7,645,744 - 8,184,370 (+)	NCBI
ROS_Cfam_1.0	5	7,538,980 - 8,078,718 (+)	NCBI
UMICH_Zoey_3.1	5	7,996,350 - 8,148,415 (+)	NCBI
UNSW_CanFamBas_1.0	5	7,583,374 - 8,122,445 (+)	NCBI
UU_Cfam_GSD_1.0	5	7,616,414 - 8,156,314 (+)	NCBI

Kirrel3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	108,652,952 - 108,687,285 (-)	NCBI
SpeTri2.0	NW_004936572	5,763,098 - 5,797,410 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KIRREL3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	53,491,950 - 54,063,480 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	53,493,735 - 54,066,490 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	59,332,982 - 59,498,767 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KIRREL3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	117,553,388 - 118,122,895 (-)	NCBI
ChlSab1.1	1	117,553,388 - 118,122,895 (-)	NCBI
ChlSab1.1 Ensembl	1	117,551,940 - 117,687,637 (-)	Ensembl
Vero_WHO_p1.0	NW_023666043	7,949,043 - 8,520,592 (+)	NCBI

Kirrel3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624812	561,290 - 1,158,012 (-)	NCBI

Position Markers

D8Rat100

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,343,218 - 33,343,426 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	36,181,831 - 36,182,038	NCBI	Rnor6.0
Rnor_5.0	8	36,203,861 - 36,204,068	UniSTS	Rnor5.0
RGSC_v3.4	8	34,773,456 - 34,773,664	RGD	RGSC3.4
RGSC_v3.4	8	34,773,457 - 34,773,664	UniSTS	RGSC3.4
RGSC_v3.1	8	34,782,222 - 34,782,430	RGD
Celera	8	34,761,230 - 34,761,437	UniSTS
FHH x ACI Map	8	26.99	RGD
FHH x ACI Map	8	26.99	UniSTS
Cytogenetic Map	8	q21	UniSTS

D3Mco55

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,161,693 - 33,161,853 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	35,996,819 - 35,996,978	NCBI	Rnor6.0
Rnor_5.0	8	36,023,372 - 36,023,531	UniSTS	Rnor5.0
RGSC_v3.4	8	34,589,399 - 34,589,558	UniSTS	RGSC3.4
RGSC_v3.4	3	168,596,925 - 168,597,084	UniSTS	RGSC3.4
Celera	8	34,580,747 - 34,580,906	UniSTS
Cytogenetic Map	8	q21	UniSTS

D8Got342

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	32,880,533 - 32,880,641 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	35,707,396 - 35,707,503	NCBI	Rnor6.0
Rnor_5.0	8	35,737,551 - 35,737,658	UniSTS	Rnor5.0
RGSC_v3.4	8	34,315,019 - 34,315,126	UniSTS	RGSC3.4
Celera	8	34,299,654 - 34,299,761	UniSTS
Cytogenetic Map	8	q21	UniSTS

BF386659

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,400,488 - 33,400,638 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	36,249,564 - 36,249,713	NCBI	Rnor6.0
Rnor_5.0	8	36,268,601 - 36,268,750	UniSTS	Rnor5.0
RGSC_v3.4	8	34,830,766 - 34,830,915	UniSTS	RGSC3.4
Celera	8	34,819,782 - 34,819,931	UniSTS
RH 3.4 Map	8	286.2	UniSTS
Cytogenetic Map	8	q21	UniSTS

BF394891

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	32,894,130 - 32,894,332 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	35,721,222 - 35,721,423	NCBI	Rnor6.0
Rnor_5.0	8	35,751,377 - 35,751,578	UniSTS	Rnor5.0
RGSC_v3.4	8	34,329,087 - 34,329,288	UniSTS	RGSC3.4
Celera	8	34,313,575 - 34,313,776	UniSTS
RH 3.4 Map	8	283.8	UniSTS
Cytogenetic Map	8	q21	UniSTS

BF400294

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	32,993,617 - 32,993,805 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	35,826,848 - 35,827,035	NCBI	Rnor6.0
Rnor_5.0	8	35,855,280 - 35,855,467	UniSTS	Rnor5.0
RGSC_v3.4	8	34,419,393 - 34,419,580	UniSTS	RGSC3.4
Celera	8	34,413,267 - 34,413,454	UniSTS
RH 3.4 Map	8	284.7	UniSTS
Cytogenetic Map	8	q21	UniSTS

BF399480

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,164,860 - 33,165,015 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	35,999,983 - 36,000,137	NCBI	Rnor6.0
Rnor_5.0	8	36,026,536 - 36,026,690	UniSTS	Rnor5.0
RGSC_v3.4	8	34,592,566 - 34,592,720	UniSTS	RGSC3.4
Celera	8	34,583,896 - 34,584,050	UniSTS
RH 3.4 Map	8	285.5	UniSTS
Cytogenetic Map	8	q21	UniSTS

AU047192

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,346,612 - 33,346,771 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	36,185,225 - 36,185,383	NCBI	Rnor6.0
Rnor_5.0	8	36,207,255 - 36,207,413	UniSTS	Rnor5.0
RGSC_v3.4	8	34,776,851 - 34,777,009	UniSTS	RGSC3.4
Celera	8	34,764,624 - 34,764,782	UniSTS
Cytogenetic Map	8	q21	UniSTS

RH138076

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,123,938 - 33,124,083 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	35,958,153 - 35,958,297	NCBI	Rnor6.0
Rnor_5.0	8	35,986,322 - 35,986,466	UniSTS	Rnor5.0
RGSC_v3.4	8	34,549,693 - 34,549,837	UniSTS	RGSC3.4
Celera	8	34,543,076 - 34,543,220	UniSTS
RH 3.4 Map	8	285.6	UniSTS
Cytogenetic Map	8	q21	UniSTS

RH139479

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	33,405,283 - 33,405,464 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	36,254,359 - 36,254,539	NCBI	Rnor6.0
Rnor_5.0	8	36,273,396 - 36,273,576	UniSTS	Rnor5.0
RGSC_v3.4	8	34,835,561 - 34,835,741	UniSTS	RGSC3.4
Celera	8	34,824,577 - 34,824,757	UniSTS
RH 3.4 Map	8	288.6	UniSTS
Cytogenetic Map	8	q21	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	2108128	47108128	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	2108128	47108128	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	2108128	47108128	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	2108128	47108128	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	7368076	52368076	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	7368076	52368076	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	7368076	52368076	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	8738677	53738677	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	9531047	119211942	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	10388439	55388439	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	10388439	55388439	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10938911	120496129	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	11373267	57541668	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	11373509	45712344	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	11373509	45712344	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	11448251	56448251	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	11448251	56448251	Rat
1558646	Swd5	Spike wave discharge measurement QTL 5	3.45	0.00036	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	8	17666555	62666555	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	20717592	65717592	Rat
631271	Lecl1	Lens clarity QTL 1		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	8	21464919	91140553	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	21813070	100873963	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	27841496	72841496	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	28168023	50708951	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	29867983	59908353	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	29867983	106526740	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	29867983	106526740	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	29867983	106526740	Rat
2303564	Gluco43	Glucose level QTL 43	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	30144800	75144800	Rat
2303572	Insul13	Insulin level QTL 13	2		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	8	30144800	75144800	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	30918112	58858224	Rat
1300146	Rf17	Renal function QTL 17	2.9		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	8	30918112	75918112	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	30918112	107206309	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	32201981	54065241	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	32201981	75971421	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	32888352	101374135	Rat
70206	Alc20	Alcohol consumption QTL 20	2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	8	33558660	44219353	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	33558660	46588570	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	33558660	62857995	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	33558660	65717592	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	33558660	65717592	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	33558660	65717592	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	33558660	65717592	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	33558660	65717592	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	33558660	65717592	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	33558660	89058369	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	33558660	89058369	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	33558660	89058369	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	33558660	89058369	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	33558660	109028082	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	33558660	109028082	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	33558660	109028082	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	33558764	113580387	Rat
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	35041414	80041414	Rat
1582222	Epfw2	Epididymal fat weight QTL 2	3.2	0.0005	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	8	35925594	80925594	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	463
Count of miRNA genes:	235
Interacting mature miRNAs:	290
Transcripts:	ENSRNOT00000013036
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									64		4
Low		11	18	2	16	2	1	1	10	34	36	11	1
Below cutoff	3	32	13	13	3	13	6	7		1	1		6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001048215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595617	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ902828	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000013036 ⟹ ENSRNOP00000013036

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	8	36,125,999 - 36,254,753 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000088046 ⟹ ENSRNOP00000073469

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	8	36,126,081 - 36,253,721 (+)	Ensembl

RefSeq Acc Id:

NM_001048215 ⟹ NP_001041680

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,865 - 33,405,680 (+)	NCBI
Rnor_6.0	8	35,692,525 - 36,254,755 (+)	NCBI
Rnor_5.0	8	35,722,596 - 36,273,792 (+)	NCBI
RGSC_v3.4	8	34,300,350 - 34,835,957 (+)	RGD
Celera	8	34,284,951 - 34,824,973 (+)	RGD

Sequence:

show sequence

AGCCGTGTGCCTGGGATACTAAGAGCCAGAGAATGGATCTGCTCCGAGTGGGGACATTGCTGAG
GATCCCGGCTTCCCGAGGTGGCTGAAAACAAGCATTTGGTTTCGGCTGCCTGCAGATACCTGGA
GTCACAGCGAGACCTAAGCGGACCGGAGGAGGGACAGACCGACTGACAGATAGATGGTCGGCGC
GAACCCAGGAGGACCGGCGGCGGAGGCTGAGCACCGCGAGCCCAGCCGCCGCTCTTGAAGAGAA
ACTAACTGCTCGCCCAAGTTGCCCCGCCGGCTGCCCGCGCGCTGAGGAATGAGACCTTTCCAGC
TGGATTTGCTCTTCCTCTGCTTCTTCCTTTTCAGTCAAGAGCTTGGCCTCCAGAGGAGAGGATG
CTGTCTGGTGCTGGGCTACATGGCCAAGGACAAGTTTCGGAGAATGAATGAAGGTCAAGTCTAC
TCCTTCAGCCAGCAACCCCAGGACCAAGTGGTGGTGTCAGGACAACCAGTGACTCTGCTGTGTG
CCATCCCTGAATATGATGGCTTCGTCCTGTGGATCAAAGATGGCTTGGCTCTAGGTGTAGGCAG
AGACCTCTCAAGCTACCCCCAGTACCTGGTGGTGGGGAACCACCTCTCAGGAGAGCATCACCTG
AAGATCCTGAGGGCTGAGCTGCAGGACGATGCTGTGTACGAGTGCCAGGCCATCCAGGCTGCCA
TCCGGTCCCGCCCTGCACGCCTTACAGTCCTGGTGCCACCAGATGACCCCATCATCCTAGGGGG
GCCTGTGATCAGCCTTCGGGCAGGGGATCCCCTCAACCTCACCTGCCATGCAGACAATGCCAAG
CCTGCAGCTTCCATCATCTGGCTACGCAAAGGAGAGGTCATCAATGGGGCCACCTACTCCAAGA
CCCTGCTTCGAGATGGCAAGCGTGAGAGCATCGTCAGCACACTCTTCATCTCCCCAGGGGACGT
AGAAAATGGGCAGAGCATTGTGTGCCGAGCCACCAACAAAGCCATCCCCGGAGGAAAGGAGACC
TCAGTCACCATAGACATCCAGCATCCACCACTTGTCAACTTGTCCGTAGAACCACAGCCGGTAT
TGGAGGACAATATCGTCACGTTCCACTGCTCTGCAAAGGCCAACCCAGCTGTCACCCAGTACAG
GTGGGCCAAACGGGGTCACATCATCAAGGAGGCATCTGGGGAGCTGTATAGGACCACCGTGGAC
TACACATACTTCTCAGAGCCTGTATCCTGCGAAGTGACCAATGCCTTGGGCAGCACCAACCTCA
GCCGCACAGTGGACGTGTACTTTGGCCCTCGAATGACCTCGGAGCCTCAGTCCCTGCTGGTAGA
TCTGGGCTCAGATGCTGTCTTCAGCTGTGCGTGGATCGGCAACCCATCTCTGACCATCGTGTGG
ATGAAACGAGGTTCTGGTGTGGTCCTGAGCAATGAAAAGACCCTAACCCTCAAATCTGTCCGCC
AAGAGGATGCCGGGAAGTACGTGTGCCGGGCTGTGGTGCCCCGGGTAGGAGCTGGGGAGAGAGA
GGTGACCTTGACTGTCAATGGACCCCCCATCATCTCCAGCACACAGACCCAGCATGCCCTCCAT
GGAGAGAAGGGCCAGATCAAATGCTTCATCCGGAGCACACCACCGCCTGACCGAATTGCCTGGT
CCTGGAAGGAGAATGTGCTGGAGTCGGGGACATCAGGGCGCTACACAGTGGAGACGGTGAACAC
CGAGGAGGGCGTCATCTCCACGCTGACCATTAGCAACATTGTGCGTGCTGACTTCCAGACCATA
TACAACTGTACAGCCTGGAACAGCTTCGGCTCTGACACAGAGATCATCCGACTCAAGGAACAAG
AGTCAGTGCCAATGGCCGTCATCATCGGGGTGGCCGTAGGAGCTGGCGTGGCCTTCCTCGTCCT
AATGGCAACCATTGTGGCCTTCTGCTGTGCCCGTTCCCAGAGAAATCTCAAAGGTGTTGTGTCA
GCCAAAAATGATATTCGAGTGGAGATTGTACACAAGGAGCCAGCTTCTGGTCGGGAGGCTGAGG
ACCACACCACCATCAAGCAGCTGATGATGGACCGGGGTGAATTCCAACAAGACTCCGTGCTGAA
GCAGCTGGAGGTCCTCAAAGAAGAGGAGAAGGAGTTTCAGAACCTGAAGGACCCCACCAACGGC
TACTACAGCGTCAACACCTTCAAAGAACACCATTCAACTCCAACCATCTCCCTGTCCAGCTGCC
AGCCAGACCTGCGTCCCACAGGCAAACAGCGAGTGCCCACAGGCATGTCCTTCACCAACATCTA
CAGCACCTTGAGCGGCCAGGGCCGCCTCTACGACTATGGACAGAGGTTTGTACTGGGCATGGGC
AGCTCTTCCATTGAGCTTTGTGAGCGGGAGTTTCAGAGGGGCTCCCTCAGCGACAGCAGCTCCT
TCCTAGACACGCAGTGTGACAGCAGCGTCAGCAGCAGCGGCAAACAAGATGGCTACGTGCAGTT
TGACAAGGCCAGCAAGGCTTCTGCCTCCTCTTCCCACCACTCCCAGTCCTCTTCCCAGAACTCC
GACCCCAGTCGACCCCTGCAGCGGCGGATGCAGACTCACGTCTGAGGACCGACCAAGCACTGTG
GTGGGGATGGGCCAAAGAGGAGGACAGGCCACATTCTCGTTCTCCAAGGACTGGGGCTATTTTG
CAGAGGACCCTAGAACTGGCCACCTCCGGGGTGGCCTCCAAGCACCTCTGTTAACACCTTCCTT
CGAAGCTCTGATCAAGCACAAATCTGGCTCCCGGGTGGAAAATGAAGAGAGTGCGGTTGAGTGC
ATAGTGCTCAGGGCCTTTGTCTCGTGCTCTTCCCTAAAGGTCCCTCAAACACCTTGTCCTCCCA
TGGGCATTAGTGGCAGCTAGAACTTTGCTTTTATGAAACTGCCGTCCACTTTGCTAGCTCCTCT
TGCTGCCCATAAGCCATCCCTGATGCCTGTATTCCTTACAGCCTTGGGGAACGGAGGACCTTTT
CCCAGCACTGAGCTGCTCCGGAGACCCCAGCTTCCCCACTGTGGGTAGCCCATACCACAGAGGC
TGGAGGCTGAGAAATGACCCCGACCAAAGGAGTATTTGCCTGGGAGCCCGCCCCCACTTTGTTT
GGTGTTTGTGTCTGTATTCTTGCAGTTCTGTTTTTGGACTTGGTGCCTCTGAGCTCGGTGGTGG
GACTGGCCCATCCGAATCTAGTGTCCTCAGAGCCGAGGAAGGGAAGGAGAGAATGTGAACGCCT
GGAGAACAGCTGACCCAACACACCCTGTGCCAGGCTGTGCAGTTCAGAGCCCTCGCCCCCAACC
CTCACACCCTGCTTCCTGTTCTCCCTTCCTTCCCACAGCACAATCAAGCTAATATGAGGAGTGT
GAGAACTTCTCCTGTCAGGGTTTGTTGAACAGTCACTGCAGAGTGCTTCCTGGGAGGTGTGGGT
TTGAGGTGGGGTGGGGCTGAAATCTAGGCTGGAGGATGAGACAGACTCTTTCAGCTAATGACCA
CAAAGAACAATGATCCATTCTCCTGTAGACAGGACTCTGTGTGCAAGAGGGACAGTTTTCTTCA
CCTCTCCCATCACTCCCCACTTAAGAATAAACGTTAGGGCCATTACCCACAAAAAA

hide sequence

RefSeq Acc Id:

XM_039081392 ⟹ XP_038937320

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,780 - 33,407,555 (+)	NCBI

RefSeq Acc Id:

XM_039081393 ⟹ XP_038937321

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,779 - 33,407,555 (+)	NCBI

RefSeq Acc Id:

XM_039081394 ⟹ XP_038937322

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,783 - 33,407,555 (+)	NCBI

RefSeq Acc Id:

XM_039081395 ⟹ XP_038937323

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,782 - 33,407,555 (+)	NCBI

RefSeq Acc Id:

XM_039081396 ⟹ XP_038937324

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,782 - 33,404,801 (+)	NCBI

RefSeq Acc Id:

XM_039081397 ⟹ XP_038937325

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	32,865,784 - 33,404,801 (+)	NCBI

RefSeq Acc Id:

XM_039081398 ⟹ XP_038937326

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	33,379,587 - 33,407,555 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001041680	(Get FASTA)	NCBI Sequence Viewer
	XP_038937320	(Get FASTA)	NCBI Sequence Viewer
	XP_038937321	(Get FASTA)	NCBI Sequence Viewer
	XP_038937322	(Get FASTA)	NCBI Sequence Viewer
	XP_038937323	(Get FASTA)	NCBI Sequence Viewer
	XP_038937324	(Get FASTA)	NCBI Sequence Viewer
	XP_038937325	(Get FASTA)	NCBI Sequence Viewer
	XP_038937326	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABI60897	(Get FASTA)	NCBI Sequence Viewer
	EDL83283	(Get FASTA)	NCBI Sequence Viewer
	EDL83284	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001041680 ⟸ NM_001048215
- Peptide Label:	precursor
- UniProtKB:	Q09GS6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRPFQLDLLFLCFFLFSQELGLQRRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQP VTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQ AIQAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVING ATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSV EPQPVLEDNIVTFHCSAKANPAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPVSCEVTNAL GSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLT LKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPP DRIAWSWKENVLESGTSGRYTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEII RLKEQESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRNLKGVVSAKNDIRVEIVHKEPAS GREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTI SLSSCQPDLRPTGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSL SDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV hide sequence

RefSeq Acc Id:

ENSRNOP00000073469 ⟸ ENSRNOT00000088046

RefSeq Acc Id:

ENSRNOP00000013036 ⟸ ENSRNOT00000013036

RefSeq Acc Id:	XP_038937321 ⟸ XM_039081393
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038937320 ⟸ XM_039081392
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038937323 ⟸ XM_039081395
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038937324 ⟸ XM_039081396
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038937322 ⟸ XM_039081394
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038937325 ⟸ XM_039081397
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038937326 ⟸ XM_039081398
- Peptide Label:	isoform X7

Protein Domains

Ig-like

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311382	AgrOrtholog
Ensembl Genes	ENSRNOG00000009772	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000013036	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000073469	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013036	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000088046	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
KEGG Report	rno:315546	UniProtKB/TrEMBL
NCBI Gene	315546	ENTREZGENE
Pfam	I-set	UniProtKB/TrEMBL
	Ig_2	UniProtKB/TrEMBL
PhenoGen	Kirrel3	PhenoGen
PROSITE	IG_LIKE	UniProtKB/TrEMBL
SMART	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A0G2K5L4_RAT	UniProtKB/TrEMBL
	E9PTD7_RAT	UniProtKB/TrEMBL
	Q09GS6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-06-21	Kirrel3	kirre like nephrin family adhesion molecule 3	Kirrel3	kin of IRRE like 3 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Kirrel3	kin of IRRE like 3 (Drosophila)	Kirrel3_predicted	kin of IRRE like 3 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Kirrel3_predicted	kin of IRRE like 3 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM