Kirrel3 (kirre like nephrin family adhesion molecule 3) - Rat Genome Database

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Gene: Kirrel3 (kirre like nephrin family adhesion molecule 3) Rattus norvegicus
Analyze
Symbol: Kirrel3
Name: kirre like nephrin family adhesion molecule 3
RGD ID: 1311382
Description: Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in hemopoiesis; homophilic cell adhesion via plasma membrane adhesion molecules; and nervous system development. Predicted to act upstream of or within glomerulus morphogenesis; inter-male aggressive behavior; and nervous system development. Predicted to be located in several cellular components, including axon; dendritic shaft; and synaptic vesicle. Predicted to be active in cell-cell junction and plasma membrane. Orthologous to human KIRREL3 (kirre like nephrin family adhesion molecule 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kin of IRRE like 3; kin of IRRE like 3 (Drosophila); kin of IRRE-like protein 3; LOC315546
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,123,692 - 41,663,528 (+)NCBIGRCr8
mRatBN7.2832,865,779 - 33,407,555 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl832,862,776 - 33,405,676 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx836,938,412 - 37,478,071 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0835,221,433 - 35,761,111 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0833,084,303 - 33,623,950 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0835,692,525 - 36,254,755 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,125,999 - 36,254,753 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0835,722,596 - 36,273,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4834,300,350 - 34,835,957 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1834,425,084 - 34,844,541 (+)NCBI
Celera834,284,951 - 34,824,973 (+)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kirrel3Ratautism spectrum disorder  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:25741868 and PMID:30504930
Kirrel3Ratautosomal dominant intellectual developmental disorder 4  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and autosomal dominant 4ClinVarPMID:19012874 and PMID:25741868
Kirrel3Ratchromosome 11 partial duplication syndrome  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Distal trisomy 11qClinVarPMID:25741868
Kirrel3RatDevelopmental Disabilities  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868
Kirrel3RatDevelopmental Disease  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental disorderClinVarPMID:25741868
Kirrel3RatDwarfism  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Short statureClinVarPMID:32581362
Kirrel3Ratintellectual disability  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868
Kirrel3RatJacobsen Syndrome  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Paris-Trousseau thrombocytopeniaClinVarPMID:32581362
Kirrel3Ratschizophrenia  ISOKIRREL3 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
1 to 9 of 9 rows

1 to 20 of 80 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kirrel3Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in increased expression of KIRREL3 mRNACTDPMID:26496021
Kirrel3Rat17beta-estradiol increases expressionISOKirrel3 (Mus musculus)6480464Estradiol results in increased expression of KIRREL3 mRNACTDPMID:39298647
Kirrel3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of KIRREL3 mRNACTDPMID:32109520
Kirrel3Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Kirrel3Rat2-palmitoylglycerol increases expressionISOKIRREL3 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of KIRREL3 mRNACTDPMID:37199045
Kirrel3Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOKirrel3 (Mus musculus)6480464tetrabromobisphenol A results in decreased expression of KIRREL3 mRNACTDPMID:25172293
Kirrel3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOKIRREL3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of KIRREL3 mRNACTDPMID:28628672
Kirrel3Rat4,4'-sulfonyldiphenol increases methylationISOKirrel3 (Mus musculus)6480464bisphenol S results in increased methylation of KIRREL3 exonCTDPMID:33297965
Kirrel3Rat4,4'-sulfonyldiphenol decreases methylationISOKIRREL3 (Homo sapiens)6480464bisphenol S results in decreased methylation of KIRREL3 geneCTDPMID:31601247
Kirrel3Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of KIRREL3 mRNACTDPMID:24780913
Kirrel3Rat8-Br-cAMP increases expressionISOKIRREL3 (Homo sapiens)64804648-Bromo Cyclic Adenosine Monophosphate results in increased expression of KIRREL3 mRNACTDPMID:22079614
Kirrel3Rataflatoxin B1 increases expressionISOKIRREL3 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of KIRREL3 mRNACTDPMID:22100608
Kirrel3Rataflatoxin B1 increases methylationISOKIRREL3 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of KIRREL3 intronCTDPMID:30157460
Kirrel3RatAflatoxin B2 alpha decreases methylationISOKIRREL3 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of KIRREL3 exon and aflatoxin B2 results in decreased methylation of KIRREL3 intronCTDPMID:30157460
Kirrel3Ratarsane multiple interactionsISOKIRREL3 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of KIRREL3 mRNACTDPMID:39836092
Kirrel3Ratarsenic atom multiple interactionsISOKIRREL3 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of KIRREL3 mRNACTDPMID:39836092
Kirrel3Ratatrazine increases expressionISOKIRREL3 (Homo sapiens)6480464Atrazine results in increased expression of KIRREL3 mRNACTDPMID:22378314
Kirrel3Ratbenzo[a]pyrene decreases methylationISOKIRREL3 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of KIRREL3 3' UTR and Benzo(a)pyrene results in decreased methylation of KIRREL3 exonCTDPMID:27901495
Kirrel3Ratbenzo[a]pyrene affects methylationISOKIRREL3 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of KIRREL3 exon and Benzo(a)pyrene affects the methylation of KIRREL3 intronCTDPMID:30157460
Kirrel3Ratbenzo[a]pyrene increases methylationISOKIRREL3 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of KIRREL3 promoterCTDPMID:27901495

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Biological Process
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kirrel3Ratcell-cell adhesion involved_inIBAFB:FBgn0000547 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kirrel3Ratglomerulus morphogenesis acts_upstream_of_or_withinIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratglomerulus morphogenesis acts_upstream_of_or_withinISOKirrel3 (Mus musculus)1624291MGI:5517690 PMID:23637329RGDPMID:23637329
Kirrel3Rathemopoiesis involved_inISOKirrel3 (Mus musculus)1624291 PMID:12665856RGDPMID:12665856
Kirrel3Rathemopoiesis involved_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Rathippocampus development involved_inISOKirrel3 (Mus musculus)1624291 PMID:26575286RGDPMID:26575286
Kirrel3Rathippocampus development involved_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Rathomophilic cell adhesion via plasma membrane adhesion molecules involved_inISOKirrel3 (Mus musculus)1624291 PMID:26575286RGDPMID:26575286
Kirrel3Rathomophilic cell adhesion via plasma membrane adhesion molecules involved_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratinter-male aggressive behavior acts_upstream_of_or_withinIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratinter-male aggressive behavior acts_upstream_of_or_withinISOKirrel3 (Mus musculus)1624291MGI:5517690 PMID:23637329RGDPMID:23637329
Kirrel3Ratneuron migration acts_upstream_of_or_withinISOKirrel3 (Mus musculus)1624291 PMID:21241806RGDPMID:21241806
Kirrel3Ratneuron migration acts_upstream_of_or_withinIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratneuron projection morphogenesis acts_upstream_of_or_withinISOKirrel3 (Mus musculus)1624291MGI:5517690 PMID:23637329RGDPMID:23637329
Kirrel3Ratneuron projection morphogenesis acts_upstream_of_or_withinIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratprincipal sensory nucleus of trigeminal nerve development acts_upstream_of_or_withinIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratprincipal sensory nucleus of trigeminal nerve development acts_upstream_of_or_withinISOKirrel3 (Mus musculus)1624291 PMID:21241806RGDPMID:21241806
Kirrel3Ratsynapse assembly involved_inISOKirrel3 (Mus musculus)1624291 PMID:26575286RGDPMID:26575286
Kirrel3Ratsynapse assembly involved_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratsynapse assembly involved_inIBAMGI:1914953 and PANTHER:PTN0026160281600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 20 of 20 rows

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kirrel3Rataxon located_inISOKirrel3 (Mus musculus)1624291 PMID:16874800 and PMID:26575286RGDPMID:16874800 and PMID:26575286
Kirrel3Rataxon located_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratcell-cell junction is_active_inIBAFB:FBgn0000547 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kirrel3Ratdendrite located_inISOKirrel3 (Mus musculus)1624291 PMID:26575286RGDPMID:26575286
Kirrel3Ratdendrite located_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratdendritic shaft located_inISOKirrel3 (Mus musculus)1624291 PMID:16874800RGDPMID:16874800
Kirrel3Ratdendritic shaft located_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratextracellular region located_inISOKirrel3 (Mus musculus)1624291 PMID:12665856RGDPMID:12665856
Kirrel3Ratextracellular region located_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Kirrel3Ratmembrane located_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratmembrane located_inISOKirrel3 (Mus musculus)1624291 PMID:12665856RGDPMID:12665856
Kirrel3Ratplasma membrane located_inIEAUniProtKB:Q8BR86 and ensembl:ENSMUSP000001402191600115GO_REF:0000107EnsemblGO_REF:0000107
Kirrel3Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Kirrel3Ratplasma membrane located_inISOKirrel3 (Mus musculus)1624291 PMID:12665856RGDPMID:12665856
Kirrel3Ratplasma membrane is_active_inIBAFB:FBgn0000547 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kirrel3Ratsynaptic vesicle part_ofISOKIRREL3 (Homo sapiens)1624291 PMID:25902260RGDPMID:25902260
Kirrel3Ratsynaptic vesicle part_ofIEAUniProtKB:Q8IZU9 and ensembl:ENSP000004354661600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 18 of 18 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kirrel3Ratcell adhesion molecule binding enablesIBAFB:FBgn0000547 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kirrel3Ratprotein binding enablesISOKIRREL3 (Homo sapiens)1624291UniProtKB:P05026 more ...RGDPMID:12424224 more ...
Kirrel3Ratprotein binding enablesISOKirrel3 (Mus musculus)1624291PR:O70589 more ...RGDPMID:16874800 more ...


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12665856   PMID:16874800   PMID:21241806   PMID:23637329   PMID:25902260   PMID:26575286  



Kirrel3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,123,692 - 41,663,528 (+)NCBIGRCr8
mRatBN7.2832,865,779 - 33,407,555 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl832,862,776 - 33,405,676 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx836,938,412 - 37,478,071 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0835,221,433 - 35,761,111 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0833,084,303 - 33,623,950 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0835,692,525 - 36,254,755 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,125,999 - 36,254,753 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0835,722,596 - 36,273,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4834,300,350 - 34,835,957 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1834,425,084 - 34,844,541 (+)NCBI
Celera834,284,951 - 34,824,973 (+)NCBICelera
Cytogenetic Map8q21NCBI
KIRREL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811126,423,358 - 127,000,870 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11126,423,358 - 127,003,460 (-)EnsemblGRCh38hg38GRCh38
GRCh3711126,293,253 - 126,870,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611125,799,613 - 126,375,701 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411125,799,684 - 126,375,615NCBI
Celera11123,459,514 - 124,037,646 (-)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11122,817,366 - 122,817,789 (-)NCBIHuRef
HuRef11122,238,286 - 122,410,924 (-)NCBIHuRef
CHM1_111126,179,676 - 126,756,915 (-)NCBICHM1_1
T2T-CHM13v2.011126,454,803 - 127,036,590 (-)NCBIT2T-CHM13v2.0
Kirrel3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39934,396,850 - 34,952,103 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl934,397,190 - 34,948,012 (+)EnsemblGRCm39 Ensembl
GRCm38934,485,853 - 35,040,807 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl934,485,894 - 35,036,716 (+)EnsemblGRCm38mm10GRCm38
MGSCv37934,296,316 - 34,843,889 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36934,238,296 - 34,785,975 (+)NCBIMGSCv36mm8
Celera931,740,583 - 32,293,826 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map918.97NCBI
Kirrel3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541227,428,360 - 27,991,321 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541227,428,360 - 27,994,458 (-)NCBIChiLan1.0ChiLan1.0
KIRREL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29127,105,851 - 127,690,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111128,213,408 - 128,798,315 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011121,236,962 - 121,821,806 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111125,146,563 - 125,726,452 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11125,146,563 - 125,723,504 (-)Ensemblpanpan1.1panPan2
KIRREL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.157,583,530 - 8,124,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl57,583,805 - 8,123,080 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha57,645,744 - 8,184,370 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.057,538,980 - 8,078,718 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl57,539,227 - 8,078,660 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.157,996,350 - 8,148,415 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.057,583,374 - 8,122,445 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.057,616,414 - 8,156,314 (+)NCBIUU_Cfam_GSD_1.0
Kirrel3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947108,652,952 - 108,687,285 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365725,239,573 - 5,796,368 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365725,763,098 - 5,797,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIRREL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl953,491,991 - 53,664,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1953,493,735 - 54,066,490 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2959,332,982 - 59,498,767 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KIRREL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11117,553,388 - 118,122,895 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1117,551,940 - 117,687,637 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660437,949,043 - 8,520,592 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kirrel3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624812562,308 - 1,154,934 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624812561,290 - 1,158,012 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Kirrel3
2736 total Variants

Predicted Target Of
Summary Value
Count of predictions:463
Count of miRNA genes:235
Interacting mature miRNAs:290
Transcripts:ENSRNOT00000013036
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat

1 to 10 of 51 rows
D8Rat100  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,343,218 - 33,343,426 (+)MAPPERmRatBN7.2
Rnor_6.0836,181,831 - 36,182,038NCBIRnor6.0
Rnor_5.0836,203,861 - 36,204,068UniSTSRnor5.0
RGSC_v3.4834,773,456 - 34,773,664RGDRGSC3.4
RGSC_v3.4834,773,457 - 34,773,664UniSTSRGSC3.4
RGSC_v3.1834,782,222 - 34,782,430RGD
Celera834,761,230 - 34,761,437UniSTS
FHH x ACI Map826.99RGD
FHH x ACI Map826.99UniSTS
Cytogenetic Map8q21UniSTS
D3Mco55  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8841,419,558 - 41,419,722 (+)Marker Load Pipeline
mRatBN7.2833,161,693 - 33,161,853 (+)MAPPERmRatBN7.2
Rnor_6.0835,996,819 - 35,996,978NCBIRnor6.0
Rnor_5.0836,023,372 - 36,023,531UniSTSRnor5.0
RGSC_v3.4834,589,399 - 34,589,558UniSTSRGSC3.4
RGSC_v3.43168,596,925 - 168,597,084UniSTSRGSC3.4
Celera834,580,747 - 34,580,906UniSTS
Cytogenetic Map8q21UniSTS
D8Got342  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2832,880,533 - 32,880,641 (+)MAPPERmRatBN7.2
Rnor_6.0835,707,396 - 35,707,503NCBIRnor6.0
Rnor_5.0835,737,551 - 35,737,658UniSTSRnor5.0
RGSC_v3.4834,315,019 - 34,315,126UniSTSRGSC3.4
Celera834,299,654 - 34,299,761UniSTS
Cytogenetic Map8q21UniSTS
BF386659  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,400,488 - 33,400,638 (+)MAPPERmRatBN7.2
Rnor_6.0836,249,564 - 36,249,713NCBIRnor6.0
Rnor_5.0836,268,601 - 36,268,750UniSTSRnor5.0
RGSC_v3.4834,830,766 - 34,830,915UniSTSRGSC3.4
Celera834,819,782 - 34,819,931UniSTS
RH 3.4 Map8286.2UniSTS
Cytogenetic Map8q21UniSTS
BF394891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2832,894,130 - 32,894,332 (+)MAPPERmRatBN7.2
Rnor_6.0835,721,222 - 35,721,423NCBIRnor6.0
Rnor_5.0835,751,377 - 35,751,578UniSTSRnor5.0
RGSC_v3.4834,329,087 - 34,329,288UniSTSRGSC3.4
Celera834,313,575 - 34,313,776UniSTS
RH 3.4 Map8283.8UniSTS
Cytogenetic Map8q21UniSTS
BF400294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2832,993,617 - 32,993,805 (+)MAPPERmRatBN7.2
Rnor_6.0835,826,848 - 35,827,035NCBIRnor6.0
Rnor_5.0835,855,280 - 35,855,467UniSTSRnor5.0
RGSC_v3.4834,419,393 - 34,419,580UniSTSRGSC3.4
Celera834,413,267 - 34,413,454UniSTS
RH 3.4 Map8284.7UniSTS
Cytogenetic Map8q21UniSTS
BF399480  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,164,860 - 33,165,015 (+)MAPPERmRatBN7.2
Rnor_6.0835,999,983 - 36,000,137NCBIRnor6.0
Rnor_5.0836,026,536 - 36,026,690UniSTSRnor5.0
RGSC_v3.4834,592,566 - 34,592,720UniSTSRGSC3.4
Celera834,583,896 - 34,584,050UniSTS
RH 3.4 Map8285.5UniSTS
Cytogenetic Map8q21UniSTS
AU047192  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,346,612 - 33,346,771 (+)MAPPERmRatBN7.2
Rnor_6.0836,185,225 - 36,185,383NCBIRnor6.0
Rnor_5.0836,207,255 - 36,207,413UniSTSRnor5.0
RGSC_v3.4834,776,851 - 34,777,009UniSTSRGSC3.4
Celera834,764,624 - 34,764,782UniSTS
Cytogenetic Map8q21UniSTS
RH138076  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,123,938 - 33,124,083 (+)MAPPERmRatBN7.2
Rnor_6.0835,958,153 - 35,958,297NCBIRnor6.0
Rnor_5.0835,986,322 - 35,986,466UniSTSRnor5.0
RGSC_v3.4834,549,693 - 34,549,837UniSTSRGSC3.4
Celera834,543,076 - 34,543,220UniSTS
RH 3.4 Map8285.6UniSTS
Cytogenetic Map8q21UniSTS
RH139479  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2833,405,283 - 33,405,464 (+)MAPPERmRatBN7.2
Rnor_6.0836,254,359 - 36,254,539NCBIRnor6.0
Rnor_5.0836,273,396 - 36,273,576UniSTSRnor5.0
RGSC_v3.4834,835,561 - 34,835,741UniSTSRGSC3.4
Celera834,824,577 - 34,824,757UniSTS
RH 3.4 Map8288.6UniSTS
Cytogenetic Map8q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 49 113 65 64 33 25 33 6 189 95 93 45 60 31


1 to 18 of 18 rows
RefSeq Transcripts NM_001048215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ902828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 18 of 18 rows

Ensembl Acc Id: ENSRNOT00000013036   ⟹   ENSRNOP00000013036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl832,866,169 - 33,405,676 (+)Ensembl
Rnor_6.0 Ensembl836,125,999 - 36,254,753 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088046   ⟹   ENSRNOP00000073469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl832,862,776 - 33,405,676 (+)Ensembl
Rnor_6.0 Ensembl836,126,081 - 36,253,721 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103546   ⟹   ENSRNOP00000080508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl832,862,776 - 33,405,676 (+)Ensembl
RefSeq Acc Id: NM_001048215   ⟹   NP_001041680
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,773 - 41,663,524 (+)NCBI
mRatBN7.2832,865,865 - 33,405,680 (+)NCBI
Rnor_6.0835,692,525 - 36,254,755 (+)NCBI
Rnor_5.0835,722,596 - 36,273,792 (+)NCBI
RGSC_v3.4834,300,350 - 34,835,957 (+)RGD
Celera834,284,951 - 34,824,973 (+)RGD
Sequence:
RefSeq Acc Id: XM_039081392   ⟹   XP_038937320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,693 - 41,663,528 (+)NCBI
mRatBN7.2832,865,780 - 33,407,555 (+)NCBI
RefSeq Acc Id: XM_039081393   ⟹   XP_038937321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,692 - 41,663,528 (+)NCBI
mRatBN7.2832,865,779 - 33,407,555 (+)NCBI
RefSeq Acc Id: XM_039081394   ⟹   XP_038937322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,695 - 41,663,528 (+)NCBI
mRatBN7.2832,865,783 - 33,407,555 (+)NCBI
RefSeq Acc Id: XM_039081395   ⟹   XP_038937323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,694 - 41,663,528 (+)NCBI
mRatBN7.2832,865,782 - 33,407,555 (+)NCBI
RefSeq Acc Id: XM_039081396   ⟹   XP_038937324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,694 - 41,663,528 (+)NCBI
mRatBN7.2832,865,782 - 33,404,801 (+)NCBI
RefSeq Acc Id: XM_039081397   ⟹   XP_038937325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,696 - 41,663,528 (+)NCBI
mRatBN7.2832,865,784 - 33,404,801 (+)NCBI
RefSeq Acc Id: XM_063265411   ⟹   XP_063121481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,123,694 - 41,663,528 (+)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_001041680   ⟸   NM_001048215
- Peptide Label: precursor
- UniProtKB: Q09GS6 (UniProtKB/TrEMBL),   E9PTD7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073469   ⟸   ENSRNOT00000088046
Ensembl Acc Id: ENSRNOP00000013036   ⟸   ENSRNOT00000013036
RefSeq Acc Id: XP_038937321   ⟸   XM_039081393
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937320   ⟸   XM_039081392
- Peptide Label: isoform X1
Ig-like

Name Modeler Protein Id AA Range Protein Structure
AF-E9PTD7-F1-model_v2 AlphaFold E9PTD7 1-761 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-31213 BioCyc
Ensembl Genes ENSRNOG00000009772 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013036.7 UniProtKB/TrEMBL
  ENSRNOT00000088046 ENTREZGENE
  ENSRNOT00000088046.2 UniProtKB/TrEMBL
  ENSRNOT00000103546 ENTREZGENE
  ENSRNOT00000103546.1 UniProtKB/TrEMBL
  ENSRNOT00000154206 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Cell_adhesion_signaling UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
KEGG Report rno:315546 UniProtKB/TrEMBL
NCBI Gene 315546 ENTREZGENE
PANTHER KIN OF IRRE-LIKE PROTEIN 3 UniProtKB/TrEMBL
  NEPHRIN UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PhenoGen Kirrel3 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009772 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0G2K5L4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQV3 ENTREZGENE, UniProtKB/TrEMBL
  E9PTD7 ENTREZGENE, UniProtKB/TrEMBL
  Q09GS6 ENTREZGENE, UniProtKB/TrEMBL
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-21 Kirrel3  kirre like nephrin family adhesion molecule 3  Kirrel3  kin of IRRE like 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Kirrel3  kin of IRRE like 3 (Drosophila)   Kirrel3_predicted  kin of IRRE like 3 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Kirrel3_predicted  kin of IRRE like 3 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED