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Gene: Il4r (interleukin 4 receptor) Rattus norvegicus
Symbol: Il4r
Name: interleukin 4 receptor
RGD ID: 2899
Description: Predicted to have cytokine receptor activity. Involved in several processes, including ovulation; response to estrogen; and response to odorant. Localizes to extracellular space. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; autoimmune disease (multiple); human immunodeficiency virus infectious disease; and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor); PARTICIPATES IN interleukin-4 signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Il4ra; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha
Homo sapiens (human) : IL4R (interleukin 4 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Il4ra (interleukin 4 receptor, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il4r (interleukin 4 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL4R (interleukin 4 receptor)
Canis lupus familiaris (dog) : IL4R (interleukin 4 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il4r (interleukin 4 receptor)
Sus scrofa (pig) : IL4R (interleukin 4 receptor)
Chlorocebus sabaeus (African green monkey) : IL4R (interleukin 4 receptor)
Heterocephalus glaber (naked mole-rat) : Il4r (interleukin 4 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01196,942,343 - 196,967,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1196,942,364 - 196,967,220 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01203,927,969 - 203,952,929 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,612,903 - 184,637,863 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11184,762,783 - 184,787,741 (+)NCBI
Celera1177,784,627 - 177,809,190 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il4r
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2899
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.