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Gene: Il4ra (interleukin 4 receptor, alpha) Mus musculus
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Symbol: Il4ra
Name: interleukin 4 receptor, alpha
RGD ID: 10798
Description: Predicted to have cytokine receptor activity. Involved in several processes, including positive regulation of cold-induced thermogenesis; positive regulation of myoblast fusion; and regulation of leukocyte activation. Predicted to localize to several cellular components, including centriolar satellite; extracellular space; and nucleoplasm. Is expressed in several structures, including adrenal medulla; early conceptus; hemolymphoid system; medulla oblongata basal plate mantle layer; and reproductive system. Used to study asthma. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; human immunodeficiency virus infectious disease; multiple sclerosis (multiple); and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor); PARTICIPATES IN interleukin-4 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD124; I; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Il4r; interleukin-4 receptor subunit alpha; MGC118473
Orthologs:
Homo sapiens (human) : IL4R (interleukin 4 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il4r (interleukin 4 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il4r (interleukin 4 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL4R (interleukin 4 receptor)
Canis lupus familiaris (dog) : IL4R (interleukin 4 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il4r (interleukin 4 receptor)
Sus scrofa (pig) : IL4R (interleukin 4 receptor)
Chlorocebus sabaeus (African green monkey) : IL4R (interleukin 4 receptor)
Heterocephalus glaber (naked mole-rat) : Il4r (interleukin 4 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl7125,552,120 - 125,579,474 (+)EnsemblGRCm38mm10GRCm38
GRCm387125,552,271 - 125,579,474 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377132,695,796 - 132,722,988 (+)NCBIGRCm37mm9NCBIm37
MGSCv367125,343,387 - 125,369,113 (+)NCBImm8
Celera7125,410,962 - 125,438,138 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map768.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Il4ra
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10798
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.