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GENE - TERM ANNOTATION REPORT

RGD ID: 10798
Species: Mus musculus
RGD Object: Gene
Symbol: Il4ra
Name: interleukin 4 receptor, alpha
Acc ID: DOID:9006041
Term: Osteoarthritis, Hip
Definition: Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion.
Definition Source(s): MESH:D015207
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4rano_associationISOIL4R (Homo sapiens)10402784RGDDNA:missense mutations:cds:p.S411L, p.S727A (rs1805013, rs1805016) (human) 
Il4rasusceptibilityISOIL4R (Homo sapiens)10402782RGDDNA:SNPs:multiple 
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