Snrpb2 (small nuclear ribonucleoprotein polypeptide B2)

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Gene: Snrpb2 (small nuclear ribonucleoprotein polypeptide B2) Rattus norvegicus

Analyze

Symbol:

Snrpb2

Name:

small nuclear ribonucleoprotein polypeptide B2

RGD ID:

1310194

Description:

Enables snRNP binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of small nuclear ribonucleoprotein complex. Human ortholog(s) of this gene implicated in connective tissue disease. Orthologous to human SNRPB2 (small nuclear ribonucleoprotein polypeptide B2); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; finasteride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC362223; small nuclear ribonucleoprotein polypeptide B''; U2 small nuclear ribonucleoprotein B; U2 small nuclear ribonucleoprotein B''

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	130,399,239 - 130,408,821 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	130,399,248 - 130,408,812 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	134,305,346 - 134,314,827 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	142,889,384 - 142,898,865 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	140,592,551 - 140,602,032 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	137,138,082 - 137,147,575 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	137,137,980 - 137,147,575 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	143,580,454 - 143,589,947 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	131,416,677 - 131,426,007 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	131,322,233 - 131,331,711 (+)	NCBI
Celera	3	129,321,277 - 129,330,597 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

connective tissue disease (ISO)

disease of cellular proliferation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-tribromophenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carmustine (ISO)

CGP 52608 (ISO)

copper atom (ISO)

copper(0) (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (ISO)

disulfiram (ISO)

ethanol (ISO)

finasteride (EXP)

flutamide (EXP)

genistein (EXP)

gentamycin (EXP)

gold atom (ISO)

gold(0) (ISO)

hydralazine (ISO)

indometacin (ISO)

ivermectin (ISO)

methylmercury chloride (ISO)

nickel sulfate (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pinosylvin (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tolcapone (EXP)

trans-pinosylvin (ISO)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

mRNA splicing, via spliceosome (IBA,ISO)

Cellular Component

catalytic step 2 spliceosome (ISO)

cytoplasmic ribonucleoprotein granule (IEA,ISO)

fibrillar center (IEA,ISO)

nuclear speck (IEA,ISO)

nucleus (ISO)

small nuclear ribonucleoprotein complex (IDA)

spliceosomal complex (ISO)

U1 snRNP (IBA)

U2 snRNP (ISO)

U2-type catalytic step 2 spliceosome (ISO)

U2-type precatalytic spliceosome (ISO)

Molecular Function

protein binding (IPI,ISO)

snRNP binding (IDA)

U1 snRNA binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.	Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2.	The U2 small nuclear ribonucleoprotein particle as an autoantigen. Analysis with sera from patients with overlap syndromes.	Craft J, etal., J Clin Invest. 1988 Jun;81(6):1716-24.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	A novel 40S multi-snRNP complex isolated from rat liver nuclei.	Guialis A, etal., Nucleic Acids Res. 1991 Jan 25;19(2):287-96.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.	Rozanov DV, etal., Cancer Res. 2008 Jun 1;68(11):4086-96. doi: 10.1158/0008-5472.CAN-07-6458.

Additional References at PubMed

PMID:2951739	PMID:9731529	PMID:11991638	PMID:12477932	PMID:28076346	PMID:28781166	PMID:30361391

Genomics

Comparative Map Data

Snrpb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	130,399,239 - 130,408,821 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	130,399,248 - 130,408,812 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	134,305,346 - 134,314,827 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	142,889,384 - 142,898,865 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	140,592,551 - 140,602,032 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	137,138,082 - 137,147,575 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	137,137,980 - 137,147,575 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	143,580,454 - 143,589,947 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	131,416,677 - 131,426,007 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	131,322,233 - 131,331,711 (+)	NCBI
Celera	3	129,321,277 - 129,330,597 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

SNRPB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	16,730,026 - 16,742,564 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	20	16,729,961 - 16,742,564 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	16,710,671 - 16,723,209 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	16,658,629 - 16,670,037 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	16,658,628 - 16,670,037	NCBI
Celera	20	16,785,672 - 16,797,480 (+)	NCBI		Celera
Cytogenetic Map	20	p12.1	NCBI
HuRef	20	16,673,454 - 16,685,262 (+)	NCBI		HuRef
CHM1_1	20	16,710,624 - 16,722,432 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	16,781,147 - 16,793,686 (+)	NCBI		T2T-CHM13v2.0

Snrpb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	142,904,989 - 142,913,972 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	142,904,959 - 142,914,773 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	143,063,069 - 143,072,052 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	143,063,039 - 143,072,853 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	142,888,805 - 142,897,788 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	142,754,510 - 142,763,493 (+)	NCBI		MGSCv36	mm8
Celera	2	144,238,085 - 144,247,080 (+)	NCBI		Celera
Cytogenetic Map	2	G1	NCBI

Snrpb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	25,879,983 - 25,890,707 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	25,880,013 - 25,889,295 (+)	NCBI	ChiLan1.0	ChiLan1.0

SNRPB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	20	16,670,823 - 16,682,418 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	16,670,826 - 16,682,418 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	20	16,690,562 - 16,701,964 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SNRPB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	6,106,217 - 6,117,369 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	6,106,217 - 6,117,369 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	5,972,930 - 5,984,084 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	6,512,414 - 6,523,916 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	6,512,769 - 6,523,916 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	6,121,887 - 6,133,032 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	6,218,271 - 6,229,422 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	6,494,619 - 6,505,772 (-)	NCBI		UU_Cfam_GSD_1.0

Snrpb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	154,864,984 - 154,874,634 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936485	3,296,350 - 3,305,985 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SNRPB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	25,363,167 - 25,373,281 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	25,363,107 - 25,373,289 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	97,022,361 - 97,023,045 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SNRPB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	45,654,264 - 45,666,073 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	45,654,285 - 45,667,736 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	6,037,211 - 6,049,622 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Snrpb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	17,892,964 - 17,902,321 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	17,892,908 - 17,902,321 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Snrpb2
74 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	17
Count of miRNA genes:	14
Interacting mature miRNAs:	17
Transcripts:	ENSRNOT00000006900
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	112287552	135181505	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	3	115638168	135181505	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	3	115638168	135181505	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	121056165	145956249	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	121056165	157309487	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat

Markers in Region

RH45368

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	130,401,544 - 130,401,673 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	137,140,354 - 137,140,482	NCBI	Rnor6.0
Rnor_5.0	3	143,582,726 - 143,582,854	UniSTS	Rnor5.0
RGSC_v3.4	3	131,418,945 - 131,419,073	UniSTS	RGSC3.4
Celera	3	129,323,543 - 129,323,671	UniSTS
Cytogenetic Map	3	q41	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	10	74	35	41	11	8
Low								1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105470	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000006900 ⟹ ENSRNOP00000006900

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	130,399,258 - 130,408,809 (+)	Ensembl
Rnor_6.0 Ensembl	3	137,137,980 - 137,147,575 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097908 ⟹ ENSRNOP00000083310

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	130,399,248 - 130,408,812 (+)	Ensembl

RefSeq Acc Id:

NM_001108592 ⟹ NP_001102062

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	130,399,280 - 130,408,810 (+)	NCBI
Rnor_6.0	3	137,138,082 - 137,147,566 (+)	NCBI
Rnor_5.0	3	143,580,454 - 143,589,947 (+)	NCBI
RGSC_v3.4	3	131,416,677 - 131,426,007 (+)	RGD
Celera	3	129,321,277 - 129,330,597 (+)	RGD

Sequence:

show sequence

AGCTTCAAGCGGACCGCGCCGGCTTCAGGCTACTTGAAGAGTTTTACCCAAACATGGATATCAG
ACCAAATCACACGATTTATATCAACAACATGAATGACAAAATTAAAAAAGAAGAATTGAAGAGA
TCCCTGTATGCCCTGTTTTCTCAGTTTGGACATGTGGTAGATATTGTGGCTTTAAAGACCATGA
AGATGAGAGGGCAGGCTTTTGTTATATTTAAGGAACTGGGCTCATCCACAAATGCTTTGAGACA
GTTACAAGGATTTCCATTTTATGGTAAACCAATGAGAATTCAGTACGCAAAAACAGATTCCGAT
ATAATATCTAAAATGCGTGGTACTTTCGCTGACAAGGAAAAGAAAAAGGAAAAGAAGAAAGCTA
AAACCATGGAACAGGCTGCAGCAGCTGCAAACAAGAAGCCTGGTCAGGGAACACCAAATTCAGC
TAATACTCAAGGAAATGCAGCACCAAATCCTCAGGTCCCTGATTACCCTCCAAACTATATCCTG
TTCCTTAATAACTTACCAGAAGAGACGAATGAGATGATGTTATCCATGTTGTTCAACCAGTTCC
CTGGTTTCAAGGAAGTTCGCCTGGTCCCGGGGAGACATGATATTGCGTTTGTAGAATTTGAAAA
TGATGGGCAGGCTGGAGCAGCCAGAGATGCTCTGCAAGGGTTTAAGATCACACCATCCCATGCC
ATGAAGATTACCTATGCCAAGAAGTAACACGGGGAGTGCCAGTTTTAAAGGACTTGGTATTATT
TATAGCTTTTGTTTTAATTATATTCAGTCAAGTTGTTTGAAATGGTTGGAAGTGAAGGTGAAGT
TTTGGAAAAAGAGTCACCTAATTTTTTTTAGTTTTGGTGAACTATGAAATACAAAGCCTTAATT
TTGTACAATAAACTTTTATTTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039105469 ⟹ XP_038961397

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	130,399,456 - 130,408,821 (+)	NCBI

RefSeq Acc Id:

XM_039105470 ⟹ XP_038961398

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	130,399,239 - 130,408,819 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102062	(Get FASTA)	NCBI Sequence Viewer
	XP_038961397	(Get FASTA)	NCBI Sequence Viewer
	XP_038961398	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68760	(Get FASTA)	NCBI Sequence Viewer
	EDL95190	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001102062 ⟸ NM_001108592

- UniProtKB:

B5DEQ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTN
ALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTMEQAAAAANKKPGQGT
PNSANTQGNAAPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFV
EFENDGQAGAARDALQGFKITPSHAMKITYAKK

hide sequence

RefSeq Acc Id:

ENSRNOP00000006900 ⟸ ENSRNOT00000006900

RefSeq Acc Id:	XP_038961398 ⟸ XM_039105470
- Peptide Label:	isoform X2
- UniProtKB:	B5DEQ4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961397 ⟸ XM_039105469
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000083310 ⟸ ENSRNOT00000097908

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DEQ4-F1-model_v2	AlphaFold	B5DEQ4	1-225	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692476

Promoter ID:

EPDNEW_R3000

Type:

initiation region

Name:

Snrpb2_1

Description:

small nuclear ribonucleoprotein polypeptide B2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	137,138,050 - 137,138,110	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310194	AgrOrtholog
BioCyc Gene	G2FUF-47633	BioCyc
Ensembl Genes	ENSRNOG00000004967	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006900	ENTREZGENE
	ENSRNOP00000006900.4	UniProtKB/TrEMBL
	ENSRNOP00000083310	ENTREZGENE
	ENSRNOP00000083310.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006900	ENTREZGENE
	ENSRNOT00000006900.8	UniProtKB/TrEMBL
	ENSRNOT00000097908	ENTREZGENE
	ENSRNOT00000097908.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RRM_RNP1	UniProtKB/TrEMBL
	U2B''_RRM1	UniProtKB/TrEMBL
	U2B''_RRM2	UniProtKB/TrEMBL
KEGG Report	rno:362223	UniProtKB/TrEMBL
NCBI Gene	362223	ENTREZGENE
Pfam	RRM_1	UniProtKB/TrEMBL
PhenoGen	Snrpb2	PhenoGen
PROSITE	RRM	UniProtKB/TrEMBL
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A8I6GAM2_RAT	UniProtKB/TrEMBL
	B5DEQ4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-13	Snrpb2	small nuclear ribonucleoprotein polypeptide B2	Snrpb2	small nuclear ribonucleoprotein polypeptide B''	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-18	Snrpb2	small nuclear ribonucleoprotein polypeptide B''	Snrpb2	U2 small nuclear ribonucleoprotein B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Snrpb2	U2 small nuclear ribonucleoprotein B	Snrpb2_predicted	U2 small nuclear ribonucleoprotein B (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Snrpb2_predicted	U2 small nuclear ribonucleoprotein B (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)