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Gene: Zc3hav1 (zinc finger CCCH-type containing, antiviral 1) Rattus norvegicus

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Symbol:

Zc3hav1

Name:

zinc finger CCCH-type containing, antiviral 1

RGD ID:

628694

Description:

Enables RNA binding activity and identical protein binding activity. Involved in several processes, including cellular response to virus; negative regulation of viral genome replication; and regulation of defense response to virus by host. Predicted to be located in cytosol. Orthologous to human ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; CCCH-type zinc finger antiviral protein (Zap); inactive Poly [ADP-ribose] polymerase 13; PARP13; rZAP; Zap; zinc finger antiviral protein; zinc finger CCCH type, antiviral 1; zinc finger CCCH-type antiviral protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	67,979,055 - 68,029,353 (-)	NCBI		GRCr8
mRatBN7.2	4	67,012,129 - 67,062,428 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	67,012,185 - 67,062,428 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	71,953,735 - 72,004,161 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	67,874,809 - 67,925,232 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	66,272,523 - 66,322,954 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	66,012,111 - 66,062,160 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	66,011,915 - 66,062,089 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	65,826,564 - 65,876,469 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	65,854,471 - 65,894,691 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	66,131,238 - 66,170,505 (-)	NCBI
Celera	4	62,042,340 - 62,082,577 (-)	NCBI		Celera
Cytogenetic Map	4	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pleomorphic xanthoastrocytoma (ISO)

RASopathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dimethoxyphenol (ISO)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

acetaldehyde (ISO)

acetamide (EXP)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clozapine (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

Dibutyl phosphate (ISO)

dichloromethane (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

elesclomol (ISO)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

ethylbenzene (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

indometacin (ISO)

irinotecan (ISO)

ivermectin (ISO)

leflunomide (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

Nutlin-3 (ISO)

o-xylene (ISO)

paracetamol (EXP)

PCB138 (EXP)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium dodecyl sulfate (ISO)

sunitinib (ISO)

temozolomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

Triptolide (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to exogenous dsRNA (ISO)

cellular response to virus (IMP)

defense response to virus (IEA)

immune system process (IEA)

innate immune response (IEA)

negative regulation of viral genome replication (IDA,IEA,ISO)

positive regulation of canonical NF-kappaB signal transduction (ISO)

positive regulation of interferon-alpha production (ISO)

positive regulation of interferon-beta production (ISO)

positive regulation of mRNA catabolic process (IDA,IEA,ISO)

positive regulation of RIG-I signaling pathway (ISO)

positive regulation of type I interferon production (ISO)

protein poly-ADP-ribosylation (ISO)

regulation of defense response to virus by host (IDA)

response to virus (IDA,IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA,ISO)

late endosome (IEA)

lysosome (IEA)

nucleus (IEA)

Molecular Function

identical protein binding (IPI)

metal ion binding (IEA)

NAD+ binding (ISO)

NAD+ poly-ADP-ribosyltransferase activity (IEA,ISO)

NAD+-protein mono-ADP-ribosyltransferase activity (ISO,ISS)

protein binding (IPI,ISO)

RNA binding (IDA,IEA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ADP-ribosylation pathway, mono and poly-ribosylation (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.	Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2.	p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein.	Chen G, etal., Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4352-7. doi: 10.1073/pnas.0712276105. Epub 2008 Mar 11.
3.	Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.	Chen S, etal., Nat Struct Mol Biol. 2012 Mar 11;19(4):430-5. doi: 10.1038/nsmb.2243.
4.	Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein.	Gao G, etal., Science 2002 Sep 6;297(5587):1703-6.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA.	Guo X, etal., Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):151-6. Epub 2006 Dec 21.
7.	ZAP is a CRM1-dependent nucleocytoplasmic shuttling protein.	Liu L, etal., Biochem Biophys Res Commun. 2004 Aug 27;321(3):517-23. doi: 10.1016/j.bbrc.2004.06.174.
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Mutagenesis analysis of the zinc-finger antiviral protein.	Wang X, etal., Retrovirology. 2010 Mar 13;7:19. doi: 10.1186/1742-4690-7-19.
11.	DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein.	Ye P, etal., Protein Cell. 2010 Oct;1(10):956-64. doi: 10.1007/s13238-010-0117-8. Epub 2010 Nov 9.
12.	Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation.	Zhu Y, etal., Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15834-9. doi: 10.1073/pnas.1101676108. Epub 2011 Aug 29.

Additional References at PubMed

PMID:12477932	PMID:14557641	PMID:21102435	PMID:22514281	PMID:22658674	PMID:22681889	PMID:23776219	PMID:25043379	PMID:25468996	PMID:25635049	PMID:30361391

Genomics

Comparative Map Data

Zc3hav1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	67,979,055 - 68,029,353 (-)	NCBI		GRCr8
mRatBN7.2	4	67,012,129 - 67,062,428 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	67,012,185 - 67,062,428 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	71,953,735 - 72,004,161 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	67,874,809 - 67,925,232 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	66,272,523 - 66,322,954 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	66,012,111 - 66,062,160 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	66,011,915 - 66,062,089 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	65,826,564 - 65,876,469 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	65,854,471 - 65,894,691 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	66,131,238 - 66,170,505 (-)	NCBI
Celera	4	62,042,340 - 62,082,577 (-)	NCBI		Celera
Cytogenetic Map	4	q23	NCBI

ZC3HAV1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	139,043,515 - 139,109,720 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	139,043,515 - 139,132,122 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	138,728,261 - 138,794,466 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	138,378,806 - 138,445,005 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	138,202,339 - 138,251,720	NCBI
Celera	7	133,466,056 - 133,532,619 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI
HuRef	7	133,038,132 - 133,104,319 (-)	NCBI		HuRef
CHM1_1	7	138,662,006 - 138,728,215 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	140,356,423 - 140,423,001 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	138,072,485 - 138,139,025 (-)	NCBI

Zc3hav1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	38,282,221 - 38,332,859 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	38,282,221 - 38,331,538 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	38,305,286 - 38,355,352 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	38,305,286 - 38,354,603 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	38,260,497 - 38,304,603 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	38,245,280 - 38,284,211 (-)	NCBI		MGSCv36	mm8
Celera	6	38,291,163 - 38,335,321 (-)	NCBI		Celera
Cytogenetic Map	6	B1	NCBI
cM Map	6	17.72	NCBI

Zc3hav1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955494	3,926,413 - 3,983,736 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955494	3,925,478 - 3,985,469 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZC3HAV1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	175,857,527 - 175,946,268 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	27,867,781 - 27,956,522 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	131,002,580 - 131,068,513 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	143,489,750 - 143,555,438 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	143,489,750 - 143,555,438 (-)	Ensembl	panpan1.1		panPan2

ZC3HAV1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	9,598,339 - 9,660,540 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	9,598,405 - 9,664,569 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	10,439,855 - 10,502,406 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	9,518,059 - 9,580,757 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	9,518,076 - 9,584,948 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	9,468,490 - 9,529,717 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	9,311,534 - 9,372,833 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	9,383,612 - 9,446,209 (+)	NCBI		UU_Cfam_GSD_1.0

Zc3hav1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	15,840,508 - 15,898,271 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936592	3,321,454 - 3,358,983 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936592	3,321,564 - 3,379,015 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZC3HAV1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	10,531,897 - 10,588,832 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	10,529,805 - 10,588,913 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	11,012,930 - 11,067,469 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZC3HAV1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	107,770,270 - 107,808,575 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666072	4,600,101 - 4,678,883 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zc3hav1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624765	19,439,923 - 19,509,186 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624765	19,441,299 - 19,509,468 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Zc3hav1
229 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	682
Count of miRNA genes:	303
Interacting mature miRNAs:	388
Transcripts:	ENSRNOT00000018782
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	103194791	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	40433388	85433388	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	43457976	88457976	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	26775591	168368347	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	57486946	102486946	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114705	78881294	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	115089733	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	26907285	75585128	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	39505275	73892441	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	40433414	85433414	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	29494195	81006281	Rat
2317577	Eae24	Experimental allergic encephalomyelitis QTL 24			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	4	66993185	72752834	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	26907285	75585128	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
2300179	Bmd50	Bone mineral density QTL 50	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	4	60928534	105928534	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	62933508	114921294	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	56647873	149491524	Rat
1578657	Bss12	Bone structure and strength QTL 12	8.9		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	4	60220938	105220938	Rat
1578658	Bss13	Bone structure and strength QTL 13	8		femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	4	60220938	105220938	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	56647776	78882945	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	56647776	78882945	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	56647776	78882945	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	56647776	78882945	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	39524264	74726312	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	57114432	81266970	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	59948935	154902892	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	10814170	91360527	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	65882107	96130297	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	36303261	103194984	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	34430484	82490359	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	62933508	82490359	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5214602	78882945	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	62277855	128289560	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	62879517	107879517	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	58432133	92991462	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	56698790	126192555	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114432	91360801	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	64528739	157573521	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	62933269	87483707	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	32583980	114627242	Rat
631671	Iddm11	Insulin dependent diabetes mellitus QTL 11	3.6	0.0012	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	58635877	78886137	Rat

Markers in Region

BQ205634

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	67,029,260 - 67,029,410 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	66,029,239 - 66,029,388	NCBI	Rnor6.0
Rnor_5.0	4	65,843,613 - 65,843,762	UniSTS	Rnor5.0
RGSC_v3.4	4	65,861,547 - 65,861,696	UniSTS	RGSC3.4
Celera	4	62,049,433 - 62,049,582	UniSTS
RH 3.4 Map	4	833.93	UniSTS
Cytogenetic Map	4	q22	UniSTS

RH132456

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	4	68,029,566 - 68,029,769 (+)	Marker Load Pipeline
mRatBN7.2	4	67,062,641 - 67,062,844 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	66,062,331 - 66,062,533	NCBI	Rnor6.0
Rnor_5.0	4	65,876,705 - 65,876,907	UniSTS	Rnor5.0
RGSC_v3.4	4	65,894,927 - 65,895,129	UniSTS	RGSC3.4
Celera	4	62,082,813 - 62,083,015	UniSTS
RH 3.4 Map	4	419.51	UniSTS
Cytogenetic Map	4	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001398725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_173045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF521008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC131842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018782 ⟹ ENSRNOP00000018782

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	67,012,185 - 67,062,428 (-)	Ensembl
Rnor_6.0 Ensembl	4	66,011,915 - 66,062,089 (-)	Ensembl

RefSeq Acc Id:

NM_001398725 ⟹ NP_001385654

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	67,979,055 - 68,029,353 (-)	NCBI
mRatBN7.2	4	67,012,129 - 67,062,428 (-)	NCBI

RefSeq Acc Id:

NM_173045 ⟹ NP_766633

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	67,989,078 - 68,029,353 (-)	NCBI
mRatBN7.2	4	67,022,152 - 67,062,428 (-)	NCBI
Rnor_6.0	4	66,022,132 - 66,062,095 (-)	NCBI
Rnor_5.0	4	65,826,564 - 65,876,469 (-)	NCBI
RGSC_v3.4	4	65,854,471 - 65,894,691 (-)	RGD
Celera	4	62,042,340 - 62,082,577 (-)	RGD

Sequence:

show sequence

GTAGCAGCCTCGCAGTCCGGAGCTCCGGGGACCTCACGTCTAGCCTGGAACCGAGGGTGCCGCG
GCACGGCGGACCTGCCGGCGAAAGGTTGCTTGCTTCCCATTCGCTCTCCCGCGCGGCTAACTTT
AAATCTGACCCCGGGACCTGGCCGGTGAGGTCGGGCCTCGCGACGCCACCGCCGGAGTTGGAAA
GCGAAACCGCTCTGCGCTAGGAGCGGCACCGCCCGCGTCCGCCCCTGGGGCCGCGTGTAAGTTT
CGATTCTCCGTAAAGCCGAGTCCCGCGCAGCGGCCCGAGCGGCGGCAGCCATAGCGCGCCATGG
CAGATCCCGGGGTATGCTGTTTCATCACCAAGATCCTGTGCGCCCACGGGGGCCGTATGACCCT
GGAGGAACTGCTGGGTGAGATCAGGCTCCCCGAGGCGCAGCTCTACGAGCTGCTGGAGACGGCG
GGGCCCGATCGCTTCGTGCTATTGGAGACTGGAGGCCAGGCCGGGATCACTCGGTCTGTAGTGG
CTACTACTCGAGCCCGCGTCTGCCGTCGGAAGTACTGCCAGAGACCCTGCGACAGCCTGCACCT
CTGCAAGCTTAATCTGCTCGGCCGGTGCCACTATGCACAGTCTCAGCGGAACCTCTGCAAATAT
TCTCACGATGTTCTCTCGGAACAGAACTTCCAGATCCTGAAGAATCATGAGCTCTCTGGGCTTA
ACCAAGAGGAGCTAGCTTGCCTCCTGGTCCAAAGCGACCCTTTTTTCCTGCCCGAGATATGCAA
GAGTTACAAAGGAGAGGGCCGAAAACAGACCTGCGGGCAGCCACAGCCATGCGAGAGACTCCAC
ATCTGTGAGCACTTCACCCGGGGCAACTGCAGTTACCTCAACTGTCTCAGGTCTCACAACCTGA
TGGACAGAAAGGTGTTGACCATCATGAGGGAGCACGGGCTGAGTCCTGATGTGGTCCAGAACAT
CCAGGACATCTGCAACAACAAACACGCCAGGAGGAACCCGCCTGGCACGAGAGCTGCCCATCCA
CACCGCAGAGGCGGCGCACACAGAGACAGAAGCAAAAGCAGAGACCGCTTCCTTCACAACAGTC
TAGAATTTCTCTCACCTGTTGTCTCACCTCTGGGATCTGGTCCGCCTAGCCCAGATGTCACCAG
CTGTAAAGATTCCCTGGAGGATGTGTCTGTGGATGTCACCCAGAAGTTCAAGTACTTGGGGACG
CACGACCGTGCGCAGCTCTCCCCAGTCTCATCTAAGGCTGCTGGTGTTCAAGGACCCAGTCAAA
TGAGAGCAAGCCAGGAGTTTTCAGAGGATGGGAATCTAGATGACATATTTTCTAGGAATCGTTC
TGATTCATCATCAAGTCGAGCCTCCGCTGCCAAGGTGGCACAAAGAAATGAAGCTGTGGCCATG
AAAATGGGCATGGAGGTCAAGGGCAAGAAGGAGGCTCCAGACATCGATCGGGTCCCATTTTTAA
ATAGTTATATTGATGGGGTGACCATGGAAAAAGCATCGGTCTCAGGAATTCCAGGCAAAAAGTT
CACAGCCAATGATCTGGAAAATTTGCTATTACTTAACGACACTTGGAAGAATGTGGCTAAGCCC
CAGGATCTGCAGACCACAGGCAGAATCACTGACAGTGGCCAAGACAAGGCATTCCTGCAGAGTA
AATATGGAGGAAACCCAGTGTGGGCAAGTGCATCCACCCATAATGCCCCAAATGGCTCTAGTCA
AATTATGGATGAAACTCCTAATGTCTCTAAAAGTAGTACCAGTGGTTTTGCCATAAAACCAGCA
ATTGCTGGAGGAAAAGAAGCAGTCTATTCTGGAGTTCAGAGTCCGAGAAGCCAGGTCCTAGCTA
TGCCTGGGGAGACTACTACCCCTGTACAGAGCAACAGGCTGCCTCAGTCGCCTCTGTCTTCCTC
AAGCCACAGAGCTGCAGCCTCTGGGAGCCCTGGCAAGAACTCCACCCATACCTCTGTGAGCCCA
GCCATCGAGTCTTCAAGGATGACATCAGACCCCGATGAGTATCTCCTACGCTACATCCTAAATC
CTTTATTTAGGATGGATAATCATGGCCCGAAGGAAATCTGTCAGGACCATCTGTACAAGGGCTG
TCAACAGAGCCACTGCGACAGGAGTCACTTCCATCTGCCCTACCGGTGGCAGATGTTCGTATAT
ACCACTTGGAGGGACTTCCAGGACATGGAGTCTATCGAACAGGCCTATTGTGATCCCCACGTTG
AACTCATTTTGATAGAAAACCATCAGATCAATTTCCAGAAAATGACCTGTGACTCCTACCCCAT
CCGACGCCTCTCCACTCCCTCATATGAGGAAAAGCCACTTAGTGCTGTCTTCGCCACCAAGTGG
ATTTGGTATTGGAAGAATGAATTTAATGAATATATCCAGTATGGGAATGAGAGCCCAGGCCACA
CCAGCTCTGACATCAACTCTGCGTACCTGGAGTCTTTCTTCCAGTCTTGTCCCAGGGGAGTTTT
GCCATTCCAGGCTGGTTCACAGAAGTACGAGTTAAGCTTTCAAGGGATGATTCAGACAAATATA
GCTTCCAAGACTCAAAGGCATGTTGTCAGAAGGCCAGTATTTGTTTCTTCGAACGATGTGGAGC
AGAAGAGAAGAGCTCCAGAGTAAGTGTTCTGAAGCTGTTAGCTCTGGCCATGATCTTGCTGCGT
CGTGCTGCATCATGCATCTGGATTCTGTGTTGTTGGGAAGTTCCTGCCTCTGTCTCACTGCAGT
TTCTATTTGATTTACCTATGAGTAAGGAAGATTGTTAAGCAATGTGGCATAACTGAAAGTTTCC
TGGACCAGGGGGCCAAGGGGTGCAGGCACTTGGTTAAGCTTTGTGTAATAGATATAAGGTTTGG
ATTTTGGGTATAGGGTGGGAAGGATACTATATCATTAAACCAGCATTTGCTTTTAACTTACAGG
GTATTTTAGCAGCTCTCCATACTCTGGGTCACACTTGCTCCAGCTGTTACTGACTGGATCAAGG
GGTGTGCCGGCAAATACACTGGGTTTTTGTTTTGCTGAGGGTCCTCTTTCTGTCTTTGGTTGTG
CTGTGAGGGCAGGGGGCTGAGAAAAAGGCTTAAGCTAGCAGCCTGGTGAAGAGCTGGAGAAAGA
TCAAGTTGGCTAAAGGCATTGGTTTTAATTTTAATTGATTTCTAATCATTGTACCCATGGGGCA
TTTCAAGGTGGGTTTTGCTGTGGGGAATTCATTGTAACTTGCCTATCTGCTATGAAACTCAGTA
AAGTCTCATTGTTCACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NR_174122

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	67,979,055 - 68,029,353 (-)	NCBI
mRatBN7.2	4	67,012,129 - 67,062,428 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001385654	(Get FASTA)	NCBI Sequence Viewer
	NP_766633	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI31843	(Get FASTA)	NCBI Sequence Viewer
	AAM75358	(Get FASTA)	NCBI Sequence Viewer
	EDM15355	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018782
GenBank Protein	Q8K3Y6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_766633 ⟸ NM_173045
- Peptide Label:	isoform 2
- UniProtKB:	Q8K3Y6 (UniProtKB/Swiss-Prot), A2RRT6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGITRSV VATTRARVCRRKYCQRPCDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQILKNHELSG LNQEELACLLVQSDPFFLPEICKSYKGEGRKQTCGQPQPCERLHICEHFTRGNCSYLNCLRSHN LMDRKVLTIMREHGLSPDVVQNIQDICNNKHARRNPPGTRAAHPHRRGGAHRDRSKSRDRFLHN SLEFLSPVVSPLGSGPPSPDVTSCKDSLEDVSVDVTQKFKYLGTHDRAQLSPVSSKAAGVQGPS QMRASQEFSEDGNLDDIFSRNRSDSSSSRASAAKVAQRNEAVAMKMGMEVKGKKEAPDIDRVPF LNSYIDGVTMEKASVSGIPGKKFTANDLENLLLLNDTWKNVAKPQDLQTTGRITDSGQDKAFLQ SKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSSTSGFAIKPAIAGGKEAVYSGVQSPRSQVL AMPGETTTPVQSNRLPQSPLSSSSHRAAASGSPGKNSTHTSVSPAIESSRMTSDPDEYLLRYIL NPLFRMDNHGPKEICQDHLYKGCQQSHCDRSHFHLPYRWQMFVYTTWRDFQDMESIEQAYCDPH VELILIENHQINFQKMTCDSYPIRRLSTPSYEEKPLSAVFATKWIWYWKNEFNEYIQYGNESPG HTSSDINSAYLESFFQSCPRGVLPFQAGSQKYELSFQGMIQTNIASKTQRHVVRRPVFVSSNDV EQKRRAPE hide sequence

Ensembl Acc Id:

ENSRNOP00000018782 ⟸ ENSRNOT00000018782

RefSeq Acc Id:	NP_001385654 ⟸ NM_001398725
- Peptide Label:	isoform 1
- UniProtKB:	A6IER7 (UniProtKB/TrEMBL), F7F0B1 (UniProtKB/TrEMBL)

Protein Domains

C3H1-type PARP catalytic WWE

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8K3Y6-F1-model_v2	AlphaFold	Q8K3Y6	1-776	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692967

Promoter ID:

EPDNEW_R3492

Type:

multiple initiation site

Name:

Zc3hav1_2

Description:

zinc finger CCCH-type containing, antiviral 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R3493

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	66,061,822 - 66,061,882	EPDNEW

RGD ID:

13692968

Promoter ID:

EPDNEW_R3493

Type:

initiation region

Name:

Zc3hav1_1

Description:

zinc finger CCCH-type containing, antiviral 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R3492

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	66,062,117 - 66,062,177	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628694	AgrOrtholog
BioCyc Gene	G2FUF-45214	BioCyc
Ensembl Genes	ENSRNOG00000013948	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000018782	ENTREZGENE
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
	3.30.720.50	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:8372019	IMAGE-MGC_LOAD
InterPro	ARTD-AVP	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WWE-dom	UniProtKB/Swiss-Prot
	WWE_dom_sf	UniProtKB/Swiss-Prot
	ZAP_HTH	UniProtKB/Swiss-Prot
	Znf-CCCH_8	UniProtKB/Swiss-Prot
	Znf_CCCH	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:156580	IMAGE-MGC_LOAD
NCBI Gene	252832	ENTREZGENE
PANTHER	POLY [ADP-RIBOSE] POLYMERASE	UniProtKB/Swiss-Prot
	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	HTH_53	UniProtKB/Swiss-Prot
	WWE	UniProtKB/Swiss-Prot
	zf-CCCH_8	UniProtKB/Swiss-Prot
PhenoGen	Zc3hav1	PhenoGen
PROSITE	WWE	UniProtKB/Swiss-Prot
	ZF_C3H1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013948	RatGTEx
Superfamily-SCOP	SSF117839	UniProtKB/Swiss-Prot
UniProt	A2RRT6	ENTREZGENE, UniProtKB/TrEMBL
	A6IER7	ENTREZGENE, UniProtKB/TrEMBL
	F7F0B1	ENTREZGENE, UniProtKB/TrEMBL
	Q8K3Y6	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Zc3hav1	zinc finger CCCH-type containing, antiviral 1	Zc3hav1	zinc finger CCCH type, antiviral 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-08	Zc3hav1	zinc finger CCCH type, antiviral 1	Zap	CCCH-type zinc finger antiviral protein (Zap)	Symbol and Name updated	1299863	APPROVED
2003-02-27	Zap	CCCH-type zinc finger antiviral protein (Zap)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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