Fam3c (FAM3 metabolism regulating signaling molecule C) - Rat Genome Database

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Gene: Fam3c (FAM3 metabolism regulating signaling molecule C) Rattus norvegicus
Analyze
Symbol: Fam3c
Name: FAM3 metabolism regulating signaling molecule C
RGD ID: 735193
Description: Predicted to enable cytokine activity. Predicted to act upstream of or within several processes, including intracellular signaling cassette; keratinocyte proliferation; and neutrophil differentiation. Predicted to be located in Golgi apparatus. Predicted to be active in extracellular space. Orthologous to human FAM3C (FAM3 metabolism regulating signaling molecule C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FAM3C-like protein; family with sequence similarity 3, member C; interleukin-like EMT inducer; LOC312159
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8451,805,686 - 51,853,030 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl451,805,703 - 51,853,030 (-)EnsemblGRCr8
mRatBN7.2450,839,929 - 50,887,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl450,838,818 - 50,888,078 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx455,825,466 - 55,872,830 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0451,746,545 - 51,793,901 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0450,172,124 - 50,219,707 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0449,388,962 - 49,439,892 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl449,387,989 - 49,439,867 (-)Ensemblrn6Rnor6.0
Rnor_5.0449,179,381 - 49,231,971 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4448,628,905 - 48,676,252 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera446,046,371 - 46,093,722 (-)NCBICelera
RGSC_v3.1448,859,478 - 48,906,826 (-)NCBI
Cytogenetic Map4q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
dibutyl phthalate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
fipronil  (EXP)
flutamide  (EXP)
furfural  (ISO)
glafenine  (EXP)
glyphosate  (EXP)
GSK-J4  (ISO)
irinotecan  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel sulfate  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
potassium chromate  (ISO)
quercitrin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
thapsigargin  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Cloning, expression, and initial characterization of a novel cytokine-like gene family. Zhu Y, etal., Genomics 2002 Aug;80(2):144-50.
Additional References at PubMed
PMID:23376485   PMID:23533145   PMID:24006456  


Genomics

Comparative Map Data
Fam3c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8451,805,686 - 51,853,030 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl451,805,703 - 51,853,030 (-)EnsemblGRCr8
mRatBN7.2450,839,929 - 50,887,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl450,838,818 - 50,888,078 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx455,825,466 - 55,872,830 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0451,746,545 - 51,793,901 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0450,172,124 - 50,219,707 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0449,388,962 - 49,439,892 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl449,387,989 - 49,439,867 (-)Ensemblrn6Rnor6.0
Rnor_5.0449,179,381 - 49,231,971 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4448,628,905 - 48,676,252 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera446,046,371 - 46,093,722 (-)NCBICelera
RGSC_v3.1448,859,478 - 48,906,826 (-)NCBI
Cytogenetic Map4q22NCBI
FAM3C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387121,348,878 - 121,396,396 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7121,348,851 - 121,396,364 (-)Ensemblhg38GRCh38
GRCh377120,988,932 - 121,036,362 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367120,776,141 - 120,823,658 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347120,582,857 - 120,630,292NCBI
Celera7115,798,102 - 115,845,614 (-)NCBICelera
Cytogenetic Map7q31.31NCBI
HuRef7115,352,144 - 115,399,666 (-)NCBIHuRef
CHM1_17120,922,224 - 120,969,734 (-)NCBICHM1_1
T2T-CHM13v2.07122,664,194 - 122,711,727 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27120,383,656 - 120,431,153 (-)NCBI
Fam3c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39622,306,519 - 22,356,080 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl622,306,519 - 22,356,242 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38622,306,520 - 22,356,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl622,306,520 - 22,356,243 (-)Ensemblmm10GRCm38
MGSCv37622,256,522 - 22,306,081 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36622,256,523 - 22,306,082 (-)NCBIMGSCv36mm8
Celera622,360,644 - 22,410,200 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map69.24NCBI
Fam3c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,083,719 - 3,128,610 (-)Ensembl
ChiLan1.0NW_0049554793,086,380 - 3,128,612 (-)NCBIChiLan1.0ChiLan1.0
FAM3C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26158,222,632 - 158,270,292 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1710,234,045 - 10,280,463 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07113,361,718 - 113,409,292 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17126,048,752 - 126,096,440 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7126,048,752 - 126,096,440 (-)EnsemblpanPan2panpan1.1
FAM3C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,407,920 - 59,447,257 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,410,012 - 59,447,258 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1458,822,333 - 58,874,998 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01459,441,840 - 59,494,504 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1459,441,846 - 59,494,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11459,535,226 - 59,587,846 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01459,160,036 - 59,212,872 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01459,538,294 - 59,591,126 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fam3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511848,355,297 - 48,396,837 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366053,807,032 - 3,848,634 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366053,807,089 - 3,848,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM3C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1825,569,536 - 25,612,458 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11825,569,356 - 25,612,072 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21827,174,036 - 27,216,644 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAM3C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12190,166,576 - 90,214,387 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2190,166,520 - 90,214,384 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604213,347,749 - 13,395,379 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam3c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478314,690,948 - 14,739,458 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478314,690,954 - 14,741,027 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Fam3c
395 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:286
Count of miRNA genes:183
Interacting mature miRNAs:213
Transcripts:ENSRNOT00000007886
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
10450825Scl78Serum cholesterol level QTL 783.70.01blood VLDL cholesterol amount (VT:0005144)blood low density lipoprotein cholesterol level (CMO:0000053)44917811657114705Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
10450821Scl77Serum cholesterol level QTL 774.10.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)44917811657114705Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
10450818Scl76Serum cholesterol level QTL 763.60.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)44917811657114705Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41794699962946999Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000077889   ⟹   ENSRNOP00000069031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl451,805,703 - 51,853,030 (-)Ensembl
mRatBN7.2 Ensembl450,839,921 - 50,887,296 (-)Ensembl
Rnor_6.0 Ensembl449,389,501 - 49,422,824 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090583   ⟹   ENSRNOP00000075071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl450,838,818 - 50,888,078 (-)Ensembl
Rnor_6.0 Ensembl449,387,989 - 49,439,867 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158097   ⟹   ENSRNOP00000100186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl451,805,703 - 51,851,859 (-)Ensembl
RefSeq Acc Id: NM_198771   ⟹   NP_942066
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8451,805,686 - 51,853,030 (-)NCBI
mRatBN7.2450,839,929 - 50,887,276 (-)NCBI
Rnor_6.0449,388,962 - 49,439,892 (-)NCBI
Rnor_5.0449,179,381 - 49,231,971 (-)NCBI
RGSC_v3.4448,628,905 - 48,676,252 (-)RGD
Celera446,046,371 - 46,093,722 (-)RGD
Sequence:
RefSeq Acc Id: NP_942066   ⟸   NM_198771
- Peptide Label: precursor
- UniProtKB: Q810F4 (UniProtKB/Swiss-Prot),   A6IE65 (UniProtKB/TrEMBL),   A0A0G2JUB0 (UniProtKB/TrEMBL),   A6IE64 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075071   ⟸   ENSRNOT00000090583
Ensembl Acc Id: ENSRNOP00000069031   ⟸   ENSRNOT00000077889
Ensembl Acc Id: ENSRNOP00000100186   ⟸   ENSRNOT00000158097
Protein Domains
GG-type lectin   ILEI/PANDER

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q810F4-F1-model_v2 AlphaFold Q810F4 1-227 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692900
Promoter ID:EPDNEW_R3425
Type:initiation region
Name:Fam3c_1
Description:family with sequence similarity 3, member C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0449,439,950 - 49,440,010EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735193 AgrOrtholog
BioCyc Gene G2FUF-45505 BioCyc
Ensembl Genes ENSRNOG00000060349 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000077889 ENTREZGENE
InterPro FAM3 UniProtKB/Swiss-Prot
  ILEI/PANDER_dom UniProtKB/Swiss-Prot
  ILEI_FAM3C UniProtKB/Swiss-Prot
KEGG Report rno:312159 UniProtKB/Swiss-Prot
NCBI Gene 312159 ENTREZGENE
PANTHER PTHR14592 UniProtKB/Swiss-Prot
Pfam ILEI UniProtKB/Swiss-Prot
PhenoGen Fam3c PhenoGen
PROSITE GG_LECTIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060349 RatGTEx
UniProt A0A0G2JUB0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2RAP9_RAT UniProtKB/TrEMBL
  A6IE63_RAT UniProtKB/TrEMBL
  A6IE64 ENTREZGENE, UniProtKB/TrEMBL
  A6IE65 ENTREZGENE, UniProtKB/TrEMBL
  A6IE66_RAT UniProtKB/TrEMBL
  A6IE67_RAT UniProtKB/TrEMBL
  A6IE68_RAT UniProtKB/TrEMBL
  FAM3C_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-04 Fam3c  FAM3 metabolism regulating signaling molecule C  Fam3c  family with sequence similarity 3, member C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Fam3c  family with sequence similarity 3, member C  LOC312159  FAM3C-like protein  Symbol and Name updated 1299863 APPROVED