![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fam3c | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM3C mRNA | CTD | PMID:22079256 | Fam3c | Rat | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | FAM3C (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to FAM3C protein | CTD | PMID:32991956 | Fam3c | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Fam3c (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of FAM3C mRNA | CTD | PMID:17555576 | Fam3c | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of FAM3C mRNA | CTD | PMID:31388691 | Fam3c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM3C mRNA | CTD | PMID:17101203 | Fam3c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FAM3C mRNA | CTD | PMID:34747641 | Fam3c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM3C mRNA | CTD | PMID:32109520 | Fam3c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM3C mRNA | CTD | PMID:26290441 | Fam3c | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [Furaldehyde co-treated with pyrogallol 1,3-dimethyl ether] results in increased expression of FAM3C protein; [Sodium Chloride more ... | CTD | PMID:38598786 | Fam3c | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | bisphenol S results in decreased expression of FAM3C mRNA | CTD | PMID:33297965 | Fam3c | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | Fenretinide results in increased expression of FAM3C mRNA | CTD | PMID:28973697 | Fam3c | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | Fenretinide results in decreased expression of FAM3C mRNA | CTD | PMID:28973697 | Fam3c | Rat | 9-cis-retinoic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Alitretinoin results in increased expression of FAM3C mRNA | CTD | PMID:15982314 | Fam3c | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FAM3C mRNA | CTD | PMID:31881176 | Fam3c | Rat | acrylamide | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | Acrylamide results in increased expression of FAM3C mRNA | CTD | PMID:30807115 | Fam3c | Rat | all-trans-4-oxoretinoic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | 4-oxoretinoic acid results in increased expression of FAM3C mRNA | CTD | PMID:15982314 | Fam3c | Rat | all-trans-retinoic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tretinoin metabolite results in increased expression of FAM3C mRNA; Tretinoin results in increased expression of more ... | CTD | PMID:15982314|PMID:21934132 | Fam3c | Rat | all-trans-retinoic acid | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of FAM3C mRNA | CTD | PMID:33167477 | Fam3c | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FAM3C mRNA | CTD | PMID:16483693 | Fam3c | Rat | aristolochic acid A | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FAM3C mRNA | CTD | PMID:33212167 | Fam3c | Rat | avobenzone | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | avobenzone results in increased expression of FAM3C mRNA | CTD | PMID:31016361 | Fam3c | Rat | benzo[a]pyrene | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FAM3C mRNA | CTD | PMID:20064835 | Fam3c | Rat | benzo[a]pyrene | decreases methylation | ISO | FAM3C (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM3C promoter | CTD | PMID:27901495 | Fam3c | Rat | benzo[a]pyrene | decreases methylation | ISO | Fam3c (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM3C intron | CTD | PMID:27901495 | Fam3c | Rat | benzo[a]pyrene | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of FAM3C mRNA | CTD | PMID:22228805 | Fam3c | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of FAM3C mRNA | CTD | PMID:34319233 | Fam3c | Rat | bisphenol A | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | bisphenol A results in decreased expression of FAM3C mRNA | CTD | PMID:26063408|PMID:33221593 | Fam3c | Rat | bisphenol A | decreases methylation | ISO | FAM3C (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of FAM3C gene | CTD | PMID:31601247 | Fam3c | Rat | bisphenol A | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of FAM3C mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:29275510|PMID:37567409 | Fam3c | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FAM3C mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Fam3c | Rat | bisphenol F | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | bisphenol F results in increased expression of FAM3C mRNA | CTD | PMID:38685157 | Fam3c | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of FAM3C mRNA | CTD | PMID:33453195 | Fam3c | Rat | chlorpyrifos | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of FAM3C mRNA | CTD | PMID:37019170 | Fam3c | Rat | chromium(6+) | affects expression | ISO | Fam3c (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of FAM3C mRNA | CTD | PMID:28472532 | Fam3c | Rat | cisplatin | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FAM3C mRNA | CTD | PMID:27594783 | Fam3c | Rat | dibutyl phthalate | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of FAM3C mRNA | CTD | PMID:21266533 | Fam3c | Rat | diuron | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Diuron results in decreased expression of FAM3C mRNA | CTD | PMID:35967413 | Fam3c | Rat | dorsomorphin | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Fam3c | Rat | epoxiconazole | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of FAM3C mRNA | CTD | PMID:35436446 | Fam3c | Rat | fenthion | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | Fenthion results in decreased expression of FAM3C mRNA | CTD | PMID:34813904 | Fam3c | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of FAM3C mRNA | CTD | PMID:34044035 | Fam3c | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of FAM3C mRNA | CTD | PMID:24136188 | Fam3c | Rat | furfural | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [Furaldehyde co-treated with pyrogallol 1,3-dimethyl ether] results in increased expression of FAM3C protein; [Sodium Chloride more ... | CTD | PMID:38598786 | Fam3c | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of FAM3C mRNA | CTD | PMID:24136188 | Fam3c | Rat | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of FAM3C gene | CTD | PMID:35440735 | Fam3c | Rat | GSK-J4 | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | GSK-J4 results in increased expression of FAM3C mRNA | CTD | PMID:29301935 | Fam3c | Rat | irinotecan | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of FAM3C mRNA | CTD | PMID:18927307 | Fam3c | Rat | isotretinoin | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Isotretinoin results in increased expression of FAM3C mRNA | CTD | PMID:15982314 | Fam3c | Rat | isotretinoin | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of FAM3C mRNA | CTD | PMID:20436886 | Fam3c | Rat | ivermectin | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of FAM3C protein | CTD | PMID:32959892 | Fam3c | Rat | lead(0) | affects expression | ISO | FAM3C (Homo sapiens) | 6480464 | Lead affects the expression of FAM3C mRNA | CTD | PMID:28903495 | Fam3c | Rat | methidathion | decreases expression | ISO | Fam3c (Mus musculus) | 6480464 | methidathion results in decreased expression of FAM3C mRNA | CTD | PMID:34813904 | Fam3c | Rat | methylmercury chloride | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of FAM3C mRNA | CTD | PMID:26272509 | Fam3c | Rat | methylparaben | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | methylparaben results in decreased expression of FAM3C mRNA | CTD | PMID:31745603 | Fam3c | Rat | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of FAM3C mRNA | CTD | PMID:20360939 | Fam3c | Rat | N-nitrosodiethylamine | increases expression | ISO | Fam3c (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of FAM3C mRNA | CTD | PMID:24535843 | Fam3c | Rat | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of FAM3C mRNA | CTD | PMID:19638242 | Fam3c | Rat | nickel sulfate | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of FAM3C mRNA | CTD | PMID:22714537 | Fam3c | Rat | nitrates | multiple interactions | ISO | Fam3c (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of FAM3C more ... | CTD | PMID:35964746 | Fam3c | Rat | okadaic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of FAM3C mRNA | CTD | PMID:38832940 | Fam3c | Rat | paclitaxel | affects response to substance | ISO | FAM3C (Homo sapiens) | 6480464 | FAM3C protein affects the susceptibility to Paclitaxel | CTD | PMID:16217747 | Fam3c | Rat | paracetamol | affects expression | ISO | Fam3c (Mus musculus) | 6480464 | Acetaminophen affects the expression of FAM3C mRNA | CTD | PMID:17562736 | Fam3c | Rat | paracetamol | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of FAM3C mRNA | CTD | PMID:29067470 | Fam3c | Rat | potassium chromate | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FAM3C mRNA | CTD | PMID:22079256 | Fam3c | Rat | potassium chromate | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM3C mRNA | CTD | PMID:22079256 | Fam3c | Rat | quercitrin | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | quercitrin results in increased expression of FAM3C mRNA | CTD | PMID:25193878 | Fam3c | Rat | SB 431542 | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of FAM3C more ... | CTD | PMID:27188386|PMID:37664457 | Fam3c | Rat | sodium arsenite | affects methylation | ISO | FAM3C (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of FAM3C gene | CTD | PMID:28589171 | Fam3c | Rat | sodium chloride | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of FAM3C protein; [Sodium Chloride co-treated more ... | CTD | PMID:38598786 | Fam3c | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of FAM3C mRNA | CTD | PMID:25993096 | Fam3c | Rat | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of FAM3C protein | CTD | PMID:35544339 | Fam3c | Rat | thimerosal | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Thimerosal results in increased expression of FAM3C mRNA | CTD | PMID:27188386 | Fam3c | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FAM3C mRNA | CTD | PMID:23411599 | Fam3c | Rat | titanium dioxide | decreases methylation | ISO | Fam3c (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FAM3C gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Fam3c | Rat | trichostatin A | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FAM3C mRNA | CTD | PMID:24935251|PMID:26272509 | Fam3c | Rat | trichostatin A | multiple interactions | ISO | FAM3C (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Fam3c | Rat | triphenyl phosphate | affects expression | ISO | FAM3C (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FAM3C mRNA | CTD | PMID:37042841 | Fam3c | Rat | tunicamycin | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of FAM3C mRNA | CTD | PMID:22378314 | Fam3c | Rat | uranium atom | affects expression | ISO | FAM3C (Homo sapiens) | 6480464 | Uranium affects the expression of FAM3C mRNA | CTD | PMID:15672453 | Fam3c | Rat | urethane | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Urethane results in increased expression of FAM3C mRNA | CTD | PMID:28818685 | Fam3c | Rat | valproic acid | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FAM3C mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251 | Fam3c | Rat | valproic acid | increases expression | ISO | FAM3C (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FAM3C mRNA | CTD | PMID:23179753|PMID:23527032|PMID:24935251|PMID:27188386|PMID:28001369 | Fam3c | Rat | valproic acid | decreases methylation | ISO | FAM3C (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of FAM3C gene | CTD | PMID:29154799 | Fam3c | Rat | vincaleukoblastine | affects response to substance | ISO | FAM3C (Homo sapiens) | 6480464 | FAM3C protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | Fam3c | Rat | vorinostat | decreases expression | ISO | FAM3C (Homo sapiens) | 6480464 | vorinostat results in decreased expression of FAM3C mRNA | CTD | PMID:27188386 | |