Ephb6 (Eph receptor B6) - Rat Genome Database

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Gene: Ephb6 (Eph receptor B6) Rattus norvegicus
Analyze
Symbol: Ephb6
Name: Eph receptor B6
RGD ID: 1306163
Description: Predicted to enable transmembrane-ephrin receptor activity. Predicted to be involved in axon guidance and central nervous system projection neuron axonogenesis. Predicted to act upstream of or within several processes, including activated T cell proliferation; positive regulation of T cell costimulation; and type IV hypersensitivity. Predicted to be located in cell surface. Predicted to be active in neuron projection. Orthologous to human EPHB6 (EPH receptor B6); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ephrin type-B receptor 6; LOC102554290; LOC312275; serine/arginine repetitive matrix protein 2-like; tyrosine-protein kinase-defective receptor EPH-6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2470,491,973 - 70,507,230 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl470,491,973 - 70,507,230 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx475,409,463 - 75,424,754 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0471,322,717 - 71,338,007 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0469,731,061 - 69,746,342 (+)NCBIRnor_WKY
Rnor_6.0470,903,253 - 70,918,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl470,903,253 - 70,918,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,690,323 - 135,705,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,316,600 - 69,331,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1469,593,119 - 69,607,982 (+)NCBI
Celera465,457,027 - 65,472,281 (+)NCBICelera
Cytogenetic Map4q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
malaria  (ISO)
myoepithelioma  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice. Mimche PN, etal., Hepatology. 2015 Sep;62(3):900-14. doi: 10.1002/hep.27792. Epub 2015 Apr 22.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15057822   PMID:15599401  


Genomics

Comparative Map Data
Ephb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2470,491,973 - 70,507,230 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl470,491,973 - 70,507,230 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx475,409,463 - 75,424,754 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0471,322,717 - 71,338,007 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0469,731,061 - 69,746,342 (+)NCBIRnor_WKY
Rnor_6.0470,903,253 - 70,918,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl470,903,253 - 70,918,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,690,323 - 135,705,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,316,600 - 69,331,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1469,593,119 - 69,607,982 (+)NCBI
Celera465,457,027 - 65,472,281 (+)NCBICelera
Cytogenetic Map4q23NCBI
EPHB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,855,076 - 142,871,093 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7142,855,061 - 142,871,094 (+)EnsemblGRCh38hg38GRCh38
GRCh377142,552,838 - 142,568,847 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,262,914 - 142,278,969 (+)NCBINCBI36Build 36hg18NCBI36
Build 347142,069,628 - 142,085,682NCBI
Celera7137,390,094 - 137,406,149 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,891,079 - 136,907,058 (+)NCBIHuRef
CHM1_17142,488,986 - 142,505,065 (+)NCBICHM1_1
T2T-CHM13v2.07144,210,901 - 144,226,909 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27141,954,640 - 141,970,711 (+)NCBI
Ephb6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39641,580,768 - 41,597,445 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl641,582,416 - 41,597,443 (+)EnsemblGRCm39 Ensembl
GRCm38641,603,834 - 41,620,509 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl641,605,482 - 41,620,509 (+)EnsemblGRCm38mm10GRCm38
MGSCv37641,555,481 - 41,570,506 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36641,535,175 - 41,550,109 (+)NCBIMGSCv36mm8
Celera641,558,073 - 41,573,098 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
Ephb6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955494812,855 - 820,475 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955494812,482 - 820,679 (+)NCBIChiLan1.0ChiLan1.0
EPHB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17147,337,558 - 147,353,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7147,337,558 - 147,353,575 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07134,845,936 - 134,862,114 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
EPHB6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,706,302 - 6,718,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,706,313 - 6,718,566 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0166,617,379 - 6,632,929 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,617,386 - 6,629,133 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,570,657 - 6,586,203 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,422,134 - 6,437,682 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,480,896 - 6,496,448 (-)NCBIUU_Cfam_GSD_1.0
Ephb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511812,558,265 - 12,573,314 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936527329,990 - 345,167 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936527330,034 - 345,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHB6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,346,565 - 7,389,504 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,346,793 - 7,419,859 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,652,270 - 7,659,953 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121111,742,236 - 111,750,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21111,742,268 - 111,752,179 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660728,457,010 - 8,474,045 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ephb6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480012,069,908 - 12,074,669 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480012,069,977 - 12,076,992 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ephb6
62 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:45
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000019720
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45664777678882945Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45664777678882945Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45664777678882945Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45664777678882945Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)457114432102114432Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711470578881294Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45863587778886137Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
2317577Eae24Experimental allergic encephalomyelitis QTL 24nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)46699318572752834Rat
2317577Eae24Experimental allergic encephalomyelitis QTL 24nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)46699318572752834Rat
2317577Eae24Experimental allergic encephalomyelitis QTL 24nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)46699318572752834Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat

Markers in Region
RH129621  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2470,507,017 - 70,507,219 (+)MAPPERmRatBN7.2
Rnor_6.0470,918,302 - 70,918,503NCBIRnor6.0
Rnor_5.04135,705,367 - 135,705,568UniSTSRnor5.0
RGSC_v3.4469,331,644 - 69,331,845UniSTSRGSC3.4
Celera465,472,069 - 65,472,270UniSTS
RH 3.4 Map4419.81UniSTS
Cytogenetic Map4q22UniSTS
UniSTS:495891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2470,500,134 - 70,500,958 (+)MAPPERmRatBN7.2
Rnor_6.0470,911,419 - 70,912,242NCBIRnor6.0
Rnor_5.04135,698,484 - 135,699,307UniSTSRnor5.0
RGSC_v3.4469,324,761 - 69,325,584UniSTSRGSC3.4
Celera465,465,186 - 65,466,009UniSTS
Cytogenetic Map4q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 16 8 60 26
Low 3 39 39 39 11 39 8 8 14 34 15 11 8
Below cutoff 4 2 2 2 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019720   ⟹   ENSRNOP00000019720
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl470,491,973 - 70,507,230 (+)Ensembl
Rnor_6.0 Ensembl470,903,253 - 70,918,514 (+)Ensembl
RefSeq Acc Id: NM_001107857   ⟹   NP_001101327
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2470,491,973 - 70,507,230 (+)NCBI
Rnor_6.0470,903,253 - 70,918,514 (+)NCBI
Rnor_5.04135,690,323 - 135,705,579 (+)NCBI
RGSC_v3.4469,316,600 - 69,331,856 (+)RGD
Celera465,457,027 - 65,472,281 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101327 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15483 (Get FASTA)   NCBI Sequence Viewer  
  P0C0K7 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001101327   ⟸   NM_001107857
- Peptide Label: precursor
- UniProtKB: P0C0K7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000019720   ⟸   ENSRNOT00000019720
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C0K7-F1-model_v2 AlphaFold P0C0K7 1-1013 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693002
Promoter ID:EPDNEW_R3525
Type:single initiation site
Name:Ephb6_1
Description:Eph receptor B6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0470,903,154 - 70,903,214EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306163 AgrOrtholog
BioCyc Gene G2FUF-45110 BioCyc
Ensembl Genes ENSRNOG00000014367 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000019720 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019720 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro Eph_TM UniProtKB/Swiss-Prot
  Ephrin_rcpt_lig-bd_dom UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr-kin_ephrin_A/B_rcpt-like UniProtKB/Swiss-Prot
  Tyr_kinase_ephrin_rcpt UniProtKB/Swiss-Prot
  Tyr_kinase_rcpt_V_CS UniProtKB/Swiss-Prot
KEGG Report rno:312275 UniProtKB/Swiss-Prot
NCBI Gene 312275 ENTREZGENE
Pfam EphA2_TM UniProtKB/Swiss-Prot
  Ephrin_lbd UniProtKB/Swiss-Prot
  Ephrin_rec_like UniProtKB/Swiss-Prot
  fn3 UniProtKB/Swiss-Prot
  Pkinase_Tyr UniProtKB/Swiss-Prot
  SAM_2 UniProtKB/Swiss-Prot
PhenoGen Ephb6 PhenoGen
PIRSF TyrPK_ephrin_receptor UniProtKB/Swiss-Prot
PRINTS TYRKINASE UniProtKB/Swiss-Prot
PROSITE EPH_LBD UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_1 UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_2 UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
SMART EPH_lbd UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot
UniProt EPHB6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Ephb6  Eph receptor B6  LOC102554290  serine/arginine repetitive matrix protein 2-like  Data Merged 737654 PROVISIONAL
2013-12-18 LOC102554290  serine/arginine repetitive matrix protein 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Ephb6  Eph receptor B6  Ephb6_predicted  Eph receptor B6 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ephb6_predicted  Eph receptor B6 (predicted)      Symbol and Name status set to approved 70820 APPROVED